Red Light Therapy - 101

We are not just made of biochemical matter. We are charged energy beings, constantly interacting with the environment. Light plays a crucial role in this natural process. Comprehensive new research has unearthed a full new understanding of how our cells function optimally. Food is not the only way we obtain energy; the light also charges us.

Science now shows your body operates like a battery. Certain wavelengths of sunlight power it, and your general health is determined by your ability to receive and maintain a charge. This is what light therapy is about.

What is Red Light Therapy

Light at certain wavelengths is scientifically proven to interact with the body in beneficial ways.

Red light, comprising both red and near-infrared wavelengths, is a unique healing part of the electromagnetic spectrum, and it is one of the most natural ways to charge the body. It is now used as a new form of therapy under the umbrella term Photobiomodulation(PBM)

Red light wavelengths ranging from 600–680nm. Red light boosts the formation of collagen and elastin and assists in cell communication. It penetrates superficially and can be used for skin conditions.

Near-Infrared wavelengths ranging from 750–850nm. NIR stimulates healing, increases mitochondrial function, and improves blood flow and tissue oxygenation. It penetrates deeper into the body.

A high-quality home device like those produced by Kaiyan uses medical-grade LEDs to shine natural red and near-infrared light on your body. Like the wavelengths of light your body needs from natural sunlight, without the heat or UV rays that cause sun damage and without the need for sunny weather. Check the list of best light therapy masks.

How to Recharge your Body

Electric charge is a fundamental property of the body. The surfaces in our bodies — such as membranes, proteins, and DNA — are all charged, negatively or positively, depending on whether they lose or gain electrons.

At the core of your body’s power to heal itself are sub-cellar organelles called mitochondria. The number of mitochondria in a cell varies widely by organism, tissue, and cell type and are concentrated in organs with high energy demands such as the brain, heart, liver, skin, and muscles.

This is because mitochondria generate most of the body's chemical energy supply via the ATP (adenosine triphosphate). They also regulate various other tasks, such as signaling, cellular differentiation, and maintaining control of the cell cycle and cell growth. This is why they are often referred to as the powerhouse of the cell.

Mitochondria
  1. LED light at a wavelength from 600–680nm(red) and between 810–850nm(infrared) is delivered to the tissue via the red light therapy device.
  2. The light enters the cell’s mitochondria and is absorbed by the chromophores, including the protein cytochrome c oxidase(CCO) and EZ water, increasing its activity.
  3. As a result of this highlighted activity, three molecules are affected. Adenosine Triphosphate(ATP), Reactive Oxygen Species (ROS), and Nitric Oxide (NO).
Water

Approximately 70% of our body weight and 99% of our bodies ’ molecules are made of water, and this water is in a charged state.

Recent research by Prof Gerald Pollock of the University of Washington has shown that water adjacent to a cell or mitochondrial membrane is so-called structured water. This is also called EZ (exclusion zone) water because it creates a separation of charge. Positive proton is excluded and pushed to the bulk water, and a lattice-like negatively charged water for near the membrane. This increases the voltage across the membrane—this charge separation of water in the body functions as the positive and negative poles of a battery.

What Does “Red Light Therapy” Mean?

As a term, “red light therapy” refers to treatments from LEDs or cold lasers that deliver wavelengths of natural red and near-infrared light.

The term does not include white light, blue light, or blue LED masks, and it is not the same as full-spectrum light. Some people may include infrared or far-infrared wavelengths along with red light therapy, but those are typically used in dry saunas because of their ability to produce heat. Red light therapy does not rely on heat, a major difference between natural light treatments and heat-based modalities like an infrared sauna, traditional sauna, or other heat therapy type.

Generally, “red light therapy” describes natural light treatments that deliver the same therapeutic red and near-infrared wavelengths as natural sunlight. This differs from artificial light treatments like tanning — or bright light therapy from light therapy lamps, lightboxes, or happy-light if you’re interested in natural light treatments for seasonal affective disorder.

The following terms may also call red light therapy: RLT, photobiomodulation (PBM), phototherapy, LED therapy, LED light therapy, infrared therapy, low-level laser therapy, or low-level light therapy (LLLT).

A Multilevel Treatment

Red light therapy works on multiple levels in the body.

Molecular

  • Chromophores, cytochrome c oxidase, water, opsins
  • Retrograde mitochondrial signaling
  • Light-sensitive ion channels
  • Adenosine triphosphate ATP
  • Reactive Oxygen Species ROS

Calcium

  • Heat-shock proteins
  • Melatonin
  • Brain-derived neurotrophic factor
  • Gene transcription factors
  • Akt/mTOR/CyclinD1 pathway

Cellular

  • Inflammation, Cytoprotection, Proliferation
  • Protein synthesis
  • Stem cell production and migration
  • Immune cell viability
  • Retrograde mitochondrial signaling
  • Transforming growth factor
  • Pro-and anti-inflammatory cytokines
  • Vascular endothelial
  • Mitochondrial membrane potential

Tissue

  • Muscles: Increase endurance, tone density
  • Brain: Improves cognition and immune
  • Nerves: Repair and pain relief
  • Healing: Bones, tendons, and wounds
  • Hair: Increases growth
  • Skin: Improvements of the collagen network, anti-aging, skin disorders
  • Fat: Fat re-absorption improved by enhanced micro-circulation
  • Lymph: Improved immunity
Systemic Effects

Red light therapy affects multiple bodily systems:

Fascia

The fascia is a complex web of sensitive and highly interconnected connective tissue beneath the skin that attaches, stabilizes, encloses, and separates muscles and other internal organs.

Fascia is primarily made from hydrated collagen-Protein chains in a triple helix formation surrounded by water, with a capacity to generate an electric charge in response to applied mechanical stress (piezoelectric).

The bio-electrical nature of the collagen-rich matrix is the key to understanding how pathological changes in one part of the body may cause a cascade of “remote effects” in seemingly unrelated areas and organ systems. The fascia is the long-overlooked but absolutely crucial interconnecting organ of the human body. The therapeutic effect of red light energy can be carried through the fascia network to other parts of the body where it is needed. This is turn, elevates the body’s capacity to communicate via this charged matrix in a positive feedback loop.

The well-known energy meridians of traditional Chinese medicine may actually be low resistance pathways operating through the fascia, conveying energy to the rest of the body.

Gut-Brain Axis

The gut-brain axis links the emotional and cognitive center of the brain with peripheral intestinal functions. Red light energy applied to the abdomen area can therefore influence mood and neuropsychological issues via several mechanisms:

  • Reduction in bowel inflammation and gut spasms.
  • Stimulation of neurotransmitters and hormones in the gut, including serotonin, leptin, and ghrelin.
  • Modulation of the micro-biome. The gut microbes are sensitive to light energy and respond to light energy with differences in growth, migration, and proliferation of the different species.
  • The increasing availability of neurotransmitters activates the brain’s immune system, increases blood flow, and removes toxins.
  • Increased blood circulation and reduced blood pressure leading to a reduction of anxiety and brain fog.
  • Modulation of the vagus nerve, one of the biggest nerves connecting the gut and brain. This plays an important role in stress and social communication, communicating motor and sensory impulses to every organ in the body.

Immune System

Beaming red light and near-infrared light onto cells creates a short, low-dose metabolic stress that builds up the cells' anti-inflammatory, anti-oxidant, and natural defense systems, making the body stronger and more resilient to infections.

This is the concept of hormesis; safe, low-level exposure to stressor results in increased resistance to illness. Red light has been shown to influence the immune response in several ways:

  • Activation of the mast cells leading to the movement of leukocytes and reduced inflammation.
  • Mast cell DE-granulation and the release of pro-inflammatory cytokines.
  • Increased infiltration of the tissues by leukocytes.
  • Enhanced proliferation, maturation, and motility of fibroblasts
  • Increased production of fibroblast growth factor.
  • Lymphocyte activation and proliferation.
  • Macro-phages activated to act as phagocytes.

Circulatory System

Red light therapy has been shown to aid the circulatory system's functioning and increase the micro-circulation of blood, one of the most recognized and well-documented effects of this therapy.

Red light stimulates the formation of new capillaries carrying more oxygen to the body.

A good oxygen supply is intricately involved in numerous biological processes, including cell proliferation, angiogenesis, and protein synthesis, required to restore tissue function and integrity.

Increased circulation allows for waste products to be carried away more effectively. It triggers and heightens the body’s own scavenging process for and ingesting degenerated cells for clean-up.

In fact, increased micro-circulation of blood is thought to be the most vital function for healing the body for almost every illness. For general well-being, Nutrient-rich blood and efficient waste removal is strongly linked to good health.

Nervous System

The nervous system is a complex electrical system, including the brain and spinal cord. It collects, processes, and responds to the input of energy-be it light, sound, heat, or pressure — and it relays these messages to the brain and around the body.

Red light energy affects the nervous system in several crucial ways:

  • Myelination of fibers and a better lamellar organization of the myelin sheath.
  • Improvement of electrophysiological function.
  • Facilitation of neural regeneration.
  • Release of growth factors.
  • Increase of vascular network and collagen.
  • Faster regeneration of nerve lesions and functional improvement of damaged nerves.

The peripheral nerves can be damaged by infection or high sugar levels in the case of diabetic neuropathy.

Red light therapy is being explored as a promising drug-free therapy for all kinds of nerve damage.

Stem Cells

At the frontier of science, red light therapy shows huge promise in current research to stimulate the growth of stem cells in the body and maximize the effect of stem cell implantation for a wide variety of medical purposes.

Therefore, red light may be useful after surgery to stimulate stem cells to aid the repair of tissues and possibly organs.

Light at certain wavelengths has also been shown to coax stem cells to repair teeth, so red light therapy could soon revolutionize dental treatments. Indeed, some progressive dental clinics now offer red light therapy as an alternative to conventional drug and drill treatments.

Red light therapy has been shown to stimulate mesenchymal stem cells in the bone marrow to enhance their capacity to infiltrate the brain.

This has implications for healing degenerative conditions such as dementia, Alzheimer’s, and Parkinson’s disease , currently lacking any orthodox treatment solution.

Where Did Red Light Therapy Come From?

Red light therapy has become a popular natural health intervention, both in professional settings and with home devices.

Light therapy technology has been used in medicine for decades, and NASA experimented with red light therapy use in space in the 1980s and 1990s. In the last 10–20 years, red light therapy has become more widely used thanks to breakthroughs in LED lighting technology that have made affordable home devices possible.

Major advances in clinical light therapy research, and increased public interest in natural health technologies, have also contributed to the growing use and popularity of red light therapy.

In 2016, Kaiyan Medical was the first red light therapy manufacturer to offer affordable, medical-grade devices to consumers for convenient, at-home use.

Relieve Pain And Discomfort

In humans, photobiomodulation is reportedly effective against various pain conditions, including mucositis, carpal tunnel syndrome, orthodontic pain, temporomandibular joint pain, neck pain, neuropathic pain from amputation, and menstrual cramps.

Red light therapy significantly reduces the severity of pain hypersensitivity while improving sensorimotor function.

These improvements are preceded by an anti-inflammatory microglia/macrophage cell population in the injury zone, thereby providing a lasting pain relief effect.

Red light therapy has been shown to yield effective pain relief via the modulation of multiple mechanisms:

  • Inhibitory cyclooxygenase and prostaglandins
  • Modulating nerve transmission
  • Increasing endorphins serotonin release
  • Stimulating metabolism
  • Activating peripheral opioid receptors
Repair Skin

Red light therapy is used for the rapid and safe healing of wounds from burns, surgery incisions, scars, diabetic neuropathy, ulcers, and bedsores.

Faster and better wound healing was one of NASA’s original findings and one of the key recognized uses for this technology. Red and near-infrared light promote beneficial effects during all four phases of the wound-healing process:

  • Coagulation
  • Inflammation
  • Migration
  • Remodeling

These processes are regulated by many growth factors connected with nitric oxide (NO) signaling release, which is modulated by light energy.

A major typical inhibiting factor for the body’s ability to recover from a wound is low oxygen flow. Therefore, the unique ability of red light to increase oxygen flow to the affected area has a massive effect on the healing process.

By reducing inflammation, oxygenation of the area, and formation of new blood vessels, a rapid healing process unfolds with less pain and scarring.

Red light energy may also reduce or prevent the need for pharmaceutical painkiller medication during the healing process.

Revive Immunity

If your body is energized on a cellular level and communication between the organ systems is efficient, your body will naturally develop disease resistance.

Your immune defense works to fend off bacteria and viruses all the time. Red light therapy boosts this system in several ways.

It releases nitric oxide and melatonin, which are involved in DNA repair and have a powerful antimicrobial effect.

It also works through a process known as hormesis. When red and near-infrared light is beamed into cells, it causes mild metabolic stress, which results in cells engaging their anti-inflammatory and antioxidant response.

In this way, the body is primed and ready to respond better to infections. Boosted immunity is also a natural consequence of other systemic effects of red light therapy.

Studies have shown a variety of benefits to the immune system:

  • Improved melatonin production
  • Improved antioxidant production
  • Increased micro-circulation enabling the transportation of immune cells.
  • Promotes activity in the lymph nodes
  • Increased NO levels
  • Better flow of neurotransmitters
  • Boosted collagen and elastin production
  • The more efficient function of cells and organelles
  • Boosts T cells pre-operatively
  • Improved thyroid function
Reduce Inflammation

Inflammation can be acute and topical ( short-lived, caused by accidents, sprains, and infections ), chronic and general ( long-term, caused by persistent conditions ).

While acute inflammation is a healthy physical healing response, chronic and general inflammation can be detrimental to health and often goes undetected.

Currently, the main treatment for inflammation in the body is NSAID or steroid drugs, both of which have side effects and disrupt the body's healing process. Red light therapy stimulates the body to activate its own healing mechanism, dramatically reducing the health risks associated with long term drug use.

Red light therapy works by decreasing the number of inflammatory cells, increasing fibroblast proliferation ( the cell that synthesizes the extra-cellular matrix and collagen ), stimulating angiogenesis ( the formation of new blood vessels ), and activating the body’s innate anti-inflammatory, antioxidant defenses.

The following conditions, associated with chronic and acute inflammation, are currently being investigated as highly promising targets for red light therapy.

  • Arthritis
  • Asthma
  • Sinusitis
  • Muscular sprains
  • Fibro-myalgia
  • Neuron inflammatory disorders such as Alzheimer’s
  • Irritable bowel syndrome and colitis
  • Rheumatic conditions
Regain Performance

Red light therapy has become a hot topic in sports and performance. Not only is it safe and non-toxic-it yields rapid and lasting results in many areas of application.

Besides the overwhelmingly beneficial effects on health overall, red light therapy supports muscle growth and repair by increasing the amount of ATP available, which allows for better performance and faster recovery.

Red light therapy used before training is known to prepare and strengthen the body and physical exertion to help with recovery.

Documented effects from red light therapy include:

  • Reducing DOMS ( Delayed Onset Muscle Soreness )
  • Greater endurance and performance
  • Improving sleep quality
  • Increasing sexual function and libido ( Including Testosterone )
  • Aiding weight loss
  • Boosting cognitive function
  • Reversing skin aging
  • Reducing cellulite
Red Light Therapy for Depression and Seasonal Affective Disorder

Seasonal affective disorder (SAD) is a type of depression that impacts at least 5% of Americans, especially in the winter months, when natural light exposure is lowest. SAD is also called seasonal depression, winter depression, or the winter blues.

Some people treat SAD symptoms with treatment options like bright white light therapies that mimic the sun’s light intensity at a bright time of day.

More researchers and physicians have used natural light treatments like red light therapy to help with natural light deficiency and the winter blues in recent years in conjunction with antidepressant medication and psychotherapy.

Who Uses Red Light Therapy?

In addition to the growing number of people using red light therapy devices in their home, red light therapy systems can be found in many professional and clinical settings:

Skincare Professionals: Red light therapy is a popular skin treatment among Hollywood celebrities for anti-aging, and it’s used by leading skincare professionals like estheticians and dermatologists to treat skin conditions and promote collagen production.

Health Practitioners: Red light therapy is an emerging subspecialty of medicine in a wide range of fields. From oncologists treating cancer side effects, to dentists reducing oral inflammation, to physicians treating mental health conditions, red light therapy is becoming more widespread in clinical practice.

Natural Health Experts: Leading voices in natural health and wellness like Dr. Sarah Ballantyne, Dave Asprey, and Ben Greenfield use red light therapy. So do Paleo and Keto health experts like Mark Sisson, Dr. Anthony Gustin, Luke Storey, and Robb Wolf.

Sports Medicine Pros: Light therapy companies work side by side with the National Association of Sports Medicine (NASM), and red light therapy is used to heal sports injuries by sports medicine professionals across the globe. Including the top trainers and doctors on the PGA Tour, like Dr. Troy Van Biezen and Dr. Ara Suppiah.

Elite Pro Athletes: Red light therapy is a popular training tool across pro sports, from NFL stars like Patrick Peterson, to UFC champs like Anthony Pettis, to gold medal gymnast Sanne Wevers.

Fitness & Training: World-class personal trainers like Lacey Stone and Jorge Cruise use red light therapy to both enhance performance and improve the muscle recovery process.

Supportive Cancer Care: The Multinational Association of Supportive Care in Cancer (MASCC) recommends red light therapy for the treatment of oral mucositis (OM), a common and debilitating symptom of cancer treatment.

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Lighting the Hidden Wounds: The Trauma from Human Trafficking

Lighting the Hidden Wounds: The Trauma from Human Trafficking

Human Trafficking

Human trafficking involves force, fraud, or coercion to obtain some labor or commercial sex act. Every year, millions of men, women, and children are trafficked worldwide — including the United States. It can happen in any community, and victims can be of any age, race, gender, or nationality. Traffickers might use violence, manipulation, or false promises of well-paying jobs or romantic relationships to lure victims into trafficking situations.

Traumas

Recent trauma studies have deepened our understanding of trauma and its impact. They describe a complex range of post-trauma symptoms and identify the interactions of multiple factors as contributing to their seriousness. For example, more serious symptoms are associated with histories of multiple victimizations, often beginning in childhood and disrupting parent-child relationships. More profound impacts are also associated with co-occurring behavioral health problems, like substance abuse disorders, and with a range of other issues, like limited social supports, lower socioeconomic status, and stigma associated with particular traumatic events. Trauma exposure occurs along a continuum of “complexity,” from the less complex single, adult-onset incident (e.g., a car accident) where all else is stable in a person’s life, to the repeated and intrusive trauma “frequently of an interpersonal nature, often involving a significant amount of stigma or shame” and where an individual may be more vulnerable, due to a variety of factors, to its effects. On this far end of the continuum, victims of human trafficking, especially sex trafficking, can be placed.

Post-trauma responses for victims of human trafficking

Most of the literature on trauma and trafficking focuses on the trafficking of foreign-born women and girls for commercial sexual exploitation. In addition to experiencing terrorizing physical and sexual violence, researchers report that victims often experience multiple layers of trauma, including psychological damage from captivity and fear of reprisals if escape is contemplated, brainwashing, and for some, a long history of family, community, or national violence. Additionally, the emotional effects of trauma can be persistent and devastating. Victims of human trafficking may suffer from anxiety, panic disorder, major depression, substance abuse, eating disorders, and a combination of these. For some victims, the trauma induced by someone they once trusted results in pervasive mistrust of others and their motives. This impact of trauma can make the job of first responders and those trying to help victims difficult at best. In some cases, exposure to trauma results in a condition referred to as Post-Traumatic Stress Disorder (PTSD). PTSD is a mental health diagnostic category created originally for war combatants and disaster victims and applies to victims of other traumas, including trafficking victims. For those that struggle with PTSD, the characterizing symptoms include intrusive re-experiencing of the trauma (e.g., flashbacks, nightmares, and intrusive thoughts), avoidance or numbing of trauma-related, or trauma-triggering stimuli (e.g., avoiding certain places, people, and situations), and hyperarousal (e.g., heightened startle response, and inability to concentrate). Once established, for both adults and youth, PTSD is usually chronic and debilitating if left untreated. Post-trauma responses like those outlined above reportedly contribute to problems with functioning, including difficulties controlling emotions, sudden outbursts of anger or self-mutilation, difficulties concentrating, suicidal behaviors, alterations in consciousness, and increased risk-taking.

Limited availability and access to appropriate mental health services.

Issues of affordability and access to services and the responsiveness of those services to the complex needs of survivors are common issues identified by service providers. Providers uniformly point to access to mental health services as a significant challenge for both international and domestic victims. For most victims, shame is seen as one of the greatest barriers preventing them from seeking mental health services. Providers note that the stigma associated with mental illness is an especially prominent challenge in engaging foreign-born and male victims in treatment. For other victims, while providers report a willingness to seek help for physical health complaints, the underlying cause of the physical problems or symptoms — the trauma — often goes ignored and untreated. For U.S. minor victims, barriers to accessing mental health services are linked primarily to the issues of confidentiality and concerns that someone will find out what has happened to them, lack of identification documents, lack of insurance, and system-related jurisdictional issues. For example, it is often assumed that child welfare systems will provide mental health services for minors. 2 Requirements to report minors to child protective services do not necessarily result in access to treatment. If a parent or legal guardian does not inflict the abuse, the case is often seen as outside the system's jurisdiction. In such cases, the minors fall through the cracks and do not receive the services they need. But there are still challenges even if a youth has health insurance or is served under the child welfare system. Most providers note that referral sources for mental health treatment or counseling are limited for youth and adults. In one community, the wait for a psychiatric referral for youth was up to seven months. Once access to mental health or counseling services is obtained, many providers cannot maintain the long-term treatment that many victims require. Providers report that insurance and/or funding restrictions often limit the number of sessions a victim can receive. Furthermore, traditional therapeutic services are often ill-designed to respond to transient victim populations' needs, particularly U.S. minor victims, who sometimes find it difficult to meet expectations for weekly appointments. Responsive mental health treatment requires considerable flexibility, which existing systems of care may not support. Therefore, while getting services in response to the immediate crisis is not viewed as a problem in most cases, helping a victim with long-term trauma recovery is a significant concern.

The new therapy: Red Light

During the last 20 years, a large body of research has accumulated on the beneficial effects of infrared light in the range of 600 to 1000 nm. Infrared light can activate mitochondria, stimulating second messenger systems, DNA transcription, and growth factors. As a result, new synapses are formed, circuits regrow, and pluripotent stem cells differentiate into neurons.

Animal studies have shown that infrared photobiomodulation (PBM) may reduce the size and severity of brain injury and stroke and diminish damage and physiological symptoms in depression, post-traumatic stress disorder (PTSD), Parkinson's disease, and Alzheimer's disease.  Michael Hamblin, Ph.D., from the Wellman Center for Photomedicine at Massachusetts General Hospital in Boston, a leader in the field, describes PBM as “the use of red or near-infrared light to stimulate, heal, regenerate, and protect tissue that has either been injured, is degenerating, or else is at risk of dying.”

Can Infrared Light Reach the Brain?

The human scalp and skull provide a significant barrier. Infrared light energy needs to be in the range of 0.9 to 15 J/cm2 at the target tissue to activate mitochondria and other cellular events. Even if a 0.5-W LED only had to penetrate the skull to reach the surface of the brain, it could only deliver 0.0064 J/cm2 or 1/140th of the minimum energy necessary to induce PBM. No energy would be expected to reach the depths of the brain needed to treat stroke, Parkinson's disease, Alzheimer's disease, or many brain injuries.

Treating TBI, PTSD, and Depression with Infrared Light

Patented Kaiyan Medical light therapy products involve transcranial infrared laser treatment (NILT). Our devices are based on clinical trials with significant clinical improvement of symptoms, including headaches, cognitive problems, sleep disturbances, irritability, and depression.

An open-label clinical trial (n=39) demonstrated effectiveness for depression. Overall, 92% of patients responded, and 82% remitted, which is notably better than the response rate for oral antidepressants. Patients saw benefits within 4 treatments, and some achieved resolution of depressive symptoms within 8 treatments. I

At Kaiyan, every day, we reconsider the potential mechanisms underlying the meager improvements derived from LED-based devices. The light from LED devices may not penetrate beyond the skin in some cases. Still, it could induce central nervous system benefits via a remote or systemic effect in irradiated skin, dubbed remote photobiomodulation.

Sources

Study of HHS Programs Serving Human Trafficking Victims
Principal Investigator: Heather Clawson Caliber, an ICF International Company Prepared for: Office of the Assistant…aspe.hhs.gov

Our Work: Industries, Services, and Clients
Our expertise is focused in highly regulated markets tackling many of the world's biggest ongoing challenges. Our…www.icfi.com

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Give Mom the Gift of Beauty from Within this Mother's Day

Give Mom the Gift of Beauty from Within this Mother's Day

With Mother's day right around the corner, you're probably wondering what to get her. It's easy to stick to the traditional—gifts, flowers, jewelry, or a gift card. But do these really show your appreciation to her for everything she's done for you? In reality, most mothers' day gifts aren't really that useful. Sure, a framed fame photo or a personalized mug is nice, but why not get her something that improves her well-being and makes her feel better in her own skin? 

Have you heard of the Aduro 7-in-1 Led face mask? If this is the first time you’ve heard about red light therapy, well, you just found the perfect mother's day gift. As women get older, they want to hold onto their youthfulness and this device is how they can achieve this goal. But before we talk about how skin care light therapy works, it's important you understand how light therapy functions and its many benefits.

Light therapy uses different types of light to act as a source of energy for the cells. When light penetrates the skin, the ATP (adenosine triphosphate) is stimulated. ATP acts to fuel your body's cells. Once stimulated, the body works to repair and rejuvenate damaged and old cells. Now, the body does this naturally; however, light therapy accelerates the process; thus, light therapy users see results within days. 

Naturally, light therapy can be used on a variety of areas of the body and can help with issues ranging from joint pain, to muscle recovery, to Seasonal Affective Disorder. But the Aduro 7-in-1 LED face mask focuses on promoting skin healing and collagen production. As we age, our skin's elasticity and collagen production decrease, creating fine lines and wrinkles. However, through Aduro's 7-in-1 light therapy mask, you can literally reverse signs of aging. 

The Aduro mask is one of the most advanced at-home LED facial masks on the market, featuring 11 different light treatments for a variety of skin conditions, from acne to pigmentation to rosacea. If you're wondering, “do light therapy masks really work?” The answer is “yes!” You just need to make sure you give yourself between 15-20 minutes per day to wear the mask. That's all that needs to be done. From there, you let the mask do its job.

The hands-free device has settings for blue, green, red, amber, and purple light. You can combine them to get the desired results. For example, blue light kills bacteria, red light is anti-inflammatory, and green light fights hyperpigmentation. So, it can be adjusted depending on the needs of the individual. Our skin’s needs fluctuate over time, and this mask works perfectly for all ages and skin types. 

While most at-home treatments require you to hold the device, this face mask stays on without having to touch it. So, your mom will be able to use her phone, meditate, listen to a podcast, all while the mask does its work. 

The best part is that light therapy has been well-researched and used for decades. So, if you’ve been wondering whether light therapy face masks are safe, yes, they are. Many skin experts have weighed in and studied the safety and efficacy of light treatments. 

More importantly, Kayian's red light therapy devices are FDA-approved and MDA-certified. While many light therapy masks on the market provide weak light with limited effects on the skin, Kayian's light therapy devices are not only regulated, but they work as non-invasive at-home treatments. So, this mother's day, why not treat your mom to a gift that she'll actually benefit from? Once she sees the benefits, she'll fall in love with the Aduro 7-in-1 light therapy mask and never want to take it off!

For more information on our manufacturing and private label offering, please reach out to our team – we love working with skincare experts on building their dream devices. 

P.S. - we're currently offering a Mother's Day promo on our site! Head to our product page to learn about the free gift with purchase we're offering.

Light Therapy & Acne Treatment

Light Therapy & Acne Treatment

We all know what acne is—for many, just hearing the word is traumatizing. While not everyone’s had to deal with it, many people do; and despite the fact that it’s an extremely common skin condition, it can be extremely challenging both emotionally and physically. 

You’d be surprised at how many people think “just washing your face” will help acne, or that there’s a miracle skincare product to cure. This generally not the reality, as acne occurs at an internal, cellular level in many cases. 

The types of acne vary, from acne that you don’t really notice, to acne that literally hurts. The reason to treat your acne shouldn’t be superficial, you should take into account that acne may be a sign of something going on within your body, for example, hormonal acne. But whether it is hormonal, genetic, cystic, or any of the many variants, acne is treatable, while there is no guaranteed cure. 

And, the more serious acne types are often treated medically. While many people don't want to take medication, most don't feel they have any other choice. There are dozens of different acids, creams, and antibiotics that are prescribed to treat acne. While they can work, they can also leave you with unpleasant side effects.

But what about light therapy for acne treatment? 

Not only does light therapy work on improving your acne, but it’s also focused on working from the inside out. Light therapy works at the cellular level, accelerating ATP production and cell turnover. This provides your skin with a new, healthier coat, eventually replacing old and dead skin cells. While your skin naturally dies and regenerates itself, light therapy accelerates the regeneration process with younger and stronger cells. 

Blue light therapy, for instance, is used to specifically combat skin bacteria that can lead to the development of acne. LED light therapy shows that 77% of acne cases that have been treated with blue light therapy have shown improved skin condition.Overall, people have experienced a significant decrease in the number of acne lesions, both pimples and cysts, with the at-home light therapy device. 

Light therapy is a non-harmful, non-irritating, and non-invasive skincare treatment. It’s not magic, but it has proven to be highly effective in treating acne. Studies support that it is antibacterial, anti-inflammatory, and has virtually no side effects. 

LED light therapy for hyperpigmentation also works to improve spots or discoloration post-acne, returning the skin to normal pigmentation levels. An increase in melanin is what causes our spots and hyperpigmentation, so to prevent it, light therapy could be you or your patients’ best friend. 

If you’re looking for a non-invasive, non-pharmaceutical acne treatment, a light therapy mask is what you want. Kayian's light therapy devices are for home use, MDA-certified and FDA-approved, ease-to-use, and effective for your own at-home treatment. You can take charge of your acne with light therapy, and if you’re a skincare practitioner, perhaps it’s time to consider private labeling your own device to better serve your clients by offering effective, safe products in-clinic, or even for your clients to use in the home.

Transitioning Skincare Routines from Winter to Spring

Transitioning Skincare Routines from Winter to Spring


The right skincare routine is something to be crafted meticulously. Not only is it individual––meaning that what’s best for one person might not work for another––but what’s best for a person in winter may not work for them during spring and summer. 

As we get older, naturally, so does our skin. As we age, our cells age, slowing down the cellular turnover process. With aging skin, there are certain needs to cater to that differ throughout the aging process. Ingredients that are good for mature skin could be too harsh for teenage skin, and vice-versa. 

Finding the right skincare for winter can be a challenge. The air is drier and harsher, making skin more prone to dryness and irritation. Of course, people can do things like sleeping with a humidifier in the room, eating clean, showering in warm water, and staying hydrated; and while these ideas do help to prevent flaky and dehydrated skin, they only work to a certain extent. 

While many stick to a strict winter skincare routine, following the same routine during spring and summer can actually be counterproductive in achieving the results desired. In the winter, most skincare enthusiasts use thicker and heavier products for hydration and protection; however, it’s important to just incorporate lighter products during spring time

Why can’t we use the same products all year round? Spring brings us different temperatures and climate. Humidity goes up, UV increases, and the temperature is warmer. The creams used during winter become too heavy during springtime, and the cleansers and moisturizers that helped skin in wintertime clog can sometimes pores during the spring and summer. However, there is a way to help transition skincare routines from winter to spring, and that’s with light therapy.

What is light therapy? Well, before we dive in, you may be wondering, ‘is light therapy treatment safe?’ Absolutely. It’s a non-invasive, and non-pharmaceutical treatment providing outstanding skincare results. It helps produce ATP, which provides the energy that runs our whole body. Through increased ATP, cellular turnover is improved with long-term light therapy treatments. 

Light therapy can help with the transition in the way that it prepares the skin for the change. It helps reprogram cell turnover, which provides fresher skin and balances out the natural nutrients our skin needs. This can help with getting ready for the transition of seasonal skincare products. 

Within one week, you or your client’s skin sees an improvement in ATP production, thus, reducing complexion, aging, and acne issues. By regenerating new cells, you’re likely witnessing a fresher face, and glowing skin. Naturally, the longer a person commits to light therapy, the better the results – all good things come with time. But light therapy presents a more powerful solution than simply relying on creams and serums, alone. With skincare products, the outer layer of the skin is repaired and the job gets halfway done. 

Getting used to a new skincare routine can take from 5-8 weeks, which is why it’s important to have the skin in the best possible condition in-between transitions. Light therapy helps reduce the chances of the negative effects that can easily occur in changing a skincare routine. Having the option to avoid irritation, acne, and redness comes simply by integrating light therapy into one’s facial routine.

However, irritation is sometimes inevitable, particularly in those with acne-prone or sensitive skin, and this can sometimes lead to hyperpigmentation and acne scars. But, luckily, this irritation and acne scarring can be treated at home with light therapy, as well. 

And, it’s ideal for dermatologists and aestheticians who want a non-invasive and non-pharmaceutical treatment for their clients in the treatment room. In addition, light therapy masks can be customized with multi or single light to suit your client’s needs. Kayian's light therapy devices are MDA-certified and FDA-approved, and created for clinical use. If you’re a dermatologist or aesthetician, you have the freedom of customizing your light therapy device to provide the best results for your clients. With a light therapy device in your office, you’ll give your clients the results they want, and have them coming back for more.

Neonatal Care Taps into Light Therapy

Neonatal Care Taps into Light Therapy

When a baby is born, all parents hope for a healthy child—all ten fingers and toes, a strong heart, and an able body. However, between 10 and 15 percent of babies born within the U.S. require special care within the NICU (Neonatal Intensive Care Unit), which is where preterm or diseased babies are cared for. 

This time is crucial for babies; it's the stage in which we, as humans, are most sensitive. After the first hour of life, newborns should receive eye care, vitamin K, and recommended immunizations (birth dose of OPV and Hepatitis B vaccine). They should be assessed for birth weight, fetal age, congenital disabilities, and newborn illness signs. Special care is provided for sick newborns, preterm and/or low birth weight, and babies exposed or infected by HIV or have congenital syphilis.

One of the more common diseases for premature babies is jaundice, which refers to the yellowish discoloration of the skin, sclerae, and mucous membranes caused by an increase in bilirubin in the blood. This substance derives from the metabolism of hemoglobin contained in red blood cells. For the newborn, it is (in most cases) destined to disappear within a few days.

Jaundice becomes evident when the amount of bilirubin exceeds 3 mg per deciliter. The yellowish color occurs first in the face and sclerae (the white part of the eye) and then extends to the trunk and upper and lower limbs. Jaundice can be physiological or indicate a pathology.

However, jaundice can become severe. This happens when it goes untreated for too long, it can cause a condition called kernicterus. Kernicterus is a type of brain damage resulting from high levels of bilirubin in a baby's blood. It can cause cerebral palsy and hearing loss.

Babies are naturally sensitive, and premature newborns are even more at risk. Their immune systems are still developing due to being born prematurely, which increases their risk of getting sick. Skin conditions of many kinds are common; in addition to jaundice, many experience feeding issues, and fever (always the first sign of an infection). 

Due to the nature of premature babies, it's essential to consider a non-invasive, non-medical treatment. They're still growing, just fully coming into their own and catching up on time missed developing in mom’s belly. 

Light therapy is an incredible tool for these little humans, working inward and targeting the cellular level. It helps with both external and internal problems, which means that at the cellular level, light therapy alters and enhances the cell constitution. This, as a result, leads to faster and better reproduction, creating a healthier and stronger organism and body to function with. 

Light therapy is a non-invasive, non-pharmaceutical form of therapy. The way it can help with neonatal care is unique. During treatments, the babies are completely safe and protected, with their eyes covered. The skin gets exposed to the light therapy lamp to absorb its benefits. The lamp is positioned specifically for the baby, no closer than 30.5cm. 

Light therapy has successfully treated newborn jaundice by lowering the bilirubin levels in the baby's blood through a process called photo-oxidation. Photo-oxidation adds oxygen to the bilirubin, making it dissolve in water easily. 

Since light therapy also helps to regulate circadian rhythm and melatonin, the treatments can also help babies sleep, which is essential in their healing and development. 


You can customize and completely control light therapy consumption for babies, thanks to Kaiyan Medical’s state-of-the-art light therapy device manufacturing services. We have been working for 15 years to produce the best light therapy products on the market which are MDA-certified and FDA-approved light therapy devices, many of which are cleared for at-home treatments. Of course, before using a light therapy device, always consult your doctor.

College Students use Light Therapy to Improve Seasonal Affective Disorder (SAD)

College Students use Light Therapy to Improve Seasonal Affective Disorder (SAD)

The life of a college student is taxing, to say the least. It's likely the first time you're doing something on your own, and are responsible for yourself, your schedule and lifestyle. For some, this is the most liberating time; for others, it’s incredibly overwhelming. However, there's a general agreement that college students all go through difficult times. 

Whether still living with parents or sharing a dorm or space with roommates, college students are immersed in an entirely new life experience. Classes are challenging and students struggle with getting their work done while maintaining a social life, and perhaps a job. The level of pressure to succeed is very demanding, and this can cause negatively associated thoughts, leading to stress. Eating habits change and alter, usually for the worst, not to mention that the new sense of freedom can be chaotic for many young adults. 

Taking care of yourself is the number one priority, and when learning to deal with the new load of responsibility, college students often get sidetracked. Health and self-care get only an ounce of attention and not nearly as much as it should. While many students think it takes a lot of effort, just starting small shows results. 

Stress is the precursor of everything in our body, and leads to all sorts of illness and disorders. It's pretty common for college students to experience stress; more than 40% of students claimed to have experienced above-average stress levels, with it getting worse during exam periods and the winter season, when even more time is spent indoors. All of this, compounded by a pandemic and social distancing, makes for extremely challenging circumstances for college students today.

Now, colleges such as the University of Iowa are turning to light therapy to help get students the light they need to continue thriving. 

Seasonal affective disorder (SAD) is a mood disorder that occurs annually, generally in fall and early winter, and ends in sunnier and warmer months of spring and early summer. However, it’s worth noting that it’s not a perfect formula; there have been reported cases of the opposite, where a person starts experiencing the disorder spring or summer, and it only ends with the arrival of fall/winter. 

SAD can affect 11 million people in the U.S. each year, and 25 million more may have a milder form of the same disorder, also known as winter blues. Depression and anxiety affect 40 million adults in America, while only 36.9% receive the proper care for these mental health conditions

And, SAD’s symptoms can look and feel much like depression. It causes you to sleep more and gives you symptoms that look like other disorders such as chronic fatigue syndrome, under-active thyroid, low blood sugar, viral illnesses, or other mood disorders.

Seasonal affective disorder is linked to a lack of sunlight. The winter days are shorter, and that itself our circadian rhythm, or internal body clock. Everyone has a specific sensitivity to sunlight, and our bodies take a cue from the morning sunlight each day. In the winter time, the lack of sunlight creates perfect circumstances to experience SAD.

Light therapy, by definition, gives you a healthy supply of what you lack in winter months, often leading to SAD. But light therapy is much more than that. Light therapy’s uses and benefits are many, so while treating SAD, you could also be treating other problems you may not even know of – it’s like killing multiple birds with one stone, and that stone happens to be safe, non-invasive, and non-pharmaceutical.

Light therapy mimics the positive effects produced by exposure to the sun. It reproduces the effects the sun provides us with, and can solve numerous symptoms of SAD through the use of ultraviolet rays. You may be wondering if red light therapy is safe for skin: yes, it is entirely safe. Specifically, with Kayian's light therapy devices, which are FDA-approved and MDA-certified.

With light therapy, you're able to stimulate your cells into rejuvenation. The light works directly at the cellular level and triggers the reproduction of ATP, the fuel our system needs to function properly. 

Light therapy helps with SAD by causing our brain to believe it's getting more sunlight. Even though the light is fabricated, it's still light. We still reap all of the benefits as we do from sun exposure. Melatonin and serotonin are what affects the impact; they too, are triggered by our light therapy devices, which is what battles SAD. 

The scientific evidence on light therapy and SAD says that even within the first hour, you may experience positive results. With daily use of light therapy, thousands of people have overcome the debilitating symptoms of SAD and other disorders, and now even college students can turn to the holistic treatment to replenish the light they’re lacking.

Alzheimer's and Light Therapy Treatment

Alzheimer's and Light Therapy Treatment

Losing our memory is something we all fear of. Alzheimer's disease is a very difficult, and the most common form of dementia. This general term refers to the loss of memory and other intellectual skills so severe that it interferes with daily life. Alzheimer's disease accounts for 50-80% of dementia cases.

Alzheimer's is a neurological disorder believed to have genetic components. It's thought to be caused by the abnormal build-up of proteins in and around brain cells; and Alzheimer's is not just a disease of old age, as it was once widely believed to be. Up to 5% of people suffering from this disease have an early onset of Alzheimer's disease (also known as "early-onset"), which often appears when a person is between forty and fifty years old. 

It is a life-altering disease and can be extremely challenging. It's not something that affects only the patient; it is a disease that alters the lives of those around you, as well.

The life expectancy after diagnosis is typically eight to ten years. Of course, this varies; a person can live up to 20 years post-diagnosis. Sometimes people don't get diagnosed for a few years, thus leading them to have less time. 

When Alzheimer's disease strikes, it initially presents symptoms that may be so mild that they go unnoticed by both the patient and his family; however, as the disease progresses, these symptoms become more evident and begin to interfere with daily activities and relationships.

The main symptoms are significant memory loss, difficulties in producing and understanding language, inability to recognize people, objects, or places, decoding external stimuli, and difficulty performing simple voluntary movements, such as using objects. As the disease progresses, psychiatric symptoms often occur, such as depression, anxiety, apathy, irritability, and even aggression.

A person with Alzheimer's needs a safe place and environment. Things must be kept simple, and their life significantly changes. You can't really expect a person suffering from this disorder to be the same. Their personality and behavioral changes are entirely normal.  

The list of light therapy uses and benefits goes on and on, as it is a form of treatment that can help with many health issues and disorders. However, for people with Alzheimer's, it can have a powerful effect on their experience.

Red light therapy is a form of therapy that works simply by producing light. There are many different devices, lightboxes, masks, and lamps that are used. The ultraviolet rays you receive in a light therapy session are the ones who directly target at the cellular level. Once the cells are penetrated by light, they accelerate at their reproductive level, increasing ATP production. ATP is the powerhouse of the mitochondria, essential for our system to function optimally.

A review of red light therapy is something we can all benefit from. There are no downsides to red light therapy, as it is a non-invasive and non-pharmaceutical procedure. 

Light therapy focuses on the cellular level. MRI imaging uncovered a 61% reduction in whole-brain atrophy and losses of volume in areas associated with Alzheimer's from red light therapy treatments. It works by rejuvenating the cells, creating new ones at a higher rate. Our organism benefits from cellular alteration because of the production of new cells. This means they're not only fresh cells, but they're stronger than before.

Light therapy masks help suppress Beta-amyloid (Aβ) build-up, the protein that forms senile plaques in the brains of people with Alzheimer's and dementia. So it's focusing on getting rid of the root of the problem. With a reduced build-up, our brain cells return to their natural state, the protein having been successfully eradicated.

Kaiyan specializes in light therapy devices that are MDA-certified and FDA-approved, making our product easy and accessible, perfect for at-home treatments – even for some of the most challenging diseases and health conditions.

Light Therapy's Market Outlook Through 2026

Light Therapy's Market Outlook Through 2026

Light therapy has been around for decades, and in the latest few, it’s been gaining momentum and the deserved acceptance from the medical community. The global light therapy market is booming, assumed to reach $1 billion by 2025. 

Some wonder about red light therapy's effectiveness and safety, but companies like Kayian receive FDA and MDA-certification to ensure consumers safety. Light therapy's medical benefits are extensive and range from aesthetics to deep full-body healing. Its countless benefits are why many are looking into this market for its wide range of possibilities. 

Being that it is a non-invasive and non-pharmaceutical form of therapy, light therapy has been challenged through the decades by the pharmaceutical industry. However, as you’re about to see, it’s clear that light therapy is making a breakthrough.

Light therapy's market was valued at over $1 billion in 2020 and is predicted to witness 5.1% CAGR from 2021 to 2027.

Rising incidences of skin-related disorders and growing awareness about care are the factors driving the sunshine therapy market growth.

North America dominated the worldwide light therapy market in 2018. The rise in the prevalence of skin disorders, including eczema and carcinoma in North America, drives the light therapy market. According to current studies by National Psoriasis Foundation, U.S., quite 8 million Americans have psoriasis. 

As per the American Academy of Dermatology (AAD), acne is the most common skin condition within the U.S., affecting up to 50 million Americans annually. An increase in investments from the government and various organizations is predicted to drive the light therapy market in North America.

There are many different product types within the light therapy market, but two main ones are infrared lamps and cold laser therapy. The difference is in the wavelengths. Both have a proven effect on ATP; the real differences preference since the benefits are mainly the same, albeit to a different degree. 

There are also light boxes, floor and desk lamps, light visors, HDST, dawn simulators, light therapy bulbs.

Handheld devices for skin (HDST) are projected to witness 5.6% growth rate till 2027. The light therapy market is estimated to attain a CAGR of 5.8% till 2027, accelerated by the increasing number of sleep disorders coupled with the growing use of light therapy to treat sleeping disorders.

Light therapy's main clinical applications are in biological time sleep disorders, dementia, mood disorders, and insomnia. With light therapy, 5000 lux/h administered daily over several weeks is common. Effects are long-term only if the therapy sessions are persistent and continuous.  

Light therapy is used in many areas of expertise but mainly in hospitals, surgical centers, and diagnostic centers. You can get treatment in a light therapy box perspired from a doctor. 

Some of the eminent players operating within the light therapy market are Beurer, Koninklijke Philips, Aura Daylight, Biophotas, Lucimed, Zepter International, Verilux, and Northern Light Technologies. 

The North American light therapy market size crossed USD 350 million in 2020 due to technological advancements, including growing light therapy applications. Moreover, the presence of major market players and merchandise availability will strengthen the regional market revenue growth.

The market is relied upon to predict vigorous development from constant mechanical headways. Symptoms and side effects of different procedures and constant advancement in light treatment therapy will move individuals' tendency towards light treatment.

In addition, expanding interest for cutting-edge skin and overall health management treatment, for example, blue light and red-light treatment, will help the market development. Also, the rising selection of non-intrusive treatments for different skin problems like wrinkles, facial redness, skin break out, and rosacea will significantly affect future market income.

The interest in blue light additionally expanded significantly during the COVID-19 pandemic. As indicated by medical care scientists, blue light act's as an antimicrobial against various microorganisms. It inactivates a few infections, including COVID and the basic seasonal infection.

Kaiyan Medical is a part of the booming market and our production of FDA-certified and MDA-certified light therapy devices are perfect for at-home treatments.

Injecting UV Light? - Ultraviolet blood irradiation (UBI)

Injecting UV Light? - Ultraviolet blood irradiation (UBI)

Ultraviolet blood irradiation (UBI) was extensively used in the 1940s and 1950s to treat many diseases, including septicemia, pneumonia, tuberculosis, arthritis, asthma, and even poliomyelitis. The early studies were carried out by several physicians in the USA and published in the American Journal of Surgery. However, with the development of antibiotics, UBI use declined, and it has now been called “the cure that time forgot.” Russian workers and other Eastern countries mostly performed later studies, and the modern view in Western countries is that UBI remains highly controversial.

No resistance of microorganisms to UV irradiation has been reported, and multi- antibiotic-resistant strains are as susceptible as their wild-type counterparts. Low and mild UV kill microorganisms by damaging the DNA, while DNA repair enzymes can rapidly repair any DNA damage in host cells. However, UBI treats septicemia cannot be solely due to UV-mediated killing of bacteria in the blood-stream, as only 5–7% of blood volume needs to be treated with UV to produce the optimum benefit. UBI may enhance the phagocytic capacity of various phagocytic cells (neutrophils and dendritic cells), inhibit lymphocytes, and oxidize blood lipids. The oxidative nature of UBI may have mechanisms in common with ozone therapy and other oxygen therapies.

Ultraviolet (UV)

Ultraviolet (UV) radiation is part of the electromagnetic spectrum with a wavelength range (100–400 nm) shorter than that of visible light (400–700 nm) but longer than x-rays (<100 nm). UV radiation is divided into four distinct spectral areas, including vacuum UV (100–200 nm), UVC (200–280 nm), UVB (280–315 nm), and UVA (315–400 nm). Only part of UVB and UVA can reach on earth because wavelengths shorter than 280 nm are filtered out by the atmosphere, especially by the “ozone layer.”

In the second half of the nineteenth century, the therapeutic application of sunlight known as heliotherapy gradually became popular. In 1855, Rikli from Switzerland opened a thermal station in Veldes in Slovenia to provide helio-therapy. In 1877, Downes and Blunt discovered by chance that sunlight could kill bacteria. They noted that sugar water placed on a window-sill turned cloudy in the shade but remained clear while in the sun. Upon microscopic examination of the two solutions, they realized that bacteria were growing in the shaded solution but not in the one exposed to sunlight.

Emmett K Knott in Seattle, WA, reasoned that the beneficial effects of UV irradiation to the skin obtained by Ude might be explained by the irradiation of blood circulating in the superficial capillaries of the skin. With his collaborator Edblom, an irradiation chamber was constructed to allow direct blood exposure to UV. The irradiation chamber was circular and contained a labyrinthine set of channels that connected the inlet and outlet ports. All these channels were covered with a quartz window that formed the top of the chamber. The irradiation chamber was designed to provide maximum turbulence of the blood flowing through. This was done to (a) prevent the formation of a thin film of blood on the chamber window that would absorb and filter out much of the UV light; (b) ensure that all the blood passing through the chamber was equally exposed to UV.

Mechanisms of Action of UBI

One of the major obstacles that UBI has consistently faced throughout the almost 90 years since the first patient was treated has been the lack of understanding of action mechanisms. Over the years, its acceptance by the broad medical community has been hindered by this uncertainty. Confusion has been caused by the widely held idea that since UV is used for sterilization of water and surgical instruments; therefore its use against infection must also rely on UV-mediated direct destruction of pathogens. Another highly confusing aspect is the wide assortment of diseases, which have been claimed to be successfully treated by UBI. It is often thought that something that appears to be “too good to be true” usually is.

UBI affects various functions of red blood cells and various leukocytes, as proven in various in vitro studies. A common model is stimulator cells in mixed leukocyte cultures; another is helper cells in mitogen-stimulated cultures. UV also reversed cytokine production and blocked cytokine release. UV can also disturb cell membrane mobilization.

Effects on Red Blood Cells

Anaerobic conditions strongly inhibited the process by which long-wave UV light induces the loss of K+ ions from red blood cells. Has been proved that UV-irradiation could affect the osmotic properties of red blood cells, the submicroscopic structure, and adenine nucleotides' metabolism. Irradiation times (60, 120, 180, 240, and 300 minutes) were used; during the irradiation, ATP decreased while the amounts of ADP, AXP, and adenine compounds increased. UV also increased hypotonic Na +, and K+ ion exchange and the hematocrit value increased.

A two-phase polymer system containing poly-dextran was used to show that circulating erythrocytes' cell surface was reduced after UV irradiation. This contributed to the prolongation of survival of transfused erythrocytes and was suggested to explain the more effective therapeutic activity of autotransfusion blood.

Effects on Lymphocytes (T-Cells and B-Cells)

UBI generally decreases lymphocyte viability. UVC irradiation is the most effective among the three UV spectral regions. UVB and UVC irradiation can abolish the proliferative and stimulatory ability and the accessory/ antigen-presenting ability of lymphocytes in vitro. The cell-surface properties, calcium mobilization, cytokine production and release, and other sub-cellular processes could all be changed by UV irradiation. Areltt et al. used the “Comet “assay to detect DNA-strand breakage (single-cell gel electrophoresis) as an indicator of excision repair to prove that circulating human T–lymphocytes were exquisitely hyper-sensitive to the DNA-damaging and lethal effects of UV-B radiation, raising the possibility that UV-B may contribute to immunosuppression via a direct effect on extra capillary T-lymphocytes.

Effects on Platelets

H2O2 production in platelets is low at a shallow UV dose, but it increased suddenly as the dose increased above 0.4 J/cm2. Pamphilon reported that platelet concentrates (PC) could become non-immunogenic after UVR and after being stored for 5 days in DuPont Stericell containers. Lactate levels, β-thrombomodulin, and platelet factor were higher after UV. In contrast, glucose levels decreased with an irradiation dose of 3000 J/m2 at a mean wavelength of 310 nm applied in DuPont Stericell bags. Ultraviolet B (UVB) irradiation of platelet concentrate (PC) accelerated downregulation of CD14 and nonspecifically increased the loss of monocytes by inhibiting the upregulation of ICAM-1 and HLA-DR. However, UV irradiation of platelet concentrates produced a reduction of immunological response in a cell suspension.

Things to consider before buying a UVC device

There are a few things you should consider before investing in a UVC wand or other UVC devices.

The first and most important thing to consider: safety. Experts have said UVC can affect skin cells the same way it kills bacteria; it can cause mutations in them and lead to skin cancer. Looking at UVC lights can cause irreversible blindness, too.

Here in Kaiyan Medical, we suggest that you look for UVC devices that come with safety switches — automatic “turn-off” buttons that halt the light emission as soon as you’re at risk of direct exposure.

The second thing to consider: the legitimacy of the product. We have seen some counterfeit UVC consumer products on the market. But unless you have a device at home that measures wavelength in realtime (aka a spectrometer), there’s no way of distinguishing products that use UVC rays versus other UV rays.

Conclusion

UV irradiation of blood was hailed as a miracle therapy for treating serious infections in the 1940s and 1950s. In an ironic quirk of fate, this historical time period coincided with the widespread introduction of penicillin antibiotics, which were rapidly found to be an even bigger medical miracle therapy. Moreover, another major success of UBI, which was becoming increasingly used to treat polio, was also eclipsed by the introduction of the Salk polio vaccine in 1955. UBI had originally been an American discovery but then was transitioned to being more studied in Russia and other eastern countries, which had long concentrated on physical therapies for many diseases, which were more usually treated with drugs in the West.

However, in the last decade, the problem of multi-antibiotic-resistant bacteria has grown relentlessly. Multidrug-resistant (MDR) and pan drug-resistant (PDR) bacterial strains and their related infections are emerging threats to public health throughout the world. These are associated with approximately two-fold higher mortality rates and considerably prolonged hospital admissions. The infections caused by antibiotic-resistant strains are often tough to treat due to the limited therapeutic options range. Recently in Feb 2015, the Review on Antimicrobial Resistance stated, “Drug-resistant infections could kill an extra 10 million people across the world every year by 2050 if they are not tackled. By this date, they could also cost the world around $100 trillion in the lost output: more than the size of the current world economy, and roughly equivalent to the world losing the output of the UK economy every year, for 35 years”.

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Product Spotlight: Aduro Mask

Product Spotlight: Aduro Mask


When trying out new forms of non-invasive treatments such as light therapy, it’s extremely important that you find something that satisfies your own needs. Finding a product that suits you isn’t always as easy, which is why many of us conduct our own due diligence before trying something new. 

Light therapy has been around for decades, but is making a serious comeback as its effectiveness and results become more widely known. The best part is it’s not only beneficial for gaining a youthful glow, but overall health as well. So if you’re interested in incorporating a mask into your practice, it’s time you checked out the Aduro Mask (and guess what – with Kaiyan, you can create a private-labeled, premium light therapy facial mask of your own, too)! 

“Although I have only used it a few times, I can state that as LED goes, this one is amazing. I am not new to LED, so I speak from experience when I say - WOW. It is comfortable and has a nice weight. But most importantly, it leaves your skin glowing and smooth. Cannot wait to see even more results the longer I use it.” - Mary F.

Our LED face mask is a light therapy device that uses different wavelengths to create 11 different treatments for many types of skin problems. It took inspiration from NASAs light therapy devices. It has 7 different LED light options, and when the selected light color penetrates the skin, photon energy is transferred to the cells. This is the basic principle of all light therapy devices. 

When the light penetrates the skin, cells convert this energy into ATP (our energy source) – stimulating cellular activity and reproduction. The boosted cells improve their rate and stimulate the body’s natural rejuvenation. This leads to an increase in collagen production and the body’s natural rejuvenation processes – resulting in youthful skin and an overall improvement in your skin’s complexion. The Aduro LED light therapy is mainly for skin rejuvenation and improving skin conditions, depending on the type of light used during treatment.

“I was excited first off that it shipped so quickly!! Packaged great, instructions were easy to read. I love the device. So many features. I can really tell a difference in my complexion after just a few days. The texture of my face and the fine lines. Definitely worth it. This was a birthday gift to myself… Thank you for a great product!!!” - Judy R.

For example, to treat the epidermis—the outer layer of the skin—red or infrared light is used. When applied to the epidermis, it absorbs light and stimulates collagen production. The skin, therefore, has more collagen, appears smoother and fuller, which can reduce the appearance of fine lines and wrinkles. 

Whereas blue LED light therapy focuses on the sebaceous glands. These are necessary to lubricate the skin and hair, but they can also become hyperactive and lead to oily skin and acne.

The blue light under the skin also destroys the bacteria that cause acne, which can help in the treatment of severe acne, including cysts and sebaceous nodules. Blue light is often used in combination with red LED light to heal acne, reduce scars and increase anti-inflammatory effects. 

And this is just an example of the power of light therapy. Our LED facial masks offer seven different forms of light that all have their own unique healing components. 

The treatments available with our LED face mask range from anti-aging to pain blockers. The mask can:

  • Increases hydration from the inside out
  • Help to even out skin pigmentation and redness
  • Even skin tone and clear complexion
  • Reduce acne
  • Revitalize and brighten the skin
  • Reduce eczema and rosacea for sensitive skin

The treatments are calming and purifying for all skin types. With our face mask, there are also options of treatments for skin above the age of 40 and a specific treatment for cell rejuvenation. Depending on your needs, you get to customize the light you want to include in your therapy treatment.  

I’m over 40 & just moved to the Caribbean. Hoping that this will help with my aging & help with the sun exposure. Just started the 20 minute session 3 days ago & it truly feels like it’s working some magic! The mask is very comfortable & overall I can tell it’s extremely well made. Very happy with my purchase & will update with my results in a few months!  - Sarah D.

In addition to cosmetic purposes, the LED mask cycles through all light wavelengths, known as the overall wellness setting, can help with Seasonal Affective Disorder ‘SAD’. 

Kaiyan Medical manufactures MDA-certified and FDA-approved laser light therapy devices that can be customized to exactly what your customer’s needs are. However, one thing’s for sure, customers are raving about the Aduro mask and can’t get enough of it.

“I’ve been using LED masks for several years. This is the third type of mask I’ve used. The results have been excellent. Better than any mask I’ve used in the past. My only problem was that my skin was sticking to the plastic during treatments which made it slightly uncomfortable. Using a hydrating mask during the treatment helped. I love the mobility it gives me. I’ve done five full treatments before recharging the battery. You may be able to get more I didn’t try. I’ve only had the mask a couple of weeks but at present I find it amazing.” -Rhoda K.


SAD - Seasonal Affective Disorder 101

SAD - Seasonal Affective Disorder 101

The first formal description of Seasonal Affective Disorder (SAD), the most well-known psychiatric condition associated with seasonality in humans, was introduced in the mid-1980s by Rosenthal, who described a group of 29 patients living in a temperate climate who experienced depressive episodes characterized by hypersomnia, hyperphagia, and weight gain in the fall or winter, and whose symptoms remitted by the next spring or summer.

SAD was incorporated into the Diagnostic and Statistical Manual (DSM) of Mental Disorders III-R when “seasonal pattern” was introduced as a specifier for Major Depression and Bipolar Disorders. Subsequent revision in DSM-IV described SAD as “a regular temporal relationship between the onset of Major Depressive Episodes in Bipolar I (BPI) or Bipolar II (BPII) Disorder or Major Depressive Disorder (MDD), recurrent, and a particular time of the year.”

Today, SAD, or MDD with seasonal pattern, is defined as recurrent episodes of major depression that meet the following criteria: at least two consecutive years where the onset and offset of depressive symptoms occur at characteristic times with no non-seasonal episodes, a temporal relationship between onset of symptoms and time of year, a temporal relationship between remission of symptoms and time of year, and an outnumbering of seasonal compared to non-seasonal episodes throughout the lifetime of the patient.

Pathophysiology of SAD

To date, the pathophysiology of SAD is unclear. Early research into the mechanism of SAD focused on day length or photoperiod. This hypothesis posited that shorter days in winter, possibly mediated by a longer duration of nocturnal melatonin secretion, leads to depressed mood in susceptible individuals. To date, there is little data to support this hypothesis. Furthermore, given that bright light in the evening has not been as effective as that given in the morning, it now seems unlikely that the photoperiod is the underlying pathological mechanism of SAD.

Although some animal studies have implicated a direct effect of light on the midbrain (Miller, Miller, Obermeyer, Behan, & Benca, 1999; Miller, Obermeyer, Behan, & Benca, 1998), the most prominent hypothesis driving human studies involves disruption of circadian rhythms. Research on the role of serotonin is also active.

Circadian Rhythm

A circadian rhythm refers to the approximately 24-hour cycle of physiological processes present in humans and other animals. This cycle is governed via clock gene expression by the suprachiasmatic nucleus (SCN), the master pacemaker located within the anterior hypothalamus. Though the SCN endogenously generates circadian oscillations, SCN endogenously generates circadian oscillations, and they need to be entrained to the 24-hour day by external cues. Light exposure is the most important synchronizing agent of endogenous circadian rhythms.

Downstream of the SCN, a collection of systemically active neurohumoral networks transduce circadian information to the rest of the body. For instance, via projections to the hypothalamus's paraventricular nucleus, the activation of the SCN leads to autonomic changes, including cardiovascular modulation, and together the central, peripheral, and autonomic nervous systems collaborate to affect systemic changes. Thus, the SCN receives information about the external day-night cycle directly through retinofugal pathways and indirectly through neuromodulatory signaling. Circadian information is then relayed systemically through neurohumoral networks.

The current primary hypothesis for the pathophysiology of SAD, known as the “phase-shift hypothesis,” posits that there is an optimal relationship in the alignment of the sleep-wake cycle and the endogenous circadian rhythm. During the fall and winter, as day length shortens, the circadian rhythm begins to drift later concerning clock time and the sleep-wake cycle. This phase delay is hypothesized to bring about mood symptoms. A pulse of morning bright light generates a circadian phase advance, which is thought to correct the discordance between sleep and circadian phase, thereby ameliorating depressive symptoms. However, the phase-shift hypothesis would predict that the amount of phase correction required for each patient would depend on an individual’s PAD, which has not yet been proven.

Serotonin

Several studies have also proposed that serotonin is implicated in the pathophysiology of SAD, as selective serotonin reuptake inhibitors (SSRIs) appear to be effective in the treatment of SAD. Supporting this hypothesis, one study used Positron Emission Tomography (PET) imaging to look at binding probability at synaptic serotonin transporters in 88 normal individuals living in the temperate climate of Toronto, Canada (Praschak-Rieder, Willeit, Wilson, Houle, & Meyer, 2008). The binding probability was increased during fall and winter compared to warmer months, thus eliciting an inverse correlation between binding potential and sunlight durationsunlight duration. Of note, the largest difference in transporter binding was found in the mesencephalon, a finding consistent with animal studies demonstrating the importance of direct effects of light to the midbrain on behavior. If increased transporter activity indicated greater reuptake of serotonin during the fall/winter, and if this resulted in a lower density of cleft serotonin, then the seasonal variation in transporter activity (i.e., higher transporter efficiency in the winter) would seem to leave susceptible individuals particularly prone to mood symptoms during the darker seasons. Moreover, following BLT and during periods of remission in the summer months, the synaptic transporter activity was shown to be reduced to control levels in these patients.

Eating Disorders

BLT has also been investigated to a lesser extent in eating disorders. Because binge eating episodes have been observed to increase in fall and winter in some patients, BLT has been examined as a treatment modality for anorexia nervosa (AN) and bulimia nervosa (BN). Thus, BLT's effects on patients with eating disorders remain enigmatic. Additional studies, including larger, randomized, blinded, and controlled trials, are needed to elucidate further the role of BLT in treating this patient population. Further research might also determine whether BLT would be a useful treatment in Binge-Eating Disorder, a diagnosis new to DSM-5.

Adult ADHD

Additionally, BLT has been studied in the context of adult Attention-Deficit/Hyperactivity Disorder (ADHD), where, in addition to normal ADHD symptoms, patients often have depressed mood and difficulties falling asleep, awakening on time, and maintaining arousal (Brown & McMullen, 2001). These symptoms are indicative of a possible delay in the circadian rhythm. A case report of symptom improvement following BLT in a child with ADHD who displayed signs of delayed sleep phase also supports the idea that BLT may be useful in treating symptoms of ADHD (Gruber, Grizenko, & Joober, 2007). Whether the pathways that subserve the improvement of mood symptoms in response to BLT are the same pathways that underlie the seemingly beneficial effects of BLT in ADHD remains to be studied. While these results are promising, further studies, preferably in randomized, blinded, and controlled studies will need to be performed.

Finally

A significant immediate reduction of depression scores with light treatment can be identified after 20 minutes and reaches the maximum at 40 minutes, with no additional benefit at 60 minutes. The rate of change is steepest during the first 20 minutes of light as compared with longer intervals. Comparing the clinical impact of these durations of administration may yield different results when measured after several daily sessions. The overnight effect on circadian rhythms and sleep was not assessed in our study and is thought to impact mood regulation in SAD. Larger, prospective, controlled, and hypothesis-driven studies in more naturalistic conditions would be desirable to replicate our study results and our study results and analyze the temporal dynamic of the persistence of the immediate mood-improvement effects. Besides, in larger samples, one could define early responders and nonresponders, analyze genetic (e.g., melanopsin related genes), demographic (children, adolescents, adults, elderly, gender), physiological (e.g., pupillary responses), and clinical (e.g., abundant atypical symptoms) predictors for early response. If proven effective and efficacious, shorter exposures to bright light could become a feasible and broadly employed intervention for immediate mood improvement as an early step on the road toward full antidepressant response and remission.


REFERENCES
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Retinol and Light Therapy: Skincare Dream Team

Retinol and Light Therapy: Skincare Dream Team

You’ve probably heard of retinol. It’s been in the skincare industry for years and it provides amazing results for non-invasive treatment. It helps with wrinkles, aging, hyperpigmentation, and in general can produce flawless-looking skin.

A derivative of vitamin A, Retinol helps cellular turnover, making it powerful enough to significantly improve skin texture, pigmentation, and tone. Through cellular turnover, it combats sun damage and skin loosening for its collagen properties. 

Not to mention, you only need a couple of drops. Studies have shown that the use of an over-the-counter product with 0.1% retinol (referred to as regular and prolonged use) brings significant improvement with wrinkles, collagen production, blood flow, and sunspots, with results visible after one month. 

Once applied, the retinol is absorbed, broken down, and transformed into retinoic acid. This compound affects cellular structure (stimulates cell renewal and collagen production). 

The conversion process, however, does not occur immediately upon use—it’s not magic. Several applications may be required before it’s transformed into retinoic acid. But for faster and more immediate results, you can incorporate light therapy into your skincare regime. 

Though light therapy on its own is powerful, when paired with retinol, the two are a perfect combination for flawless skin.

On its own, light therapy proves to be highly effective for treating texture, scars, acne, and overall skin rejuvenation. However, light therapy also deals with more severe skin issues such as eczema and vitiligo. So, why is it so effective?

The specific wavelengths of red light create a biochemical effect in our cells that serves to increase mitochondrial function. This improves the production of ATP (adenosine triphosphate) in the body.

We care about ATP because it's the source of energy for every cell in the body. Without it, we don't work at all. Without enough, we don't perform well.

The wavelengths vary between 630-880 nm and are used to treat the skin’s surface. The red therapy light penetrates the skin approximately 8-10 millimeters. Depending on which area of ​​the body the red light is used for, it can easily affect all layers of the skin, reaching the blood vessels, lymphatics, nerves, and hair follicles.

When red light therapy and retinol are paired together, they quicken cellular turnover and replacement. Initially, retinol and LED light therapy were considered inadvisable. But scientists have now discovered that retinol products paired with light therapy are advantageous—if done properly.

How to prepare for LED light therapy

When it comes to using retinol and LED light therapy, you want to make sure you do it properly. Naturally, aside from using light therapy and retinol, you should focus on eating clean, staying hydrated, getting adequate sleep, and reduce your exposure to sunlight. Now that we have that out of the way, here’s what you need to do.

  1. Cleanse your face thoroughly and pat it dry
  2. Use LED Light therapy mask for 10-15 minutes
  3. Apply your preferred retinol product
  4. Apply SPF

As mentioned before, it’s best to do this at night, not to let sunlight interfere with the efficiency of the process. 

Though there are many ways to treat our skin, ideally, you want a treatment that’s the least invasive and the most effective. Kaiyan's red light therapy devices are designed to treat a variety of skin conditions, helping you stay youthful. Our devices are MDA-certified and FDA-approved, ensuring that your treatment will be safe for your skin while providing you the best results.

Follow the Numbers: Light Therapy's Projected Market Revenue Surges

Follow the Numbers: Light Therapy's Projected Market Revenue Surges

Follow the numbers: light therapy's projected market revenue surges

Light therapy is used for many problems, such as skin conditions, eczema, vitiligo, acne, and rosacea. But it's also very popular as a skincare remedy for wrinkles, age spots, and collagen production.  While helping outwardly, it also works directly with mitochondria, the cells' powerhouse, improving our cell production and increasing cellular function. The non-invasive treatment is gaining popularity for its incredible benefits and cost-effectiveness. 

Light therapy also helps with our lack of vitamin D, and with the current world situation of quarantine and COVID-19, the lack has been more than evident. It helps with psychological conditions that have been rapidly increasing in the past few years, and the current situation only aids in the battle against winter blues and depression. This form of therapy increases melatonin levels and mood levels, helping with fatigue and sleep quality.

Since the market has been affected due to the pandemic, people have been turning to light therapy for its mental and physical benefits. The light therapy market is anticipated to reach 1,112.16 million dollars at a CAGR of 5.1%  by 2025, says Market Research Future (MRFR).

The American market is set to take the lead over in the next few years. Growing international curiosity for light therapy will also help the infrastructure, improve quality with more developers, stimulating substantial market growth. 

For winter blues, light therapy should experience a rise in growth by 5.1% till 2027. Due to less sunlight, light therapy proves as the ultimate fit for those in the Northern Hemisphere. The Asia Pacific light therapy market revenue surpassed USD 175 million in 2018, it is poised to expand at 5.7% CAGR through 2027. Their awareness of the growing patient pool and beauty conscious people fuel the demand for light therapy because of its amazing results in various skin conditions. 

Rising per capita income and the growing influence of social media are opening new avenues for the Asian Pacific market. The demand for light therapy is considerable among people in China and Japan. In addition, its popularity is also rising in developing nations owing to its advanced features and low cost. 

A segment of light therapy specializing in floor and desk lamps of the market was valued at more than 140 million dollars in 2018 and will witness a similar growth trend in the future. Similarly, large reflectors in the floor and desk lamps that diffuse bright light for accurate visualization are predicted to be in higher demand in the upcoming years.

Homecare settings portion had its share of revenue, counting more than 490 million dollars in 2018, and will exhibit a similar rising forecast in the upcoming timeline for light therapy. In 2020 these products held up to 60% of the market share. 

Demand for simplicity and more availability is what allows the rising demand for homecare handheld and user-friendly devices. It's predicted to grow gradually. Manufacturers will focus on developing light therapy devices that specifically solve health-related issues at home by providing easy access and improved patient management. 

North America light therapy market size crossed 350 million dollars in 2020 due to technological advancements paired with light therapy's growing use of light therapy.

Key developers in the U.S. have gained approvals from the FDA for new products, like Kaiyan Medical. With FDA-certified and MDA-approved devices, Kaiyan leads the light therapy devices industry and will continue to play a crucial role for the overall growth in the North American industry.


Red light Therapy and Hyperpigmentation

Red light Therapy and Hyperpigmentation

Skin conditions can majorly affect a person’s self-esteem. One of the most common issues: hyperpigmentation. We've all heard the term before, but what is it, exactly? 

Hyperpigmentation causes dark spots on the face, hands, and other visible parts of the body that have been exposed to the sun's rays. Not only can it cause insecurities, but it can be very difficult to hide as these spots form in different shapes and sizes, with colors ranging from light brown to black.

There are many types of hyperpigmentation, but the following are the most common:

Pigmentation spots are age spots that occur as a result of exposure to sunlight. This is why they mostly appear in parts of the body that are usually exposed, such as the face, hands and arms. These are usually small, darkened areas of skin.

Melasma or chloasma is often called a "pregnancy mask" because it affects 90% of pregnant women. It occurs as a consequence of hormonal influences during pregnancy and contraception. It causes dark spots of irregular shapes on the face or hands, which can be large in size.

Gradual hyperpigmentation occurs when a flat area of ​​discoloration remains after the skin injury has healed. It is a common occurrence among people who suffer from acne, and it can also be caused by cosmetic treatments such as dermabrasion, laser treatment, and chemical peels.

There are other factors that can darken parts of the skin - such as moles, scars, scars, sun or actinic keratosis, and skin cancer - but they’re not considered forms of hyperpigmentation. 

So, how does hyperpigmentation occur? It develops due to excessive production of melanin—a pigment that gives natural color to our skin, hair, and eyes—on certain parts of the skin. Many factors cause this overproduction, but the main ones can be related to sun exposure, genetic factors, age, hormonal influences, and injuries or inflammation of the skin. It can also be a symptom of certain diseases as well. 

Naturally, limiting the time you spend in the sun, wearing protective clothing, and using sunscreen with a high protection factor, both UVA and UVB, can help reduce the risk of hyperpigmentation and prevent worsening of existing dark spots.

Battling hyperpigmentation is possible in many ways, but red light therapy has proven to be the most effective form of treatment. It’s no secret that most of us lack vitamin D, at least in the Northern Hemisphere, yet light therapy has done wonders in vitamin D production. But red light therapy has shown to be helpful in even more ways than you could imagine. 

Red light therapy works by stimulating cells through red light. Mitochondria in the skin cells can absorb the light particles which emit through the red light, and this can help them produce more adenosine triphosphate (ATP), which is the energy source for all cells. By improving cellular energy, cells repair themselves quickly, returning the skin back to normal pigmentation levels. 

In turn, collagen levels increase, working to reduce other skin conditions, including rosacea. Elastin levels also increase, which helps fight against aging, giving the skin a lift and youthful glow. 

Though there are many ways to treat hyperpigmentation, ideally, you want a treatment that’s the least invasive and the most effective. Luna’s red light therapy devices are designed to treat a variety of skin conditions, including hyperpigmentation. Our devices are MDA-certified and FDA-approved, ensuring that your treatment will be safe for your skin while providing you the best results. 

Light Therapy: Detection and Treatment of Bovine Mastitis

Light Therapy: Detection and Treatment of Bovine Mastitis

Mastitis

“Mastitis” is one of the major challenges for the dairy industry worldwide, as this is the most common and costliest disease of dairy animals and contributes a substantial economic loss to dairy farmers. The subclinical stage of mastitis, i.e., Sub-clinical mastitis (SCM) in the dairy cow, is a matter of great concern for farmers as its incidence is more than clinical. In most animal farms, monitoring of sub-clinical and clinical mastitis (CM) is usually performed through an indirect test such as pH, electrical conductivity, somatic cell count (SCC), California mastitis test (CMT), culture test, and biomarker tests.

Apart from these, there is a need for new rapid and sensitive technology to identify udder infections at early stages. Early detection of mastitis using non-invasive technology needs the hour to reduce the dairy industry's economic loss and farmers. Skin surface temperature is a critical indicator of an organism's bio-physiological health status due to infection-induced inflammatory reactions, local blood circulation, metabolism, and skin surface temperature increases. Thus, monitoring the emitted heat from the udder can help in the early detection of mastitis. Moreover, Infrared thermography (IRT) using the susceptible thermal camera can monitor subtle skin surface temperature changes. IRT with the mobile-based application can further play an important role in managing dairy farms on various aspects.

IRT Imaging

SirWilliamHerschel,aBritishastronomer, in the year 1800, discovered Infrared radiation (IR) in sunlight. IR is electromagnetic radiation whose wavelength ranges from 700 nm (frequency 430 THz) to 1mm (300GHz). IR thermography works on principle proportional to their temperature, all objects using conduction, convection, and radiation, following Stefan-Boltzmann law, emits infrared radiation. Thus, Infrared thermography (IRT) can detect body surface temperature changes due to subtle blood flow changes.

Udder Health Status

Good udder health is one of the important conditions for clean milk production. The adequate steps help in the reduction of udder infections to contribute to clean milk production. Therefore, researchers are trying to monitor the milking process using IRT. Moreover, the udder thermogram can assess the milking hygiene, as the udder surface's cleanliness influences the measurement results, mostly surface temperature. The major concern of udder health is related to the occurrence of subclinical and clinical mastitis. Mastitis is the inflammation of the mammary gland causing physiological, biochemical, and pathological changes in udder parenchyma, result in alteration of milk quality.

Subclinical and Clinical Mastitis

IRT technology can detect clinical and subclinical mastitis. Subclinical mastitis is the major concern as it leads to more economic losses to the dairy farmers. In many cases, the cow's milk productivity and milk quality may reduce permanently. Early detection of sub-clinical mastitis can help diagnose and causative agents and help implement economic loss. The sensitivity and specificity technique used to detect subclinical mastitis using IRT is similar to that of the California mastitis test. An increase in temperature of more than 1oC was an indicator of mastitis and recommended IRT as a complementary tool in the early diagnosis of subclinical mastitis in Holstein and Brown Swiss cows.

Fig 1: Infrared thermogram of udder quarters for the normal and healthy quarter from a lateral view. RFQ: Right front quarter, RHQ: Right hind quarter LFQ: Left front quarter, LHQ: Left hindquarter.

Change in udder surface temperature and its measurement using Infrared thermography (IRT) in sub-clinical and clinical mastitis vary from the healthy quarter. Various researchers documented a wide range of differences. Therefore IRT can be used as a promising tool for the assessment of udder health. But, contradictory results are available in sub-clinical mastitis detection using RT, whereas mastitis can be detected efficiently using IRT.

Use of Light Therapy in the Treatment of Bovine Subclinical Mastitis

Methods: Forty cows with subclinical mastitis (n = 40) were divided into 4 groups (control, photodynamic therapy — PDT, light irradiation — LED, and photosensitizer — PS). The control group received no treatment. The PDT group received an application of 1.0 mL of 2.5% toluidine blue photosensitizer followed by LED irradiation at λ = 635 nm. The LED group was treated with LED irradiation alone, and the PS group received only 2.5% toluidine blue dye. LED irradiation was applied to the mammary gland utilizing an acrylic light guide coupled to the LED equipment. The PDT and LED groups were irradiated with 200 J/cm2 at three different positions inside the mammary gland. Milk samples were collected at 0 h, 12 h, 24 h after treatment for microbial identification and total bacterial count.

Results: The treatment of the PDT group showed a significant difference p < 0.05, characterizing this technique's efficiency with the reduction of the microorganisms Streptococcus dysgalactiae and coagulase-negative Staphylococcus.

Conclusion: Photodynamic therapy was effective when applied in vivo for subclinical bovine mastitis. There was no need to separate the animal from production.

Final Thoughts

Mastitis is one of the major concerns of the dairy industry, which leads to huge economic loss. In addition to established laboratory methods available for its diagnosis, there is a need to address in the light of early mastitis detection by some susceptible non-invasive techniques as well. Infrared thermography(IRT)using the susceptible thermal camera can be used as a non-invasive technique. Due to udder physiological changes during subclinical and clinical mastitis, IRT can measure the subtle change in udder temperature. Thus, infrared thermography may be a suitable tool for detecting mastic animals' early detection and dairy cattle screening. As there are some limitations adhered with IRT such as sunlight, moisture, dirt, weather conditions, etc. may influence the IRT's accuracy level, there is a need to explore IRT for diagnostic purposes subclinical and clinical mastitis under Indian climatic conditions.

References

Sinha, Ranjana. (2018). Infrared thermography as noninvasive technique for early detection of mastitis in dairy animals. 37. 10.18805/ajdfr.R-1746.

Moreira LH, de Souza JCP, de Lima CJ, Salgado MAC, Fernandes AB, Andreani DIK, Villaverde AB, Zângaro RA. Use of photodynamic therapy in the treatment of bovine subclinical mastitis. Photodiagnosis Photodyn Ther. 2018 Mar;21:246-251. doi: 10.1016/j.pdpdt.2017.12.009. Epub 2017 Dec 16. PMID: 29258951.

Ahmad, T., Bilal, M.Q., Ullah, S. and Muhammad, G. (2005). Effect of severity of mastitis on pH and specific gravity of buffalo milk.Pak J Agri Sci., 42: 3-4.

Alejandro, M., Romero, G., Sabater, J.M. and Diaz, J.R. (2014). Infrared thermography as a tool to determine teat tissue changes causedby machine milking in Murciano Granadina goats. Livest. Sci., 160: 178-185.

Annual Report, 2016-17, Department of Animal Husbandry Dairying and Fisheries, Ministry of Agriculture and Farmers welfare,Government of India, pp 61.

Bangar, Y.C., Singh B, Dohare, A.K. and Verma, M.R. (2015). A systematic review and meta-analysis of prevalence of subclinicalmastitis in dairy cows in India. Trop Anim Health Prod., 47: 291–297.


Light Therapy & C-sections

Light Therapy & C-sections

The experience of transformation from womanhood into motherhood is a privilege reserved exclusively for women. Pregnancy and childbirth are wonderful and remarkable moments of life. Giving birth to a child can be one of the most joyful experiences too. Naturally, expectant mothers spend a lot of time thinking about how they will give birth. Although most people believe that vaginal birth is the best way to deliver, sometimes a Caesarean section cannot be avoided. As well, labor pain is one of the most intense pains experienced by women, which leads to an increase in the number of women opting to undergo a cesarean delivery. Pharmacological and nonpharmacological analgesia methods are used to control labor pain. Epidural analgesia is the most commonly used pharmacological analgesia method. However, it may have side effects on the fetus and the mother. Light-emitting diode (LED) photobiomodulation is an effective and noninvasive alternative to pharmacological methods.

Caesarean section was introduced in clinical practice as a lifesaving procedure both for the mother and the baby. It is a surgical procedure in which the incision is made on the products of conception. Caesarean birth is often used as a prophylactic measure to alleviate the problems of birth, such as cephalo pelvic disproportion, failure to progress in labor or fetal distress. A major concern in maternal and child health nursing is the increasing number of caesarean birth being performed annually. In India, primary caesarean birth is about 30.2% of births. The majority of the states are within the WHO specified range of Caesarean section (5 to 15%). Among that, five states are above the range and 12 states below the specified range. Reports also say that the prevalence of Caesarean section is generally more in the southern states. After the baby is born via C-section, the result is a wound that must heal, and pain is common during this healing process.

Wound healing acceleration and pain management in women who underwent the cesarean surgery could help them to return to their normal functioning, especially to begin breastfeeding their newborns as one of the most important aspects of newborn care. Failure incomplete healing of the wound is one of the probable complications of caesarean section. Post caesarean wound infection due to delayed wound healing and pain are not only a leading cause of prolonged hospital stay but a major cause of the widespread aversion to caesarean delivery in developing countries. Management of those problems is essential to decrease infection, length of the hospital stay, pain, and help to return for normal function.

Mothers who undergo caesarean section should achieve immediate recovery than other surgical patients because of maternal and neonatal wellbeing. Several studies have investigated many approaches and protocols of wound healing and pain management in women undergoing caesarean section. Though different approaches have been introduced, these approaches are still inadequate and unsatisfactory in many patients. Thus it seems that postoperative management in this group of people is more challenging than other surgical patients. Infrared Rays have a therapeutic effect of increasing the blood supply and relieving the pain. This will increase the supply of oxygen and nutrient available to the tissues, accelerate the removal of the waste products, and bring about the resolution of inflammation. When the heat is mild, pain relief is probably due to the sedative effect on the superficial sensory nerve endings. It also helps to achieve muscular relaxation. Infrared rays also have a physiological effect on cutaneous vasodilation due to the liberation of chemical vasodilators, histamine, and similar substance, and a possible direct effects on the blood vessels. Stronger heating of infrared stimulates the superficial nerve endings. It has been noticed that pain is due to the accumulation of waste products, and because of stronger heating, the blood flow increases and removes that waste product, and the pain is relieved. In some cases, the relief of pain is probably associated with muscle relaxation. The muscle relaxes most readily when the tissue is warm. The relief of pain itself facilitates muscle relaxation. So the infrared radiation is considered a choice of Electro Therapy Modality for wound healing and pain among mothers who underwent caesarean.

References

Hopkins K (2000) Are Brazilian women really choosing to deliver by cesarean? Soc Sci Med 51:725–740

https://doi.org/10.1590%2F1806-9282.64.11.1045

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16192541

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=10594500

Light therapy and Obstetrics

Light therapy and Obstetrics

Being a new mother isn't a walk in the park. While a woman is pregnant, her body is carrying a fetus, and she’s experiencing hormonal changes in the body. This can take a toll on a woman's mental health. 

After pregnancy, aside from bringing a new life into the world, women are experiencing changes in their body after childbirth and starting a new lifestyle. While some women transition smoothly into motherhood, others experience mental health issues such as post-partum depression. 

What types of treatments are offered for women experiencing depression during and after pregnancy? Of course, there are various forms of medications and psychotherapy available; however, many women are skeptical about taking medications, and none seem to work effectively. 

Women experiencing depression during and after pregnancy can have their symptoms last between days, months, or even years. Depression during pregnancy include symptoms such as changes in energy level, mood, appetite, and libido. Post-partum depression symptoms can include mood swings, crying spells, difficulty sleeping, and anxiety. 

While there are various treatments and psychotherapy for post-partum disorders, there's one non-invasive, non-pharmacological, and high-effective treatment: red light therapy. 

What is Red Light Therapy?

Red light therapy uses red and near-infrared wavelengths to penetrate through the skin and increase mitochondrial function, stimulating blood flow, tissue oxygenation, and overall healing. Aside from the physical healing properties, it also aids in treating depression. 

A recent study published by Wirz-Justice in the Journal of Clinical Psychiatry shows that light therapy is a useful non-pharmacological treatment for women who suffer depression during pregnancy. The authors showed how light therapy treats seasonal affective disorder. They also reviewed two pilot studies of light therapy of antepartum depression and found that:

  • In an open trial with 3-5 weeks of light therapy for 60 minutes per day, depression ratings improved by 50%.
  • In a 5-week randomized, controlled trial for 60 minutes per day, depression ratings improved by 60% and 40%. 

The women included in this study were between 18-45 years of age, between 4 and 32 weeks of gestation, and were medically healthy. The results showed that light therapy reduced depression in comparison to placebos after 5 weeks. Through this study, it proved the benefits of light therapy for pregnant women with depression.

Light therapy could play a significant role in treating women with depression during and after pregnancy. 

Light therapy and Newborns

Aside from pregnancy depression, it's also believed that light therapy can improve conditions such as Jaundice, for babies. Bilirubin is a yellow substance that is a normal part of the red blood cells. The liver removes bilirubin and passes it through the bowels to leave the body. However, a baby's liver doesn't function as optimally as an adult, meaning they can struggle to pass bilirubin out of their bodies. This is when Jaundice occurs. 

While most cases of Jaundice naturally go away, some cases become serious. Jaundice can be caused by physiological issues, such as a premature liver, breastfeeding, and blood group incompatibility with the mother.

Light therapy has been shown to be highly effective in treating Jaundice. But why? Light therapy uses light to eliminate bilirubin in the blood. The baby's skin and blood absorb the light waves, transforming bilirubin into water-soluble isomers that can be eliminated without the liver.

For years, light therapy has been used in hospitals as a treatment for Jaundice; however, light therapy can be easily and more safely administered with today's technological advancement. 
Light therapy isn't something new, but mothers want to make sure what they're using will be safe for themselves and their babies. Today, we now have MDA-certified and FDA-approved light therapy devices, ensuring they're given a safe amount of light for mothers and their newborn children.

Source: Epperson CN, Terman M, Terman JS. Et al. Randomized clinical trial of bright light therapy for antepartum depression, preliminary findings. J Clin Psychiatry. 2004; 65(3):421-425.


Skincare Professionals: Keep Your Clients Coming Back With Light Therapy Treatments That Work

Skincare Professionals: Keep Your Clients Coming Back With Light Therapy Treatments That Work

If there’s one thing both women and men are trying to achieve, it’s turning back the hands of time. This explains why the anti-aging industry is projected to be worth $83.2 billion by 2027. With anti-aging on everyone’s mind, people are looking for the best ways to maintain their youthful glow and complexion. 

That said, many people interested in investing in anti-aging products are looking for non-invasive options that won’t require six weeks of post-surgical recovery time or monthly injections. While invasive options are anti-aging solutions, light therapy is an overlooked and underrated anti-aging therapy treatment in the skincare industry.

How Does Light Therapy Work? 

Light therapy uses varying wavelengths of light, emitting them onto the skin. The light penetrates through the layers of the skin, stimulating cellular regeneration and heals damaged tissues. While highly noted for its effectiveness for collagen production and tissue repair, it’s also ideal for reducing damage from acne, and eliminating wrinkles, inflammation, and age spots.  

While there are various light therapy devices on the market, some are standing out among the rest. Aduro's highly-rated 7+1 facial mask, eyewear, and handheld devices help combat skin imperfections and reduce aging signs. 

Aduro's light therapy uses different color and color combinations to target various skin conditions. In the 7+1 facial mask, each color offers a different treatment:

Red: increases collagen production for fuller and younger looking skin.

Blue: eliminates acne-casuing bacteria and reduces the appearance of acne.

Green: balances the skin’s complexion.

Yellow: reduces redness from inflammation and rosacea.

Orange: revitalizes the skin and adds glow.

Cyan: calms and soothes irritated skin.

Purple: promotes cell rejuvenation.

Infrared: amplifies desired results.

Users can either opt for one specific color or a combination of colors to tackle their skin’s needs.

“I originally purchased it to calm down my acne problem. And I am not getting any younger so all other lights, including wrinkle reducer will be a great help for my skin. The mask isn't heavy to wear. You can wear it while you are meditating, doing sit-down exercises and or other stuff.”

-Sandra G., verified buyer

As most people have more than one skin condition they’d like to treat, light therapy provides an all-in-one treatment for your clients. The 7+1 facial mask is intended for professional use, and gives equal coverage to the entire face. However, for clients looking for spot treatment on specific areas, handheld and eyewear devices can provide targeted treatment to areas with redness, inflammation, and discomfort.

“I purchased this for a recent flare of roceacea I got from using too many ordinary acids on my skin. I stripped the skin barrier and ended up with redness and red spots. I use the green, orange and blue and violet colour each morning for 1 minute each and notice skin evenness and definite reduction in roceacea I also use it after microneedling and it calm the red down.” 

- Sonia M., verified buyer

As more celebrities are turning to light therapy, people are becoming aware of its capabilities as a non-invasive treatment and are looking at light therapy as a solution to their skincare troubles. 

For clients looking for a relaxing facial experience with the added benefits of reducing their skincare imperfections, light therapy is the best solution. Kayian Medical produces medical-grade laser light devices for the skincare industry. All Kayian light therapy devices are MDA-certified and FDA-approved, ensuring your clients' high quality and results. Keep them coming back with skincare therapy that works.

Creating Your Custom LED Mask

Creating Your Custom LED Mask

When we talk about skincare, we usually don’t think about customizing skincare products. The options available on the market are produced for the masses rather than for the individual. Many people with multiple skin issues struggle to find skincare products that truly speaks to their needs. However, light therapy masks can be customized to fit the individual customer’s needs.

If you’re working in the skincare industry, light therapy devices are a revolutionary step forward, as you’ll be able to provide your customers with a unique light therapy mask.

But what’s the process of creating a custom light therapy mask? Here are the six steps you need to consider when developing a customized light therapy mask.

The Six Steps to Create Your Custom Led Mask

While going through these six steps, keep your vision of your mask in mind. This will help you answer some of the questions that are going to be asked below.

What’s your Goal?

It would help if you determined your product’s goals. Who are your clients? What are their unique skincare challenges? By understanding the basics, you’ll help your company determine the right strategy when creating your customized product. Light therapy masks can be made using different LED colors for a full range of beauty treatments, including acne reduction, anti-aging treatment, and collagen production.

What Material will you Use?

You need to select the right material. Facial masks can be made from a variety of materials, each with its own advantages and versatility. There are three types of light therapy masks to consider: flexible, semi-hard, and hard.

Flexible allows users to wear it while doing their daily activities. The patented air cushions and emitting SMD LEDs are ideal for indoor and daily skincare. Semi-hard masks are for professional use and have a hard shell, while soft inside. Hard masks are powerful facial masks for professional use and come with selectable light area options. They offer a deeper light therapy experience for clients.

What Kind of Shape will your Mask be in?

Light therapy masks don’t have to come in a traditional one-size-fits-all design. Depending on your target market, you’ll be able to choose where the placement for the cheeks, forehead, and eyes will be on the mask. This gives you more control over how the mask will fit on your client’s face.

What Areas Will your Mask Treat?

A traditional mask will cover the full face. However, you may not necessarily want your mask to provide full coverage. Consider the areas of the face you’d like to treat, as you may only want to create a mask for a specific target area.

Apply for a Prototype

You’ve answered all the questions above and have a vision of how you want your mask to look. From here, we help you take your vision and use our creativity and 14 years of experience in the industry to create a mask that fits your goals.

Launch & Listen

Now that the product is created, it’s time to launch it. Before the launch, we produce pre-pilot quantities that allow us to fine-tune our devices and ensure high-quality from start to finish.

Creating a light therapy facial mask is one thing, but you want to make sure it’s achieving your goals and making your customers happy. Once your product is launched, it’s crucial to monitor product performance and listen to customer feedback.

Naturally, you don’t want your light therapy mask to be like all the others on the market. Our masks are MDA-certified and FDA-approved light therapy devices, ensuring you medical-grade quality devices for your business.


 Red Light Therapy and Fertility

Red Light Therapy and Fertility

There is hardly a day in my various professional roles as a scientist, science watcher, or clinician without encountering new information or a new scenario that highlights the complexity of biology and biological systems. Such occurrences warrant careful evaluation and oftentimes lead to new management strategies or form the basis for further scientific investigation. This is inevitable as the knowledge base expands and our understanding of the variables potentially impacting our strategies and outcomes increases. We continually learn, re-learn and refine what we do and how we do it. The survival and performance of human spermatozoa in vitro is one evolving story that has far-reaching implications in numerous fields in addition to human reproduction.

Infertility is a problem that affects 15% of couples. Male reproductive issues account for one-third of infertility cases, with another third caused by combined male and female reproductive issues or unknown etiologies. Several strategies, including in vitro fertilization (IVF) techniques, are employed clinically to assist infertile couples in their quest for a successful pregnancy. Viable, strong, and normally motile sperm are critical to the success of IVF. It is well-known that spermatozoa in standard culture weaken and lose viability and motility at 12 hours and that by 42 hours, only about 52% remain viable. Fewer strong and motile sperm reduce the probability of a successful IVF cycle. Protocols that could improve viability and performance of sperm in vitro would be of great interest to clinicians and patients alike.

At low concentrations, reactive oxygen species (ROS) act as second messengers that regulate increases in cyclic adenosine monophosphate (cAMP), the activation of protein kinase A (PKA), the phosphorylation of PKA substrates of the arginine-X-X-(serine/threonine) motif, the phosphorylation of extracellular signal-regulated kinase (ERK) and mitogen-activated protein kinase (MEK) proteins and the threonine-glutamate tyrosine motif, as well as fibrous sheath protein tyrosine phosphorylation. These functions are involved in sperm capacitation, acrosome reaction, and oocyte fertilization.

Sperm plasma membranes contain large quantities of polyunsaturated fatty acids (PUFA), whereas their cytoplasm contains low concentrations of enzymes that scavenge ROS. High concentrations of ROS overwhelm the endogenous antioxidant defenses of gametes, causing multiple derangements. High concentrations of ROS cause peroxidative damage to plasma membrane PUFA, DNA damage, the depletion of mitochondrial adenosine triphosphate (ATP), apoptosis, and the loss of sperm motility.

ROS are generally short-lived in vivo due to several antioxidant pathways and compounds at play. However, they are known to accumulate in both oocytes, and spermatozoa cultures, both of which can generate ROS in small quantities as required for the fertilization process.

Sommer et al. posited that polystyrene softens in the presence of aqueous solutions. This creates conditions that would cause a nanoscopic layer of ROS to become established in plastic Petri dishes in common laboratory use. This hypothesis was confirmed by evaluating the cell performance of ROS-sensitive cell lines cultured in both polystyrene and ultrasmooth nanodiamond coated Petri dishes. The cell lines tested included mouse P19 embryonal carcinoma cells, murine-derived L929 cells, and HeLa cells derived from human cervical cancer. The nanomechanical softening was demonstrated in subsequent work by this group and others.

The use of nanodiamond surface coating of culture dishes was based on the knowledge that this material is both chemically and biologically inert, with a capacity to bind a nanoscopic layer of water to its surface. Sommer demonstrated that the material and this nanolayer were, for practical purposes, ROS-free. They subsequently reported that culturing human sperm cells in diamond-coated Petri dishes rather than the polystyrene dishes typically used for IVF resulted in approximately 20% greater cell survival at 42 hours in the nanodiamond coated cultures. This confirmed that the culture dishes themselves play a role in sperm survival in vitro. That accumulation of ROS on the polystyrene surface is a causative factor in decreasing viability over time.

Sommer et al. went further exposed the cultured spermatozoa to red light at 670 nm. Light at this wavelength is known to be absorbed by cytochrome C oxidase and other molecules, stimulating ATP synthesis and affecting ROS production, among numerous other activities at the cellular, tissue, and whole organism level. However, the caveat is that the light dose and dose rate are important and that all cells and tissues are not equally responsive to photoirradiation.

They found that the number of sperm cells demonstrating grade A motility was enhanced by nearly 300% after 1-hour contact with the nanodiamond coated quartz Petri dishes compared to the counts obtained for spermatozoa in the polystyrene Petri dishes. They also observed that sperm motility was significantly different after contact with polystyrene and nanodiamond when longer periods of photoirradiation were applied. A 3× higher light dose was detrimental to the motility of sperm in polystyrene plate cultures, resulting in a reduction of counts to those of the control group at 45 and 60 minutes post-exposure. The same light dose delivered to spermatozoa cultured in nanodiamond dishes produced a dramatic increase in progressive motility.

This series of experiments demonstrates that diamond Petri dishes and NIR light delivered at specific parameters energize sperm cells in a complementary fashion, whereas polystyrene Petri dishes exhaust them. The red light counteracts internal oxidative stress due to ROS production in mitochondria by suppressing ROS accumulation and enhancing ATP synthesis. Simultaneously, the diamond substrate prevents the build-up of a layer of interfacial ROS between the sperm cell and surface of the culture plate.

Photobiomodulation (PBM) describes the ability to stimulate or inhibit cellular functions by using light at specific wavelengths, intensities, and dosing regimens. The classically described PBM treatment window is between 600 and 1,200 nm. Light in this portion of the spectrum readily penetrates skin and tissues via the so-called optical window. Light is absorbed by various structures and molecules, primarily molecules that are instrumental in energy production and oxygen delivery.

PBM effects depend upon timing, site of treatment, and treatment parameters (dose). PBM has shown efficacy clinically in accelerating wound healing, reducing pain and inflammation, and benefiting other applications, including the treatment of neurologic disorders and injuries.

The mechanistic basis for the outcomes observed after using photobiomodulation therapy (PBMT) results from the upregulation of intracellular metabolism by increasing ATP production, augmenting other metabolic pathways, and reducing ROS and other free radicals production.

The interaction of photons with cells and cellular structures is a necessary condition for PBM. We have learned that all cells and tissues don’t respond to PBM and that one size does not fit all when determining the dose or treatment course. Different photobiomodulation effects have been described depending upon the specific cell lines and species being investigated. Our laboratory demonstrated that cell proliferation and metabolism in vitro could be influenced by varying the dose frequency or treatment interval of the PBMT (17). We have also demonstrated this same phenomenon regarding wound healing in a murine pressure ulcer model. These investigations underscore the concept that a unique dose frequency combination exists for tissues and cell lines. This specific treatment paradigm must be determined to optimize outcomes and maximally stimulate cellular metabolism and proliferation. Our work also demonstrated that using other treatment strategies will paradoxically cause big inhibition, despite delivering the same total energy.

It is becoming increasingly apparent that biological systems are quite complex. They contain numerous pathways poised to work in concert with, or in opposition to, depending upon the organism's current needs. We are beginning to understand that these systems utilize several common denominator substances and reactions and that these can be manipulated using several forces, including light.

As scientists and clinicians, we apply what we have gleaned from the laboratory to solve clinical problems and to form the basis for further investigations. We often base these decisions on results obtained using various cell, tissue, and whole animal models, presuming that these models are translatable to our specific applications. Careful in vitro studies can be powerful tools that guide the design of whole animal and human trials. They facilitate the efficient and reproducible screening of a matrix of treatment parameters. We presume that the animal models we develop accurately reflect the actual biology and physiology found in nature.

Abolins et al. recently demonstrated that laboratory and wild mice's serological, cellular, and functional immune responses differ. Wild-type mice have a population of highly activated myeloid cells that are not found in their laboratory counterparts. The point here is that laboratory models and laboratory conditions, in all likelihood, do not entirely replicate nature.

Sommers’ work demonstrates that PBM with a red light at 670 nm improves spermatic function and viability in vitro. This effect augments the beneficial effects of using nanodiamond coated culture dishes. It also demonstrates that various cell lines respond differently to similar manipulations. This body of work also highlights the fact that the ubiquitous polystyrene culture dish can have a deleterious effect on outcomes. We would do well to recognize that the seemingly innocuous may not be and that we should remain cautious as we interpret experimental results and attempt to apply them. Every detail matters, even the seemingly mundane.

References

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Preparing your Skin for Light Therapy

Preparing your Skin for Light Therapy

Can I Use Serum With LED Mask?

It is a question that many people have asked — Can I use the serum with LED light therapy?

Our skin is exposed to harsh environmental factors such as sun, wind, cold, and dust daily. These factors tend to attack our immune system causing it to weaken over time.

When this happens, it allows harmful viruses and bacteria to attack our body, leading to acne breakouts and other skin issues such as dark spots and wrinkles. Acne creams are one way of reducing the symptoms associated with this skin condition. However, these can be irritating to your skin, resulting in unwanted side effects such as redness, irritation, and dryness.

The same can also be said for light therapy, which can have its own side effects. Side effects of LED light therapy include itching, burning, and pain. In fact, most users had reported experiencing these side effects when they first started using LED technology. If you were to use any acne medication type, whether prescribed by your doctor or over the counter, the results would depend largely on the person using the medication.

For example, it could take anything from a few days to a few weeks for acne to clear up. Another point to remember is that while certain medications do show better results for some people, they may not work for you at all.

This is because everyone has different skin types, responds differently to treatments, and requires different times to clear away acne completely.

Some people have found success in using LED therapy with a variety of skin creams. However, there is a downside to using this method. LED light therapy does not help remove excess dead skin cells, as some acne medications do. This means that the acne cream will just be left in place and continue to produce side effects for all patients. Besides, side effects can be more severe than a single acne medication dose when used over a long time when used over a long time.

Before you try to use a serum with an LED mask, you should consult with a dermatologist who can advise you on whether or not LED light therapy is right for you. LED light therapy is safe when administered by a certified medical professional. It can be used safely, even if you have sensitive skin, as long as you choose your doctors wisely. Before any treatment is begun, the medical professional will test your skin to determine what type of acne you have. Testing will determine whether your skin is allergic to any light-emitting diodes in the device used.

The last question to answer is, “How effective is Acne treatment with LED Light?” To answer this question, you will need to look at the results you get from the treatment. If you see immediate results after the treatment, it will likely react to the device's light and not the treatment itself.

However, if you don’t see good results after a month of continuous treatment, it is important to determine why the treatment is not working. It may be that you are allergic to any of the ingredients in the product, or it may be that your skin is not receptive to the treatment.

Hydrated Face For LED Mask Results

The serum is good for hydrated face for LED Mask. It can hydrate the skin by absorbing moisture, providing a slight lift to the skin, and removing any oil or makeup that you are using. The serum also contains vitamins and antioxidants that will help fight against free radicals in your body. Free radicals are harmful agents that have been linked with causing cancer.

By fighting against these harmful agents, Serum is good for hydrated face for LED Mask. People who have used Serum have claimed that the hydrated face and LED Mask work very well together. I have also used Serum on my skin, and I must say that the results were really amazing. In fact, I would go on to say that Serum is so good for hydrated face for LED Mask that I will be using it every single night before bed.

If you don’t have much experience making skin look hydrated, this is the forum for you. Let us first examine the ingredient list of Serum.

This product's main ingredients are Hyaluronic Acid, Vitamin C, Retinol A, Alpha Hydroxy Acids, Vitamin E, DMAE, Peptides, and Glycerin, Ferulic Acid, Aloe Vera.

  • AHA kills the bacteria causing acne and helps to get rid of blackheads.
  • Sodium Laureth Sulfate helps in cleaning the skin by getting rid of dead skin cells and excess oil.
  • Salicylic Acid gets rid of pimples and acne scars, and Glycolic Acid is good in treating acne scars.

All of these ingredients are perfectly good for your hydrated face for LED Mask.

  • Now let us move on to how does Serum works to get rid of the facial puffiness.
  • When you are applying Serum on your hydrated face for LED Mask, you are putting on a layer of serum to the surface of your face.
  • As the serum gets applied, it works its way down into your skin and starts working as a moisturizer.
  • This is why this particular product is top-rated as it works as a good moisturizer without over-drying the skin.
How to Prepare Your Skin For a Red Light Therapy Session?

There are different methods used to prepare your skin, but essentially they all work in the same way: removing all the oil and dirt from the skin and then cleaning it. When I talk about cleansing, I’m talking about daily skincare maintenance products. If you want to know how to prepare your skin for a red light therapy session, this is the part that you need to read.

Most people have no idea how their skin looks like, so when they go into the doctor’s office and they've asked if they’ve had a photodynamic therapy or a laser treatment, they’re not aware of what treatment they might have received.

  • The skin absorbs red light from the sun, and in return, it produces negative ions.
  • These are similar to the particles produced by an activated oxygen generator (you know those things at the gym).
  • During photodynamic therapy, the skin cells absorb the energy from the lasers' red light, which causes the release of more negative ions, which then penetrate deeper into the skin.
  • They’re working like the “batteries” on your car — they give the batteries extra power and allow the car to run much longer.
  • If you want to learn how to prepare your skin for a red light therapy session, you must remove all the grime from your face and neck before the session.
  • Cleansing is one of the most important steps to remember in preparation.
How to Prepare Your Skin for Red Light Therapy Session by Using Non-Dry Cleanser

You might need more than just a good cleanser when trying to prepare your skin for red light therapy. Your cleanser is your friend when you are trying to remove all the dirt and excess oil from your face, but what if your cleanser is too harsh on your skin? If you have dry skin, using a cleanser containing too harsh ingredients may cause dryness, making it harder for you to remove those excess oils from your face.

When you prepare your skin for red light therapy session using the non-drying cleanser, make sure that you would be using a toner with antioxidants and anti-inflammatory ingredients to increase the collagen level the skin.

This will help keep your skin healthy and younger-looking.

Caution: Lotion and Moisturizers For LED Masks Are Not Recommended

The use of moisturizers and lotions is not recommended for LED masks because it will damage your skin. There are also cases wherein people who used such products ended up suffering from adverse effects.

The ingredients in these products may be too strong for the skin to be able to absorb.

You can prevent this by using only non-comedogenic lotions and moisturizers for LED masks.

  • This way, the product is less likely to irritate your skin. In addition to that, you can also use other types of products designed for sensitive or dry skins to use on your face during the event's preparation.
  • However, there are cases wherein people who have been using such moisturizers and lotions as part of their LED facial make-up mask ended up suffering from adverse effects.
  • In these cases, the products were not properly applied to the skin, and the amount that was applied was also insufficient.
  • Because the skin did not get sufficient moisture, the cells underneath the skin's surface could not repair themselves properly.
  • This will result in damaged skin, which will cause more breakouts than before.

Aside from lotion and moisturizers, it would help if you also stayed away from mineral oil, alcohol, and preservatives. These ingredients are not good for your skin, as they can cause dryness and irritation. It would help if you also stayed away from using creams and lotions with fragrance, which can only irritate your skin even more. Instead, look for serums.

If you want to have a glowing complexion without enduring any adverse effects, use a good quality face serum.

Prepare Your Skin For Red Light Therapy by Removing Sunscreen

You probably have heard that it is unsafe to use the sun’s UV rays at home, especially if you use a tanning lotion or a self-tanning lotion. But did you know that it is also not safe to use self-tanning products like tan accelerators and sunless tanning pills to prepare your skin for red light therapy sessions?

This defeats the purpose of using red light therapy, and you must remove sunscreen so that your face and skin are completely ready to receive the red light therapy. This is because self-tanning products contain ingredients that can affect the skin in adverse ways and block the beneficial deep penetrating infrared wavelength from 650nm to 850nm.

How to Prepare Your Skin For Red Light Therapy by Removing Makeup

If you have chosen to have laser acne treatment and you are wondering how to prepare your skin for the red light therapy, you will want to take a moment to learn how red light therapy works before getting started.

Before your session begins, you will be given a short amount of time to get ready for the procedure. This is because your skin needs to be very clean and free of any makeup. Your skin needs to be completely dry before the procedure can begin.

If there is any moisturizer on your skin when you arrive for your appointment, you will have to remove it before your treatment.

Your doctor will ask you several questions about your skin during your appointment, including what type of skin you have and whether or not you have any allergies. During this time, they will also determine if you are a good candidate for the procedure. If you are cleared for the procedure, your skin will be exposed to an intense red light level. This is one of the most effective ways to get rid of acne, and it can also help prevent scars and aging from occurring on your face.

The amount of time that it takes to get your skin prepared for red light therapy varies. In most cases, it is normal to have it take from fifteen to thirty minutes to prepare your skin for the procedure. You may have to remove any makeup at this time as well.

How to Prepare Your Skin For Red Light Therapy by Exfoliating?

When a patient is getting a therapy session done, they will be required to go to the spa or beauty clinic to be given a facial.

A therapist will then start by cleaning the face thoroughly. After the initial cleaning process, the therapist will apply a chemical that will help exfoliate the skin.

This process can irritate the skin, so it is important to prepare your skin before undergoing this procedure. Some common preparations that people use include salicylic acid, alpha hydroxy acid, retinoids, glycolic acid, and other peel-type products.

The exfoliating procedure aims to help the skin cells shed off dead skin cells and replace them with new cells.

This is why it is important to remove all traces of dead skin cells from your face before undergoing the procedure.

It may seem odd at first, but if you want to get the best results from the procedure, you need to gently exfoliate your skin.

Prepare Your Skin For Red Light Therapy With Moisturizers

When you prepare your skin for red light therapy, you are basically preparing to expose the blue spectrum laser's high intensity and the eventual dry out of the epidermis. The skin must be prepared using a good cream containing Reductase or Salicylic Acid, or by exfoliating the skin using a scrub.

After the procedure, you will need to have topical products applied to your skin to prevent the skin from cracking and peeling. This will also help improve your appearance and prevent future scarring. Removing moisturizers before the therapy can be helpful. This is because the skin’s cells will still be in a dormant state when you receive the treatment; therefore, your skin is not at risk for the dryness associated with moisturizers.

This will also improve your skin's look, especially for those who have undergone this procedure many times. However, you must be youthful if e to remove moisturizers in preparation for the session, as some creams may cause excessive dryness and irritation. Once you are prepared for the session, you can expect the doctor to start the red light therapy by generating a small amount of blue light on your skin's top layer.

The light then travels through the skin, reaching the deepest layers where most of the damage occurs. When the blue light is emitted, it is believed that the cells below the surface of the skin begin to absorb the red light, helping to repair the skin. The increased circulation and nutrient absorption help to rejuvenate your skin, leaving it looking younger and healthier than ever before.


Celebs are Loving Red Light Therapy

Celebs are Loving Red Light Therapy

When it comes to anti-aging remedies, celebrities are at the forefront of all the latest treatments. For years, Hollywood’s elite have opted for chemically-induced anti-aging treatments, like botox and chemical facial peels. But it looks like Hollywood is stepping away from harsh treatments, particularly with the prominence of clean and holistic beauty trends in recent years. Now, many celebrities have decided to avoid the needles and knives, opting for natural alternatives, instead. 

To prepare for red carpet events, celebrities are flocking to red light therapy for natural, non-invasive anti-aging treatments. Kourtney Kardashian, true to Kardashian form, was relatively early to the red light therapy scene in 2016, when she posted a photo of herself in wearing a red-light mask, touting the many anti-aging benefits of the treatment. Since then, other celebrities such as Kelly Rowland, Emma Stone, and Chrissy Teigen have openly shared their positive experiences using red and blue light facial therapy treatment. 

Some actresses love red light therapy so much, they have their own equipment set-up in their homes. Back in 2018, Olivia Munn told US, "I have my own facial set up, I've got the professional-grade products and machines...But one of the best things is the red and blue light mask."

Red light therapy works by increasing blood flow and oxygen, feeding the cells the necessary energy they need to speed up the cellular process. This process helps decrease inflammation and enhance collagen production, which reduces the appearance of fine lines and wrinkles for tighter and supple skin. 

Jewelry designer and reality T.V. star Kristin Cavallari told US that she keeps away from Botox, but shared that

"I use red light therapy twice a week to prevent lines and wrinkles."

But red light therapy isn’t only for wrinkles and fine lines. Celebrities are expanding the use of red light therapy and using it for their entire bodies. Why? Well, house-friendly red light devices help treat inflammation, joint pain, and muscle soreness. 

Ara Suppiah, M.D., an assistant professor at the University of Central Florida Medical School and an emergency and sports medicine physician, told Us Weekly that “increased energy within a muscle cell allows it to contract harder and repair itself after training.” Since red light increases cell energy, it subsequently helps organs, joints, and muscles to repair themselves and function optimally. 

The list of celebrities who swear by red light therapy continues to grow by the day. Joan Smalls and Bella Hadid visit celeb aesthetician Joanna Czech, who is well-known for using her light treatments on her clients. Riverdale’s Lili Reinhart and Camila Mendes also posted photos from Joanna Vargas’ red light bed.

So, it’s clear that the verdict is in: celebrities are loving red light therapy and the multiple external and internal benefits that come along with it. But do you need to undergo expensive treatments to get a taste of the benefits? Nope! You don’t need to be a celebrity status to enjoy the benefits of red light therapy - even in the comfort of your home. 

Luckily, red light therapy is now available for in-home treatment with Lunas’ FDA and MDA-approved red light therapy devices. By having a red light therapy device in your home, we can all attain our own red-carpet glow without the celebrity price tag.

Photo Credit: By Tinseltown - Shutterstock

How to Integrate Light Therapy into your Lifestyle

How to Integrate Light Therapy into your Lifestyle

Our lives are busier than ever, and even though red light therapy sounds like something that could significantly benefit you, we know you might be thinking: “when will I have time for red light therapy?” 

Part of the beauty of red light therapy is that you don't need to change your current routine or lifestyle to enjoy its benefits: if you're someone whose day is busy in front of a desk, you can turn the device on while you work; or if you have easy-going mornings but hectic afternoons, you can enjoy your morning coffee while using our red light therapy device. Or, you can turn on the panel while you’re unwinding with a movie in the evenings –– the options are endless.  

Red light therapy treatment isn’t supposed to take over your day and cause an inconvenience. With an at-home red light therapy device, you make the rules. 

That said, you may be wondering what’s the best time of day to use our red light therapy devices. Well, there are a couple of ways you can integrate red light therapy into your lifestyle. 

There are three main parts of the day: morning, midday, and evening. Though you’re able to use red light therapy any time of the day, some parts of the day can be more effective than others, particularly given your personal health and wellness needs. 

If you’re someone who’s suffering from a sleep disorder, then you may want to focus on using red light therapy during the mornings and evenings. For sleep conditions, using red light therapy around sunrise or sunset are the best times of the day. Why is that? 

It has to do with our biological circadian rhythm, which is the natural internal process that helps regulate your sleep cycle within a 24-hour day. To optimize your circadian rhythm and improve your sleep cycle, you need to sync with your natural sleep rhythm. By doing so, you reduce sleep inertia, insomnia, and other sleep disorders. 

When regulating your circadian cycle, your body releases a hormone called melatonin. This particular hormone is the highest in the blood at night and optimal for helping you fall asleep. When using red light therapy at night, it can help you enhance your natural melatonin production

When using red light therapy in the morning, exposure to light helps stop melatonin production, giving your body a natural energy boost. So, either time of the day––morning or night––can be an incredible time to help your body reset its circadian rhythm. 

You don’t need to schedule off your morning for red light therapy treatment. While you’re eating your breakfast or going through your emails, you simply turn on your red light therapy device and enjoy 10 to 15 minutes of treatment. 

Or, in the evenings when you’re cozied up on the course, washing the dishes, or sitting in bed with a book, turn on your red light therapy panel to help regulate your sleep cycle, mood, and overall health. 

If you can’t manage to use red light therapy in the morning or evening, you can always have a treatment in the afternoon, as well. If you’re dealing with a sleep disorder or seasonal depression, we recommend morning or evening treatment. However, midday treatment will also provide you with a load of benefits, including collagen production, decreasing symptoms of depression, improving sleep disorders, and non-seasonal Bipolar depressive episodes. 

Whatever the condition may be, whether it's a sleeping disorder, skin condition, or depression, Lunas red light therapy devices promote cellular healing from the inside out. What’s important is you find the time of the day that best suits your body’s needs. Everyone is different, so it’s important to find out what works for you and your unique routine and lifestyle.

Red and Blue LED Light on Milk Yield in Dairy Cows

Red and Blue LED Light on Milk Yield in Dairy Cows

Ruminant nutritionists formulate rations balanced according to the nutritional needs for the ruminant at a specific production level. The assumption being that the cows will eat everything they offered. However, cattle can select their feed, as they put together feed using their tongue and lips. Sorting has been studied most in cows al mixed ration (TMR) since it is often is oftenibitum, allowing cows to pick the feed particles they prefer and still reach the total dry matter (DM) they want. The TMR reports show that the most likely sorting is in favor of the short particles (mostly concentrate) and against the long particles (forages). Therefore, the feeding behavior of the cow modulates the amount of feed she eats, the nutrients she gets, rumen health, and ultimately her milk production.

Several methods have been used to try and reduce feed sorting in dairy cows. Recently, a long day photoperiod has been reported that could lower feed sorting against long particles. Today, Kaiyan provides advanced LED light equipment that is available for commercial use. The LED wavelength can be adjusted to the desired output.

Blue and red wavelength light has attracted interest in dairy barns. The cow eye is not sensitive to a red light, and therefore red light has been suggested as an option for illumination when people need to work with the animals during a time of the day when the cows have night. In humans, blue light is known to cause a carryover effect with increased activity after the light is turned off. If cows respond similarly to blue light, it may be interesting to include blue light in the dairy barns in the late afternoon or evening to stimulate activity during the night. This is of particular interest for automatic milking systems since they require cow activity around the clock. Solutions for dairy barns that include periods of the day with more red or blue LED light are already available on the market, as we now have fixtures of white LED light.

Eating Behavior of Dairy Cows

Encouraging DMI to promote milk production is one of the primary objectives for dairy farmers. The daily eating time, selection, number of meals per day, duration, and number of eating occasions per day are important aspects of feeding behavior.

Factors that Influence Eating Behavior

The environment, age of cattle, teeth condition, feed composition, and processing influence eating behavior. Just like grazing cattle, group-housed cows synchronize their behavior, including eating when kept indoors. The eating behavior of cows is controlled by social interactions, management practices, the environment, and health. Long ago, dairy cows were thought to be crepuscular eaters, motivated by sunrise and sunset timing to go for grazing. However, studies reported that fresh feed delivery timing had more influence on the feeding behavior of dairy cows kept indoors than the time of day. Also, studies found that daily eating time distribution changed following an increase in feed delivery frequency in group-housed dairy cows. The first hour and a half after fresh feed delivery is the period of peak eating activity. Little effect on cow behavior was observed when feed push-ups were done while still some feed in the trough. The feed trough design also affects feeding behavior as cows prefer eating from a feed trough that allows their head to be in a natural grazing position than having their head in an elevated position.

Types of Lights Used in Dairy and the Newly Available Light Sources

Common light sources used in dairy facilities are fluorescent and metal halide lights. During the last few years, LED lights have also become available for animal housing. This is not a new technology; LED light has been used in plant growth research since the mid-1980s but has been costly; hence limited to research only. However, 19 the Haitz’ Law as projected by Steigerwald et al., has come to action, that every decade their cost will decrease by 10 whereas their performance advances by a factor of 20. Now they have become affordable and advanced white LED lights thereby increasing their potential use in animal houses commercially

Advantages of LED Lights

It is possible to adjust the light intensity and spectral composition of LED lights mimicking that of natural day sunrise and sunset, making it possible to control color combinations, e.g., green, blue, and red. A LED light's lifespan is longer than that of fluorescent lights, around 100 000h compared to 8000 h. Furthermore, LEDs thermal output is low, saving energy, containing no mercury, efficient photoelectric conversion, and easy-to-contact to digital control systems making photoperiod management easy, for example, in dairy barns. Due to their long life span, they can decrease production costs as they do not need regular replacement and cuts off labor costs and the often-high risk work task of replacing lights since most barns have very high ceilings. The white LEDs produce light in the wavelength that cows can detect better, with peaks of emission around 460nm and 550.

In one study, ten multiparous pregnant Swedish Red cows in post-peak lactation were used. Cows were housed in a tie-stall barn. They were subjected to a 33-day red or blue LED light treatment during a long day photoperiod with 16 hours day and 8 hours night. Cows were fed silage and concentrate separately. Silage was fed three times a day, ensuring ad libitum intake with 5–10% orts. The concentrate was fed four times per day. Samples of silage were collected thrice a day, and individual orts were collected at the end of the day and the night. Data for eating behavior and milk yield were collected five days before and five days after the treatment period. Eating behavior was determined using the difference in the distribution of fractions of different straw lengths in the silage fed and orts during daytime and night time. A 2-screen Penn State Particle Separator (PSPS) (19mm and 8mm) with a solid bottom pan was used to determine the distribution of large, medium, and short silage fractions. Treatments did not affect total DMI. Overall, cows sorted for the large fractions against the medium and short fractions. During the LED period, there was a difference (P<0.001) in sorting between Red and Blue cows during the daytime. Cows on the Red LED light are sorted for the short fractions during the daytime. Blue cows showed different sorting (P<0.05) during day and night. Their sorting for the large fractions was more pronounced during daytime than night. Milk yield did not change during the trial and did not differ between the Red and Blue groups. In conclusion, sorting activity was greater during the daytime in the LED period, which could have been influenced by the LED light. Interestingly cows seem to have better vision in red than blue LED light. Furthermore, it also possible that the LED light maintains milk yield since no change was observed during the four-week trial in post-peak lactation.

Light Therapy - An Alternative to Botox and Fillers?

Light Therapy - An Alternative to Botox and Fillers?

It’s safe to say that most people would prefer to slow down the physical signs of aging, particularly on their faces – and the proof is in the numbers. In 2018, the global anti-aging market was estimated to be worth around $50.2 billion U.S. dollars. Now that's a lot of skin cream and Botox. And those numbers are only increasing: by 2027, the anti-aging product industry is projected to be worth $83.2 billion U.S. dollars. 

Of course, a large portion of sales are going to anti-aging creams and serums; however, there's been an increase in soft-tissues cosmetic procedures like Botox and filler treatments. A report from the American Society of Plastic Surgeons from 2018 reported around 7.4 million injections of botulinum toxin (Botox) and 2.6 million dermal filler injections we used that year. 

In America alone, Botox and fillers ranked the second most popular, minimally-invasive cosmetic procedures. But why are they so popular? Due to their invasiveness, they're more effective than anti-aging creams. However, that comes at a potentially risky and painful price. 

Botox's side effects include bruising and swelling at the injection site, fever, chills, and headaches. Some side effects are specific to the area of injection and include drooping eyelids, excessive tearing, and uneven eyebrows and other facial muscles. More importantly, research on the long-term side effects of Botox and fillers is limited. There are immediate results, yes; however, there's an unclear understanding of what Botox and fillers do to the body in the long-term.

Aside from health concerns, Botox and fillers can quickly add up financially, too. The most common Botox and filler treatments cost hundreds of dollars per session. Women and men around the world are risking their health and money to look youthful, but what they don't realize is there's non-invasive alternatives to these procedures, including light therapy. 

Aside from light therapy’s plethora of benefits for the human body, it is an amazing anti-aging alternative for those looking for non-invasive and natural anti-aging results. Light therapy reduces fine lines and wrinkles, but goes beyond just skin deep. 

While Botox and fillers work to cover the symptoms of aging skin, light therapy solves the problem at a cellular level. As we age, our body’s collagen production decreases, leaving our skin less plump and full. However, through light therapy, you’re actually stimulating collagen production beneath the skin to receive natural and similar results to Botox and fillers. 

Light therapy works by delivering wavelengths of red and near-infrared light to our skin and cells. Red light enhances our cellular function, stimulating the cell's mitochondria to produce ATP (adenosine triphosphate) energy. This boost of cell energy promotes collagen and elastin production, bringing the plumpness back into your skin. 

A 2014 study found that users of red light therapy experienced significantly improved skin complexion and increased collagen. Angela Lamb, M.D. and associate professor of the Department of Dermatology at the Icahn School of Medicine at Mount Sinai Hospital in New York City, stated that "Science shows that red light therapy protects existing collagen and boosts new production. Plus, it helps with texture, tone, pore size, and wrinkles."

However, there are more benefits to red light therapy than natural collagen production. Light therapy also aids in diminishing fine lines and wrinkles, reduces scarring, fights acne, treats inflammation, and aids in muscle recovery.

The proof is in the research, and study after study has shown the same results: red light therapy works for anti-aging. Rhonda Klein, M.D., a board-certified dermatologist in Connecticut, said that “Realistically, you can expect RLT to improve your skin’s tone and texture. We know that it soothes inflammation, improves mild acne, and proactively treats fine lines and wrinkles, in addition to other benefits.”

Lunas’ red light therapy devices are both MDA and FDA-approved, assuring you receive the highest quality of red light treatments available on the market, which is essential in receiving the best, most efficacious results.

Light Therapy & the Five Steps of the Creative Process

Light Therapy & the Five Steps of the Creative Process

The creative process has traditionally been broken down into the following five stages: preparation, incubation, insight, evaluation, and elaboration. These terms themselves likely won’t do much for your creative spirit, but below, we’ve broken each down to help you understand and relate to them more easily.

Preparation

Preparation sounds a bit like you’re studying for an excruciating exam you’ve got to take in the morning, but this feel-good phase is where your best ideas are born.

Think of it as if you’re taking an exciting journey into the creative space that appeals most to you. In today’s modern world, that might look like exploring a specific hashtag like — #lighttherapy, #redlight, #redlighttherapuy, etc. It could also look like deep-diving into autobiographies of artists who inspire you, perusing artist websites and their virtual galleries, watching documentary films on the topic, listening to music, reading through poetry, or as I do, just watching my surroundings.

In some cases, how you “prepare” may not be directly related to your specific medium. Can be from the coffee you are taking to the peer you are speaking to. Wherever this stage takes you, commit to it wholly and truly relish in it. Take notes. Observe what (and how) these other entities have created, lay down ideas as they come to you, colors that inspire you, sounds that move you, and words that catch you by surprise.

Incubation

Now is the time to let all that information and inspiration you just breathed in soak into your very core. In this stage, it may not even feel like you’re really doing anything since it’s your subconscious that’s actually doing all the work. In that sense, you can liken this step of the creative process to allowing a piece of steak to marinate overnight in a juicy bath of flavors. The meat is just sitting there to the naked eye, but a delicious transformation occurs, in reality occurs.

Insights

We alluded to a lightbulb flickering on in the previous stage, sending a person into a full-fledged creative frenzy they couldn’t possibly suppress. This moment is traditionally referred to as the “insight” stage of the creative process, or what some have playfully dubbed the “Eureka” moment.

This is the step we’re arguably most all familiar with, and the one we wrongfully assume is a stepping one. Perhaps this incorrect assumption causes many to conclude that you must be an inherently gifted creative person ever to experience such a moment. As you now know, the reality is that it might have taken days, weeks, months, or even years for such inspiration to hit. This is true even of the greatest artists our world has seen.

Another false assumption is that this Eureka moment is always loud and gut-punching powerful. While it does sometimes hit as an unmistakable spark of inspiration-born direction, it is important to note that sometimes the insight moment is more of a quiet, contemplative whisper. It also might not happen quite as cinematically as we’d like to think. Many even say that such inspiration strikes or develops when they least expect it — while making dinner, having a conversation with a friend, or in the middle of folding a giant load of laundry. The argument is that doing something that doesn’t require much brainpower gives your subconscious some time to churn.

Evaluation

The creative process would be remiss without acknowledging that not every creative idea is a great (or even good) idea worth pursuing. This is the phase where you really dig deep — as tricky and painful as it might be to your ego — and ask yourself if this is an idea that’s ultimately worth working on.

Instead of framing it as a potential way to squash your hopes and dreams, consider it an opportunity to put your idea to the ultimate test. Does it hold up against a flood of critical thinking, honest questions, and in some cases, the scrutiny of your peers?

Elaboration

Once your project idea has passed the scrutiny test, it’s finally time to “elaborate.” It’s officially time to put pen to paper, ink to canvas, and clay to the wheel in easier-to-understand terminology. This is the phase where you’re actively creating something and bringing your idea to life.

For many, this final step of the creative process can take just as long as all the other four put together (or even longer). It typically involves many hours of brainstorming the best approach and experimenting to figure out what works and what doesn’t. You might nail it on the first try (and some really do!), but what’s more likely to happen is that you create something, dislike it, and either rewind a bit or start completely from scratch. You might do this over and over again until it’s perfect in your eyes. Real sweat, real tears, and real joy are bred during this step of the creative process. Embrace it.


Laser and Light-based Treatment of Keloids

Laser and Light-based Treatment of Keloids

Keloids are an overgrowth of fibrotic tissue outside the original boundaries of an injury and occur secondary to defective wound healing. Keloid scars commonly grow beyond the wound boundaries, while hypertrophic scars are confined to the wound’s original area. Both types of scars arise as a result of impaired fibroblastic proliferation and collagen deposition after skin injury. Keloids often have a functional, aesthetic, or psychosocial impact on patients, as highlighted by quality-of-life studies. They can greatly affect the patient’s quality of life and emotional wellbeing by causing intense pain, itching, unappealing red appearance, and inexorable spread. Interestingly, keloids and hypertrophic scars are exclusively found in humans and do not occur in animals naturally. The lack of suitable animal models that recapitulate the key processes in keloidal/hypertrophic scarring has greatly hampered our understanding and treatment of these scars.

Treatments for keloids include surgical excision, intralesional or topical corticosteroids, other intralesional therapies: 5-fluorouracil (5-FU), bleomycin, and interferon, topical imiquimod, compression, cryotherapy, radiation, silicone sheeting, and laser or light-based therapies. Recurrence is common, even with combination therapy. Laser and other light-based technology have introduced new ways to manage keloids that may improve aesthetic and symptomatic outcomes and decrease keloid recurrence. Laser and light-based therapies for keloids can be grouped into three categories: ablative lasers, non-ablative lasers, and non-coherent light sources.

Non-ablative lasers target hemoglobin or melanin. 585 or 595-nm pulsed-dye lasers (PDL) are non-ablative, and the major chromophore is oxyhemoglobin. PDL also targets melanin; therefore, care must be taken to avoid pigmentary alterations. PDL is hypothesized to treat keloids by selective damage of blood vessels that supply the scar. The 980-nm diode laser targets hemoglobin and melanin. The 1064-nm neodymium-doped: yttrium, aluminum, and garnet laser and the 532-nm neodymium-doped: vanadate laser is hypothesized to primarily treat keloids by damaging deep dermal blood vessels.

Non-laser light sources are also used to treat keloids. These techniques include intense pulsed light therapy (IPL), light-emitting diode (LED) phototherapy, also known as low-level light therapy, and photodynamic therapy (PDT). These modalities utilize light energy that may cause keloid fibroblast functional modification. IPL emits non-coherent, broadband wavelength, pulsed light, and targets pigmentation and vasculature. LED phototherapy is hypothesized to photomodulate mitochondrial cytochrome C oxidase altering intracellular signaling. PDT requires the application of a photosensitizer, commonly 5-aminolevulinic acid or methyl aminolevulinic acid, that is preferentially absorbed by highly vascularized or metabolically active tissue and converted to protoporphyrin IX. Upon exposure to light, PpIX causes reactive oxygen species free radicals that have a cytotoxic effect. PDT may also cause alterations in extracellular matrix synthesis and degradation and modulate cytokine and growth factor expression.

The mechanisms by which topical PDT improves abnormal scars are largely unknown. However, they probably involve downstream responses to the ROS produced by the photodynamic reactions: the ROS induces membrane and mitochondrial damage, which activates signaling molecules such as TNF-α and interleukins 1 6 and cell death. The cell death may be via apoptosis, necrosis, and/or autophagy. These changes may alter growth factor and cytokine expression in the lesion, thereby modulating collagen production and extracellular matrix organization.

Notably, the shallowness of PDT suggests that it may be useful as an adjunct treatment of the wound area after keloid resection. In this setting, PDT may help to prevent postoperative keloid recurrence.

Blue & Red Light for Rosacea

Blue & Red Light for Rosacea

Rosacea is a common inflammatory skin condition affecting approximately 5% of the world population. Therapeutic approaches to rosacea are focused on symptom suppression employing anti-inflammatory agents. Photodynamic therapy, especially light-emitting diodes, has been introduced as a valid alternative to conventional therapy.

Because of rosacea's potential complexity, it has been classified into subtypes according to signs and symptoms that often occur together. Patients may have characteristics of more than one subtype at the same time. Although the cause of rosacea is unknown, several possibilities are currently being studied, including flushing, inflammatory pathways, and Demodex mites. Simultaneously, a growing range of therapies is available to address rosacea's signs and symptoms. While your doctor will tailor medical therapy to your individual case, treatment options may often be keyed to standard subtypes and level of severity.1

As with any medical therapy, outcomes of rosacea treatment may vary from case to case. Compliance with therapy — using your medication as your doctor prescribes — is an important key to success. Please consult a dermatologist or other physician to determine the appropriate therapy for your individual case.

Subtype 1: Facial Redness

Subtype 1 (erythematotelangiectatic) rosacea is characterized by flushing and persistent facial redness. Visible blood vessels may also be present, and facial discomfort is common.

Research into the physical processes involved in rosacea has recently led to new prescription therapy to relieve facial redness. It may also be important for you to identify and avoid lifestyle and environmental factors that trigger flushing or irritating your skin. The most common factors are covered in Rosacea Triggers, and a Rosacea Diary is available to help you identify and avoid those factors that affect your individual case.

The appearance of flushing, redness, and visible blood vessels may also be concealed with cosmetics, and facial discomfort may benefit from appropriate skincare, both discussed under Skin Care & Cosmetics.

Visible blood vessels and severe background redness may be reduced with lasers or intense pulsed light therapy. Several sessions are typically required for satisfactory results, and touch-up sessions may later be needed as the underlying disease process is still present.

In specific cases, extensive flushing may be moderated somewhat through the use of certain drugs.

Subtype 2: Bumps and Pimples

Subtype 2 (papulopustular) rosacea is characterized by persistent facial redness and acne-like bumps and pimples and is often seen after or at the same time as subtype 1. Fortunately, however, several medications have been extensively studied and approved for this common form of rosacea and may also be used on a long-term basis to prevent symptoms recurrence.

In mild to moderate cases, doctors often prescribe oral and topical rosacea therapy to bring the condition under immediate control, followed by long-term use of topical therapy alone to maintain remission. A version of oral therapy with less risk of microbial resistance has also been developed specifically for rosacea and is safe for long-term use.

Higher doses of oral antibiotics may be prescribed, and other drugs may be used for patients who are unresponsive to conventional treatments.

Subtype 3: Skin Thickening

Subtype 3 (phymatous) rosacea is characterized by skin thickening and enlargement, most frequently around the nose. This condition develops primarily in men. Although mild cases may be treated with medications, moderate to severe manifestations, typically require surgery.

A wide range of surgical options is available, including cryosurgery, radiofrequency ablation, electrosurgery tangential excision combined with scissor sculpturing, and skin grafting. A surgical laser may be used as a bloodless scalpel to remove excess tissue and recontour the nose, often followed by dermabrasion.

Subtype 4: Eye Irritation

Subtype 4 (ocular) rosacea is characterized by any one of many eye symptoms, including a watery or bloodshot appearance, foreign body sensation, burning or stinging, dryness, itching, light sensitivity, and blurred vision. A history of having styles is a strong indication and has “dry eye” or blepharitis.

Treatment for mild to moderate ocular rosacea may include artificial tears, oral antibiotics, and the eyelashes' daily cleansing with baby shampoo on a wet washcloth. More severe cases should be examined by an eye specialist, who may prescribe ophthalmic treatments, as potential corneal complications may involve visual acuity loss.

Treatment and Conditions


Currently, there are two traditional treating methods, such as medications and physical treatment. Doctors can prescribe medications. Usually, the medications are antibiotics. The thing is, however, there are side effects from the antibiotics. Additionally, there is no proof that Rosacea is a bacterial condition. So the effectiveness of treatment could remain uncertain. Plus, going to see a doctor can be time-consuming & money consuming.

Physical treatment can be soup or gel to help better improve the skin. However, people have different skin types. Usually, it is super expensive to diagnose the skin condition in great detail; people have different skin types. The wrong usage of beauty products could lead to worsen skin problems or increase sensitivity.

Several therapeutic approaches are currently available for treating rosacea, and they are mainly aimed at controlling disease symptoms. The therapeutic plan has to be adapted to the rosacea subtype and tailored according to the patient's dominant manifestations. In general, the reduction of oral therapy in favor of topical or physical therapy is desirable to reduce side effects for patients and increase the treatment's safety.

The therapeutic approach has blue (480 nm ± 15 nm) and red (650 ± 15 nm) LED light-based therapy in patients affected by rosacea. Previous research reported the efficacy of red and blue light coupled with mild to moderate acne lesions. Blue light (400–470 nm), due to its lower penetration, is useful in such skin conditions related to the skin's epidermis layer; therefore, it can also interfere with human sebocyte proliferation. On the other hand, red light (630 nm) is reported to affect sebum production significantly. The benefits deriving from PDT using LEDs are not limited to its efficacy but are also related to its safety and tolerance by patients; therefore, its advantages can be extended to a broad range of dermatological conditions.

References:

Two AM, Wu W, Gallo RL, Hata TR. Rosacea: part I. Introduction, categorization, histology, pathogenesis, and risk factors. J Am Acad Dermatol. 2015;72(5):749–58. quiz 759–60. PMID: 25890455

Plewig G, Kligman AM. History of Acne and Rosacea. In: ACNE and ROSACEA. Berlin: Springer; 2000.

Odom R, Dahl M, Dover J, Draelos Z, Drake L, Macsai M, Powell F, Thiboutot D, Webster GF, Wilkin J. Standard management options for rosacea, part 2: Options according to subtype. Cutis, 2009;84:97–104.

Kolontaja-Zauber, I., Ināra Ančupāne, Andra Dērveniece, Aija Žileviča, & Ilze Ķikuste. (, 2018). Impact of intense pulsed light therapy on the quality of life of rosacea patients. Proceedings of the Latvian Academy of ences Section B Natural Exact and Applied sciences, 72(1), 9–15.

Kim, B. Y., Moon, H. R., & Ryu, H. J. . (2018). Comparative efficacy of short-pulsed intense pulsed light and pulsed dye laser to treat rosacea. Journal of Cosmetic & Laser Therapy, 1–6.

Bo, Young, Kim, Hye-Rim, Moon, & Hwa, et al. (2018). Comparative efficacy of short-pulsed intense pulsed light and pulsed dye laser to treat rosacea. Journal of Cosmetic & Laser Therapy Official Publication of the European Society for Laser Dermatology.

Smith, J. P. K. . (1984). The eyes have it: young children’s discrimination of age in masked and unmasked facial photographs. Journal of Experimental Child Psychology.


Red Light Therapy and Sun Damage

Red Light Therapy and Sun Damage

When summer rolls around, we all head outside, absorbing as many rays as we can. And the proof is in the numbers, with the top five summertime activities being barbeques, going to the beach, attending festivals, going for a hike, and exploring nature. When the sun comes out, people flock to the outdoors with good reason. We need the sun’s rays to survive.

However, many of us go a little overboard. Some lather on tanning oil or skip sunscreen to make sure we receive as much pigmentation as possible. And yes, we need vitamin D, but overexposure leads to sun damage, including sunspots and wrinkles.

However, it doesn’t end there. Neglectful sun exposure can also lead to skin cancer. While the damage has already been done from years of sunbathing and tanning oils, there are ways we can repair sun-damaged skin, reduce wrinkles and sunspots.

It can help repair the sun damage done to our skin and turn back the clock with red light therapy.

What is Sun Damage?

In the end, skin damage comes from overexposure to ultraviolet (UV) light. When we sunbathe, our skin naturally responds to the sun by protecting itself from UV light. What does our body do? Well, it produces melanin, which darkens the skin to reflect the UV light. So your summer tan is actually a defense mechanism. There are a few different types of sun damage to be aware of:

Melasma: It’s an overproduction of melanin that causes brown or gray patches to form on the skin.

Wrinkles: UV light breaks down the collagen and elastin in the skin, losing its firmness and causing wrinkles.

Sunburn: Sunburns are an inflammatory reaction to UV radiation damage to the skin. The body responds by repairing or removing the damaged cells, which results in redness and peeling.

Sun Spots: Overexposure to UV rays causes an increase of melanin production that builds up in clusters, producing dark spots on the skin.

Actinic Keratosis (AK): Causes a scaly patch of skin on the body from overexposure to UV light. This is particularly dangerous as around 10% of actinic keratosis becomes cancerous.

How Red Light Therapy Reverses Sun Damage

If you’re wondering whether sun damage is reversible or not, the answer is yes. Red light therapy uses infrared and red light to enhance the body’s healing process. Red light therapy increases the body’s collagen, elastin, and immune response; it can remove and repair dead or damaged skin cells.

By increasing collagen production, it’ll help smooth and firm the skin, reducing the appearance of fine lines and wrinkles. Besides, red light therapy also protects existing collagen, which helps keep the skin’s elasticity.

However, red light therapy doesn’t only reduce fine lines and wrinkles. It can also help with more serious skin conditions such as actinic keratosis. It can aid in removing actinic keratosis spots from the skin with photosensitizing medication and red light therapy.

Sun damage is the main cause of aging skin and can lead to serious health issues. Naturally, some sun damage forms cannot be treated, especially for those who work consistently outdoors. However, tackling sunspots, wrinkles, sunburns, and actinic keratosis is achievable through red light therapy treatment.

It’s important to point out that while red light therapy does reverse sun damage, it can prevent future damage — but you should always wear a broad-spectrum sunscreen when outdoors and reapply after swimming or sweating.

Reversing past mistakes are possible with light therapy, but we also want to look at the future. Luna’s red light therapy will tackle previous sun damage and rejuvenate the skin, while sunscreen will prevent future damage.

We hope you continue to enjoy the sun’s incredible rays safely while enjoying the incredible skincare results of Lunas light panels.

Light & Food Preservation

Light & Food Preservation

Consumers demand high-quality processed foods with minimal changes in nutritional and sensory properties. Nonthermal methods are considered to keep food quality attributes better than traditional thermal processing. Pulsed light (PL) is an emerging non-thermal technology for decontamination of food surfaces and food packages, consisting of short time high-peak pulses of broad-spectrum white light. It is considered an alternative to continuous ultraviolet light treatments for solid and liquid foods. This paper provides a general review of the principles, mechanisms of microbial inactivation, and PL treatments applications on foods. Critical process parameters that are needed to be optimized for better efficiency of PL treatments are also discussed. PL has considerable potential to be implemented in the food industry. However, technological problems need to be solved to avoid food overheating and achieve better penetration and treatment homogeneity. Besides, more extensive research is needed to understand how PL affects quality food attributes.

Nonthermal technologies

Nonthermal technologies are being applied in food processing as a viable alternative to thermal processing. Traditionally, most foods are thermally processed by subjecting them to temperatures between 60 °C for a few minutes and 100 °C for a few seconds. During this period, a large amount of energy is transferred to the food, which may trigger reactions that lead to undesirable changes or by-products formation. During nonthermal processing, food temperature is held below that achieved in thermal treatments. Thus, vitamins, essential nutrients, and flavors are expected to undergo minimal or no changes.

Pulsed light (PL) is used for the rapid inactivation of microorganisms on food surfaces, equipment, and food packaging materials. The terms high-intensity broad spectrum pulsed light and pulsed white light are synonymous with PL.

Inert-gas flash lamps generate intense and short pulses of ultraviolet (UV) light for microbial inactivation started during the late 1970s in Japan. In 1988, extensive experimentation carried out by PurePulse Technologies Inc. provided a pulsed light process called PureBright® to sterilize pharmaceuticals, medical devices, packaging, and water. The process's efficacy was tested against a broad range of microorganisms, including bacteria (vegetative cells and spores), fungi, viruses, and protozoa. However, the food industry adopted the technology only in 1996, when the Food and Drug Administration approved the use of PL technology for the production, processing, and handling of foods.

Description of PL

PL involves the use of intense pulses of short duration and a broad spectrum to ensure microbial inactivation on the surface of either foods or packaging materials. Electromagnetic energy is accumulated in a capacitor during fractions of a second and then released in the form of light within a short time (nanoseconds to milliseconds), resulting in an amplification of power a minimum of additional energy consumption (Dunn et al. 1995). Typically, the equipment used to produce PL comprises one or more adjustable xenon lamp units, a power unit, and a high-voltage connection that allows the transfer of a high current electrical pulse. As the current passes through the lamp unit's gas chamber, a short, intense burst of light is emitted. The light produced by the lamp includes broad-spectrum wavelengths from UV to near-infrared. The wavelength distribution ranges from 100 to 1,100 nm: UV (100–400 nm), visible light (400–700 nm), and infrared (700–1,100 nm). Pulses of light used for food processing applications typically emit 1 to 20 flashes per second at an energy density in the range of about 0.01 to 50 J cm−2 at the surface (Barbosa-Canovas et al. 1998).

Liquid Foods

Many fluids, such as water, have a high degree of transparency to a broad range of wavelengths, including visible and UV light. Other liquids, such as sugar solutions and wines, exhibit more limited transparency. Increasing the number of solids will diminish the intensity of UV radiation's penetration. In an aqueous solution, the lower the transparency, the less effective the PL treatment. Liquids with high UV absorbance must be treated as a thin layer to reduce the liquid's radiation absorption. In this manner, the liquid's UV absorption is low, and bacteria are more likely to be subjected to lethal doses. The absorbance of clarified fresh juices and juices containing pulp varies considerably. Clarified apple juice has a low absorbance, with absorption coefficients about 11 cm−1, whereas absorbance of orange juice can achieve values close to 50 cm−1. A positive correlation between vitamin C content and the absorption coefficient of clear apple juices was observed.

Conclusions

PL is a novel non-thermal technology to inactivate pathogenic and spoilage microorganisms on foods. The significant microbial reductions in short treatment times, the limited energy cost of PL, the lack of residual compounds, and its great flexibility are some of the technique's major benefits. This method is clearly efficient in inactivating microorganisms in vitro, but its potential for real foods is still under investigation. Further studies need to be conducted to assess PL treatments' effects on food properties beyond safety and spoilage. There is a need for optimizing the critical process factors to achieve the target inactivation level for specific food applications without affecting quality. PL equipment with good penetration and short treatment times need to be designed for commercial purposes. Also, the applicability of PL treatments on an industrial scale needs to be compared with other nonthermal or conventional thermal processes.

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Stretch Marks & Light Therapy

Stretch Marks & Light Therapy

Why Do We Get Stretch Marks?

A stretch mark is a type of scar called striae, meaning “thin, narrow scar”. In people who develop stretch marks, the skin has stretched faster than it can grow, such as during pregnancy, growth spurts, or rapid fat or muscle gain. The abrupt stretching causes the collagen and elastin proteins responsible for the skin’s structure and elasticity to rupture. This, in turn, causes the dermis to tear.

As the dermis tears, the body’s healing mechanisms spring into action to close the wound as quickly as possible to prevent infection and further damage.

Normally, as the skin regenerates and grows, it’s an elegantly organized latticework of collagen and elastin proteins. But when the skin tears, the body doesn’t have time to build an elegant structure to fill in the gap. Time is of the essence in any wound repair, including torn skin.

The collagen clumps together hurriedly, aiming for efficient closure of the wound before infection can set in. “Scarring is the result of a system that has learned to respond extremely quickly to a wound,” says Dr. John Newman, a cosmetic surgeon and researcher at the Laser Center of Virginia in Virginia Beach.

This haphazard process results in tough and functional but unattractive tissue — what we know as a scar. “It is kind of like nailing down a crisscross of two-by-fours over a hole in a deck,” says Newman. “It seals the hole, but it doesn’t look very nice.”

Newly formed stretch marks are darker than the surrounding skin and can be slightly raised, itchy, or painful. If they’re left untreated, they become permanent scars. Their color will lighten, and their appearance will fade below the top layer of the surrounding skin.

The bigger mystery is why stretch marks don’t disappear over time as the skin regenerates. The key lies in the information that emerging cells receive from adult cells in the area. Skin cells, whether they’re normal cells or scar cells, regenerate about once every 30 days. Growth of new skin cells begins at the bottom-most layer of the scar, and older (dying) cells are pushed to the surface where they naturally slough off.

However, Neuman explains that that that that emerging cells “learn” from their immediate neighbors and predecessors and develop the same characteristics as ir replacement their replacement cells. As a result, any emerging cell in contact with scar cells will become new scar tissue rather than normal skin tissue.

Red Light Therapy For Stretch Marks

If you have tried to get rid of stretch marks, perhaps you’ve used specialized creams that contain retinoids. These work to some extent, but only if you catch your stretch marks early and treat them while they’re still forming. Retinoids work by stimulating collagen production. However, they can irritate sensitive individuals, and doctors often recommend that pregnant women avoid anything containing retinoids.

Another common treatment, known as microdermabrasion, essentially involves “sandblasting” the skin with tiny crystals. This sloughs off dead skin

cells and stimulates the production of collagen. Microdermabrasion is a fairly harsh treatment that can lead to irritation and damage, especially to sensitive skin.

The most extreme treatment for stretch marks is plastic surgery, such as a mini tummy tuck. This may be effective, but there are risks associated with any invasive procedure and the high cost.

Is there a better option for restoring the appearance of the skin? The answer is yes, absolutely. Also known as photobiomodulation and low-level light therapy (LLLT), red light therapy improves skin appearance, reduces signs of aging, treats chronic skin conditions, reduces scarring, and promotes skin wound healing.

When red light therapy is used, visible red light and invisible near-infrared (NIR) light are applied to the skin with LED bulbs' devices. Wavelengths of light are measured in nanometers (nm), with red light ranging from 630nm to 660nm and NIR light ranging from 810nm to 850nm. Human cells respond favorably to these wavelengths, similar to how natural sunlight affects plant cells by stimulating more energy and optimization of cell function.

When the red light is shone on bare skin, it soaks into the mitochondria, colloquially referred to as the powerhouses of cells' energy factories. The mitochondria are, in turn, stimulated to produce more adenosine triphosphate (ATP), which is the primary cellular fuel. This energizes cells to perform their normal functions, from fighting off pathogens to performing repair and regeneration.

Improved Blood Flow

Proper healing relies on good circulation to the skin. Red light promotes the proliferation of endothelial cells, which make up the inner layer of capillaries (the tiny blood vessels that deliver oxygen and nutrients throughout the body). This was the focus of a 2017 study by a team of researchers from Austria, who found that red light consistently increased migration and proliferation of endothelial cells.

Without proper blood circulation, there would be no healing since endothelial cells also deliver white blood cells to the sites they need. In skin wound healing, white blood cells are necessary to protect the vulnerable area from infection while the wound closes up.

Reduced Inflammation

Acute inflammation results in the redness that’s noticeable in fresh stretch marks. This is a normal and necessary part of the tissue regeneration scar's process. Acute inflammation, which is a function of the immune system, actually sets the stage for normal tissue repair and regeneration. Inflammation is quickly followed by the production of new skin structures — which, as previously described, are hastily assembled to ensure that the torn skin doesn’t become infected.

But sometimes, the inflammatory process continues after the wound has healed, leading to chronic inflammation. It can lead to a variety of widespread problems throughout the body, including disease. “Some inflammation is good,” says Dr. Robert H. Shmerling, an associate professor of medicine at Harvard Medical School. “Too much is often bad. The goal is to recognize when inflammation is simply doing its job, and when it can potentially cause problems.”

Hundreds of studies have shown how red light therapy can significantly reduce inflammation. Many of these were conducted by Dr. Michael A. Hamblin, an associate professor of dermatology at Harvard Medical School and a noted expert on red light therapy. In the final report of a 2017 study, Hamblin refers to red light therapy’s “pronounced anti-inflammatory effects.”

Mobilize Stem Cells

During the skin-rebuilding phase, stem cells, which are unspecialized “master” cells, mobilize to the site and develop into most any type of specialized cells that are needed by the body. Ideally, they develop into normal skin cells, rather than scar tissue, to replenish damaged or destroyed cells due to skin tearing.

Red light has been shown to activate stem cells. As Barbara Gefvert, editor-in-chief of BioOptics World, explains: “Recent research shows … that noninvasive application of light can boost the natural growth of an individual’s own stem cells to enable exciting new treatments.” Stem cells can assist with the tissue regeneration process and stimulate normal and healthy behavior in existing cells. This can prevent the formation of new stretch marks and gradually reduce the appearance of existing stretch marks.



How Red Light Therapy Combats Arthritis Pain & Stiffness

How Red Light Therapy Combats Arthritis Pain & Stiffness

When it comes to muscle and joint stiffness, osteoarthritis, and arthritis, the one thing in common is pain and inflammation. When suffering from joint and muscular conditions, a person’s range of motion decreases, and swelling and skin redness increase, making everyday tasks a struggle.

Many young to middle-aged people are unaware of these conditions as they’ve been labeled as conditions mainly for the elderly; however, things have changed.

Though these conditions are common within the elderly community, we’re seeing an increase among young adults. In the United States alone, 23% of adults — over 53 million people — have arthritis, according to the Centers for Disease Control and Prevention (CDC). In other words, joint pain isn’t just for old age, as we once thought.

Rheumatoid arthritis (RA) appears in every 8 in 100,000 people between 18 and 34 years old. Of course, no one — young or old — wants to wake up feeling joint stiffness, swelling, or pain every morning.

However, the old myth that arthritis is untreatable is about to be debunked with light therapy.

Naturally, a medical professional will have to make a conclusive arthritis diagnosis. However, once diagnosed, many people find home treatments to deal with the pain — like light therapy. And the people who are undergoing light therapy are receiving incredible pain relief from their treatment. For example, a study published in the Turkish Journal of Physical Medicine and Rehabilitation found that infrared light treatment on inflammatory arthritis of the spine (spondylitis) encouraged increased function and improved quality of life for participants.

But what’s the science behind red light therapy treating joint conditions? Red light therapy uses low levels of red light to stimulate a natural response to cell performance. The light penetrates through the layers of the dermis, entering the muscles and nerves. As the cells absorb the energy, they become more active, with increased blood flow to the treated area, promoting cell regrowth and regeneration. Through this combination of increased blood flow and cellular activity, it rapidly reduces inflammation and pain.

With the recent advancements in modern technology, those who have arthritis or other joint conditions no longer need to opt for nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids. These forms of the medication come with serious side effects such as edema, heartburn, stomach ulcers, cataracts, bone loss, and elevated blood clots. This alternative non-invasive treatment allows people to choose a drug-free treatment that reduces swelling, inflammation, and pain through red light therapy.

A study published in the National Library of Medicine found that elderly patients who underwent red and infrared therapy treatment had reduced their pain by 50%. Besides, they found participants who underwent red and infrared light therapy had a significant improvement in function. Another study from 2016 saw a substantial reduction in pain and an increased range of motion after five to seven red light therapy treatments for Bouchard’s and Heberden’s osteoarthritis. These studies are only a few examples of how red light therapy shows results as an effective treatment.

A little red light can go a long way for your body, mind, and soul. More and more people recognize the benefits of red light therapy as a natural home treatment. For people suffering from any joint condition, red light therapy will reduce inflammation, eliminating joint and muscle pain.

But there’s more to red light therapy than this. It’s important to be reminded that light therapy also heals other ailments in the body. Red light therapy is effective for injuries, muscle recovery, cancer side effects, skincare, and depression.

With an FDA-approved and MDA-certified Lunas red light therapy device, users can achieve optimal therapeutic results by merely exposing their bare skin to the light for a few minutes per day. Healing yourself doesn’t need a lot of time or money; you need the right tools. Lunas light therapy devices have the power to heal bodies and minds all around the world.

The Sun and Us

The Sun and Us

Nothing is more important to us on Earth than the Sun. Without the Sun’s heat and light, the Earth would be a lifeless ball of ice-coated rock. The Sun warms our seas, stirs our atmosphere, generates our weather patterns, and gives energy to the growing green plants that provide the food and oxygen for life on Earth.

We know the Sun through its heat and light, but other, less obvious aspects of the Sun affect Earth and society. Energetic atomic particles and X-rays from solar flares and other disturbances on the Sun often affect radio waves traveling the Earth’s ionosphere, causing interference and even blackouts of long-distance radio communications. Disturbances of the Earth’s magnetic field by solar phenomena sometimes induce huge voltage fluctuations in power lines, threatening to blackout cities. Even such seemingly unrelated activities as the flight of homing pigeons, transatlantic cable traffic, and the control of oil flow in the Alaska pipeline apparently are interfered with by magnetic disturbances caused by events on the Sun. Thus, understanding these changes — and the solar events that cause them — is important for scientific, social, and economic reasons.

We have long recognized the importance of the Sun and watched it closely. Primitive people worshiped the Sun and were afraid when it would disappear during an eclipse. Since the early seventeenth century, scientists have studied it with telescopes, analyzing the light and heat that manage to penetrate our absorbing, turbulent atmosphere. Finally, we have launched solar instruments and ourselves-into space to view the Sun and its awesome eruptions in every aspect.

Once we looked at the Sun by the visible light that reached the ground, it seemed an average, rather stable star. It was not exactly constant, but it seemed to vary in a fairly regular fashion, with a cycle of sunspots that comes and goes in about eleven years. Now the Space Age has given us an entirely different picture of the Sun. We have seen the Sun in other forms of light-ultra violet, X-rays, and gamma rays that never reach the ground from space. This radiation turns out to be far more responsive to flare eruptions and other so-called solar activity.

We now see the Sun as a place of violent disturbances, with wild and sudden movements above and below its visible surface. Besides, solar activity's influence seems to extend to much greater distances than we had believed possible. New studies of long series of historical records reveal that the Sun has varied in the past in strange and unexplained ways. Scientists wonder how such variations might affect the future climate on Earth.

We have obtained a clearer picture of the scope of the Sun’s effects. Its magnetic field stretches through interplanetary space to the outer limits of the solar system. Steady streams and intense storms of atomic particles blow outward from the Sun, often encountering our Earth's atmospheres and the other planets. The spectacular photos of the Earth from space show only part of the picture. Instruments carried on satellites reveal a wide variety of invisible phenomena — lines of magnetic force, atomic particles, electric currents, and a huge geocorona of hydrogen atoms — surrounding the Earth. Each is as complex and changing as the visible face of the globe. The Earth’s magnetic field extends tens of thousands of miles into space, and many different streams of electrons and protons circulate within it. Huge electric currents flow around the Earth, affecting their high-altitude surroundings as well as our environment at ground level.

Space observations have greatly expanded our ability to look at the Sun, interplanetary space, and the Earth's immediate surroundings. We can now “see” many phenomena that are completely undetectable from the Earth’s surface, and we now have a much better, more complete, and more coherent picture of how events in one part of our solar system relate to activity in another.

The Sun as a Star

We sometimes forget that there is one star that is easily visible in the day time: our Sun. The Sun is the only star close enough to be studied in detail, but we are confident that all the processes in the Sun must also occur in billions of distant stars throughout the universe. To understand the nature and behavior of other stars, we must first understand our own. At the same time, observations of other kinds of stars help put the Sun in perspective.

The Sun is a relatively typical star among the approximately 100 billion stars in our Milky Way galaxy. The masses of most other stars that we see range from approximately one-tenth of the mass of the Sun to about 30 solar masses. The surface temperatures of most stars range from about 2000° C to 40,000° C. Although the Sun is somewhat on the cool side at about 6000° C, hot stars are rare, and most normal stars are cooler than the Sun. Compared to some of the explosive stars — novae, and supernovae — which sometimes appear in the sky, the Sun is stable and ordinary.

This long-term stability of our Sun probably was crucial for the development of life on Earth. Biologists believe that a relatively stable average temperature had to prevail on Earth during the past 3 billion years for life to evolve to its present state. The relative stability of the Sun is also important to astronomers trying to understand the basic nature of it and other stars. Violent activity in the Sun could mask the more subtle and long-enduring processes, which are the basic energy transport mechanisms of our star. Fortunately, they are not hidden, and we have been able to map the trend in solar properties with height above the visible surface.

Above the minimum temperature region in the photosphere, we have measured how the gas gets hotter as it thins out with height. The chromosphere and corona, each hotter than the layer below, are warmed by the transfer of energy from below through processes that are still not well understood.

Until space observations became possible, we knew nothing about coronae in any other stars and had only marginal information about stellar chromospheres' properties. Now, space observations have shown us that a large fraction of the stars in the sky have chromospheres and coronae.

On several dozen stars, we have even detected activity that may be connected with sunspot (or “starspot”) cycles like those of our own Sun. X-ray telescopes carried on satellites have recorded flares in other stars that are far more powerful than the already impressive flares of the Sun. By observing the strength and frequency of these events on stars with masses, ages, and rotation rates which differ from those of the Sun, we search for answers to such basic questions as: “How does the sunspot cycle period depend on the star’s rotation rate?” or “What is the relation between the temperature of a star’s corona and the strength of its magnetic field?” By deciphering the general pattern of stellar properties, we can better understand what makes things happen on the Sun.

The Sun presents us with a bewildering variety of surface features, atmospheric structures, and active phenomena. Sunspots come and go. The entire Sun shakes and oscillates in several different ways at the same time. Great eruptions called prominences hang high above the Sun’s surface for weeks, suspended by magnetic force, and sometimes shoot abruptly into space from the corona. The explosions called solar flares emit vast amounts of radiation and atomic particles in short periods of time, often with little or no warning.

Space observations have discovered many new aspects of solar events hidden from ground-based observatories—the Sunshine's hottest spots primarily in ultraviolet and X-rays, rather than in visible light. Thus, only from space can we map high-temperature solar flares' true structure and determine their physical conditions. Space observatories have shown us the higher, hotter layers of the Sun’s atmosphere that normally are invisible from the ground. Instruments on satellites revealed that in flares and other violent disturbances, the Sun acts like an atomic accelerator, driving electrons and protons to velocities approaching the speed of light. At such high speeds, the particles emit the high-energy X-rays and gamma rays measured by our satellites. Sometimes they even induce nuclear reactions on the surface of the Sun.

Two aspects of our improved knowledge of the Sun deserve special attention. One is the role of magnetic fields in determining virtually all aspects of the Sun’s upper atmosphere's structure and behavior. The other is discovering the solar wind, a stream of atomic particles that constantly evaporate from the Sun’s atmosphere and are accelerated to speeds of hundreds of kilometers per second, escaping into space in all directions.

The Earth-Sun Battle

For any solar particle to reach the Earth, it must first pass through the Earth’s magnetic field. Before the solar wind was discovered, the Earth’s field was thought to be symmetrical, resembling a huge bar magnet, fading off indefinitely into space. However, we now know that the solar wind shapes the Earth’s magnetic field's outer regions and is sharply bounded. Outside the boundary, space is dominated by the solar wind and the interplanetary magnetic field. Inside the boundary is the region or magnetosphere dominated by the Earth’s magnetic field. The measurements from many space missions have been combined to reveal that the solar wind blows out the Earth’s magnetosphere into a teardrop shape. The head of the drop extends only about 10 Earth radii, or about 65,000 kilometers (40,000 miles) “upwind” toward the Sun. The tail of the drop stretches away in the direction opposite the Sun, actually reaching beyond the Moon’s orbit. This long magnetotail extends more than 600,000 kilometers (370,000 miles) from the Earth.

At the boundary of the magnetosphere, there is a constant struggle between the Earth's magnetic field and the forces of the Sun. Buffeted by fluctuations in the solar wind velocity and density, the magnetosphere’s size and shape are continuously changing. When the solar wind strikes the magnetosphere, shock waveforms are analogous to the sonic boom preceding a supersonic airplane. Inside the boundary with the solar wind, the magnetosphere remains an active region. It contains two belts of very energetic charged atomic particles trapped in the Earth’s magnetic field hundreds of miles above the atmosphere. These belts were discovered by Professor James Van Allen of the University of Iowa and his colleagues in 1958, using simple radiation detectors carried by Explorer 1, the first U.S. satellite.

The Northern and Southern Lights: Gifts from the Sun

The structure of the Earth’s magnetosphere also controls aurorae's behavior, seen in our night skies. Pre-Space Age textbooks stated that aurorae are produced by photons emitted from the Sun and reach the Earth’s upper atmosphere through gaps in the Earth’s magnetic field at the north and south magnetic poles. According to the theory, these protons strike oxygen atoms in the atmosphere, and the collisions cause the glow, which we call the Northern Lights.

This view has changed in the Space Age. The data collected by many spacecraft showed that the situation is more complicated. Particles from both the solar wind and from the Earth’s atmosphere apparently are stored in the magnetotail. From there, they periodically are violently ejected into the northern and southern polar regions of the atmosphere along the Earth’s magnetic field. They are accelerated to high speeds by a process not yet fully explained. The magnetotail is, in effect, a reservoir of particles that is periodically refilled. When the Sun is active during maximum sunspot years, this process is especially intense and frequent, and the aurorae are brighter and move closer to the equator.

Bipolar Disorder & Light Therapy

Bipolar Disorder & Light Therapy

I have a friend who often shows extreme shifts in moods. Sometimes I see an extremely elevated mood, and sometimes, it's depression. On some days, I see episodes of uplifted feelings and depression at the same time.

Strange right!

Later I figured out that she was going through a mental illness called bipolar disorder. This isn’t a rare brain disorder. In fact, about 15 million U.S adults suffer from this disorder.

Bipolar disorder is a mental illness characterized by dramatic transfer in mood and behavior. Bipolar depression can last from several days to years, depending on the person's type and state.

Let’s put light on some of the unknown facts of Bipolar Disorder.

  • Firstly we need to understand that bipolar depression has several types. It is distinguished by profuse behaviors, moods, depression, and, yes, mixed emotions. The symptoms of this illness can present at different severities and in many combinations in different people. So, it may not be the same for every person who has Bipolar disorder.

We basically classify the states into two broad classes:

  • Manic — overly elevated emotions, increase in energy, higher self-confidence, and decreased need for sleep.
  • Depression — sad, worthless, suicidal, low feelings
  • It is possible that people can experience symptoms of mania and depression at the same time.
  • The length of mood episodes and varying behavior can vary from person to person.
  • There is no known single cause of this mental illness.
  • Not only adults but children and teenagers can have bipolar disorder too.
Light Therapy — the Bipolar Disorder Soother!

If we compare other types of depression, there are fewer treatments available for bipolar disorder.

Hence, it is important to find an effective treatment for your illness.

Antidepressant medications, on the other hand, are not clearly effective. They may aggravate the mood cycling in people with bipolar disorder. Also, many people with bipolar disorder are prescribed to take other medications like mood stabilizers.

That’s why it is important to go for a non-medication treatment, like light therapy!

But why is it recommended? Light therapy is more effective, non-invasive, and absolutely safe because it can be used without worrying about additional drug interactions.

But How Light Therapy Helps?

Humans have natural 24-hour clocks, which are disrupted in bipolar disorder. One way of treating bipolar disorder is to handle the circadian rhythm (24*7 natural cycle that regulates the physical, mental, and behavior changes). And this can be achieved with bright light therapy.

The light emitted during light therapy activates the retina in the eye, resulting in a stimulus being transmitted from the eye to the brain's hypothalamus. The hypothalamus is a part of the brain that has a vital role in regulating mood. It also helps control many bodily functions, such as the release of hormones from the pituitary gland and channelizing the mood.

The light acts through the eyes to regulate the biological clock located in a tiny brain region. There are disturbances in the biological clock that affect circadian rhythms in people with bipolar disorder, including hormonal rhythms, sleep, feelings, cognition, and other behaviors.

Light therapy triggers the hypothalamus and helps bipolar patients to calm their emotional flow and have normal behavior.

Studies have shown that light can affect the major neurotransmitters, or chemical messengers, involved in mood and behavior, e.g., serotonin and dopamine. So, light therapy may act similarly to antidepressants by directly working on these neurotransmitters.

We found trials of light therapy compared to a placebo in people with bipolar depression. The studies' results displayed a significant improvement in depressive symptoms with bright light compared to placebo conditions.

I recommended my friend to you light therapy, and that really helped her. The quality of personal life is great since then. If you are also like my friend who is dealing with bipolar disorder, you possibly got the remedy.

Remember, your Mental Health matters!!

References:

Stroke Incidents & Red Light Therapy

Stroke Incidents & Red Light Therapy

According to the Centers for Disease Control and Prevention, approximately 800,000 stroke incidents occur every year. No two-stroke incidents are the same. Stroke patients suffer complications such as loss of motor skills or partial paralysis on one side of the body.

A person can feel excruciating muscle pain, contractions for long periods of time, or spasms during the recovery process. This muscle tightness is known as spasticity or hypertonia. Sometimes patients experience muscle weakness down one side of the body, known as hemiparesis. One of the best treatments for muscle spasticity and strengthening muscle function is physical therapy.

The recovery process is dependent on the continued movement of the affected muscles. For example, some patients are known to keep their affected shoulder tense due to pain from the arm remaining relaxed and hanging. This leads to more complications, pain, and tightness. Everyday tasks such as lifting a fork, sweeping a floor, or driving a car can feel impossible for some. While pain is felt in the shoulder, arm, or leg muscles — these muscles are mostly healthy. It is the brain circuits and nerves between the brain's connection to these body parts that are damaged and need to be strengthened. Often, stroke patients do not find relief from even the strongest pain medication. Regardless, stimulating the muscles and pained areas with physical therapy strengthens the brain's connection and generates the healing process.

The National Library of Medicine has shared a study conducted in 2016 on stroke patients and red light therapy. The study concluded that red light therapy “may contribute to increased recruitment of muscle fibers and, hence, to increase the onset time of the spastic muscle fatigue, reducing pain intensity in stroke patients with spasticity, as has been observed in healthy subjects and athletes.” Another study from The National Library of Medicine on the effect of Photobiomodulation by red light-emitting diodes (LEDs) on nerve regeneration concluded with positive results. It was found in 2010 that “red to near-infrared LEDs have been shown to promote mitochondrial oxidative metabolism. In this study, LED irradiation improved nerve regeneration and increased antioxidation levels in the chamber fluid. Therefore, we propose that antioxidation induced by LEDs may be conducive to nerve regeneration.” Red light therapy works well to stimulate mitochondrial functions in cells and nerves. It can stimulate recovery 4 to 10 times faster than your body’s natural healing process.

Physical therapy is necessary for stroke patients, and when paired with full-body red light therapy, there is the potential to assist efforts towards pain reduction significantly. Photobiomodulation or red light therapy stimulates cells and helps repair the myelin sheath covering nerve fibers to accelerate their healing process and can have a positive effect on repairing broken neural pathways in the brain disrupted by stroke incidents.

In Kaiyan Medical, we develop all types of light therapy devices. We believe in the holistic approach to balance your body.

References

https://www.stroke.org.uk/sites/default/files/pain_after_stroke.pdf

https://pubmed.ncbi.nlm.nih.gov/27299571/

https://pubmed.ncbi.nlm.nih.gov/20358337/#:~:text=Red%20to%20near%2Dinfrared%20LEDs,be%20conducive%20to%20nerve%20regeneration.

Brainwaves - Get to Know your Brain

Brainwaves - Get to Know your Brain

Brain waves are oscillating electrical voltages in the brain, measuring just a few millionths of a volt. At the root of all our thoughts, emotions, and behaviors are the communication between neurons within our brains. Brainwaves are produced by synchronized electrical pulses from masses of neurons communicating with each other.

Brainwaves are detected using sensors placed on the scalp. They are divided into bandwidths to describe their functions but are the best thought of as a continuous spectrum of consciousness, from slow, loud, and functional — to fast, subtle, and complex.

It is a handy analogy to think of brainwaves as musical notes — the low-frequency waves are like a deeply penetrating drum beat, while the higher frequency brainwaves are more like a subtle high pitched flute. Like a symphony, the higher and lower frequencies link and cohere with each other through harmonics.

Our brainwaves change according to what we’re doing and feeling. When slower brainwaves are dominant, we can feel tired, slow, sluggish, or dreamy. The higher frequencies are dominant when we feel wired or hyper-alert.

The descriptions that follow are only broad descriptions — in practice, things are far more complex, and brainwaves reflect different aspects of different locations in the brain.

Brainwave speed is measured in Hertz (cycles per second), and they are divided into bands delineating slow, moderate, and fast waves.

Infra-low (

Infra-Low brainwaves (also known as Slow Cortical Potentials) are thought to be the basic cortical rhythms that underlie our higher brain functions. Very little is known about infra-low brainwaves. Their slow nature makes them difficult to detect and accurately measure, so few studies have been done. They appear to play a major role in brain timing and network function.

Delta (δ) Waves (0.5 TO 4HZ) — Sleep

Delta brainwaves are slow, loud brainwaves (low frequency and deeply penetrating, like a drumbeat). They are generated in deepest meditation and dreamless sleep. Delta waves suspend external awareness and are the source of empathy. Healing and regeneration are stimulated in this state, and that is why deep restorative sleep is so essential to the healing process.

Theta (θ) Waves (4 TO 8 HZ) — Deeply Relaxed, Inward-focused

Theta brainwaves occur most often in sleep but are also dominant in deep meditation. Theta is our gateway to learning, memory, and intuition. In theta, our senses are withdrawn from the external world and focused on signals originating from within. Twilight states that we normally only experience fleetingly as we wake or drift off to sleep. In theta, we dream; vivid imagery, intuition, and information beyond our normal conscious awareness. It’s where we hold our ‘stuff,’ our fears, troubled history, and nightmares.

Alpha (α) Waves(8 TO 12 HZ) — Very relaxed, Passive Attention

Alpha brainwaves are dominant during quietly flowing thoughts and in some meditative states. Alpha is ‘the power of now,’ being here, in the present. Alpha is the resting state of the brain. Alpha waves aid overall mental coordination, calmness, alertness, mind/body integration, and learning.

Beta (β) Waves(12 TO 35 HZ) — Anxiety dominant, Active, External Attention

Beta brainwaves dominate our normal waking state of consciousness when attention is directed towards cognitive tasks and the outside world. Beta is a ‘fast’ activity, present when alert, attentive, engaged in problem-solving, judgment, decision making, or focused mental activity.

Beta brainwaves are further divided into three bands; Lo-Beta (Beta1, 12–15Hz) can be thought of as a ‘fast idle’ or musing. Beta (Beta2, 15–22Hz) is the high engagement or actively figuring something out. Hi-Beta (Beta3, 22–38Hz) is a highly complex thought, integrating new experiences, high anxiety, or excitement. Continual high-frequency processing is not a very efficient way to run the brain, as it takes a tremendous amount of energy.

Gamma (γ) Waves(35 TO 42 HZ) — Concentration

Gamma brainwaves are the fastest brain waves (high frequency, like a flute) and relate to the simultaneous processing of information from different brain areas. Gamma brainwaves pass information rapidly and quietly. The most subtle of the brainwave frequencies, the mind has to be quiet to access gamma.

Gamma was dismissed as ‘spare brain noise’ until researchers discovered it was highly active in states of universal love, altruism, and the ‘higher virtues.’ Gamma is also above the frequency of neuronal firing, so how it is generated remains a mystery. It is speculated that gamma rhythms modulate perception and consciousness and that a greater presence of gamma relates to expanded consciousness and spiritual emergence.

New Trial to Test Brain Wave Stimulation as Alzheimer’s Preventative

With a new $1.8 million grant from the Part the Cloud-Gates Partnership Grant Program of the Alzheimer’s Association, researchers at Massachusetts Institute of Technology and Massachusetts General Hospital are launching a new clinical trial to test whether stimulating a key frequency of brain waves with light and sound can prevent the advance of Alzheimer’s disease pathology even before volunteers experience symptoms such as memory impairment.

“Because Alzheimer’s disease leads to neurodegeneration and cognitive decline, the best time for intervention may be before those symptoms even begin,” said Dr. Li-Huei Tsai, Picower Professor of Neuroscience and director of The Picower Institute for Learning and Memory at MIT. “We are hopeful that our safe, non-invasive approach of sensory stimulation of 40Hz gamma brain rhythms can have a preventative benefit for patients. We are very grateful to Part the Cloud-Gates Partnership Grant Program for their support in funding rigorous research to test this exciting possibility.”

In extensive testing in Tsai’s lab with multiple mouse models of Alzheimer’s, the light and sound stimulation technique, called Gamma ENtrainment Using Sensory Stimuli (GENUS), improved cognition and memory, prevented neurodegeneration, and reduced amyloid and tau protein buildups. The research showed that increasing 40Hz brain rhythm power and synchrony stimulated the brain’s immune cells and blood vessels to clear out the toxic proteins. Early results from human testing at MIT show that GENUS is well tolerated and increases 40Hz power and synchrony, just like in the mice.

The new study, conducted in collaboration with neurologist Dr. Keith Johnson at MGH, will enroll 50 volunteers aged 55 or older who show signs of amyloid protein plaque buildup in PET scans but remain cognitively normal. Experimental volunteers will receive an hour of GENUS light and sound stimulation in their homes daily for a year. At regular checkups, the team will monitor GENUS's effect on amyloid buildup via PET scans as well as other biomarkers such as tau and for changes in cognition, sleep, structural and functional MRI, and other indicators of brain function and health.

The trial will be double-blinded, randomized, and controlled, meaning that some volunteers will be exposed to non-GENUS light and sound during the trial to provide a non-treatment comparison group. To ensure that bias does not influence the results, neither the volunteers nor the experimenters will know which group's volunteers are.

References

https://picower.mit.edu/news/new-trial-test-brain-wave-stimulation-alzheimers-preventative

https://brainworksneurotherapy.com/what-are-brainwaves

The Frozen Healer - Cryotherapy

The Frozen Healer - Cryotherapy

Cryotherapy is a trend with a cult following in the recovery, wellness, and beauty industries. It can be used in combination with light therapy for better results. You may have heard people talking about it or seen celebrities or athletes posting themselves coming out of icy cold chambers on social media, but what is Cryotherapy? Why is everyone talking about it?

In its most basic form, Cryotherapy is simply the use of cold temperatures to heal the body. Using the cold to help our bodies recover from injury, inflammation, soreness, or relaxation has been used since the beginning. Putting ice on a wound or bruise, jumping in a cold lake, or taking an ice bath are basic cryotherapy forms. These methods cause stagnant blood to start moving again, promoting new blood flow, which brings healing. It is a fundamental, well-understood principle that has been widely accepted and used as a means of after the fact recovery but can be quite uncomfortable, inconvenient, and extremely inefficient compared to modern-day cryotherapy through the use of cryotherapy chambers.

Day by day

Modern-day cryotherapy lends from past cold modalities to provide a much more comfortable, convenient, and effective recovery through cryotherapy chambers. Cryotherapy chambers provide a quick, 2–3 minute private session of whole-body exposure to shallow temperatures in a dry, contained, breathable air environment. Add in some music, light therapy, and awesome fog from the cold, and it becomes a fun experience that completely distracts from how cold you just got!

The goal of true whole body cryotherapy is to expose as much skin as possible to temperatures of -166F or below for a short period of time (2–3 minutes) to create a drop in the external skin temperature of 30–40 degrees. The best way to measure this is to use an infrared temperature device before and after the session on the upper arm's back, measuring the two temperature readings' delta.

Effects of Cryotherapy

Blood rushing to the core is our body’s natural way of protecting our core organs from extreme cold. When exposed to freezing temperatures, blood rushes from our extremities to our core, creating a systemic response throughout the body that produces many benefits. Cold promotes increased blood flow, bringing fresh, oxygenated blood full of white blood cells to the body's areas that need it. Cryotherapy amplifies these positive effects and adds many more incredible benefits by activating the vagus nerve and causing vasoconstriction and vasodilation. The vagus nerve is responsible for the regulation of internal organ functions [NCBI]. The vagus nerve is activated by cold on the back of the neck and touches every major organ in the body.

Whole Body Cryotherapy is not just for extreme athletes or those with present injuries, either. The best practice is for healthy, normal adults (minors with doctors) to regularly practice whole body cryotherapy 3–5 times per week. It is important to maintain a constant cryotherapy regimen and not just use it when you feel you need it or are injured. It is a continual recovery modality that helps the body stay healthy and even resist injuries and illness.

Light Therapy — Wound Healing in Horses

Light Therapy — Wound Healing in Horses

LED light therapy is really a way to help the body heal itself. In Kaiyan, we have used specific wavelengths of light absorbed by a photo acceptor, cytochrome c oxidase, within the cell's mitochondria. The energy (photons) from the lights increases the energy within the cell, which speeds up the healing process. The lights must be specific wavelengths and must be delivered at a specific dosage. We use two wavelengths in our light therapy pads, a visible red and a near-infrared wavelength. Using both red and near-infrared lights is beneficial because different depths of tissue absorb the wavelengths. The combination of the two work in concert to provide benefits for soft tissue injuries, inflammation, ligament soreness, tendon problems, sore backs, splints, strains, stifle issues, sprains, swelling, shoulder pain, hip pain, sore backs, sore necks, salivary gland problems, wounds, cuts, scrapes, arthritis pain and for trigger points and acupuncture points. Visible red light (660nm) is absorbed by skin layers very efficiently and best for uses such as stimulating trigger and acupuncture points and treating wounds and infections. Near-infrared light (850nm) penetrates to a deeper level has been used to treat concerns of tendons, ligaments, bones, joints, and muscle.

When nursing skin wounds of horses, such as lacerations or deep abrasions, owners often seek ways to maximize healing and minimize scarring, particularly when high-motion areas are involved.

“In horses, dermal injuries can be slow to heal, cause excessive scarring, and prolong a horse’s layup. In some cases, especially wounds of the limbs, proud flesh may develop in response to exuberant healing efforts,”

Said Catherine Whitehouse, M.S., an advisor for Kentucky Equine Research.

Medical-grade honey, fly larvae, and other strategies have been tested to speed wound healing. Most recently, Swedish researchers explored the use of irradiation with light-emitting diodes (LEDs), called photobiomodulation, in jump-starting wound repair. The LED used in the study features a pulsating visible red light and near-infrared (NIR) light.

“Some research shows that LEDs stimulate wound healing and decrease swelling and inflammation. With this in mind, veterinarians were hopeful that low-level light treatment could expedite wound repair in horses,” Whitehouse explained.

In this study, researchers created two circular skin wounds on the necks of eight healthy horses. One wound was treated with a combination of red light and NIR light for 4 minutes and 40 seconds on specific treatment days during the 25-day study period. The other wound on each horse remained untreated. The researchers photographed and assessed the wounds for the degree of swelling using ultrasound.

Area and degree of swelling did not differ between treated and untreated wounds, prompting researchers to conclude that red light and NIR light had no clinically relevant positive effect on horses' wound healing.

A veterinarian should examine all significant wounds. Extensive wounds with significant blood loss or tissue damage should be considered medical emergencies.

*Michanek, P., T. Toth, E. Bergström, H. Treffenberg-Pettersson, and A. Bergh. 2020. Effect of infrared and red monochromatic light on equine wound healing. Equine Veterinary Journal. doi:10.1111/eve.13266.


Light to Manage Neuropathic Pain

Light to Manage Neuropathic Pain

Imagine that the movement of a single hair on your arm causes severe pain. For patients with neuropathic pain — a chronic illness affecting 7 to 8% of the European population, with no effective treatment — this can be a daily reality.

Scientists from EMBL Rome have now identified a special population of nerve cells in the skin that are responsible for sensitivity to gentle touch. These are also the cells that cause severe pain in patients with neuropathic pain. The research team, led by EMBL group leader Paul Heppenstall, developed a light-sensitive chemical that selectively binds to this nerve cell type. By first injecting the affected skin area with the chemical and then illuminating it with near-infrared light, the targeted nerve cells retract from the skin’s surface, leading to pain relief. Nature Communications publishes the results on 24 April 2018.

The Spicy Effect

By clipping off the nerve endings with light, the gentle touch that can cause severe pain in neuropathic patients is no longer felt. “It’s like eating a strong pepper, which burns the nerve endings in your mouth and desensitizes them for some time,” says Heppenstall. “The nice thing about our technique is that we can specifically target the small subgroup of neurons, causing neuropathic pain.”

There are many different nerve cells in your skin, which make you feel specific sensations like vibration, cold, heat, or normal pain. These cells are not affected by the light treatment at all. The skin is only desensitized to the gentlest touch, like a breeze, tickling, or an insect crawling across your skin.

Illumination vs. Drugs

Previous attempts to develop drugs to treat neuropathic pain have mostly focused on targeting single molecules. “We think, however, that there’s not one single molecule responsible. There are many,” Heppenstall explains. “You might be able to succeed in blocking one or a couple, but others would take over the same function eventually. With our new illumination method, we avoid this problem altogether.”

Touch and pain were assessed by measuring reflexes in mice affected by neuropathic pain in their limbs. Affected mice will normally quickly withdraw their paw when it is gently touched. After the light therapy, however, they exhibited normal reflexes upon gentle touch. The therapy's effect lasts for a few weeks, after which the nerve endings grow back, and gentle touch causes pain again.

The team also investigated human skin tissue. The tissue's overall makeup and the specifics of the neurons of interest appear to be similar, indicating that the method might be effective in managing neuropathic pain in humans. “In the end, we aim to solve the problem of pain in both humans and animals,” says Heppenstall. “Of course, a lot of work needs to be done before we can do a similar study in people with neuropathic pain. That’s why we’re now actively looking for partners and are open for new collaborations to develop this method further, with the hope of one day using it in the clinic.”

Parkinson's: From the Gut to the Brain

Parkinson's: From the Gut to the Brain

Margaret Jarrett was diagnosed with Parkinson’s disease eight years ago. And although she was bothered by many of the symptoms that commonly afflict people living with Parkinson’s — resting tremor, uncertain gait, and terrible nightmares — the thing that bothered her the most was the loss of her sense of smell. An avid gardener, she took great pride in her roses but being unable to inhale their perfumed scent really got her down.

“You take something like your sense of smell for granted,” Jarrett, 72, said. “You don’t realize how precious something is until it’s gone.”

Parkinson’s disease combines movement disorders, including resting tremors, muscle rigidity, impaired balance, and movement slowness. It can also cause neurological problems such as depression, insomnia, memory loss, and confusion.

Its cause is unknown, but it is associated with dopamine depletion and destruction of neurons in the brain's basal ganglia region.

The current mainstay of treatment for Parkinson’s disease involves physical therapy and medications that act to increase dopamine levels in the brain. One relatively new therapy for Parkinson’s is exposure to infrared light.

Dr. Ann Liebert, co-ordinator of photomolecular research at the Australasian Research Institute, has been exploring the idea of using infrared light to modulate the gastrointestinal tract’s microbiome in humans.

The gut’s microbiome — composing trillions of bacteria, fungi, and protozoa from hundreds of different species that normally inhabit our gastrointestinal tract — has come under increasing scientific attention over the past decade, with links being established between the microbiome and several conditions including obesity, type 2 diabetes, cardiovascular disease, and depression. Several studies have also observed that the gut microbiome is markedly altered in patients with Parkinson’s disease. Fecal microbiota transplantation can have a protective effect in animal models of Parkinson’s.

The reason for this is unknown. However, an interesting observation is that another common pathology seen in Parkinson’s disease is the accumulation of misfolded proteins, called Lewy bodies, in the brain. It has been shown that certain sensory cells of the gut contain these same proteins.

Researchers have hypothesized that abnormal forms of the protein could travel from the gut to the brain through the vagus nerve, a phenomenon observed in animal models of Parkinson’s. Further support for this theory comes from findings that people who have had a surgical vagotomy — where branches of the nerve are cut — have a lower lifetime risk of developing Parkinson’s.

“We know that infrared light can reduce Parkinson’s symptoms and offer protection to brain cells. So, we wanted to test if it could modulate the gut’s microbiome as well,” Liebert said.

Provisional results from the first half dozen Adelaide participants, including Margaret Jarrett, have been promising.

“The six patients . . . showed an increase by up to 20 percent in the favorable microbiome that is associated with obesity reduction and short-chain fatty acid production. And the bacteria associated with rheumatoid arthritis, Crohn’s disease and insulin resistance were all decreased,” said Hosen Kiat, a professor of cardiology at Macquarie University, who oversaw the trial.

“For the last three years, I haven’t been able to smell flowers,” Jarrett said. “But several weeks into the trial, I started to smell my roses, daphnes, and gardenias again, and it was wonderful.”

Another participant, Barry Weldon, 70, had a similar experience. “My sense of smell improved significantly,” he said. “One day, I walked into the house, and for the first time in a long time, I could actually smell the soup my wife was cooking.”

Ron Till, 68, had an even more dramatic improvement. “The trial gave me the ability to sleep again,” he said. “It was amazing.”

Till’s neurologist cautioned him not to get his hopes up before the trial but changed his mind when he saw the results. “He told me it was voodoo medicine and probably wouldn’t work,” Till recalled. “But after the trial, I went back for my three-monthly assessment with him, and he said to me, ‘You’re actually testing better than when you first started with me ten years ago.’”

Retired geologist Sean Kennedy, 76, also experienced an improvement in his coordination and balance. “My juggling skills have improved,” he said.

In a review published in Photobiomodulation, Photomedicine and Laser Surgery, Liebert and her co-authors acknowledge that while the exact mechanism by which light therapy alters the microbiome is unknown, there is definite potential in light therapy.

“The ability of PBM [light therapy] to influence the microbiome (if proven to apply to humans) will allow an additional therapeutic route to target multiple diseases, including cardiovascular disease and Parkinson’s disease, many of which have thus far eluded effective treatment approaches,” the paper concludes.

Kiat is excited by light therapy’s potential. “If we can create non-­invasively a metabolically healthier microbiome through this extremely cheap and easy way, then inflammatory diseases and neurodegenerative diseases should be positively influenced,” he said.

Gold Coast-based GP Mark Jeffery is a clinician who has been using lasers in his practice for more than four years. He says the research supports the use of light therapy for a wide range of diseases, including Parkinson’s, Alzheimer’s, depression, and chronic pain.

“The reality is there are no real side effects from low-level laser therapy, and it’s one of the safest treatments you can ever do,” he says.

Liebert says the promising results they have seen thus far will inform a large, double-blinded randomized control trial planned for this year. “It has the potential to apply to huge fields of medicine,” she said.

Weldon’s neurologist, Chris Kneebone, is keeping an open mind on infrared light therapy’s potential. “We all just have to wait and see what the trial results tell us,” he said.

His advice for people who wish to give it a try for their Parkinson’s? “If you want to give it a go, give it a go,” he said. “I’ve got no reason not to recommend it, but at this stage, I’ve got no reason to think it is helpful either.”

As for Jarrett, she has no doubts that infrared light therapy has helped her. She enjoys pottering around in her garden again and has more energy than she has had for a long time.

“I feel like I could take on the world again,” she said. “My garden has never looked better.”

References

https://pubmed.ncbi.nlm.nih.gov/30074108/

https://pubmed.ncbi.nlm.nih.gov/29247431/

How Intense Light can Protect Against Heart Attacks

How Intense Light can Protect Against Heart Attacks

Researchers at the University of Colorado Anschutz Medical Campus have found that intense light amplifies a specific gene that bolsters blood vessels and offers protection against heart attacks.

"We already knew that intense light can protect against heart attacks, but now we have found the mechanism behind it.”

Study’s senior author Tobias Eckle, MD, PhD, professor of anesthesiology, University of Colorado School of Medicine

The study was published recently in the journal Cell Reports.

The scientists discovered that housing mice under intense light conditions for one week robustly enhances cardioprotection, which resulted in a dramatic reduction of cardiac tissue damage after a heart attack. They also found that humans could potentially benefit from a similar light exposure strategy.

To find out why they developed a strategy to protect the heart using intense light to target and manipulate the function of the PER2 gene, which is expressed in a circadian pattern in the part of the brain that controls circadian rhythms.

By amplifying this gene through light, they found that it protected cardiovascular tissues against low oxygen conditions like myocardial ischemia, caused by reduced oxygen flow to the heart.

They also discovered that the light increased cardiac adenosine, a chemical that plays a role in blood flow regulation.

Mice that were blind, however, enjoyed no cardioprotection indicating a need for visual light perception.

Next, they investigated whether intense light had similar effects on healthy human volunteers. The subjects were exposed to 30 minutes of intense light measured in lumens. In this case, volunteers were exposed to 10,000 LUX, or lumens, on five consecutive days. Researchers also did serial blood draws.

The light therapy increased PER2 levels as it did in mice. Plasma triglycerides, a surrogate for insulin sensitivity and carbohydrate metabolism, significantly decreased. Overall, the therapy improved metabolism.

Eckle has long known that light plays a critical role in cardiovascular health and regulating biological processes. He pointed out that past studies have shown an increase in myocardial infarctions during darker winter months in all U.S. states, including sunnier places like Arizona, Hawaii, and California. The duration of the light isn’t as important as the intensity, he said.

“The most dramatic event in the history of the earth was the arrival of sunlight,” Eckle said. “Sunlight caused a great oxygen event. With sunlight, trillions of algae could now make oxygen, transforming the entire planet.”

Eckle said the study shows, on a molecular level, that intensive light therapy offers a promising strategy in treating or preventing low oxygen conditions like myocardial ischemia.

He said if the therapy is given before high-risk cardiac and non-cardiac surgery, it could offer protection against injury to the heart muscle, which can be fatal.

“Giving patients light therapy for a week before surgery could increase cardioprotection,” he said. “Drugs could also be developed that offer similar protections based on these findings. However, future studies in humans will be necessary to understand the impact of intense light therapy and its potential for cardioprotection.”

Source:

University of Colorado Anschutz Medical Campus

Journal reference:

Oyama, Y. et al. (2019) Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the Endothelium. Cell Reports. doi.org/10.1016/j.celrep.2019.07.020.


Fetuses May be Able to See More Light than you Think

Fetuses May be Able to See More Light than you Think

By the second trimester, long before a baby's eyes can see images, they can detect light.

But the light-sensitive cells in the developing retina -- the thin sheet of brain-like tissue at the back of the eye -- were thought to be simple on-off switches, presumably there to set up the 24-hour, day-night rhythms parents hope their baby will follow. University of California, Berkeley, scientists have now found evidence that these simple cells actually talk to one another as part of an interconnected network that gives the retina more light sensitivity than once thought, and that may enhance the influence of light on behavior and brain development in unsuspected ways.

In the developing eye, perhaps 3% of ganglion cells -- the retina cells that send messages through the optic nerve into the brain -- are sensitive to light. To date, researchers have found about six different subtypes that communicate with various places in the brain. Some talk to the suprachiasmatic nucleus to tune our internal clock to the day-night cycle. Others send signals to the area that makes our pupils constrict in bright light.

But others connect to surprising areas: the perihabenula, which regulates mood, and the amygdala, which deals with emotions.

Recent evidence suggests that in mice and monkeys, these ganglion cells also talk with one another through electrical connections called gap junctions, implying much more complexity in immature rodent and primate eyes than imagined.

"Given the variety of these ganglion cells and that they project to many different parts of the brain, it makes me wonder whether they play a role in how the retina connects up to the brain," said Marla Feller, a UC Berkeley professor of molecular and cell biology and senior author of a paper that appeared this month in the journal Current Biology. "Maybe not for visual circuits, but non-vision behaviors. Not only the pupillary light reflex and circadian rhythms, but possibly explaining problems like light-induced migraines, or why light therapy works for depression."

Parallel systems in developing retina

The cells, called intrinsically photosensitive retinal ganglion cells (ipRGCs), were discovered only 10 years ago, surprising those like Feller, who studied the developing retina for nearly 20 years. She played a major role, along with her mentor, Carla Shatz of Stanford University, in showing that spontaneous electrical activity in the eye during development -- so-called retinal waves -- is critical for setting up the correct brain networks to process images later on.

Hence her interest in the ipRGCs seemed to function in parallel with spontaneous retinal waves in the developing retina.

We thought they (mouse pups and the human fetus) were blind at this point in development. We thought that the ganglion cells were there in the developing eye, that they are connected to the brain, but that they were not really connected to much of the rest of the retina, at that point. Now, it turns out they are connected to each other, which was a surprising thing."

Marla Feller, the Paul Licht Distinguished Professor in Biological Sciences and a member of UC Berkeley's Helen Wills Neuroscience Institute.

UC Berkeley graduate student Franklin Caval-Holme combined two-photon calcium imaging, whole-cell electrical recording, pharmacology, and anatomical techniques to show that the six types of ipRGCs in the newborn mouse retina link up electrically, via gap junctions, to form a retinal network that the researchers found not only detect light but respond to the intensity of the light, which can vary nearly a billionfold.

Gap junction circuits were critical for light sensitivity in some ipRGC subtypes. Still, not others, providing a potential avenue to determine which ipRGC subtypes provide the signal for specific non-visual behaviors that light evokes.

"Aversion to light, which pups develop very early, is intensity-dependent," suggesting that these neural circuits could be involved in light-aversion behavior, Caval-Holme said. "We don't know which of these ipRGC subtypes in the neonatal retina actually contributes to the behavior, so it will be fascinating to see what role all these different subtypes have."

The researchers also found evidence that the circuit tunes itself in a way that could adapt to the intensity of light, which probably has an important role in development, Feller said.

"In the past, people demonstrated that these light-sensitive cells are important for things like the development of the blood vessels in the retina and light entrainment of circadian rhythms, but those were kind of a light on/light of the response, where you need some light or no light," she said. "This seems to argue that they are actually trying to code for many different intensities of light, encoding much more information than people had previously thought."
Source:

University of California, Berkeley

Journal reference:

Caval-Holme, F., et al. (2019) Gap Junction Coupling Shapes the Encoding of Light in the Developing Retina. Current Biology. doi.org/10.1016/j.cub.2019.10.025.


Light Therapy can Benefit Patients with TBI (Traumatic Brain Injury)

Light Therapy can Benefit Patients with TBI (Traumatic Brain Injury)

According to a pioneering study by researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH), light therapy is safe and has measurable effects on the brain.

Senior investigators Rajiv Gupta, MD, Ph.D., director of the Ultra-High Resolution Volume CT Lab at MGH and Benjamin Vakoc, Ph.D., at the Wellman Center led the study, which was supported by a grant from the Department of Defense (DOD) and published in JAMA Network Open September 14th.

This study is one of the first, if not the first, prospective, randomized, interventional clinical trials of near-infrared, low-level light therapy (LLLT) in patients who recently suffered a moderate brain injury. If further trials support these findings, light therapy could become the first widely-accepted treatment for this type of injury.

TBI is the leading cause of traumatic injury worldwide, and an estimated 69 million people experience such an injury every year. However, there are no treatments for this condition yet, largely because the underlying biological mechanisms are not well understood. It is so challenging to do studies with actual patients in the acute stage of trauma.

"The Gulf War put TBI in the headlines because body armor had been greatly improved by then. But there were still brain injuries caused by the shock waves from high powered explosives.”

Rajiv Gupta, MD, PhD, Director, Ultra-High Resolution Volume CT Lab

For various reasons, the number of TBIs has increased around the globe since then, but effective treatments are still sorely needed. For this study, a special helmet had to be designed specifically to deliver the therapy, an undertaking that required a mix of medical, engineering, and physics expertise.

This multidisciplinary team included Gupta, a neuroradiologist, Vakoc, an applied physicist, and others specializing in developing and translating optical instrumentation to the clinic and biologic laboratories. Both Gupta and Vakoc are also associate professors at Harvard Medical School.

“For this study, we designed a practical, near-infrared treatment based on Wellman Center research and working directly with DOD on the vexing problem of TBI, a condition faced by so many,” says Rox Anderson, MD, the center’s director.

Another challenge was optimizing the wavelength of the near-infrared LLLT.

“Nobody knows how much light you need to get the optimal effect,”

explains Lynn Drake, MD, one of the study co-authors and director of business development at the Wellman Center.

“We tried to optimize the wavelength, dosing, timing of delivery, and length of exposure.”

This was done through a series of pre-clinical experiments led by Anderson. These included multiple preclinical studies led by Michael Hamblin, Ph.D. Anderson and Hamblin are both co-authors of this paper.

Near-infrared LLLT has already been considered for multiple uses, but to date, few if any studies of this technology have been tested and none in patients with TBI.

It has been studied in stroke patients, and Wellman's basic laboratory research suggests it is neuroprotective through a mechanism mediated by specialized intracellular organs called mitochondria. It took several years of research at Wellman to understand the basic mechanism before the clinical trial.

The randomized clinical trial included 68 patients with moderate traumatic brain injury who were divided into two groups. One group received LLLT via the special helmet, which delivered the light. Patients in the control group wore the helmet for the same amount of time but did not receive the treatment.

Vakoc’s team at Wellman designed the helmet. During the study, the subjects’ brains were tested for neuron activity using quantitative magnetic resonance imaging (MRI) metrics, and the subjects also underwent neurocognitive function assessment.

MRI was performed in the acute (within 72 hours of the injury), early subacute (2–3 weeks), and late subacute (approximately three months) stages of recovery. During each visit and at six months, clinical assessments were performed using the Rivermead Post-Concussion Questionnaire, with each item assessed on a five-point scale.

Twenty-eight patients completed at least one LLLT session, and none reported any adverse reactions. Also, the researchers found that they could measure the effects of transcranial LLLT on the brain.

The MRI studies showed statistically significant differences in myelin's integrity surrounding the neurons of treated patients versus the control group. Both these findings support follow-up trials, especially since there are no other treatments for these patients.

The study also showed that light does impact the cells. While it is well established that cells have light receptors, “going into this trial, we had several unanswered questions such as whether the light would go through the scalp and skull, whether the dose was sufficient, and whether it would be enough to engage the neural substrates responsible for repair after TBI,” says Gupta.

It’s important to note, and he adds that for this initial study, the researchers focused on patients with moderate traumatic brain injury. That helped ensure their study could have statistically significant findings because patients in this category are more likely to demonstrate a measurable effect.

“It would be much more difficult to see such changes in patients with mild injuries, and it is quite likely that in patients with severe brain injuries, the effect of light therapy would be confounded by other comorbidities of severe trauma,”

says Gupta.

He adds that researchers are still very early in the development of this therapy. It is unknown if it could be applied to other types of brain injury, such as chronic traumatic encephalopathy (CTE), which has received a lot of public attention over the last few years.

CTE is a progressive degenerative disease associated with a history of repetitive brain trauma such as that experienced by certain athletes, most notably football players.

This study opens up many possibilities for the broader use of photomedicine. “Transcranial LED therapy is a promising area of research, with potential to help various brain disorders where therapies are limited,” says Margaret Naeser, Ph.D., a prominent researcher in photomedicine and research professor of Neurology at Boston University School of Medicine. She was not affiliated with this particular study.

Source:

Massachusetts General Hospital

Journal reference:

Longo, M, G. F., et al. (2020) Effect of Transcranial Low-Level Light Therapy vs. Sham Therapy Among Patients With Moderate Traumatic Brain Injury. doi.org/10.1001/jamanetworkopen.2020.17337.

Light Therapy Clinical Trial Aims to Accelerate Recovery from COVID-19

Light Therapy Clinical Trial Aims to Accelerate Recovery from COVID-19

Ontario is a known leader in conducting innovative clinical trials, and the clinical trials community in Ontario has proven this strength throughout the COVID-19 pandemic. One innovative trial underway in Ontario is Vielight Inc.’s COVIDlight trial, which tests whether the recovery of COVID-19 patients may be accelerated by the use of a specialized light therapy device. This trial was made possible in part by Clinical Trials Ontario’s Trial Site Network through a connection made between Vielight Inc. and Impact Clinical Trials. CTO spoke with representatives from Vielight and Impact Clinical Trials about their trial and their experience with the Trial Site Network.

Light Therapy Device for the Treatment of COVID-19

Vielight Inc. has developed a compact and portable device named the “Vielight RX Plus,” based on the science of photobiomodulation (PBM). PBM uses certain light energy to modify cellular functions and can play a role in the management of COVID-19. This clinical trial assesses the efficacy of the Vielight RX Plus to reduce symptom duration and severity in patients suffering from COVID-19.

The Vielight RX Plus device delivers light therapy to the sternum and the nasal canal.

“This device brings a holistic approach to the treatment of COVID-19 patients,”

said Nazanin Hosseinkhah, Research Scientist and Physicist at Vielight Inc.

“The device stimulates the thymus gland, creates nitric oxide, increases natural killer cells, acts as an anti-inflammatory therapy, and increases cellular energy.”

This unique, at-home study has the potential to modulate immune cell and cytokine activity in COVID-19 patients with an easy to use the device.

“We are very hopeful that this trial will prove to help patients recover from COVID-19 at home, and result in less burden to the healthcare system,”

said Hosseinkhah.

Clinical Ttrial

This randomized controlled trial, being managed by Impact Clinical Trials, is actively recruiting 280 participants who are confirmed to have contracted COVID-19. The trial was authorized by Health Canada in early September and is recruiting participants in Ontario and the United States. Participants are allocated into a treatment or a control group, with 140 participants randomized to receive the Vielight RX Plus device and the other 140 participants receiving the current standard of care. The trial is conducted remotely with non-hospitalized participants.

Participants in the treatment group receive the device by courier within 24 hours of registering for the trial. They are asked to place the device on their chest and onto their nostril for 20 mins each day. They then track their symptoms within a daily survey over a 30-day period.

“This is a simple, at-home study for participants to be involved in,”

said Andrea Berk from Impact Clinical Trials.

“Participants in both the treatment and the control groups are completely supported throughout the trial, with a 24-hour number they can call if they have any questions.”
Connections

This trial was made possible in part by a connection made directly through CTO’s Trial Site Network.  The Trial Site Network, part of CTO’s Industry Concierge program, comprises more than 230 sites. The Network allows CTO to provide warm introductions to Ontario’s hospitals, research institutions, private research networks, and CROs.

“We have been able to guide companies such as Vielight in getting their trials up and running in Ontario,”

said Andrew Haller.

“I was introduced to Andrew Haller from CTO a few months before the COVID-19 pandemic,”

said Berk.

“Pre-COVID I was working on half a dozen connections that had been made through the Trial Site Network. When COVID-19 hit, those projects were put on hold. I reached out to Andrew to let him know Impact Clinical Trials had the consulting capacity, and that is when he introduced us to Vielight.”

Haller knew that Vielight had been searching for someone to take on the management of their clinical trial. “When Andrew introduced us to Andrea Berk from Impact Clinical Trials, we immediately connected and knew they were the right fit,” said Hosseinkhah.

The Bright Hope for Allergic Rhinitis

The Bright Hope for Allergic Rhinitis

As the name suggests, Allergic rhinitis (also known as hay fever) is an inflammatory disorder of the nasal mucosa, which occurs when the immune system overreacts to allergens in the air. This might sound small, but it affects 20% of the adult population and up to 40% of children.

Allergic rhinitis is biologically associated and equated with decreased learning, performance, productivity at work and school, and reduced life quality. It affects the quality of life, including fatigue, irritability, memory deficits, and depression. It is reflecting the social-economic costs and the negative impact on the quality of life.

Light Therapy for Rhinitis

If we talk about the current therapeutic options like allergen avoidance, medication, and immunotherapy, they are quite far from ideal. Light therapy has been treating immune-mediated dermatological conditions, e.g., psoriasis and atopic dermatitis.

Light Therapy has been There!

It is one of the oldest treatments that has been practiced in ancient times. Red light therapy has profound immunosuppressive effects on the human body.

As per ARIA guidelines, Red light therapy has been recommended for patients with allergic rhinitis who do not respond to standard medical treatment.

Now, the questions arise what the benefits of red light therapy are? Why should you opt for it?

Well, there are many benefits to using red light therapy:

  • Better and increased blood circulation in the nasal tissues
  • Enhanced local blood oxygen saturation
  • Reduced nasal obstruction (congestion) caused by nasal swelling
  • Improved nasal anti-virus ability
  • Repaired local blood capillaries
  • Strengthened detoxification ability of the nasal mucosa
The Mechanism

Light therapy treatment delivers light to pathological areas to promote tissue regeneration, reduce inflammation, and relieve pain. This treatment improves the nasal obstruction caused by Allergic rhinitis. The sessions involve illuminating the nasal cavity through specific wavelength log light ((660nm — 810nm) to the nose for a certain amount of time.

Most light therapy devices include one or two small LED light-emitting probes, which quickly stimulate the nasal cavity's blood capillaries.

Light therapy mechanisms reduce the number and function of dendritic cells and induce immunomodulatory cytokines like IL-10. Cytokines are a large group of proteins, peptides secreted by specific cells of our immune system. The Red Light therapy generates little heat, modulating mucosal blood supply and histamine release (organic nitrogenous compound involved in local immune responses). This heat alters mucosal blood supply.

The therapy shows improvement in the symptoms of nasal congestion and a decrease in nasal resistance. Studies showed that Phototherapy resulted in a significant improvement of clinical symptoms for nasal itching, rhinorrhea, sneezing, and total nasal score.

Red light therapy resulted in a remarkable improvement of clinical symptoms for nasal itching, rhinorrhea, sneezing, and total nasal score.

Adopt light therapy and give your life a better quality. Improve the shape of your life; let the negativity and obstructions be at bay!

References:

Half a Trillion-Dollar Market  —  Men.

Half a Trillion-Dollar Market  —  Men.

There’s an emerging disruptor in the beauty industry as companies target a different consumer type to expand the half a trillion-dollar market — men.

Across the globe, men’s adoption of beauty use is already starting to take off. But the trend comes in many different shapes and forms. For beauty companies struggling to find new avenues of growth, it’s a huge opportunity to see whether men are looking for traditional grooming products, discreet moisturizers, beauty balms, or popular light therapy.

According to Allied Market Research, the men’s personal care industry is predicted to hit $166 billion by 2022. According to market researcher NPD Group, just last year, men’s skin-care products alone saw a more than 7% jump in sales and with the category currently valued at $122 million.

“In recent years, the notion that men can’t or shouldn’t be using skin-care products or caring more in general about all aspects of their appearance has been receding,”

Said Andrew Stablein, a research analyst at Euromonitor International, in a research note.

The success of digitally native brands catered directly to men such as Harry’s and popular subscription service Dollar Shave Club reveal

“the average men’s grooming routine isn’t about just shaving, but can be aided by using skin-care products,”

Stablein said.

Even high-end designers like Chanel have jumped on the trend, launching its first made-for-men skincare and cosmetics line known as “Boy De Chanel” last September.

“It seems that mass players are trying to expand their market and gain share in a slowing market by growing their user base,”

Said Alison Gaither, beauty and personal care analyst at Mintel.

This includes tutorials from U.K. makeup artist Charlotte Tilbury and Rihanna’s Fenty brand, which have both put out instructions for guys who want to use makeup subtly for a more groomed appearance.

According to Coresight Research, the Asia Pacific market is now one of the fastest-growing regions for men’s grooming and cosmetic product use. Jason Chen, general manager for Chinese online retail site Tmall, told Coresight that “supply cannot meet the demand for male make-up products across China.”

However, recent data suggests the new generation of beauty consumers prefer a non-binary approach altogether. According to NPD’s iGen Beauty Consumer report, nearly 40% of adults aged 18–22 have shown interest in gender-neutral beauty products and holistic products.

“There are so many … [people] growing up with the idea that you’re not tied to the gender you’re born with,”

Said Larissa Jensen, a beauty industry analyst at NPD.

“Beauty is no longer what you’re putting out as ‘ideal beauty.’ Beauty can be anything, anyone, and any gender.”

In 2016, shortly after Coty acquired CoverGirl, the brand made history with its first-ever “CoverBoy” featuring popular YouTube makeup artist James Charles.

Charles recently found himself in a very public spat with Tati Westbrook, another YouTube beauty vlogger. Coverage of the feud, which began after Charles backed a vitamin brand that was a rival to Westbrook’s own, has been widespread and shows the influence these internet personalities have and how the business has evolved over the past two years.

While Charles may be having his struggles now, as he has lost millions of subscribers, the attention he originally received from CoverGirl sparked similar collaborations by major brands including L’Oreal, who featured beauty blogger Manny Gutierrez, known under the moniker Manny MUA, as the face of its Maybelline Colossal mascara campaign in 2017.

“I think a lot of people misconstrue a man wearing makeup as someone that is transgender or someone that wants to be a drag queen, but it’s not that,”

Guitterez, founder and CEO of Lunar beauty told CNBC.

“I think right now people are still intimidated by the aspect of it.”

Gutierrez’s makeup tutorials and product reviews have attracted nearly 5 million subscribers to his YouTube page. According to a note by the NPD Group, one setting powder product saw a 40% surge in sales after Gutierrez promoted it on his YouTube channel.

“It’s all about inclusivity and encouraging people to be a little more inclusive with both men and women,”

Said Gutierrez.

“I think that as time progresses and you see more men in beauty, it’ll get a little bit better and better.”



What You Need to Know About Red Light Therapy and Homeostasis

What You Need to Know About Red Light Therapy and Homeostasis

Our bodies are in constant need of replenishing our cells with oxygen, nutrients, and ATP energy to stay on top of our day to day activities. Also, the optimal function of our cells boils down to maintaining the balance that our body needs. This is also known as homeostasis.

Homeostasis Defined

The scientific definition of homeostasis is in a state of equilibrium, wherein the body’s chemical and physical processes are stable. The balance of the body is dependent on a plethora of factors, such as body temperature, calorie intake, level of blood sugar, the balance of fluid, and pH levels.

These factors are constantly changing and require regulation. They also adapt to changing environments like temperature, light, and activities. Reaching homeostasis requires balance for the body to reach its optimal state. This is present in humans' biology and animals' biology because it determines physical and mental performance, even stress response.

Homeostasis in Cellular Energy

The mitochondria break down food and oxygen to produce ATP energy for the body during the cellular respiration process. Healthy light intake is important in cellular energy to stimulate the mitochondria and efficiently produce ATP energy without inflammation and oxidative stress that may disrupt the cellular respiration process. Red and NIR light therapy enhances cellular and mitochondrial function to ensure that the cellular respiration process works efficiently.

Homeostasis in Body Temperature

Our bodies respond to changes in external temperature through sweating and shivering. These internal temperature processes regulate the body to maintain a temperature balance. The normal body temperature is about 98.6 degrees Fahrenheit. When the body is at a normal temperature, it’s easier to perform well. It can also indicate homeostasis and balance in the body, which we naturally try to achieve. On the other hand, experiencing a fever or being exposed to the cold can make it hard to function well for a long time.

Homeostasis and Calcium Levels

The body’s calcium is usually found in the bones and teeth, but the calcium in the blood requires constant maintenance at about 10 mg/dL. Calcium is essential for blood circulation, coagulation, and bone mineralization. When calcium is low, you may suffer from an irregular heartbeat and other health risks. Meanwhile, when calcium is high, the body may feel exhausted and sluggish because of the nervous system's inactivity. Skeletal, endocrine, and digestive systems in the bodywork hand in hand to maintain basic calcium homeostasis and balance.

Imbalance in the Body

The natural and continuous goal of the body in homeostasis, but many factors are at play. When we use our digestive, respiratory systems, and all the other organs, we need the necessary energy to process nutrients from food, oxygen, and light. The bodily systems are interdependent with one another and need each other to maintain balance.

When one system is lacking, the body naturally compensates by getting from another system to maintain balance. An example is a homeostasis in calcium levels in the bloodstream, which relies on food intake. If the diet lacks calcium, the body gets calcium from the bones, which technically regulates the calcium needed in the bloodstream, but eventually, it will make the bones weak and brittle.

The resourcefulness of the body to shift functions is a great deal. Still, in the long run, it may lead to serious health problems, possibly building up deficiencies and difficulties over time. It is imperative to be aware of the body’s balance and how diet, exercise, and light exposure are interconnected.

Healthy Light’s Effects on Biological Balance and Good Health

Light empowers the cells and enhances the cellular respiration process, creating ATP energy more efficiently. Aside from being essential for our life on earth, having enough light intake is an indication of biological balance. In fact, not getting your regular dose of sunlight may result in inflammation, sluggishness, off circadian rhythms, and poor sleeping habits. Most of the time, people don’t get enough light from their environment since they stay indoors and are surrounded by artificial light.

Being indoors is not how bodies are designed. We are programmed to thrive when our cells intake a good amount of healthy light. Not enough sunlight exposure can make the body imbalanced and lead to decreased energy production and Vitamin D.

Red Light Therapy and Homeostasis

You must be intentional in spending time outdoors to ensure that your body gets the amount of healthy light it requires. However, given the circumstances and limitations that we have, most people really do not get enough natural light, which red light therapy can solve.

Red light therapy is a non-invasive treatment that delivers red and NIR light wavelengths to the skin and cells and helps the mitochondria in cells produce enough ATP energy. Red light therapy helps keep the body and cells balanced, giving enough energy and power to the body even if there’s not enough light in the environment.

Final Thoughts

Our bodies function better when we reach biological balance or homeostasis. A balanced cellular environment indicates good health, and getting healthy light is an important variable to biological balance, on top of exercise, diet, and sleep. Red light therapy helps promote homeostasis and improve overall health by supporting a more efficient cellular environment. Red and NIR light wavelengths stimulate the mitochondria, producing more ATP energy that empowers the body.

If you want to read more about red light therapy and its benefits, you may go to our red light therapy blog. On the other hand, if you want to see our red light therapy devices breakdown, please don’t hesitate to browse through our catalog.

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How Effective is Blue Light Therapy for Spider Veins?

How Effective is Blue Light Therapy for Spider Veins?

Medical spas often recommend Blue light therapy for spider veins because they don’t have to be administered by trained doctors. And, yes, after several expensive sessions, you might start seeing a difference. The most effective method to treat spider veins is Sclerotherapy. We’ll also discuss the benefits of using Sclerotherapy is an effective alternative.

What are Spider Veins?

Before discussing how to treat spider veins with blue light therapy or sclerotherapy, we need to discuss what causes spider veins.

Spider Veins, scientifically called Telangiectasias, are a small network of blood vessels visible just under the skin's surface. They are called “spider veins” because they look like red spider webs.

Spider veins generally occur on the legs, feet, thighs, and face. They can also cause slight pain and discomfort.

Causes and Dangers of Spider Veins

While spider veins aren’t dangerous in and of themselves, they can indicate underlying vein disease.

Vein Disease, also known as Chronic Venous Insufficiency, is a disease in which the valves in the veins malfunction. The valves are usually supposed to act as one-way doors and facilitate blood flow to the heart. However, when they malfunction, blood flows back down and pools around the legs. This can put pressure on the veins and lead to spider veins or varicose veins.

While spider veins themselves aren’t dangerous, vein disease is hazardous and needs to be treated immediately. If left untreated, venous insufficiency can result in bleeding, skin infections, and ulcers.

In the worst-case scenario, vein disease can also lead to Deep Vein Thrombosis, a medical condition in which blood clots in the veins. If the clotted blood breaks, it can get carried to the lungs, leading to a potentially fatal condition called Pulmonary Embolism.

What is Blue Light Therapy for Spider Veins?

Blue Light Therapy for spider veins is a method in which blue light or laser is used to treat spider veins. The laser is non-UV in nature and emits photons that generate heat. The heat can destroy the damaged blood vessel over time. As such, the damaged vein shrinks and eventually dissolves.

Advantages of Blue Light Therapy for Spider Veins

The only time that blue light therapy for spider veins has an advantage over sclerotherapy is when it comes to the foot or face.

Both the face and the foot are dense with venous-arterial connections. When using Sclerotherapy, the Sclero has to be injected into the veins. Injecting it into the arteries can be dangerous. Most conservative physicians prefer not to use Sclerotherapy for spider veins in the face or foot.

As such, it’s better to go for blue light therapy for spider veins in the face or foot.

Sclerotherapy: An Alternative to Blue Light Therapy for Spider Veins

Sclerotherapy is the most effective and permanent method to treat spider veins. It is a minimally-invasive procedure in which a medicine called Sclerosant is injected into the damaged vein.

The Sclerosant inflicts some chemical damage to the veins, which leads to the vein walls sticking together and eventually closing up. The blood is then routed to healthier veins, and the damaged vein eventually gets reabsorbed.

Advantages of Sclerotherapy for Spider Veins

There are multiple advantages of using Sclerotherapy to treat spider veins:

  • The process is minimally-invasive and non-surgical in nature.
  • Sclerotherapy doesn’t hurt or cause much discomfort.
  • It works immediately, and you don’t need to come back for multiple treatment sessions.
  • It can get rid of spider veins permanently.
  • The entire process takes just about 30 minutes.
  • You can resume your daily activities immediately after.
  • It is cheaper than Blue Light Therapy.


Red Light Therapy Can Help Reduce Inflammation

Red Light Therapy Can Help Reduce Inflammation

We can usually identify inflammation when we see it. The inflamed part of the body looks red and swollen, and it feels hot and painful. But in this article, we’ll find out why we experience inflammation, as well as its causes, risk factors, and how red light therapy devices can help reduce it.

What Really is Inflammation?

Inflammation is our body’s natural response to pain, irritation, damaged cells, exposure to germs, and potential danger. There are two types of inflammation:

1. Acute inflammation

This type of inflammation happens as our body’s healthy response to injury or stress. We mean “healthy” because it helps the body recover faster. The inflammation happens only for a few hours and then starts to repair the damaged tissue.

2. Chronic inflammation

On the other hand, chronic inflammation can be excruciating and may cause discomfort or inconvenience. It causes an imbalance in the body, making it operate inefficiently over time. Chronic inflammation can be caused by viral infections, repetitive tissue damage, autoimmune reactions, and persistent and recurring acute inflammation. At its worse, this type of inflammation may lead to more serious diseases and/or conditions such as cancer, stroke, depression, and heart disorder.

Common Causes of Inflammation

Anything that causes stress on your body may lead to inflammation. These include:

  • Bruises
  • Bumps
  • Burns
  • Chemical irritants
  • Dehydration
  • Diseases
  • Excessive alcohol
  • Infection
  • Irritants
  • Poor nutrition
  • Poor sleep
  • Splinters
  • Toxin exposure
  • Wounds and injuries

Signs of Inflammation

There are five common signs of inflammation:

  • Heat on the inflamed area
  • Loss of function (i.e., you can’t move your arms or legs)
  • Pain
  • Redness
  • Swelling
Treatment Options for Inflammation

For acute inflammation, doctors normally recommend nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and paracetamol. Meanwhile, chronic inflammation may also be prescribed with NSAIDs, along with steroids and supplements.

However, these common treatment options help prevent inflammation symptoms but do not deal with the root cause, including improper cellular function, biological imbalance, and damaged tissues. This is also why lifestyle changes (improved diet, regular exercises, and high-quality sleep) and red light therapy could be of great help.

How Red Light Therapy Works Against Inflammation

Red light therapy, also referred to as low-level laser therapy (LLLT) or photobiomodulation (PBM), is a non-invasive treatment option. This kind of therapy delivers wavelengths of red and near-infrared (NIR) light to your skin and cells for multiple benefits. When it comes to inflammation, it can help cut down oxidative stress and activate protective cellular mechanisms to boost your immune system and protect you from diseases that may cause inflammation. It can also boost the generation of healing agents and antioxidants in the body to speed up damaged tissues' healing process.

Red light therapy can give your body the light exposure needed to function more efficiently, improve blood flow, and limit inflammation.

Conclusion

Inflammation is a natural part of our biological processes, but chronic cases may also lead to serious health risks that can affect the quality of your life. Therefore, if you’re experiencing signs of inflammation, regardless if it’s acute or chronic, please schedule an appointment with your doctor to get the care and treatment you need as early as possible.

In the meantime, to protect your body from the stress that may cause inflammation, you can do red light therapy either through a health provider or from the comfort of your home. If you need to purchase red light therapy devices, you can browse through our catalog to see the brands and products that we offer.


Red Light Therapy for Enhanced Cellular Function

Red Light Therapy for Enhanced Cellular Function

The one thing we have in common with animals, plants, and other living organisms is that we are all made of tiny little cells. The intricate human body in itself houses trillions of cells. Without cells, there wouldn’t be any life on Earth at all.

In this article, we discuss cellular anatomy and cellular function. Here, we understand how light plays a role in the support and acceleration of cellular respiration.

What is a cell?

Think of cells as the basic building block of all living organisms. As the smallest unit of life, cells contain many parts, each with a different and specific function. The command center of the cell is called the nucleus that contains the human DNA.

As these cells combine to form into an organism, they become responsible for vital activities like nutrient intake, energy production, structure building, and hereditary material processing. They make sure that your body gets enough energy and nutrients to function 24/7.

What is ATP?

One essential activity that our cells do for us is by taking in oxygen and nutrients to fuel body energy. This energy unit that is converted by the cells is called Adenosine Triphosphate (ATP) Energy.

The ATP itself is a molecule packed with high energy that empowers cellular function. ATP is required by the body to do every activity. Other cells that do more strenuous activities like muscle cells would need more ATP than others. The ideal optimal cellular function would allow cells to produce and use enough energy to achieve body balance or homeostasis.

How is ATP produced?

The mitochondria are the powerhouses of the cell. They are responsible for the production of ATP. Aside from cellular energy, this double-membrane powerhouse does protein synthesis, cell signaling, and cell apoptosis. ATP is produced with oxygen (aerobic) or without oxygen (anaerobic), the former being more beneficial because it converts more energy. Thus, 95% of cellular energy goes through an aerobic process.

Our cells go through a process called Aerobic cellular respiration to convert oxygen, food, and water into the body’s energy currency, which is ATP. This process is a well-organized metabolic pathway that consists of four stages. Our bodies take in nutrients from the food we eat for the first two stages to convert them into carbon compounds. Then for the next steps, these carbon compounds are transformed into the energy that our cells use.

How does light therapy support cellular function?

Light can sometimes be less attributed to improve our body’s physiology. However, light has benefits that go beyond aesthetic and technological purposes. Just like how light plays a role in plants' photosynthesis, it also benefits human cellular function.

Red light therapy from Kaiyan Medical composes of Red and Near-Infrared Wavelengths that aid in the Mitochondria's function to produce more ATP energy. It works by increasing the number of Mitochondria in our cells and by boosting their function.

The electron transport chain heavily governs the cellular respiration process. Red Light therapy has photons that can boost the mitochondria to function better through the Cytochrome C Oxidase. It plays an essential role in the cellular respiration process by improving the cell's electron transfer process. In this way, more ATP can be produced by the body for an enhanced cellular function.

As mentioned earlier, oxygen plays an essential role in the cellular respiration process. The infamous Nitric Oxide can take the rightful place of oxygen to limit ATP production that causes stress and cellular death. Red light therapy also gets rid of a harmful roadblock to ATP in the dissociation of Nitric Oxide and the Cox. The photons from Red light therapy prohibits the production of nitric oxide.

The effect that Red Light therapy does on our body is that by improving cellular function, our body can achieve these benefits:

  • Improved blood Flow
  • Increased Energy Build up
  • Enhanced Healing Response
  • Reduced Inflammation
  • Reduced Stress
  • Balanced Cellular Function

As you do daily activities such as eating, drinking, walking, or working out, think of the massive role that your cellular system plays to make these activities possible. In this way, you can put conscious efforts into improving your cellular system through a healthy diet and lifestyle and by integrating Red Light Therapy.

References:

https://www.healthline.com/health/red-light-therapy#how-does-it-work?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215870/

https://www.medicalnewstoday.com/articles/325884

https://www.britannica.com/science/cell-biology

https://www.britannica.com/science/mitochondrion

https://www.nationalgeographic.org/media/cellular-respiration-infographic/

Improving Mental Acuity with Light Therapy

Improving Mental Acuity with Light Therapy

It’s common knowledge that as we age, our normal brain function gets disrupted. We tend to find it harder to recall information, memorize names, and respond with reason. The decline of our mental acuity causes these commonplace mental problems. Contrary to popular belief, aging is not the sole culprit for mental deterioration. Many factors, such as aging, lifestyle changes, and environmental stress, contribute to the decline of mental acuity.

As cognitive decline progresses, significant mental changes can result in disorders such as dementia, Alzheimer’s disease, and Parkinson’s disease. While these can be common aspects of life, they aren’t inevitable. Many medical experts believe that there are many lifestyle changes that you can take to prevent the degradation of Mental Acuity.

What is Mental Acuity?

Mental acuity is known as the sharpness of the mind. It involves our cognitive ability to concentrate, process, understand, reason, and memorize. On the other hand, intelligence means the extent to which our brains absorb and process a specific amount of information at a given amount of time. Mental acuity is a natural and essential aspect of our brain health and is not a measure of how “smart” we are.

Mental acuity allows us to perform daily activities effectively and efficiently. When our cognitive ability functions well, we’re more capable of doing things without damage or conflict.

What are the symptoms of a Deteriorating Mental Acuity?

Some signs of a deteriorating cognitive ability may be subtle. However, when left untreated could progress over time to more serious mental disorders. According to the National Institute on Aging, 8 out of 10 people who experience amnestic mild cognitive impairment develop into having Alzheimer’s disease.

Here are some early symptoms of a deteriorating mental acuity:

  • Absent-mindedness and having trouble concentrating
  • Forgetfulness of specific details like names, dates, events, and facts
  • Inability to reason and make vital decisions
  • Difficulty in retrieving information
  • Memory loss
  • Difficulty in following simple instructions

How to Improve Mental Acuity

Prevention is better than cure when it comes to developing chronic brain disorders. Here’s how you can take your brain health into your own hands by observing these lifestyle habits:

  1. Ensure a well-balanced diet

Getting enough nutrition is the key to ensure mental sharpness. Making sure you eat a well-balanced diet can help your body supply enough nutrients to your brain. Omega 3 Fatty Acids are essential nutrients that help build and restore brain cells. The brain also needs antioxidants to prevent inflammation.

Excessive intake of toxins such as alcohol and drug can depreciate your mental ability. Experts agree that poor gut health also results in a weakened immune system. As a result, it weakens your body’s inflammatory response. A poor inflammatory response causes mental disorders such as schizophrenia and dementia.

  1. Have Enough Sleep

Irregular sleep patterns and sleep deprivation disrupt your body’s circadian rhythm that can lead to short-term mental problems as well as long-term chronic health problems.

Your body’s circadian rhythm is a natural body clock that controls your sleep-wake schedule as well as your digestive patterns. When you’re sleep-deprived, these rhythms get disturbed. As a result, you experience headaches, mood swings, and difficulty to focus and recall information. Aside from these unwanted effects, not having enough sleep also negatively impacts your overall brain health.

  1. Get Yourself Moving

Exercise isn’t just for physical and aesthetic purposes. It also affects brain function in multiple ways. When you exercise, your body pumps more oxygen into your brain through an increased heart rate. Exercise allows your body to release hormones that are vital in nourishing your brain cells. It also promotes growth factors in your brain to assist in the growth of neuronal connections.

A study at the University of Georgia shows that a 20-minute exercise daily can improve memory retention and information processing. Many experts agree that a sedentary lifestyle may accelerate your way into cognitive decline.

  1. Use Red Light Therapy

Red Light therapy is a more modern approach to non-invasive and low-risk medical treatments. It is a form of photobiomodulation that allows light to change human cells' physiology that causes a wide range of benefits such as biological balance and cellular energy.

Kaiyan Medical is one of the pioneers of Red light therapy that uses red wavelengths to deliver benefits to the skin and near-infrared lights to penetrate deeper within the skin’s surface. This dual technology allows for better absorption and effectiveness of the benefits of Red light therapy.

As near-infrared wavelengths penetrate the brain’s cellular system, it promotes energy production by stimulating the mitochondria. It also prevents stress by keeping away oxidative stress. Thus, it delivers multiple benefits such as better blood flow, faster cell regeneration, and improved healing.

A study shows that red light therapy has significantly improved brain function when given to patients with cognitive dysfunction. All these benefits are vital in promoting and maintaining a healthy mental acuity. Red light therapy delivers all these cellular benefits to promote better sleep quality and a more balanced circadian clock.

As you maintain these lifestyle changes, you can experience a more improved brain function and better brain health. Now you can defy all odds and allow your brain to perform at its peak by having a healthy lifestyle and a balanced body.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043367/

https://www.medicalnewstoday.com/articles/324044#oily-fish

https://pubmed.ncbi.nlm.nih.gov/12595152/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403829/

https://www.healthline.com/health/mental-health/brain-exercises

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870908/


How Does Red Light Therapy Relate with Ketogenic Diet?

How Does Red Light Therapy Relate with Ketogenic Diet?

Red light therapy is an easily accessible and affordable clinical device that boosts metabolism and increases ATP energy production. It is a non-invasive modulator of metabolism that delivers proper frequency, power, and luminance by shifting the mitochondria's function organically.

Ketogenic Diet and Red Light Therapy

A ketogenic diet involves the consumption of low-carb, high-fat meals. When practiced together with red light therapy, it can amplify your metabolic flexibility. It also helps cells burn more sugar and fat efficiently. Good levels of ATP energy production (empowered by mitochondria by converting oxygen and nutrients to ATP) can help prevent high-blood or low-blood pressure conditions. The process of creating ATP energy works best when our body and cells are well-balanced, reaching a state called homeostasis.

One thing to consider in following a diet plan is over-nutrition, which may lead to metabolic inflexibility. When over-feeding happens, the production of ATP energy may result in metabolic congestion. Red light therapy can help alleviate this metabolic congestion by focusing amplification of ATP energy levels. Insulin can mediate metabolic congestion by the fluidity between glucose, fatty acids, and amino acids. An important step for ATP energy production is forming the COX enzyme, which can aid metabolism by pairing oxygen neutralized into the water with high-energy electrons.

If the COX enzyme goes out of sync with electrons' flow, the high-energy electrons won’t effectively be neutralized into water. Red light can help regulate the healthy formation of the COX enzyme, efficiently oxidizing fat. The ketogenic diet triggers cells to insulin by stimulating ATP energy production by increasing metabolic flexibility, reducing carbon combustion, and helping clear metabolic congestion.

Significance to Healing

The chemical DHEA (dehydroepiandrosterone) plays numerous vital roles in health. It helps with the metabolism of cholesterol that produces hormones such as progesterone, estrogen, and testosterone. As we age, our levels of DHEA decreases, as well as the synthesis of such hormones. Low levels of progesterone can affect women in their peri-menopausal and post-menopausal stages. This is a function of the decline in mitochondria, which then affects ATP energy levels.

Low levels of DHEA may contribute to the insufficiency of adrenaline and estrogen dominance, which is common to middle-aged women at the peri-menopausal or post-menopausal stage. Women rely on the production of adrenaline and DHEA to keep their progesterone levels and prevent estrogen dominance.

Lower production of DHEA and progesterone can be an effect of elevated secretion of cortisol that is caused by acute/chronic stress. When high levels of stress reduce the adrenal glands' proper functions due to the decrease of synthesis of the adrenal cortex steroid hormones in the mitochondria, it results in adrenal insufficiency.

Based on health professionals' studies, when cortisol levels drop, it inhibits the synthesis and secretion of DHEA/progesterone, resulting in pathophysiological changes caused by stress. Enzyme activation and regulatory signaling can affect the fluidity dynamics between cortisol, DHEA, and other hormones such as progesterone, estrogen, and testosterone.

Red light therapy and ketogenic diet can mediate inflammatory stress and regulate the healthy production of DHEA.

Estrogen Levels

Estrogen is a master regulator of female metabolism. A youthful and regulatory expression of estrogen is the production of 17B-estradiol (E2). It modulates the menstrual cycle to ensure the healthy release of the corpus luteum, which secretes progesterone.

On the other hand, progesterone helps maintain a healthy uterus lining. When the expression of E2 is sufficient, progesterone secretion also increases. Having high progesterone levels means having lower estrogen and a lesser risk of getting diseases like breast, ovary, and colon cancer. E2 also contributes to potential partition fuel, orchestrating metabolic flexibility, and increasing energy levels that lead to optimal cerebral glucose metabolism.

The decline in the peripheral steroidogenesis of E2, progesterone, and testosterone is common as time goes by.

Testosterone Levels

A 12-week ketogenic diet may increase testosterone levels in men due to an increase in cholesterol and DHEA. Red light therapy also improves the mitochondrial synthesis of testosterone from DHEA.

For males, testosterone naturally converts to E2, but healthy testosterone levels stipulate a hormonal challenge to the synthesis of E2. An enlarged prostate can be caused by estrogen dominance when there is no testosterone/estrogen ratio balance. Having healthy testosterone levels may lead to a decline of estrogen dominance, as it is for progesterone in women.

Other Healing Benefits

Healthcare professionals strongly believe that red light therapy can be a powerful healing agent that may help prevent diabetic ulcers and lower chances of extremity amputations when practiced together with a ketogenic diet.

Diabetic ulcers usually result to lower limb amputations in the long-run. Studies show that diabetic foot ulcers and lower extremity amputations are increasing in number. In fact, having unhealed wounds can be alarming as the post-amputation survival rate for people with diabetes averages to only five years. Statistics show the urgent need to prevent, detect, and prove that treatments for lower limb ulcers should be highly considered. Red light therapy has been proven to increase the circulation of blood flow and healthier skin.

Innovation

Red light therapy and ketogenic diets are considered to be disruptive innovators in the healthcare system. Apart from the fact that red light therapy is non-invasive, such treatment shows great potential in helping lengthen the lifespan and improve people's overall health. Red light therapy also promotes a more affordable and accessible treatment that can be done in the comfort of your home.

Here at Kaiyan Medical, we offer red light therapy devices to help you achieve your health and aesthetic goals. To learn more about the brands and products we offer, please click here.

More References

https://perfectketo.com/red-light-therapy/

https://perfectketo.com/keto-diet-plan-for-beginners/

https://www.rejuvcryo.com/the-science/2019/8/14/article-the-surprising-synergy-between-keto-and-red-light-therapy-rejuvcryo-north-county-san-diego

Deuterium and Red Light Therapy

Deuterium and Red Light Therapy

As the most accessible element in the globe, hydrogen plays a huge role in our biological processes. However, you may not know that hydrogen usually brings an uninvited guest in your body, and we call it deuterium. Having high deuterium levels may change the chemical reactions in your cells and affect your bodily functions and metabolism, leading to unwanted health consequences.

What is Deuterium?

Deuterium is also known as a “heavy hydrogen” and is one of the two stable hydrogen isotopes. We commonly have it in our bodies — in fact, it helps children grow. However, adults may have too much deuterium because of dietary and environmental factors. As mentioned above, this may lead to chemical reactions at a cellular level and lead to health risks.

How Can Deuterium Affect Your Health Negatively?

Hydrogen is necessary for our day-to-day bodily functions. Our biological processes require it, and we usually get it from what we eat or drink. Upon intake, hydrogen goes to the mitochondria, also known as the powerhouse of the cells.

Our mitochondria can be compared to thousands of engines that continually run to produce the ATP energy we need to survive daily. The majority of people eat only three to five pounds of food each day, but we usually make more than 170 pounds of ATP energy at the same time.

On the other hand, deuterium is like hydrogen’s “evil” sibling. And we repeat, excess deuterium is harmful to our bodies. Because it is twice as heavy and large as hydrogen, it may damage the nanomotors in your mitochondria and slow down ATP energy production. As time goes by, the wear and tear on your nanomotors caused by the heavy hydrogen atoms may completely break your nanomotors. This damage may cause muscle pain, dehydration, impaired memory, poor sleep, headaches, and lymph nodes.

How Can You Measure the Level of Deuterium in Your Body?

Two “D-terminator” diagnostic tests can help measure the deuterium levels in your body. Advanced technology, such as magnetic resonance imaging (MRI), can also be used to visualize and track deuterium patterns in your body, whether it’s in your bodily fluids, DNA, or even your hair and nails. Based on these tests, your doctor will be able to determine your deuterium levels. And when it shows to be excessive, he/she may come up with a plan to deplete deuterium in your body.

Why Do We Get Overloaded with Deuterium?

We experience high deuterium levels because of what we eat or drink and some other environmental factors. For instance, carbohydrates, processed foods, and synthetic supplements contain high levels of deuterium. Tap, ocean, and river water also have high deuterium levels, so when you’re exposed to these things regularly, you may experience an overload of this hydrogen isotope.

How Can You Deplete Deuterium?

Nutrition is the baseline of depleting deuterium. Based on your test results, your doctor may recommend consuming food groups that contain lower levels of deuterium, such as proteins, green vegetables, and healthy fats. You may also be advised to drink deuterium-depleted water to lower your deuterium levels.

Health experts say that a body that functions properly can naturally regulate deuterium levels and produce healthy amounts of ATP energy.

How Does Red Light Affect Deuterium?

Red and near-infrared light can affect our body’s hydrogen bonds in a process quite similar to photosynthesis. The water inside our cells usually becomes less harmful when our bodies absorb wavelengths of red and near-infrared light between 600–950 nanometers. This helps with proper cellular respiration and helps increase ATP energy production in your body.

Changing the water's resistance in your body, red, and near-infrared light can help reduce the amount of friction at the cellular level, promote cellular longevity, and lead to higher outputs of good energy.

To learn more about the benefits of red light therapy or to see what kind of red and near light therapy devices you can use to lower your deuterium levels, click here.


More References

https://www.nature.com/articles/s41598-020-61983-3

https://doi.org/10.1038/s41598-020-61983-3

Wang, M.; Audi, G.; Kondev, F. G.; Huang, W. J.; Naimi, S.; Xu, X. (2017). "The AME2016 atomic mass evaluation (II). Tables, graphs, and references" (PDF). Chinese Physics C. 41 (3): 030003-1–030003-442. doi:10.1088/1674-1137/41/3/030003.

https://www.hindawi.com/journals/tswj/2018/5454367/

How Saunas and Red Light Therapy are Distinct but Complementing

How Saunas and Red Light Therapy are Distinct but Complementing

Saunas and red light therapy devices are clinically-proven treatments that complement each other wonderfully, even if they depend on distinct biological mechanisms to yield various natural health and aesthetic benefits.

In this article, we’ll focus on how things work for red light therapy and the distinctions of traditional saunas, and what you can actually gain by availing of either of them.

What You Need to Know About Saunas

Saunas can make your body’s core temperature hotter by supplying sufficient heat throughout your body. It has been a part of traditional medicine for various centuries, as the old century folks realized the health benefits of sweating. Although there are multiple types of saunas, two of them are the most popular:

  1. Traditional Convection Saunas

When you think of saunas, this is the first scenario that comes to mind: hot and steamy. This type of sauna requires more energy as it delivers heat to the atmosphere, warming the air inside the sauna, and distributes heat in the body. Traditional convection saunas can maintain air temperatures between 170–200°F and are an ideal type of sauna for general use. It is important to comprehend the different temperatures required for specific health concerns since being exposed to heat more than what has required triggers a warning for unsubstantiated claims.

  1. Infrared Saunas

The latest trend in saunas is the infrared saunas. Inside, instead of warming the air, this kind of sauna heats actual objects. Such objects include those with emitting surfaces, charcoal, and carbon fiber. Infrared saunas' effectivity is directly attributed to the temperature, humidity, and length of time your body is exposed to heat, even though many saunas claim to provide “full-spectrum” infrared wavelengths.

The farther the wavelengths are in the infrared spectrum, the more they are considered efficient and effective in heat production. This will be thoroughly discussed later, but the general gist is that heat supplementation is the primary purpose of saunas, convection, and infrared.

On the other hand, near-infrared wavelengths in near-infrared saunas generate very little heat. Most of the high-quality standard saunas use more effective heats from the far-infrared spectrum or IR-C wavelengths.

What are the Health Benefits of Saunas?

Inducing thermal stress on the body is the primary function of every sauna, but what does it really mean?

One of many biological responses from sauna usage is increased heart rate as well as perspiration. The essential body processes protein metabolism and is also affected by enough heat. Heat shock proteins are a special kind of protein that responds specifically to cellular stress from heat. Heat stress induction leads to natural health benefits like those we gain doing physical activities.

One experiment had participants sat in a sauna treatment for 30 minutes at 194°F for 3 weeks, totaling 13 work sessions. The results showed that the participants improved 32% in performance tests versus those who underwent sauna treatments.

Besides improving your cardiovascular functions, using saunas can help reap benefits such as detoxication, decreased depression, and lesser chronic fatigue.

Red Light Therapy vs. Saunas

What differentiates saunas from red light therapy devices is their mechanism of action. While saunas utilize heat for biological effects, red light therapy devices supply healthy light wavelengths directly to the skin and cells. Even when producing almost no heat, red light therapy devices help with cellular function improvement and support bodily balance. Simply put, red light therapy helps energize the body with light, while saunas heat your body.

How does red light therapy work?

Mitochondria, the powerhouse of our cells, is wonderfully affected by certain wavelengths of natural light. This helps in producing energy within the cells of our body, feeding photons to our cells from natural light via red light therapy.

What about clinically-proven wavelengths?

We feel warm when exposed to sunlight and other heat sources such as fire and hot coals because most of the wavelengths, including ultraviolet (UV), are rapidly absorbed by the outer layers of the skin tissue as heat.

However, unknown to many, some wavelengths have the unique capability of boosting your cellular functions and energy. These are those few wavelengths that can penetrate human tissues more effectively, having photons power-up your “cellular batteries.”

What to Look for When Buying Red Light Therapy Devices and Saunas?

One of the first few things you need to look for in saunas is the temperature it produces. You need to consider some other factors, including the type of wood, the heating unit (Is it conventional or infrared? Is it near far or full-spectrum?), finishes and stains, price, and more.

On the other hand, some of the factors you need to consider when choosing a red light therapy device are the device’s light energy output, light color or frequency range in terms of nanometers, warranty, body or treatment coverage area, the price, and the credibility of the company provider.

Light Therapy and Saunas: Friends with Benefits

Saunas and red light therapy devices offer a wide range of natural health benefits, which surprisingly go well with each other. They both support balance and health to improve your fitness and function but do not overlap with each other’s effects because of energy supplementation in distinct forms and wavelengths. What a great combination of complementary natural therapies!

Here at Kaiyan Medical, we provide different types of red light therapy devices for various medical, wellness, and aesthetic uses. To see our list of products, click here.

References:

https://www.health.harvard.edu/staying-healthy/saunas-and-your-health

https://www.healthline.com/health/fitness-exercise/are-saunas-good-for-you

Scoon GS, Hopkins WG, Mayhew S, Cotter JD. Effect of post-exercise sauna bathing on the endurance performance of competitive male runners. Journal of Science and Medicine in Sport. 2007 Aug.

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Blue Light Therapy for Acne: Does it Work?

Blue Light Therapy for Acne: Does it Work?

Having acne-prone skin can be incredibly frustrating, especially when your oral and topical treatments don’t seem to work well enough. Skincare ingredient junkies know actives that target acne problems such as salicylic acid and benzoyl peroxide can be a few of the most irritating ingredients that you can put on your skin- especially when used in hefty amounts.

If you’ve been wallowing into these-but to no avail, you might ease your frustrations by learning about what Blue Light Therapy can do to acne problems.

What is Blue Light Therapy?

Blue Light therapy is a form of phototherapy that uses a visible light device that has been used by dermatologists for decades as a clinically proven treatment for acne.

The treatment is considered a generally safe, non-invasive, and pain-free procedure with no downtime. Besides being a popular anti-acne treatment, Blue Light therapy has also been shown to remove stubborn acne marks and sunspots. It eliminates free radicals caused by exposure to harsh environments that may oxidize and age your skin.

One significant impact of Blue light therapy is that it has been used to treat skin cancer in patients with actinic keratoses at University of Iowa Hospitals & Clinics. The American Academy of Dermatology considers Blue light therapy a promising treatment for numerous skin issues like acne.

How effective is Blue Light Therapy Work for Acne?

Blue light has been shown to have an antimicrobial effect that penetrates deep into the skin’s pores to eliminate the acne-causing bacteria, otherwise known as Propionibacterium acnes, or P. acnes. Blue Light has been proven to have an antimicrobial effect, making it an ideal treatment to effectively kill several types of bacteria in your pores and oil glands responsible for causing breakouts.

A clinical study shows that 77% of people with acne-prone skin treated with blue light therapy for five weeks have seen significant changes in their skin. Another research suggests that at-home blue light therapy has reduced acne lesions on people who have used the therapy for 28 days.

Unlike other topical treatments that address inflammation, blue light therapy targets breakout-causing bacteria in your pores and by healing the skin from within. Blue Light Therapy is a form of defensive treatment to acne by eradicating bacteria that causes redness and inflammation and a proactive solution to preexisting acne.

Who is a good candidate for Blue Light Therapy?

Experts at the American Academy of Dermatologists agree that blue light therapy works best for people who have mild to moderate acne problems. It is also a great treatment to eliminate acne scars. Blue light therapy works by addressing the acne issue from its core. It works by removing preexisting mild to moderate acne while preventing sebum build-up that causes the inflammation. Severely too deep abdominal cystic acne may benefit from other prescriptive medications that target more serious skin problems. People who incorporate Retinols in their skincare routine may also want to avoid getting Blue Light treatments as such ingredients make the skin very sensitive.

What Blue Light Devices should I use?

Although many dermatologists use current clinical studies, there are available at-home blue light therapy devices that effectively treat acne problems.

The best Blue Light Devices should be FDA- cleared, just like our Blue Lights Therapy Beauty Skin Complexion Handheld Device and Aduro Mask, that is made with medical-grade quality. FDA-cleared at-home devices have innovated into using the same technology that delivers satisfactory results for acne-related problems.

Blue Light therapy works best as a treatment for acne when used consistently. A weekly maintenance appointment to your dermatologist’s clinic for a blue light treatment may cost you $100, which makes it a much more expensive endeavor than investing in at-home devices.

Portable blue light therapy devices can be more beneficial for you as they can be used more frequently as an addition to your skincare routine at a lower price point.

The best blue light therapy devices in the market provide a safer alternative to other harsh treatments for acne that may require risks such as scarring and irritation. If you want to know more about effective light therapy treatments, check this out.

Now you can add a cool, avant-garde addition to your skincare that can be a very convenient and effective treatment for your stubborn acne problems.

References

https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/radiation/photodynamic-therapy.html
https://www.medicalnewstoday.com/articles/319254
https://uihc.org/health-topics/blue-light-therapy-warding-skin-cancer
https://www.healthline.com/health/blue-light-therapy

Putting the Light on Psoriasis

Putting the Light on Psoriasis

Psoriasis is an autoimmune inflammatory skin disease where the skin cells build up and form scales and itchy, dry patches over the surface. It is a misunderstood skin condition. The misbelief is that it not treatable and affects a particular gender or at a certain age. However, it can affect both men and women equally, and more than 5 million adults deal with this skin disorder — which is about 2% of the U.S. population.

Another common misconception is that it is contagious and can spread from one person to another. Well, Psoriasis is an immune system problem in which your immune system does not work as it should normally do.

Light Therapy: The Advanced Way

With some options available for Psoriasis, light therapy is one of the oldest, safest, effective, convenient, and highly preferred treatment by dermatologists. It has been widely used to treat stable psoriatic lesions, including different parts like the trunk, scalp, arms, and legs, and partial nail psoriasis. The treatment of light therapy is available in a variety of light with different mechanisms of action. Based on the bandwidths, the varied versions includes ultraviolet B (UVB), psoralen ultraviolet A (PUVA), pulsed dye laser (PDL), photodynamic therapy (PDT), intense pulsed light (IPL), light-emitting diodes (LED), etc.

How it Works

Light therapy has a very long history of dermatological benefits. Psoriasis happens when the skin cells there is an abnormal production of skin cells. Light therapy works by slowing down the excessive production of skin cells on the epidermis layer. This reduces plaque formation. It also reduces inflammation and limits the growth of skin cells by affecting the functioning of the DNA.

Many clinical studies and researches have displayed positive and effective result in the treatment of various types of Psoriasis like –

  • Small areas of stubborn, thick plaque psoriasis
  • Palmoplantar psoriasis (on hands and feet)
  • Nail psoriasis
  • Scalp psoriasis

Why do Dermatologists Prescribe Light Therapy?

Light therapy treatment can:

  • Slow down the growth of abundant skin cells
  • Repress the functioning of an overly active immune system
  • Reduce inflammation and allow the skin to heal itself
  • Reduce or eliminate the dry and itchiness

Light Therapy Mechanism

Light therapy can be delivered on any affected skin areas such as the hands or scalp, or across their whole body. But proper care and protection are given to the skin areas, such as the eyes and genitals, before treatment.

The treatment doesn’t work in on-go. Several sessions are required as the effect is gradually seen in patients. The treatment requires multiple sessions where the amount of light is gradually increased per session. The light exposure is not instant and varies for a different duration depending on the skin condition severity.

The sessions give proper time to heal the skin. Usually, the sessions go from two to three months. We need to understand the fact that every person’s skin reacts to light therapy differently. Hence, how much improvement one sees in their psoriasis symptoms and how long those benefits last depends totally on their system.

Now the time has changed, and technology has brought more convenience in getting the treatment. Kaiyan Medical provides you numerous products that you can use at your home and enjoy your daily activities without getting disturbed. Break the old and mainstream treatments and adopt effective light therapy to let your skin and life heal completely!

References:

The Effect of Green & Red Light Therapy on Hearing

The Effect of Green & Red Light Therapy on Hearing

Low-level laser therapy

Low-level laser therapy (LLLT) has been practiced for over 20 years in Europe and has been introduced in the United States as a treatment for pain and postsurgical tissue repair. It has been proposed that laser energy in the red and near-infrared light spectrum may aid in the repair of tissue damage. A proposed mechanism for this therapeutic effect is the stimulation of mitochondria in the cells to produce more energy through the production of adenosine triphosphate.

Studies in humans have investigated the effects of LLLT on both hearing loss and tinnitus, with equivocal results. Some studies have found an improvement in hearing thresholds and tinnitus symptoms.

The Subjects

A total of 35 adult subjects were enrolled in the study. Two subjects withdrew from the study due to loss of interest and/or scheduling difficulty. The data from three additional subjects were not included in the analysis. One subject yielded unreliable audiometric and speech understanding data, speech scores could not be obtained from one subject with a profound hearing loss, and calibration problems compromised data from the third subject. Data from the remaining 30 subjects were included in the analyses. The experimental protocol was approved by the Institutional Review Board of The University of Iowa, and written informed consent was obtained from all participants.

The Device

An Erchonia EHL laser was used to provide the laser stimulation. The device was a portable unit that consisted of a hand-held probe and a main body. The probe contained two laser diodes. One diode produced light in the green part of the visible light spectrum (532 nm wavelength), and the other diode produced light in the red part of the visible light spectrum (635 nm wavelength). Both diodes produced energy levels of 7.5 mW (class IIIb). The laser beams from both diodes were dispersed through lenses to create parallel line-generated beams, rather than spots. A second Erchonia EHL device served as the placebo. It was identical to the treatment device, except that the laser diodes were replaced with nonfunctioning standard light-emitting diodes.

The Groups

The study used three groups: treatment, placebo, and control. Subjects were pseudorandomly assigned to one of the three groups.

Initial group assignment was random with occasional adjustment to ensure that the three groups were similar in terms of number of participants, female/male ratio, mean age of participants, and mean pure-tone audiometric thresholds. The treatment group received the laser treatment protocol using the functional laser device. The placebo group also received the laser treatment protocol, but using the nonfunctioning laser device. The control group made similarly timed visits to the laboratory but received no real or feigned “treatment.” The study used a repeated-measures design, with each subject taking a battery of pretests, followed by treatment followed by a battery of posttests.

Analysis

Data were obtained from both ears of each subject. Since no obvious differences were seen between left and right ears, data from both ears were combined in the following analyses. Strictly speaking, this likely violates the statistical assumption of independent sampling, since the test results from left and right ears of a single subject are likely to be highly correlated. None of the statistical tests used in the analyses are robust to the assumption of independent sampling, and the effect of including both ears is likely to be that of artificially increasing the sample size, making it more likely that a statistically significant result will be found. All statistical tests were conducted using a significance level of .

Conclusions

No statistically significant effect of LLLT on auditory function was found, as assessed by pure-tone audiometry, speech understanding, and TEOAEs in this test. Additionally, no individual subjects showed any clinically significant change. It remains possible that other methods of LLLT could have an effect on hearing. The type of device used was not the best one for this type of study. Further research elucidating the anatomic and physiologic bases for therapeutic effects of LLLT on hearing are needed before further clinical testing is warranted.

More References

Clinical Study | Open Access. Volume 2013 |Article ID 916370 | https://doi.org/10.1155/2013/916370

ClinicalTrials.gov (NCT01820416)

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How to Prevent Jet Lag with Light Therapy

How to Prevent Jet Lag with Light Therapy

How to Prevent Jetlag with Light Therapy Treatment

Globetrotters know flying across time zones can be all fun and games until headaches start to kick in, sleep cycles get disturbed, and frequent moments of inappetence prevents them from enjoying even the most sumptuous local cuisine. If you’ve had any of these unfortunate events disturb your travel plans and work productivity, you’ve most likely experienced a jet lag.

What is Jet Lag?

Jet lag, also known as jet lag disorder is our body’s reaction to abrupt changes in new environments that are two or more time zones ahead/delayed. This can affect even the most seasoned flyers like pilots and business travelers.

What causes Jet lag disorder?

Your body has a clock system called circadian rhythm that schedules your body for its sleep and wake up time. Your circadian clock is synced depending on your original time zone.

Jet lag is caused by a temporary discoordination with your circadian clock and your new time zone or sleep-wake schedule. This is why when you expose your body to abrupt schedule changes, its normal functions related to sleep, coordination, and gastrointestinal processes are disrupted. While your mind may be ready to fly west, your body may still be stuck home and is still hours ahead.

Treating Jet Lag with Light Therapy

Jet lag can take days, weeks, or longer to improve, which may affect daily activities. In addition, although jet lag may be a temporary disorder, frequent exposure also poses significant long-term risks such as disturbances in menstrual cycle, cognitive defects, and temporal lobe atrophy.

One popular and effective treatment for jet lag disorder is Light therapy. Light therapy has been considered as a popular and effective treatment for jet lag disorder and has been backed by research since 1980.

Your body clock is largely influenced, among other factors by light, which is indicative of the rising and setting of the sun. This means that adjusting to a new time zone also means adjusting to a new daylight-night time and awake-sleep schedule.

Essentially, light therapy assists your brain and body in adjusting to a new time zone by conditioning yourself to light at an appropriate time. This allows your normal body functions to be in sync with your new schedule. By regulating light exposure, you can adjust faster with new conditions.

Studies show that exposure to light therapy helps people adjust their circadian clocks to new time zones more efficiently and effectively. Treatment of jet lag by Light therapy involves an exposure to natural or artificial light such as red light therapy.


How does Red light therapy work?

Red light therapy is a non-invasive, quick and easy treatment for jet lag that brings concentrated natural light to your body cells in order to condition it for a new day-light schedule. Red light therapy emits natural light that can boost cell energy without the putting your body at risk of the damaging UV rays from the sun.

If you travel westwards, you can use Red Light in the evening to help you adjust to a later time. On the other hand, if you travel eastwards, you can expose yourself to red light in the morning in order to acclimate your body to an earlier time zone.

Kaiyan produces high-quality Red light therapy home devices that utilize medical-grade LED (Light-emitting Diode) in order to produce a natural red light that is ideal for adjusting to new time schedules.

The great thing about this device is that, if you often work away from sunlight, this indoor light therapy device can be a convenient way to adopt your circadian clock to a new time zone. Check out our top picks for the best FDA-cleared light therapy masks.

Experiencing jet lag may be the ultimate bummer for travelling, but sufficient knowledge and proper treatment can keep you away from ruining your travel plans and goals.

References:

https://www.scientificamerican.com/article/how-to-prevent-jet-lag/
https://www.mayoclinic.org/diseases-conditions/jet-lag/diagnosis-treatment/drc-20374031
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829880/


How Music Healing Therapy Can Help Breast Cancer Patients

How Music Healing Therapy Can Help Breast Cancer Patients

What is music therapy?

According to the World Federation of Music Therapy, this term refers to the use of music and / or its elements (sound, rhythm, melody, harmony) with a patient or group of patients, in a process created to facilitate, promote communication , relationships, learning, movement, expression, organization, and other relevant therapeutic goals to meet physical, emotional, mental, social, and cognitive needs.

Music therapy aims to develop potential and / or restore the functions of the individual in such a way that he can achieve a better intra and / or interpersonal integration and consequently a better quality of life through prevention, rehabilitation and treatment.

Learn also more about sound healing and light therapy.

How does this therapy help breast cancer patients?

It was the Taipei Medical University that has developed a study that has given the following conclusion: listening to music at home reduces the severity of symptoms, the intensity of pain and the fatigue experienced by patients with breast cancer .

For the study, published in the “European Journal of Cancer Care,” 60 participants listened to music in five 30-minute sessions per week. After 6, 12 and 24 weeks, music therapy reduced the severity of symptoms, as well as the intensity of pain and fatigue. Furthermore, it instantly reduced physical and mental fatigue.

“The use of music can help the physical and psychological well-being of patients,” explained the study’s lead author, Kuei-Ru Chou. He has also recommended that home music interventions be given to breast cancer patients to reduce their negative thoughts associated with the disease.

From Medina Reeds we send a message of support to all patients who suffer from this disease and we invite everyone, patients and non-patients to apply music therapy on a day-to-day basis for all the wonderful benefits that music brings us.

References

Ref.“Hamburg, 1996, Clinical Practice Committee of the World Federation of Music Therapy”. nineteen ninety six.

https://www.sespm.es/la-musicoterapia-ayuda-a-pacientes-con-cancer-de-mama/

The Brain in Our Skin

The Brain in Our Skin

Dr. Claudia Aguirre which has a Ph.D. in neuroscience from USC and travels the world lecturing on a broad range of topics from neuroscience to skin care has been researching the power of the skin and its connection with the brain.

The skin is highly innervated and intricately connected to the brain and central nervous system, just as other sensory organs are. Dr. Claudia Aguirre is discovering that the skin has a lot of neuro potential, or neuroplasticity, that has gone unrecognized. For example, just as our eyes have receptors that transduce light photons into signals to the brain that we process as vision, we’re discovering that our skin also has light receptors. Although we don’t yet know how they work, we speculate that they might be signaling the brain to make systemic changes that affect the full nervous system. Similarly, olfactory receptors in the hair follicles, just as we do in the nose.

Examples

Another example is touch, for which our skin is the primary sense organ. Skin is also our largest organ, which gives us a clue as to how important touch is. Different receptors in the skin can tell us not only whether what we touch is hot or cold, rough or smooth. Skin can even sense the intention behind the touch. A gentle touch feels much different than an aggressive one. We can tell whether the person giving us a massage is paying attention or whether they’re distracted. Moreover, different kinds of touch elicit different biochemical and hormonal responses, which have systemic results. A hug or kiss stimulates the release of oxytocin, the bonding hormone, through the bloodstream, while a punch or shove will release adrenaline and cortisol. All of these capabilities are what we say by the hidden brain in the skin.

Nervous System

The skin is connected to the nervous system; it’s connected to the endocrine system. The skin is impacted by our emotional states and, conversely, our skin can impact how we feel about ourselves. Cultural stress and anxiety can trigger or aggravate many skin conditions—from acne to eczema to herpes, psoriasis, and rosacea. Conversely, a disfiguring skin condition can trigger stress, anxiety, depression, and even suicide. Chronic, generalized anxiety can create chronic inflammation and exacerbate inflammatory skin conditions, such as the ones mentioned previously. Chronic stress can result in chronic anxiety, hypervigilance, poor sleep, and a whole cascade of effects resulting in a constant breakdown of tissues and organs, including the skin. There’s a whole new field of medicine being developed called psychodermatology, which is the study and treatment of the psychological component of skin conditions. Better understanding of the neuropotential of skin also opens the possibility of whole new avenues of treatment with light therapy for many of our chronic conditions.

In Kaiyan Medical we have understood that neuroscience should absolutely be part of the conversation about skincare and beauty because the brain and the skin are intimately connected. Skincare is important not only for the skin, but also the brain. That's why we keep developing light therapy devices for skin and brain. In Kaiyan we always recommend to listen for all the little signs that your skin tells you that you tend to ignore. You get a rash, and you brush it off: “Maybe it’s just dry out. Maybe I need to switch creams.” But if it occurs repeatedly, you need to look more closely and ask, “What could my skin be trying to tell me?” Are you repressing emotions? Is there a relationship issue you’re avoiding? Is there some other life circumstance that’s “gotten under your skin”? The body has a wisdom we should listen to.

References

https://drhowardmurad.com/the-brain-in-our-skin-an-interview-with-dr-claudia-aguirre/

http://doctorclaudia.com/about

https://www.janinerod.com/the-hidden-brain-in-your-skin-claudia-aguirre-tedxucla/

No More Menstrual Pain with Light Therapy

No More Menstrual Pain with Light Therapy

Light exposure may affect menstrual cycles and symptoms through the influence of melatonin secretion. In Kaiyan Medical we have been studying portable devices to relieve menstrual pain using low-level light stimulation. Menstrual pain often afflicts women and girls, but the intensity and impact on quality of life vary widely. A cross-sectioned analytical study found that 84 percent reported menstrual pain which often required medication and even resulted in missing work.

Reduce the pain with light therapy

Many women rely on non-steroidal anti-inflammatory drugs, but of course, some prefer to avoid their undesirable side-effects. Other common menstrual pain management methods, according to the National Institutes of Health, include: applying heat with hot water bottles or heating pads, warm baths, or going to the sauna; special diets and dietary supplements; herbal products and herbal teas for medicinal use; homeopathic medicines; and procedures which target pain stimulus such as acupuncture, acupressure or TENS (transcutaneous electrical nerve stimulation). Light therapy devices add another alternative to targeting the pain source with low-level light stimulation applied at acupuncture points.

Light therapy devices improves blood flow and thereby reduces menstrual cramps with via photo-activated modulation of smooth muscle tissue. Usually, the light from the light therapy devices is emitted for a fixed amount of time (from 10 to 20 minutes). The light stimulation reaches the uterus and increases the secretion of nitrous oxide (NO). The NO spreads over the smooth muscle in the uterine cells and under continuous light stimulation produces a phosphate particle called cyclic guanosine monophosphate (cGMP). These particles continuously flow out and relax the smooth muscles so they receive oxygen and nutrition.

In the Archives of Gynecology and Obstetrics, subjects using the low-level light therapy showed statistically significant reduction in pain levels after a month and barely any pain after three months. This compares to a placebo group that showed slight pain reduction over time. The study concluded that

“skin adhesive low-level light therapy on acupuncture points might be an effective, simple, and safe non-pharmacological treatment for dysmenorrhoea.”

In this study, a total of 31 women with dysmenorrhoea were enrolled and randomly assigned to either the active or placebo low-level light therapy groups . Of 31 participants, 21 participants received real light therapy, while the remaining 10 participants received placebo one. All participants in the active low-level light therapy group reported either complete pain relief In the active low-level light therapy group, 16 women had successful results during their menstrual cycle, and 5 women had successful results at the second menstrual cycle.

The most interesting thing about this study, is that they conclude that the direct cause of dysmenorrhoea might not be changes in bioactive substances, such as hormone imbalance, a decrease in serotonin levels or excessive prostaglandin production, but the abnormal function of parts of smooth muscles in the uterus secondary to long-term deficient blood supply into smooth muscle tissue caused by disease or stress. This condition can be improved with light therapy.

Our light therapy products can help as well with back pain, skin, depression, sleep cycles, and pets.


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Tramer MR, Moore RA, Reynolds DJ, McQuay HJ (2000) Quan- titative estimation of rare adverse events which follow a biological progression: a new model applied to chronic NSAID use. Pain 85(1–2):169–182

Smith KC (2010) Laser and LED photobiology. Laser Therapy 19(2):72–78

Tiphlova O, Karu T (1988) Stimulation of Escherichia coli divi- sion by low-intensity monochromatic visible light. Photochem Photobiol 48(4):467–471

Ball KA, Castello PR, Poyton RO (2011) Low intensity light stim- ulates nitrite-dependent nitric oxide synthesis but not oxygen con- sumption by cytochrome c oxidase: implications for phototherapy. J Photochem Photobiol B 102(3):182–191

Witt CM, Reinhold T, Brinkhaus B, Roll S, Jena S, Willich SN (2008) Acupuncture in patients with dysmenorrhea: a randomized study on clinical eVectiveness and cost-eVectiveness in usual care. Am J Obstet Gynecol 198(2):166.e1–166.e8

Schiøtz HA, Jettestad M, Al-Heeti D (2007) Treatment of dysm- enorrhoea with a new TENS device (OVA). J Obstet Gynaecol 27(7):726–728

Jones KR, V ojir CP , Hutt E, Fink R (2007) Determining mild, moderate, and severe pain equivalency across pain-intensity tools in nursing home residents. J Rehabil Res Dev 44(2):305–314

Editorial committee of the Korean Acupuncture and Moxibustion Society (2008) The acupuncture and moxibustion. Zipmundang, Seoul In Korean

Kelly AM (1998) Does the clinically signiWcant diVerence in visu- al analogue scale pain scores vary with gender, age, or cause of pain? Acad Emerg Med 5(11):1086–1090


Why Hollywood Stars Love Light Therapy

Why Hollywood Stars Love Light Therapy

Julia Roberts Uses LED Face Mask | PEOPLE.com
Julia Roberts using LED light therapy mask

From the red carpet to the spotlight stage, Hollywood’s stars are no strangers to the powerful power of light. Their skin is glowing thanks to the latest light-based skin treatment. Stars like Julia Roberts, Kate Hudson, and Jessica Alba have been sharing their experience with LED light therapy masks that are designed to boost collagen, reduce inflammation and banish acne-related bumps and scars.

In Kaiyan Medical we can develop your own beauty light therapy mask worth of the celebrities’ skin.

Kate Hudson using LED light mask
How it Works

These amazing light masks are recommended by dermatologists and estheticians who credit the masks’ multi-colored UV-free wavelengths with improving clients’ complexions.

“Tiny particles of light are called photons, which cells absorb and transform into ATP (adenosine triphosphate), the form of energy that cells use to carry out normal functions,”

says L.A.-based celebrity facialist Shani Darden.

“ATP is then used to power the metabolic process and repair and regenerate cells.”

In short, just like LEDs have been proven to encourage plant growth (what’s a greenhouse without a good grow light?), LEDs can have a similar stimulating effect on skin cells by jump-starting the rejuvenation process.

But not all lights are created equal. Different wavelengths of light have different benefits.

“Blue-light wavelengths destroy bacteria in the skin to improve acne,”

says Toronto-based cosmetic dermatologist Dr. Martie S. Gidon. It’s worth noting that LED therapy is not effective at treating hormonal acne and is only recommended for inflammatory acne — in other words, pimples caused by bacteria — and works best when paired with topical acne medication.

Anti-aging benefits

For anti-aging results, red light therapy is for you.

“Red-light wavelengths penetrate more deeply than blue light and stimulate fibroblasts to produce collagen, resulting in tighter skin and smooth fine lines,”

says Dr. Gidon, who also praises the red light’s anti-inflammatory effect for use post-facials and peels. Another light used in combination with the other two is infrared.

“It accelerates healing and encourages greater product absorption,”

says Shani who recommends clients use a combination of both blue/red light therapy and infrared.

Home LED masks have been growing in popularity, especially with the COVID restrictions. You can opt for flexible home masks for personal use or well, the spa line which packs more lights and cover a bigger zone. With so effective results, it’s no wonder stars like Michelle Williams and Rachel Weisz are opting to lay down inside LED beds in order to treat their entire bodies to the rejuvenating powers of the lights.

If you have question on how to create your own beauty mask, don’t hesitate in contacting us. We will guide you in the whole creative process.

More References


https://ca.hellomagazine.com/health-and-beauty/02017032134254/guiding-light

https://www.womansworld.com/posts/celebrities/julia-roberts-light-therapy-mask

Therapeutic and Aesthetic Uses of Blue & Red Light Therapy Together

Therapeutic and Aesthetic Uses of Blue & Red Light Therapy Together

Acne vulgaris remains one of the most common dermatologic disorders. Clinicians are always searching for new therapies to utilize in their therapeutic armamentarium for this common skin concern. We have many medical therapies at our disposal and these have proven useful in many cases in controlling the disease process. However, some patients need or want other therapies, and laser and light treatments for acne vulgaris have become popular over the past several years.

Regarding LED light therapy for the skin, “There is a science to support it” says Angela Lamb, director of the Westside Mount Sinai Dermatology Practice,

“but it’s important to know its limitations.”

Exposing your skin to different forms of low-level LED light does have anti-bacterial and anti-inflammatory benefits, which is why they’re commonly used for treating redness or acne. Blue light therapy in the right wavelength can be FDA-cleared.

Light Therapy with Aduro Mask

Other blue light trials have supported the efficacy of blue light. Papageorgiou described their experiences with phototherapy comparing a mixed blue and red light system (415 and 660nm) with blue light therapy alone and white light therapy. The results showed that the combination of blue and red light decreased inflammatory acne vulgaris lesions by 76 percent versus 58 percent in the blue light alone group, which were both better than white light (25%). Meffert reported experiences with a high-energy, broad-spectrum, blue light source that combined blue light and UVA with a wavelength of 410 to 420nm and noted marked improvement in patients with pustular acne vulgaris after 10 treatments.

There are a variety of at-home light treatments out there like the Aduro mask (which is patented with medical grade quality) who uses red, orange, purple, infrared, cyan, blue,green and yellow light — but typically what you’ll see on shelves are ones harnessing blue or red light . Blue light is a shorter wavelength that destroys acne-causing bacteria on the skin’s surface, while red light penetrates deeper to help with inflammation, but Hooman Khorasani, the chief of the division of Dermatologic and Cosmetic Surgery at the Icahn School of Medicine at Mount Sinai, says that both blue- and red-light therapy “may reduce the size of the sebaceous glands, so you don’t produce as much oil.”

Blue & Red Light Therapy

The good thing about light therapy is that experts say that there aren’t really downsides if you’re willing to give it a shot. Light treatments have been shown to be relatively safe, with minimal side effects. For acne, Khorasani notes that LED devices won’t take the place of acne fighters like retinoids; instead, they should be used in concert with a multipronged treatment plan — and never for severe acne. If you are combining them with retinoids, Lamb also suggests alternating the days you use either of them, to avoid photosensitivity.

When you combine the blue and red light using the aduro mask, you can get a pink/purple amazing color that will help remove the p-acne causing bacteria from the skin while purifying and cleansing it. Also, you will speed up the healing process and rejuvenate the skin cells increasing the cell regeneration.

More references

https://www.accessdata.fda.gov/cdrh_docs/pdf9/K093963.pdf

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013592

Sigurdsson V, Knulst AC, van Weelden H. Phototherapy of acne vulgaris with visible light. Dermatology. 1997;194:256–260. [PubMed] [Google Scholar]

Taub AF. Photodynamic therapy in dermatology: history and horizons. J Drugs Dermatol. 2004;3:S8–S25. [PubMed] [Google Scholar]

Gold MH, Goldman MP. 5-aminolevulinic acid photodynamic therapy: where we have been and where we are going. Dermatol Surg. 2004;30:1077–1083. discussion 1083-1084. [PubMed] [Google Scholar]

Touma DJ, Gilchrest BA. Topical photodynamic therapy: a new tool in cosmetic dermatology. Semin Cutan Med Surg. 22;2003:124–130. [PubMed] [Google Scholar]

Light Therapy & Vitiligo

Light Therapy & Vitiligo

Our life is full of patches!

Patches in job, career, personal life, and skin too! When we can handle the life patches and hardship with determination, then why not with skin. The skin patches disease is termed as Vitiligo. It is a medical condition where skin loses its color. Vitiligo affect not only physically but also cause a mentally & emotionally. According to VRF, this condition affects 2% of the world’s population. So, around 70 million people across the world have vitiligo. It can affect can affect people of any age, gender, or ethnicity.

How does it occur?

Well many of us are not aware of the biological reasoning behind the condition. It occurs when cells responsible for making skin pigment called melanocytes get destroyed. It can affect any part of your body like limbs, back, neck, face, etc. The body stops producing melanin — the pigment that gives your skin, hair and eyes color.

The symptoms of Vitiligo are like – Patchy, loss of skin color, which usually first appears on the hands, face, and areas around body openings. Other like premature whitening or greying of the hair on the scalp, eyelashes, eyebrows or beard. Vitiligo is an auto-immune disease, where the person’s immune system mistakenly attacks its own body (or host body). Other than that, the skin cells (melanocytes) of the affected person appears to unable to deal with the imbalance of antioxidants and harmful free radicals generated inside the body. This results in cell damage and death.

Light therapy - the hope

Today a number of treatments which are aimed for the restoring the discoloration of the skin. But the best and the convenient is Light Therapy. Especially the narrow-band ultraviolet B (NB-UVB) has come up as one of the safest and most effective therapy for this skin condition.

In this treatment, the depigmented or discolored skin is exposed under a specific wavelength of light for a specific amount of time and using a specified amount of light monitored or prescribed by the dermatologist. The duration of a session can gradually increase as one’s progress based on his/her skin’s response to the light.

Light therapy treatment often involves the usage if specific light which are used in combination with topical medications that are applied to the skin. The topical treatments can be topical steroids, topical calcineurin inhibitors or topical Vitamin D etc. Although the treatment can be used without the topical as well. Topical medications may also be used on their own, without light therapy, however, when the two treatments are used together, the results are typically seen well.

According to the studies, the light therapy session have a great response to treatment. The greatest response is shown majorly on the face and neck. Several retrospective and prospective studies have displayed superior repigmentation, color matching results.

Light therapy is a hope for people who perceive it as an incurable disease. The technology of light therapy helps people to overcome the physical as well as mental aspect of their body.

References:

https://nyulangone.org/conditions/vitiligo/treatments/phototherapy-laser-treatment-for-vitiligo

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536079/

https://www.medscape.com/answers/1068962-87933/how-is-narrowband-uv-b-nb-uvb-used-to-treat-vitiligo

https://www.umassmed.edu/vitiligo/vitiligo-treatment/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607222/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817459/

Healing Muscular Pain with Light Therapy

Healing Muscular Pain with Light Therapy

Light Therapy Healing Muscular Pain

When it comes to pain, we could hardly avert it! Especially the muscle pain. Given that the human body has over 600 muscles, it is tough to avoid muscle pain. Evidently, one out of three Americans is affected by muscle pain annually.

Not only this, Musculoskeletal pain affects around 116 million Americans, which results in poor productivity, missed work or school, fatigue, and lost interest in work.

But doesn’t we treatments for this chronic pain? Of course, we do have several options. Currently, therapies available consist of non-steroidal anti-inflammatory drugs, steroid injections, pain medications, and surgery. Each of these has its own specific risk profiles.

What we need now is an effective solution that is less time-consuming, low risk, safe and non-invasive, and yet cost-effective. All these features are available in treatment; we call Low Laser Light Therapy (LLLT). Light therapy has been in the medical field over the past forty years. Light therapy has been demonstrated to lessen inflammation and edema, promote healing in a range of musculoskeletal pathologies. LLLT is being accepted around the globe. This is an advanced, cost-effective, non-invasive therapy for pain that could elevate the quality of life while reducing your financial strains. The causes of muscular pain are numerous. Hence, LLLT helps people from all fields like sports, fitness, medical, and even old age.


Mechanism of LLLT

In this process, light with a wavelength in the red to the near-infrared region of the spectrum (660nm–905nm) is employed on the skin surface. The reason for using these wavelengths is that they have the ability to penetrate the skin and soft/hard tissues. From various conducted clinical trials, this treatment is proven to have a good effect on pain, inflammation, and repairing of the tissues. The therapy goes from 30 to 120 seconds or more a week, depending upon the pain's severity.

Based on the tissue condition, the therapy can go on for weeks or months. LLLT has resulted in relief and reduction of inflammation, pain relief, and accelerated tissue regeneration.

But how does the light actually work?

LLLT in the Treatment of Pain

Do you know that many acute orthopedic conditions such as strains, sprains, muscular back pain, frozen shoulder, neck and back pain, etc., are amenable to Low Laser Light Therapy (LLLT)?

The Infra-Red light relieves pain in a different section of the body and increases relaxation sensation while also comforting the muscles. LLLT has been shown to enhance the multiplication of cells like fibroblasts, keratinocytes, endothelial cells, and lymphocytes. Fibroblasts and keratinocytes are two major cell types that respond to the inflammatory phase in the repair/regeneration process.

LLLT can enhance neovascularization, promote angiogenesis, and increase collagen synthesis to succor in the healing of acute and chronic wounds. The LED light sessions have shown the ability to heal skin, nerves, tendons, cartilage, and bones. Low-intensity LLLT stimulates mitochondria and also enhances the mitochondrial membrane potential.

The peripheral nerve endings of nociceptors (also known as the pain receptors), consisting of the thinly myelinated and unmyelinated, slow-conducting C fibers, lie within the epidermis. This complex network converts harmful stimuli into action potentials. Moreover, these nerve endings lie on the surface or superficial in nature, making the LLLT wavelength penetration work easy.


Hence, with the rise of chronic pain in different countries, it is imperative to validate cost-effective and safe techniques for managing painful conditions, allowing people to live active and productive lives. Light therapy is constantly evolving in relieving muscular pain. It improves the muscle's endurance, reduces muscle soreness, joint pain, and inflammation.

It’s time to let go of the pain!!

Experience the difference with light therapy from Kaiyan Medical.

More References:

https://pubmed.ncbi.nlm.nih.gov/12605431/

https://pubmed.ncbi.nlm.nih.gov/27472858/

https://arthritis-research.biomedcentral.com/track/pdf/10.1186/s13075-015-0882-0

https://www.sciencedirect.com/science/article/pii/S0004951414601276?via%3Dihub

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743666/

The Key for Better Sex - Red Light Therapy

The Key for Better Sex - Red Light Therapy

The famous fitness coach Ben Greenfield uses red light naked every morning. He flips a switch, flooding the room with a bright red glow. Then he stands naked in the red light for 20 minutes.

“It seems to like, wake you up a little bit; it kind of simulates sunrise,” Greenfield tells. “And it’s almost mildly addictive — the feel-good effect of how you feel after you use one of these.”

Greenfield, a 39-year-old fitness instructor, is an evangelist for red light therapy, a treatment that’s increasingly popular in the world of sports, beauty, and biohacking. Some converts to red-light therapy treatment soak in the ruddy glow for a very personal reason.

Red Light for Testosterone
Red Light Therapy

Light therapy has been for hundreds of years. Recently, we can trace it back to 1967 with Hungarian scientists, red light therapy, scientifically known as photobiomodulation or low-level laser (light) therapy, has made a comeback in the last two decades.

Michael Hamblin, a researcher at Massachusetts General Hospital and professor at Harvard Medical School, explains in a 2017 research paper on the topic that the treatment was confined to a “SCIENTIFIC WASTELAND,” and widely considered “SNAKE OIL.”

But recent studies suggest red-light therapy can improve skin quality, addictions, pets’ mood, sleep quality, depression, muscle recovery, and relieve pain.

Indeed, some studies suggest light therapy stimulates mitochondria, a.k.a. the “powerhouse” of a cell, and increases the production of adenosine triphosphate, the organic chemical that carries energy in the body and plays a big role in metabolism.

Bio-hacking Yourself

In Kaiyan Medical, we are on a constant quest to optimize our brains and bodies. Some studies have actually demonstrated that exposing the torso or the testes to light can potentially increase testosterone. In fact, studies on the effects of light on the testes go way back to 1939, when researchers exposed various parts of men’s bodies to UV light. They found that men’s testosterone levels went up by 120% when the participants’ chests were exposed to UV light, and they went up by 200% with UV exposure to the genital area.

Sunlight exposure directly to the testes reportedly has an even more profound effect, boosting production in Leydig cells (the cells that produce testosterone) by an average of 200%

The theory is this: while sunlight has many beneficial effects, such as vitamin D production and improved mood, it is not without its downsides. Too much exposure to sunlight, particularly to sensitive areas like the skin around your precious ball sac, can create sunburn, excess radiation, inflammation and damage. And let’s face it: you don’t want a shrunken, shriveled, dehydrated dick, no matter how impressive the tan.

Red light, however, is different than sunlight. Red light is comprised of light wavelengths in the range of 600–950 nanometers (nm). According to red light therapy proponents, red light works to stimulate ATP production, increase energy available to the cell and in particular, increase the activity of the Leydig cells in your testes, which are the cells responsible for testosterone production.

Optimizing Sex

In the last five years, light therapy researchers and red-light therapy companies set their sights on men like Greenfield — the guy who gets naked every morning in his home office.  “The impact of [low-light therapy] on sexual health is an emerging field, but I see its potential to improve sexual function and libido with recent studies,” Hamblin says. “It has been shown to improve sperm function and may have applications in increasing fertility in both men and women.”  Research on sexual health applications of red-light therapy is relatively minimal in men, and basically nonexistent for women. A few studies in animals suggest red light therapy might influence LEYDIG CELLS — the body’s sperm producers, which live in the testicles. Another study in humans suggests red light therapy can increase testosterone levels and sexual satisfaction.

Don't let the Fear Defeat You

Sexual health issues — from “low T” to erectile dysfunction — can be challenging to treat because of the social stigma, Goldstein explains. There’s a “fear,” the urologist says. Many men are ashamed and avoid seeing a doctor.  “If they can get something over the counter that's purported to help them, millions of men will be willing to try it and maybe they would never buy it again,” Goldstein tells.  “Good advertising and good marketing will create a market for a product, whether it's proven to be of value or not.”  

Reduce Infertility

One of the biggest concerns for those who suffer from Low-T is infertility. Several studies show that red light therapy helps increase sperm motility, which is essential for successful impregnation. In 2017, researchers from the University of California, San Diego, found that sperm exposed to 630nm red light increased sperm swimming speed and force.

A similar study by researchers from Iran found an after exposing sperm to an 830nm NIR light device. Sperm motility is associated with cellular energy; more energized sperm will swim with greater vigor. This is a vital component of male reproductive health, and success in improving sperm motility points to the use of red light therapy as a way to treat male infertility.

Red Light for Testosterone
Feeling Like a Super Hero

On top of using red light, both Greenfield and Wiles eat healthy, work out regularly, and practice stress-management techniques. Which habit, or a combination of each, helps them “optimize” their sex life or their physical health isn’t clear.

Even though the research doesn’t match their claims — yet— Greenfield and Wiles have no intention of slowing down.  “Before I go and give a presentation or if I'm giving a lecture or even if I'm just seeing a patient in clinic, I'll go ahead and throw that thing on and I will feel like a million bucks," Wiles says. "I’ve noticed increased overall sexual health, sexual satisfaction, and stamina."  Recently, Greenfield has been shining the light for one very specific reason: He and his wife are trying for a baby.  “Sometimes if I know I've got like a date night with my wife or we're going to have sex that night, I'll wait until the evening to do the treatment because the immediate effects are even better, especially the blood flow," Greenfield says.  "Erectile quality is just better right after you use it.”

More References

https://platinumtherapylights.com/blogs/news/red-light-therapy-for-boosting-testosterone

https://www.inverse.com/mind-body/red-light-therapy#:~:text=A%20few%20studies%20in%20animals,testosterone%20levels%20and%20sexual%20satisfaction.

Light Therapy - Color Meaning

Light Therapy - Color Meaning

Introduction to Color Light Therapy

Color Light therapy is based on the idea of restoring balance by applying color to the body. Its history is rooted as far back as the Mayan culture.

In India, Ayurveda, an ancient form of medicine practiced for thousands of years, is based on the idea that every individual contains five elements of the universe that are present in specific proportions unique to each individual, including their personality type and constitution. When these elements are out of balance, Ayurveda works with the energies inherent in the colors of the spectrum to restore this balance.

In ancient Egypt the art of healing with color was founded in the Hermetic tradition, the Ancient Egyptians and Greeks used colored minerals, stones, crystals, salves, and dyes as remedies, and painted treatment sanctuaries in various shades of color.

In China, traditional Chinese medicine incorporates color to be associated with each organ and elemental system. This healing method looks at the idea that every individual is a balance. The first color wheel was invented by Sir Isaac Newton. He split white sunlight into red, orange, yellow, green, cyan, and blue. He then joined the two ends of the color spectrum together to show the natural progression of colors.

Light Therapy has been valued throughout history as a remarkable source of healing. Today, the therapeutic applications of light and color are being investigated in major hospitals and research centers worldwide. Results indicate that full-spectrum, ultraviolet, colored, and laser light can have therapeutic value for a range of conditions from chronic pain and depression to immune disorders.

Wellness Benefits

Light Therapy has been reported, as part of a healthy lifestyle, to temporarily reduce swelling, relieve pain, decrease inflammation, accelerate open wound healing and greatly reduce overall recovery after medical/surgical procedures. Patients have demonstrated an increased range of motion, decreased muscle tension and spasm, and improved circulation.

Rejuvenating LED light therapy can be used for temporary pain management such as joint and back pain, sore or torn muscles, sprains, arthritis, post-surgical scars, burns, wounds, and more. When used with infrared technology, light therapy (phototherapy) is one of the most effective and non-invasive ways to improve overall wellness.

Light therapy is also used to temporarily relieve Seasonal Affective Disorder (SAD). SAD affects individuals when the lack of sunlight results in seasonal depression. Phototherapy helps with SAD by resetting the internal biological clock (Circadian rhythms), helping individuals sleep better, and regulate their mood. Even companies, such as GE and Philips, have created phototherapeutic products to improve and regulate mood.

Cosmetic Benefits

Light therapy is also a growing treatment for anti-aging. Many individuals have seen a temporary reduction in the appearance of fine lines, wrinkles, crow’s feet, and age spots.

Light therapy is “effective at improving the appearance of the face, neck, and chest by reducing the signs of aging, wrinkles and age spots”, says Web M.D. Combined with infrared therapy, LED phototherapy can be a great way to revitalize skin.

Healing With Color

Color is light split into different wavelengths vibrating at different speeds and at different frequencies. Objects that ABSORB all wavelengths and DO NOT reflect are black in nature. Objects that REFLECT all wavelengths and DO reflect are white in nature. Between black and white lies COLOR. Colors are wavelengths of energy that, to us, appear as color because of the potential and capabilities of the object to either absorb or reflect the energy.

Red Light

In the early 1990s, RLT was used by scientists to help grow plants in space. The scientists found that the intense light from red light-emitting diodes (LEDs) helped promote the growth and photosynthesis of plant cells.

The red light was then studied for its potential application in medicine, more specifically to find out if RLT could increase energy inside human cells. The researchers hoped that RLT could be an effective way to treat the muscle atrophy, slow wound healing, and bone density issues caused by weightlessness during space travel.

You may have heard of red light therapy (RLT) by its other names, which include:

  • photobiomodulation (PBM)
  • low-level light therapy (LLLT)
  • soft laser therapy
  • cold laser therapy
  • biostimulation
  • photonic stimulation
  • low-power laser therapy (LPLT)

Red is called “The Great Healer”. So far is the most popular light therapy. To wind down before bed, use red light. “The color signals that it’s night, which may encourage the body to produce melatonin,” says Michael Breus, Ph.D., an advisory board member for SleepScore Labs.

Red light can also improve your workout. Just one to five minutes of exposure to red and infrared light right before exercise boosted strength and prevented soreness, says Ernesto Leal-Junior, Ph.D., the head of the Laboratory of Phototherapy in Sports and Exercise at Nove de Julho University in Brazil. “Certain wavelengths of red and infrared light-660 to 905 nanometers-reach skeletal muscle tissue, stimulating the mitochondria to produce more ATP, a substance that cells use as fuel,” he says.

Green Light

Green is the universal healing color. Originally, the color of love. Green is midway in the color spectrum; therefore, it contains both a physical nature and a spiritual nature, in equal balance and in equal harmony.

Gazing at green light can reduce chronic pain (caused by fibromyalgia or migraines, for example) by up to 60 percent, according to a study in the journal Pain, and animal studies have shown that the beneficial effects can last up to nine days. “Looking at green light seems to lead to an increase in the body’s production of enkephalins, pain-killing opioid-like chemicals. And it reduces inflammation, which plays a role in many chronic pain conditions,” says researcher Mohab Ibrahim, M.D., Ph.D.

More studies are needed before doctors can make recommendations on how and how often to use green light to treat migraines and other pain, and Dr. Ibrahim says you should see a physician before trying to treat yourself at home. But at this point research indicates that exposing yourself to an hour or two every night-either by using a green light bulb in a lamp or by wearing glasses fitted with tinted optical filters-may decrease migraines and other types of chronic pain

Helps to treat and prevent hyper-pigmentation by inhibiting the production of excess melanin which then prevents it from traveling to the surface. It will help break up the melanin clusters that are already on the surface.

Yellow Light

Yellow helps awaken mental inspiration arousing a higher mentality. Thus, it is an excellent color for nervous or nerve-related conditions or ailments; fueling the solar plexus. Yellow has a very enriching effect upon the intellect. Yellow can be used for conditions of the stomach, liver, and intestines. It can help the pores of the skin by repairing scarred tissue. These rays have an alkalizing effect which strengthens the nerves. Awakening, inspiring, and vitally stimulating the higher mind promoting self-control. Typical diseases treated by yellow are constipation, gas, liver troubles, diabetes, eczema, and nervous exhaustion. Providing clarity of thought, increasing awareness, stimulating interest, and curiosity yellow energy is related to the ability to perceive or understand.

The yellow is used for treating redness, flushing, irritation, and Rosacea. It may also reduce the appearance of the tiny blood vessels on the nose and face.

Blue Light

Blue light therapy technology is an additional option for the treatment of acne. Research has shown in-office and at-home systems produce positive results.

“Blue light therapy effectively helps alleviate this common skin condition affecting 50 million Americans and 94 percent of all females, according to Judith Hellman, MD, a board-certified dermatologist, in practice in New York City. Dr. Hellman, who practices medical dermatology and specializes in dermatological surgery, laser surgery, and anti-aging skin treatments, explains how the blue light treatment system works for acne, its uses, and her clinical experience with the technology.

Cyan Light

It is used as a gentle acne treatment to control oil production in the skin as well as reduce inflammation. It also promotes the synthesis of protein and collagen.

Orange Light

Orange has a freeing action upon the mind, relieving repression. Because orange is a blend of red and yellow, it combines physical energy with mental wisdom, inducing a transformation between lower physical reaction and higher mental response. Thus, it is often referred to as “The Wisdom Ray.” Orange is warm, cheering, and non-constricting.

Through orange, we are able to heal the physical body (red) and, at the same time, induce within the mind (yellow) greater understanding. Orange helps assimilate new ideas. Orange is the best emotional stimulant, helping to remove inhibitions paving independent social behavior. Bring joy to your workday and strengthen your appetite for life. Orange aids in repairing inflammation of the kidneys, gallstones, menstrual cramps, epilepsy, wet cough, and all sinus conditions.

Purple Light

Violet is the last color we can see before light passes on to ultra-violet. Violet purifies our thoughts and feelings giving us inspiration in all undertakings. The violet energy connects us to our spiritual self bringing guidance, wisdom, and inner strength and enhances artistic talent and creativity. Leonardo da Vinci proclaimed that you can increase the power of meditation ten-fold by meditating under the gentle rays of Violet, as found in church windows.

Light therapy uses colors for their proposed wellness abilities in treating emotional and physical disturbances. Light therapy is based on the premise that different colors evoke different responses in people. For example, some colors are considered to be stimulating, whereas others may be soothing. Color therapy has been suggested for many uses, based on tradition or on scientific theories. Consult with a health care provider before using color therapy for any use.

Infrared Light

Infrared light penetrates to the inner layers of the skin at about 2 to 7 centimeters deep. Hence, it reaches the muscles, nerves, and even the bones. Many studies have shown that a frequency of infrared light, with wavelengths from 700 to 1,000 nanometers, is best used for healing inflammatory conditions.

The use of electricity for healing purposes began in 2,750 BC when people used electric eels to give electric shocks. Electricity and magnetism were used in people with just little success. However, in 1975, transcutaneous electrical stimulation (TENS) was developed to treat chronic pain. It was not until recently that infrared therapy was developed to improve wound healing, reduce the pain caused by arthritis, boost endorphin levels, and bioactivate neuromodulators.

Infrared therapy technology allows people to harness the benefits of the sun, without being exposed to harmful ultraviolet rays. Also, infrared therapy is safe and effective, without adverse side effects. As a matter of fact, infrared light is safe and is used even for infants in neonatal intensive care.

Infrared light is absorbed by the photoreceptors in cells. Once absorbed, the light energy kickstarts a series of metabolic events, triggering several natural processes of the body on a cellular level.

Kaiyan Medical

In Kaiyan, we are in love with light therapy. We believe in the natural balance in our bodies. We develop devices such as the Aduro mask which will provide you with the full range of color light therapies.

References

https://www.estyspot.com/blogs/esthetician-tips/an-estheticians-view-of-led-therapy-benefits-for-all-7-colors

https://www.the-dermatologist.com/content/acne-treatment-blue-light-therapy-benefits-0#:~:text=A%3A%20Blue%20light%20kills%20the,oil%20glands%20in%20the%20skin.

https://www.healthline.com/health/red-light-therapy#summary

https://www.estyspot.com/blogs/esthetician-tips/an-estheticians-view-of-led-therapy-benefits-for-all-7-colors

Deppe A. Ocular light therapy: a case study. Aust J Holist Nurs 2000;7(1):41.

Geldschlager S. Osteopathic versus orthopedic treatments for chronic epicondylopathia humeri radialis: a randomized controlled trial. Forsch Komplementarmed Klass Naturheilkd 2004;Apr, 11(2):93-97.

Maher CG. Effective physical treatment of chronic low back pain. Orthop Clin North Am 2004;Jan, 35(1):57-64.

Natural Standard Research Collaboration, Chief Editors: Ulbricht C, Basch E, Natural Standard Herb and Supplement Reference: Evidence-Based Clinical Reviews, USA. Elsevier/Mosby, 2005.

Ohara M, Kawashima Y, Kitajima s, et al. Inhibition Of lung metastasis of B16 melanoma cells exposed to blue light in mice. Int J Molecular Medicine 2002;10(6):701-705.

Wileman SM, Eagles JM, Andrew JE, et al. Light therapy for seasonal affective disorder in primary care: randomised controlled trial. Br J Psych 2001;178:311-316.

Wohlfarth H, Schultz A. The effect of colour psychodynamic environment modification on sound levels in elementary schools. Int J Biosocial Res 2002;(5):12-19.

Zifkin BG, Inoue Y. Visual reflex seizures induced by complex stimuli. Epilepsia 2004;45(Suppl 1):27-29.

Fighting Breast Cancer with Light Therapy

Fighting Breast Cancer with Light Therapy

Researcher fighting breast cancer with light therapy
"Metastatic breast cancer can be a devastating diagnosis with high rates of relapse and death, and there are currently no effective therapies,"

Nalinikanth Kotagiri, MD, Ph.D. says.

"Despite newer treatments, many patients still succumb to the disease. Major limitations include acquired resistance to therapies and serious side effects from treatment. Due to the widespread location of breast cancer cells, particularly in the bone marrow, which harbors the tumor cells as well as vital stem cells, the risk of toxicity is even higher with conventional therapies. Therefore, new therapeutic strategies that selectively destroy tumor cells, increase treatment efficacy, prevent relapse and reduce side effects by sparing the healthy stem cells are necessary."


This is why Nalinikanth Kotagiri, MD, Ph.D., assistant professor in the James L. Winkle College of Pharmacy and a cluster hire for the Cincinnati Cancer Center, is hoping to study ways ultraviolet light can activate light-sensitive drugs to treat this invasive breast cancer and provide that light at the end of the tunnel patients yearn for.

Kotagiri has been awarded the Department of Defense Breast Cancer Breakthrough Award—over $600,000 for three years—to try to do just that. His project will focus on light-mediated therapies, which could activate light-sensitive drugs to target only the cancerous cells.

"Therapies such as photodynamic therapy (PDT), involving light and a photosensitizing chemical substance, which used in conjunction with molecular oxygen can cause cell death, offer a high degree of control that is effectively used to manage cancer in early to advanced stages," he says. "It operates on a simple principle where a light-sensitive drug, which is otherwise nontoxic, introduced into certain tissues can cause cell death when activated by light. Despite the promise of PDT, it can't penetrate tissue deeply so its use is limited. Also, current light-sensitive drugs require oxygen to be effective, but many tumors, including breast tumors, have pockets of low oxygen or grow in regions where oxygen is either low or absent, which could prevent effective application of PDT in cancer treatment."

However, Kotagiri says recent work in the lab has led his team to a "two-pronged approach" in addressing these issues.

"We've been using ultraviolet (UV) light from radionuclides (radioactive nuclide or atom), which are already used to image tumors and tissues, and tried to solve oxygen dependence by using metal-based light-sensitive drugs for depth- and oxygen-independent PDT," he says. "By replacing the external light source, such as lasers and lamps, with light from radionuclides as an 'internal' light source, we've been able to better control therapy in the body.
"This could mean more effective therapies with minimal toxicity to vital organs and tissues. Since radionuclides are used in imaging and locating tumors, we can now simultaneously image and treat breast cancer metastasis using the same radionuclide."

Using animal models, researchers in Kotagiri's lab will test whether radionuclide light activation of tumor targeting, light-sensitive drugs will destroy metastatic cancer cells—including those that are resistant to traditional therapies.

"Since how we're killing the cells is not dependent on a certain molecular pathway, the technology could be applicable to treat a wide variety of breast cancers," he adds. "This has the potential to be a common image-guided treatment strategy to treat patients in early as well as advanced stages of the disease, and because of the safety of this treatment strategy, it could be effectively used alongside other treatments, like chemotherapy and immunotherapy, without the risk of additional side effects.
"This could tremendously benefit patients, as it could potentially improve therapeutic outcomes in addition to setting a precedent to tailor other FDA-approved light-sensitive drugs as radionuclide activated therapies, expanding the scope and range of the diseases these drugs currently treat. If proven beneficial, this treatment could be ready for a patient population in 5 to 10 years, since all the materials involved have already been used in humans—this could be an exciting breakthrough."
Clinical Trial - The Effects of Light Therapy to Treat Cancer-related Side Effects

ClinicalTrials.gov Identifier: NCT04418856

Besides what Kotagiri said, severe fatigue, depression, sleep problems and cognitive impairment are the most commonly reported side effects of cancer treatment. These aversive side effects are hypothesized to be related to the disruption of circadian rhythms associated with cancer and its treatment. Exposure to Bright White Light (BWL) has been found to synchronize the circadian activity rhythms but research with cancer patients has been scarce. Therefore, the proposed randomized control trial (RCT) will test if systematic light exposure (sLE) will minimize overall levels of cancer-related fatigue (CRF), depression, sleep problems and cognitive impairment among breast cancer patients undergoing breast cancer treatment (i.e., surgery, chemotherapy). SLE incorporates the delivery of harmless UV-protected BWL or Dim White Light (DWL - standard comparison in light studies) delivered to patients by using special glasses for 30 minutes each morning, during their treatment.

Learn more about the how to improve your circadian rhythm and light therapy & breast feeding

References

https://medicalxpress.com/news/2018-10-breast-cancer-therapy.html

https://www.mayoclinic.org/tests-procedures/photodynamic-therapy/about/pac-20385027#:~:text=Photodynamic%20therapy%20(PDT)%20is%20a,energy%2C%20usually%20from%20a%20laser.

https://clinicaltrials.gov/ct2/show/NCT04418856

5 Biohacking Techniques

5 Biohacking Techniques

What is Biohacking?

Biohacking is the practice of changing our chemistry and our physiology through science and self-experimentation to energize and enhance the body. It’s a broad definition, but that’s also because the concept is constantly evolving. It includes implementing lifestyle and dietary changes that improve the functioning of your body, as well as wearable technology to help you monitor and regulate physiological data. It can even run to extremes such as using implant technology and genetic engineering.

The possibilities are endless, but they are all rooted in the idea that we can change our bodies and our brains, and that by doing so we can ultimately become smarter, faster, and better as human beings.

Start biohacking your body by using wearables like the FitBit or the Apple Watch to track the way you operate. You could also start experimenting with the power of music in your everyday life and adopting a sustainable healthy diet. But if you’re ready for something new, and something different, consider one of these non-invasive methods from our biohacking guide:

Biohack Tip 1: Red Light Therapy

Have you ever spent a lot of time indoors and begun to feel… off? Our bodies and brains need light to function at their best. Not only does the sun give us an important dose of vitamin D, but it helps us in a number of other physiological and emotional ways. Let’s look a little closer – specifically at the light wavelengths between 600 and 900 nanometers (nm). How does this range of light waves impact us and how can we use it to biohack the body?

Studies have shown that your body responds particularly well to red and near-infrared wavelengths, which range from 600 to 900 nm. This particular range of light waves is absorbed by the skin to a depth of about 8 to 10 millimeters, at which point your mitochondrial chromophores absorb the photons. This activates a number of the nervous system and metabolic processes.

In plainer terms, red light therapy has become an increasingly popular form of biohacking used to treat a number of conditions. It has been proven to relieve pain, reduce inflammation, and restore mood. And because it is a non-invasive and non-chemical treatment, it’s not as intimidating as other forms of biohacking.

Biohacking Tip 2: Functional Music

With over 100 billion neurons that are constantly using electricity to talk to each other, your brain is like Grand Central Station. If everyone is chattering loudly at the same time, it can be tough to concentrate on what you need to get done. That’s where music biohacking comes in. Brain activity can be measured in a wave-like pattern and determines if you feel alert, sleepy, relaxed, or stressed. Things that can affect your brainwaves include the activity you are currently performing, how much restorative rest you’ve had, and what you’ve just eaten or drank.

One of the most reliable ways to change your brainwaves is through a consistent sound wave. Audio entrainment, a form of music biohacking, uses binaural beats and tones to synchronize with your brain waves and induce a meditative, relaxed state. You can access programs developed specifically for your own brain and the activities you want to accomplish at Brain.fm. If you’re not ready to go that far, you can still change your mood and mindset by queuing up your favorite playlist and listening while you work out, cook breakfast, or commute to work.

Biohacking Tip 3: Osteostrong

We talk a lot about cardiac health. After all, heart disease is the #1 killer of women in the United States. Everyone needs to be aware of cardiovascular diseases and how to protect themselves as best they can. As a culture, we also talk a lot about skin health – slathering on sunscreen as part of our daily routine and supplementing our diets with collagen-boosting foods. Weight loss, inflammation, memory, GI health, and how an unhealthy diet and lack of exercise can prematurely age you – these are all at the forefront of our minds. But how often do we think about the health of our bones?

A decrease in bone health creeps up on you and most people are unaware of how bone density changes over time. Roughly up until the age of 30, men and women actually build more bone than they lose, so we are constantly strengthening our bones and working on bone density. But when we hit our mid-30s, things change. And if you’ve passed that benchmark, you may have felt that shift.

After reaching their mid-30s, women lose about 2% of bone density every year, and that continues for a few years following menopause. This leaves women with a high likelihood of experiencing osteoporosis.

So what do you do? Consider trying OsteoStrong, a non-pharmaceutical way of improving bone density, strength, and balance as one of your biohacking techniques.

According to OsteoStrong’s website, research indicates that the stimulus required to activate the growth of healthy bone tissue is 4.2 multiples of body weight. However, this level of force would be exceptionally difficult to achieve on your own. That’s why OsteoStrong utilizes the Spectrum System, which is part of a new category of devices called the Robotic Musculoskeletal Development System (RDMS).

Biohacking Tip 4: Gratitude

How we view life has a huge effect on our moods, how we treat others, and our general levels of fulfillment. When you have an abundance mindset, you’re consistently grateful for everything that comes your way and is always focused on the positive. Have a hard time adopting this type of perspective? Changing your mindset is really about nothing more than practice. You need to consistently refocus your brain to see the positive in every situation until it becomes second nature. These biohacking techniques and tools can help:

  • A gratitude journal in which you write three to five things you’re grateful for helps you reframe the day to focus on the positive and reflect on all the good things that happen to you.
  • Take a gratitude walk where you give thanks and send positive energy to every living thing you see. If you walk to work or take a morning jog, you can easily incorporate this into your normal routine.
  • Write a weekly letter of gratitude to someone who has helped you or who means a lot to you. It could be a family member, a long-lost friend, or even a coworker who always remembers to stock your favorite coffee.
  • Begin the day with a ritual, such as meditating, and set an intention to be grateful for all you encounter.
Biohacking Tip 5: Supplements

Exercising, eating right, and developing the right mindset are important steps to unlocking an extraordinary life. Biohacking helps you take this to the next level by incorporating supplements that improve focus, increase energy, and help your body benefit from the most bioavailable forms of nutrients available.

We often don’t get all the vitamins and minerals we need to keep us at peak performance. High-quality supplements in the form of pills, shakes, bars, or drinks can fill the nutritional gap and help boost performance, detoxify our systems, and achieve daily energy.

Tony has created a variety of health supplements, drinks, and bars that help you feel your best every day and make biohacking the body easy.

Red Light Therapy - 101

Red Light Therapy - 101

We are not just made of biochemical matter. We are charged energy beings, constantly interacting with the environment. Light plays a crucial role in this natural process. Comprehensive new research has unearthed a full new understanding of how our cells function optimally. Food is not the only way we obtain energy; the light also charges us.

Science now shows your body operates like a battery. Certain wavelengths of sunlight power it, and your general health is determined by your ability to receive and maintain a charge. This is what light therapy is about.

What is Red Light Therapy

Light at certain wavelengths is scientifically proven to interact with the body in beneficial ways.

Red light, comprising both red and near-infrared wavelengths, is a unique healing part of the electromagnetic spectrum, and it is one of the most natural ways to charge the body. It is now used as a new form of therapy under the umbrella term Photobiomodulation(PBM)

Red light wavelengths ranging from 600–680nm. Red light boosts the formation of collagen and elastin and assists in cell communication. It penetrates superficially and can be used for skin conditions.

Near-Infrared wavelengths ranging from 750–850nm. NIR stimulates healing, increases mitochondrial function, and improves blood flow and tissue oxygenation. It penetrates deeper into the body.

A high-quality home device like those produced by Kaiyan uses medical-grade LEDs to shine natural red and near-infrared light on your body. Like the wavelengths of light your body needs from natural sunlight, without the heat or UV rays that cause sun damage and without the need for sunny weather. Check the list of best light therapy masks.

How to Recharge your Body

Electric charge is a fundamental property of the body. The surfaces in our bodies — such as membranes, proteins, and DNA — are all charged, negatively or positively, depending on whether they lose or gain electrons.

At the core of your body’s power to heal itself are sub-cellar organelles called mitochondria. The number of mitochondria in a cell varies widely by organism, tissue, and cell type and are concentrated in organs with high energy demands such as the brain, heart, liver, skin, and muscles.

This is because mitochondria generate most of the body's chemical energy supply via the ATP (adenosine triphosphate). They also regulate various other tasks, such as signaling, cellular differentiation, and maintaining control of the cell cycle and cell growth. This is why they are often referred to as the powerhouse of the cell.

Mitochondria
  1. LED light at a wavelength from 600–680nm(red) and between 810–850nm(infrared) is delivered to the tissue via the red light therapy device.
  2. The light enters the cell’s mitochondria and is absorbed by the chromophores, including the protein cytochrome c oxidase(CCO) and EZ water, increasing its activity.
  3. As a result of this highlighted activity, three molecules are affected. Adenosine Triphosphate(ATP), Reactive Oxygen Species (ROS), and Nitric Oxide (NO).
Water

Approximately 70% of our body weight and 99% of our bodies ’ molecules are made of water, and this water is in a charged state.

Recent research by Prof Gerald Pollock of the University of Washington has shown that water adjacent to a cell or mitochondrial membrane is so-called structured water. This is also called EZ (exclusion zone) water because it creates a separation of charge. Positive proton is excluded and pushed to the bulk water, and a lattice-like negatively charged water for near the membrane. This increases the voltage across the membrane—this charge separation of water in the body functions as the positive and negative poles of a battery.

What Does “Red Light Therapy” Mean?

As a term, “red light therapy” refers to treatments from LEDs or cold lasers that deliver wavelengths of natural red and near-infrared light.

The term does not include white light, blue light, or blue LED masks, and it is not the same as full-spectrum light. Some people may include infrared or far-infrared wavelengths along with red light therapy, but those are typically used in dry saunas because of their ability to produce heat. Red light therapy does not rely on heat, a major difference between natural light treatments and heat-based modalities like an infrared sauna, traditional sauna, or other heat therapy type.

Generally, “red light therapy” describes natural light treatments that deliver the same therapeutic red and near-infrared wavelengths as natural sunlight. This differs from artificial light treatments like tanning — or bright light therapy from light therapy lamps, lightboxes, or happy-light if you’re interested in natural light treatments for seasonal affective disorder.

The following terms may also call red light therapy: RLT, photobiomodulation (PBM), phototherapy, LED therapy, LED light therapy, infrared therapy, low-level laser therapy, or low-level light therapy (LLLT).

A Multilevel Treatment

Red light therapy works on multiple levels in the body.

Molecular

  • Chromophores, cytochrome c oxidase, water, opsins
  • Retrograde mitochondrial signaling
  • Light-sensitive ion channels
  • Adenosine triphosphate ATP
  • Reactive Oxygen Species ROS

Calcium

  • Heat-shock proteins
  • Melatonin
  • Brain-derived neurotrophic factor
  • Gene transcription factors
  • Akt/mTOR/CyclinD1 pathway

Cellular

  • Inflammation, Cytoprotection, Proliferation
  • Protein synthesis
  • Stem cell production and migration
  • Immune cell viability
  • Retrograde mitochondrial signaling
  • Transforming growth factor
  • Pro-and anti-inflammatory cytokines
  • Vascular endothelial
  • Mitochondrial membrane potential

Tissue

  • Muscles: Increase endurance, tone density
  • Brain: Improves cognition and immune
  • Nerves: Repair and pain relief
  • Healing: Bones, tendons, and wounds
  • Hair: Increases growth
  • Skin: Improvements of the collagen network, anti-aging, skin disorders
  • Fat: Fat re-absorption improved by enhanced micro-circulation
  • Lymph: Improved immunity
Systemic Effects

Red light therapy affects multiple bodily systems:

Fascia

The fascia is a complex web of sensitive and highly interconnected connective tissue beneath the skin that attaches, stabilizes, encloses, and separates muscles and other internal organs.

Fascia is primarily made from hydrated collagen-Protein chains in a triple helix formation surrounded by water, with a capacity to generate an electric charge in response to applied mechanical stress (piezoelectric).

The bio-electrical nature of the collagen-rich matrix is the key to understanding how pathological changes in one part of the body may cause a cascade of “remote effects” in seemingly unrelated areas and organ systems. The fascia is the long-overlooked but absolutely crucial interconnecting organ of the human body. The therapeutic effect of red light energy can be carried through the fascia network to other parts of the body where it is needed. This is turn, elevates the body’s capacity to communicate via this charged matrix in a positive feedback loop.

The well-known energy meridians of traditional Chinese medicine may actually be low resistance pathways operating through the fascia, conveying energy to the rest of the body.

Gut-Brain Axis

The gut-brain axis links the emotional and cognitive center of the brain with peripheral intestinal functions. Red light energy applied to the abdomen area can therefore influence mood and neuropsychological issues via several mechanisms:

  • Reduction in bowel inflammation and gut spasms.
  • Stimulation of neurotransmitters and hormones in the gut, including serotonin, leptin, and ghrelin.
  • Modulation of the micro-biome. The gut microbes are sensitive to light energy and respond to light energy with differences in growth, migration, and proliferation of the different species.
  • The increasing availability of neurotransmitters activates the brain’s immune system, increases blood flow, and removes toxins.
  • Increased blood circulation and reduced blood pressure leading to a reduction of anxiety and brain fog.
  • Modulation of the vagus nerve, one of the biggest nerves connecting the gut and brain. This plays an important role in stress and social communication, communicating motor and sensory impulses to every organ in the body.

Immune System

Beaming red light and near-infrared light onto cells creates a short, low-dose metabolic stress that builds up the cells' anti-inflammatory, anti-oxidant, and natural defense systems, making the body stronger and more resilient to infections.

This is the concept of hormesis; safe, low-level exposure to stressor results in increased resistance to illness. Red light has been shown to influence the immune response in several ways:

  • Activation of the mast cells leading to the movement of leukocytes and reduced inflammation.
  • Mast cell DE-granulation and the release of pro-inflammatory cytokines.
  • Increased infiltration of the tissues by leukocytes.
  • Enhanced proliferation, maturation, and motility of fibroblasts
  • Increased production of fibroblast growth factor.
  • Lymphocyte activation and proliferation.
  • Macro-phages activated to act as phagocytes.

Circulatory System

Red light therapy has been shown to aid the circulatory system's functioning and increase the micro-circulation of blood, one of the most recognized and well-documented effects of this therapy.

Red light stimulates the formation of new capillaries carrying more oxygen to the body.

A good oxygen supply is intricately involved in numerous biological processes, including cell proliferation, angiogenesis, and protein synthesis, required to restore tissue function and integrity.

Increased circulation allows for waste products to be carried away more effectively. It triggers and heightens the body’s own scavenging process for and ingesting degenerated cells for clean-up.

In fact, increased micro-circulation of blood is thought to be the most vital function for healing the body for almost every illness. For general well-being, Nutrient-rich blood and efficient waste removal is strongly linked to good health.

Nervous System

The nervous system is a complex electrical system, including the brain and spinal cord. It collects, processes, and responds to the input of energy-be it light, sound, heat, or pressure — and it relays these messages to the brain and around the body.

Red light energy affects the nervous system in several crucial ways:

  • Myelination of fibers and a better lamellar organization of the myelin sheath.
  • Improvement of electrophysiological function.
  • Facilitation of neural regeneration.
  • Release of growth factors.
  • Increase of vascular network and collagen.
  • Faster regeneration of nerve lesions and functional improvement of damaged nerves.

The peripheral nerves can be damaged by infection or high sugar levels in the case of diabetic neuropathy.

Red light therapy is being explored as a promising drug-free therapy for all kinds of nerve damage.

Stem Cells

At the frontier of science, red light therapy shows huge promise in current research to stimulate the growth of stem cells in the body and maximize the effect of stem cell implantation for a wide variety of medical purposes.

Therefore, red light may be useful after surgery to stimulate stem cells to aid the repair of tissues and possibly organs.

Light at certain wavelengths has also been shown to coax stem cells to repair teeth, so red light therapy could soon revolutionize dental treatments. Indeed, some progressive dental clinics now offer red light therapy as an alternative to conventional drug and drill treatments.

Red light therapy has been shown to stimulate mesenchymal stem cells in the bone marrow to enhance their capacity to infiltrate the brain.

This has implications for healing degenerative conditions such as dementia, Alzheimer’s, and Parkinson’s disease , currently lacking any orthodox treatment solution.

Where Did Red Light Therapy Come From?

Red light therapy has become a popular natural health intervention, both in professional settings and with home devices.

Light therapy technology has been used in medicine for decades, and NASA experimented with red light therapy use in space in the 1980s and 1990s. In the last 10–20 years, red light therapy has become more widely used thanks to breakthroughs in LED lighting technology that have made affordable home devices possible.

Major advances in clinical light therapy research, and increased public interest in natural health technologies, have also contributed to the growing use and popularity of red light therapy.

In 2016, Kaiyan Medical was the first red light therapy manufacturer to offer affordable, medical-grade devices to consumers for convenient, at-home use.

Relieve Pain And Discomfort

In humans, photobiomodulation is reportedly effective against various pain conditions, including mucositis, carpal tunnel syndrome, orthodontic pain, temporomandibular joint pain, neck pain, neuropathic pain from amputation, and menstrual cramps.

Red light therapy significantly reduces the severity of pain hypersensitivity while improving sensorimotor function.

These improvements are preceded by an anti-inflammatory microglia/macrophage cell population in the injury zone, thereby providing a lasting pain relief effect.

Red light therapy has been shown to yield effective pain relief via the modulation of multiple mechanisms:

  • Inhibitory cyclooxygenase and prostaglandins
  • Modulating nerve transmission
  • Increasing endorphins serotonin release
  • Stimulating metabolism
  • Activating peripheral opioid receptors
Repair Skin

Red light therapy is used for the rapid and safe healing of wounds from burns, surgery incisions, scars, diabetic neuropathy, ulcers, and bedsores.

Faster and better wound healing was one of NASA’s original findings and one of the key recognized uses for this technology. Red and near-infrared light promote beneficial effects during all four phases of the wound-healing process:

  • Coagulation
  • Inflammation
  • Migration
  • Remodeling

These processes are regulated by many growth factors connected with nitric oxide (NO) signaling release, which is modulated by light energy.

A major typical inhibiting factor for the body’s ability to recover from a wound is low oxygen flow. Therefore, the unique ability of red light to increase oxygen flow to the affected area has a massive effect on the healing process.

By reducing inflammation, oxygenation of the area, and formation of new blood vessels, a rapid healing process unfolds with less pain and scarring.

Red light energy may also reduce or prevent the need for pharmaceutical painkiller medication during the healing process.

Revive Immunity

If your body is energized on a cellular level and communication between the organ systems is efficient, your body will naturally develop disease resistance.

Your immune defense works to fend off bacteria and viruses all the time. Red light therapy boosts this system in several ways.

It releases nitric oxide and melatonin, which are involved in DNA repair and have a powerful antimicrobial effect.

It also works through a process known as hormesis. When red and near-infrared light is beamed into cells, it causes mild metabolic stress, which results in cells engaging their anti-inflammatory and antioxidant response.

In this way, the body is primed and ready to respond better to infections. Boosted immunity is also a natural consequence of other systemic effects of red light therapy.

Studies have shown a variety of benefits to the immune system:

  • Improved melatonin production
  • Improved antioxidant production
  • Increased micro-circulation enabling the transportation of immune cells.
  • Promotes activity in the lymph nodes
  • Increased NO levels
  • Better flow of neurotransmitters
  • Boosted collagen and elastin production
  • The more efficient function of cells and organelles
  • Boosts T cells pre-operatively
  • Improved thyroid function
Reduce Inflammation

Inflammation can be acute and topical ( short-lived, caused by accidents, sprains, and infections ), chronic and general ( long-term, caused by persistent conditions ).

While acute inflammation is a healthy physical healing response, chronic and general inflammation can be detrimental to health and often goes undetected.

Currently, the main treatment for inflammation in the body is NSAID or steroid drugs, both of which have side effects and disrupt the body's healing process. Red light therapy stimulates the body to activate its own healing mechanism, dramatically reducing the health risks associated with long term drug use.

Red light therapy works by decreasing the number of inflammatory cells, increasing fibroblast proliferation ( the cell that synthesizes the extra-cellular matrix and collagen ), stimulating angiogenesis ( the formation of new blood vessels ), and activating the body’s innate anti-inflammatory, antioxidant defenses.

The following conditions, associated with chronic and acute inflammation, are currently being investigated as highly promising targets for red light therapy.

  • Arthritis
  • Asthma
  • Sinusitis
  • Muscular sprains
  • Fibro-myalgia
  • Neuron inflammatory disorders such as Alzheimer’s
  • Irritable bowel syndrome and colitis
  • Rheumatic conditions
Regain Performance

Red light therapy has become a hot topic in sports and performance. Not only is it safe and non-toxic-it yields rapid and lasting results in many areas of application.

Besides the overwhelmingly beneficial effects on health overall, red light therapy supports muscle growth and repair by increasing the amount of ATP available, which allows for better performance and faster recovery.

Red light therapy used before training is known to prepare and strengthen the body and physical exertion to help with recovery.

Documented effects from red light therapy include:

  • Reducing DOMS ( Delayed Onset Muscle Soreness )
  • Greater endurance and performance
  • Improving sleep quality
  • Increasing sexual function and libido ( Including Testosterone )
  • Aiding weight loss
  • Boosting cognitive function
  • Reversing skin aging
  • Reducing cellulite
Red Light Therapy for Depression and Seasonal Affective Disorder

Seasonal affective disorder (SAD) is a type of depression that impacts at least 5% of Americans, especially in the winter months, when natural light exposure is lowest. SAD is also called seasonal depression, winter depression, or the winter blues.

Some people treat SAD symptoms with treatment options like bright white light therapies that mimic the sun’s light intensity at a bright time of day.

More researchers and physicians have used natural light treatments like red light therapy to help with natural light deficiency and the winter blues in recent years in conjunction with antidepressant medication and psychotherapy.

Who Uses Red Light Therapy?

In addition to the growing number of people using red light therapy devices in their home, red light therapy systems can be found in many professional and clinical settings:

Skincare Professionals: Red light therapy is a popular skin treatment among Hollywood celebrities for anti-aging, and it’s used by leading skincare professionals like estheticians and dermatologists to treat skin conditions and promote collagen production.

Health Practitioners: Red light therapy is an emerging subspecialty of medicine in a wide range of fields. From oncologists treating cancer side effects, to dentists reducing oral inflammation, to physicians treating mental health conditions, red light therapy is becoming more widespread in clinical practice.

Natural Health Experts: Leading voices in natural health and wellness like Dr. Sarah Ballantyne, Dave Asprey, and Ben Greenfield use red light therapy. So do Paleo and Keto health experts like Mark Sisson, Dr. Anthony Gustin, Luke Storey, and Robb Wolf.

Sports Medicine Pros: Light therapy companies work side by side with the National Association of Sports Medicine (NASM), and red light therapy is used to heal sports injuries by sports medicine professionals across the globe. Including the top trainers and doctors on the PGA Tour, like Dr. Troy Van Biezen and Dr. Ara Suppiah.

Elite Pro Athletes: Red light therapy is a popular training tool across pro sports, from NFL stars like Patrick Peterson, to UFC champs like Anthony Pettis, to gold medal gymnast Sanne Wevers.

Fitness & Training: World-class personal trainers like Lacey Stone and Jorge Cruise use red light therapy to both enhance performance and improve the muscle recovery process.

Supportive Cancer Care: The Multinational Association of Supportive Care in Cancer (MASCC) recommends red light therapy for the treatment of oral mucositis (OM), a common and debilitating symptom of cancer treatment.

Sources and References:

Klepeis N., Nelson W., Ott W., Robinson J., Tsang A., Switzer P., Behar J., Hern S., Engelmann W. “The National Human Activity Pattern Survey (NHAPS): a resource for assessing exposure to environmental pollutants”. Journal of Exposure Analysis and Environmental Epidemiology 2001.

Hamblin M. “Mechanisms and applications of the anti-inflammatory effects of photobiomodulation.” AIMS Biophys. 2017.

LED Lights Used in Plant Growth Experiments for Deep Space Missions. NASA.

Gál P,  Stausholm MB, et al. Should open excisions and sutured incisions be treated differently? A review and meta-analysis of animal wound models following low-level laser therapy. Lasers in Medical Science. 2018 Aug.

John Foley, David B Vasily, et al. 830 nm light-emitting diode (led) phototherapy significantly reduced return-to-play in injured university athletes: a pilot study. Laser Therapy. 2016 Mar.

Kim HK, Choi JH. Effects of radiofrequency, electroacupuncture, and low-level laser therapy on the wrinkles and moisture content of the forehead, eyes, and cheek. Journal of Physical Therapy Science. 2017 February.

Wunsch A and Matuschka K. A Controlled Trial to Determine the Efficacy of Red and Near-Infrared Light Treatment in Patient Satisfaction, Reduction of Fine Lines, Wrinkles, Skin Roughness, and Intradermal Collagen Density Increase. Photomedicine and Laser Surgery. Feb 2014.

Barolet D, Roberge CJ, et al. Regulation of skin collagen metabolism in vitro using a pulsed 660 nm LED light source: clinical correlation with a single-blinded study. Journal of Investigative Dermatology. 2009 December.

Morita T., Tokura H. “ Effects of lights of different color temperature on the nocturnal changes in core temperature and melatonin in humans” Journal of Physiological Anthropology. 1996, Sept.

Naeser M., Zafonte R, Krengel MH, Martin PI,  Frazier J, Hamblin MR, Knight JA, Meehan WP, Baker EH. “Significant improvements in cognitive performance post-transcranial, red/near-infrared light-emitting diode treatments in chronic, mild traumatic brain injury: open-protocol study”  Journal of Neurotrauma. 2014, June.

Liu KH, Liu D, et al. “Comparative effectiveness of low-level laser therapy for adult androgenic alopecia: a system review and meta-analysis of randomized controlled trials.” Lasers in Medical Science. 2019 Aug.

Gupta AK, Mays RR, et al. “Efficacy of non-surgical treatments for androgenetic alopecia: a systematic review and network meta-analysis.” JEADV. 2018 Dec.

Afifi L, Maranda EL, et al. “Low-level laser therapy as a treatment for androgenetic alopecia.” Lasers in Surgery and Medicine. 2017 Jan.

Hofling DB, Chavantes MC, et al. Low-level laser in the treatment of patients with hypothyroidism induced by chronic autoimmune thyroiditis: a randomized, placebo-controlled clinical trial. Lasers in Surgery and Medicine. May 2013.

Hofling DB, Chavantes MC, et al. Assessment of the effects of low-level laser therapy on the thyroid vascularization of patients with autoimmune hypothyroidism by color Doppler ultrasound. ISRN Endocrinology. 2012.

Hofling DB, Chavantes MC, et al. Low-level laser therapy in chronic autoimmune thyroiditis: a pilot study. Lasers in Surgery and Medicine. 2010 Aug.

Vladimirovich Moskvin S., Ivanovich Apolikhin O. Effectiveness of low level laser therapy for treating male infertility. Biomedicine (Taipei). 2018 June.

Ban Frangez H., Frangez I., Verdenik I., Jansa V., Virant Klun I. Photobiomodulation with light-emitting diodes improves sperm motility in men with asthenozoospermia. Laser in Medical Science, 2015 Jan.

Salman Yazdi, R., Bakhshi, S., Jannat Alipoor, F. et al. Effect of 830-nm diode laser irradiation on human sperm motility. Lasers Med Sci. 2014.

Chow KW, Preece D, Burns MW. Effect of red light on optically trapped spermatozoa. Biomedical Optics Express. 2017 Aug.

Preece D., Chow KW, Gomez-Godinez V., Gustafson K., et al. Red light improves spermatozoa motility and does not induce oxidative DNA damage. Scientific Reports. 2017 Apr.

American Psychiatric Association

Cassano P, Petrie SR, et al. Transcranial Photobiomodulation for the Treatment of Major Depressive Disorder. The ELATED-2 Pilot Trial. Photomedicine and Laser Surgery. 2018 October.

Barrett DW, et al. Transcranial infrared laser stimulation produces beneficial cognitive and emotional effects in humans. 2013 Jan.

Blanco NJ, Maddox WT, Gonzalez-Lima F. Improving executive function using transcranial infrared laser stimulation. Journal of Neuropsychology. 2017 Mar.

Paolillo FR, Borghi-Silva A, et al. New treatment of cellulite with infrared-LED illumination applied during high-intensity treadmill training. J Cosmet Laser Ther. 2011 Aug;13(4):166-71.

Caruso-Davis MK, Guillot TS, Podichetty VK, Mashtalir N, Dhurandhar NV, Dubuisson O, Yu Y. Efficacy of low-level laser therapy for body contouring and spot fat reduction. Obes Surg. 2011. Jun;21(6):722-9.

Jackson RF, Dedo DD, Roche GC, et al. Low-level laser therapy as a non-invasive approach for body contouring: a randomized, controlled study. Lasers in Surgery and Medicine. Dec 2009;41(10):99-809.

McRae E and Boris J. Independent evaluation of low-level laser therapy at 635 nm for non-invasive body contouring of the waist, hips, and thighs. Lasers in Surgery and Medicine. Jan 2013.

Avci P, Gupta A, et al. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Seminars in Cutaneous Medicine and Surgery. Mar 2013; 32(1): 41-52.

Light Therapy - The Future to Treat Addiction

Light Therapy - The Future to Treat Addiction

Based on the article of Joseph Nordqvist.

Using light therapy to eradicate addictive behaviors in rats.

They targeted light in the prelimbic region of the brain in rats who were addicted to cocaine. They found that after exposure to light therapy the rats demonstrated a significant reduction in addictive behavior.

The lead author of the study, Antonello Bonci, MD, scientific director of the intramural research program at the NIH’s National Institute on Drug Abuse (NIDA), said: “When we turn on a laser light in the prelimbic region of the prefrontal cortex, the compulsive cocaine seeking is gone.”

The study, published in Nature, highlights the role that the prefrontal cortex has in cocaine addiction and could help drive further testing in humans.

As one of the major health concerns in the U.S., cocaine addiction affects close to 1.2 million Americans and is responsible for a total of 482,188 emergency room visits every year.

One of the main problems with cocaine addiction is that people start taking the drug compulsively and lose the ability to function without it. About 80 percent of people who try to kick their cocaine addiction end up experiencing a relapse within six months.

There’s been a lot of focus on cocaine addiction, recently scientists at the University of Wisconsin-Milwaukee discovered a new potential means of developing a first-ever pharmacological treatment for cocaine addiction.

Eliminating addiction

Rats that were addicted to cocaine expressed low patterns of activity in their prefrontal cortex region of the brain – responsible for decision-making and behavioral flexibility.

Previous studies conducted on humans compulsively addicted to cocaine have found a similar pattern of low activity in this area of the brain as well.

The researchers measured the impact that laser light had on brain activity and addiction using a technique called optogenetics.

Through the use of genetic engineering they inserted proteins called rhodopsins into neurons located in the prefrontal cortex of rats. By activating this region of the brain with the laser they were able to turn the nerve cells on and off.

They observed that after turning the cells on there was a significant reduction in addictive behaviors in the rats compared to when the cells were turned off.

Among humans, the therapy would likely not involve the use of lasers, but instead the use of electromagnetic stimulation outside the scalp, with a technique called transcranial magnetic stimulation (TMS).

Other alternatives

A common beta blocker, propranolol, currently used to treat people with hypertension and anxiety, has shown to be effective in preventing the brain from retrieving memories associated with cocaine use in animal-addiction models, according to Devin Mueller, UWM assistant professor of psychology and a co-author with James Otis of the research.

"Right now, there are no FDA-approved medications that are known to successfully treat cocaine abuse," says Mueller, "only those that are used to treat the symptoms of cocaine withdrawal, which are largely ineffective at preventing relapse."

The effects of propranolol were long-lasting and could be permanent, he says, even without subsequent doses and even in the presence of stimuli known to induce relapse.

References:

https://www.medicalnewstoday.com/info/addiction/

Does Your Cat Get Depression in Winter? Light Therapy Can Solve it

Does Your Cat Get Depression in Winter? Light Therapy Can Solve it

A typical morning for our cats may involve purring, stretching, or meowing at the family members. After some time, the cat might retire to its favorite spot looking normal. But, do we really understand our felines? What if they were depressed? Would we understand why? Can we help them overcome the winter blues?

Cats are sensitive to changes in light, more so than people. Less lighting in the fall may cause a decrease in brain chemicals like serotonin. Given the inevitability of rain, snow, and cold weather in the fall, cats are often faced with a change of schedule.

If your cat is indoor/outdoor, he may become depressed during the winter months and shorter days. Even if your feline is indoor-only, lack of sunlight, less exercise during the fall, and longer periods of alone-time all contribute to the telltale symptoms of restlessness and depression of seasonal affective disorder, or SAD.

What causes SAD?

SAD in felines, as in people, is influenced by the amount of sunlight that your cat is exposed to. You may notice your cat appearing slower and gloomier during the winter months, yet when April and May arrive, he is more energetic and has a healthier appetite.

Lack of sunlight reduces the production of melatonin, which in turn leads to depression, drowsiness, and sometimes anxiety. It also results in low levels of serotonin, a hormone that serves as a neurotransmitter; cats may display symptoms of depression, aggression, and mood changes.

Restoring the chemical balance is not done easily, since serotonin cannot be given as a shot or in pill form. Many veterinarians turn to drugs — the same ones prescribed for humans.

If the idea of giving your cat pills or a serotonin reuptake inhibitor (SRI) makes your heartache, then it’s a good idea to learn about light therapy, which manipulates your cat’s environment to simulate the brightness of sunlight.

Using light therapy to treat SAD

Veterinarians often recommend light therapy to treat SAD. These natural, non-invasive, and low-cost treatments can cost less than a yearly supply of cat's food, and they let you maintain control over your pet’s emotional highs and lows.

In Kaiyan Medical, we recommend using light therapy for 30 minutes a day.

Like us, cats and dogs suffer from conditions such as inflammation, infections, and arthritis. And no matter how closely we watch them, they’ll scrape their legs, cut their pads, jar their shoulders and sprain their ankles.

How it works

So, how does red light actually help animals? Very simply, it delivers an energy boost to the cells, which provides wide-ranging health benefits.

Using LEDs or LASER diodes, LLLT penetrates your animal’s skin, blood, muscle, and bone using specific wavelengths of photons. Photoreceptors in your animal’s cells absorb this light energy, which enhances the healing process by giving the cells a boost of energy. Various wavelengths reach different layers of tissue. Red light, for example, is more efficiently absorbed by tissue rich in hemoglobin and is beneficial for healing surface wounds and stimulating acupressure points. Near-infrared light is able to pass through to deeper tissues such as tendons, ligaments, bones, joints, and muscles. Ideally, a combination of both red, green and near-infrared light is used in a light therapy session.


What else light therapy can do for your cat?

Because of the way it energizes the cells, red light can help with a number of health conditions in animals, including the following:

  • Joint pain
  • Osteoarthritis
  • Muscle soreness
  • Wounds and injuries
  • Rashes and infections
  • Inflammation

And there’s clinical data to prove it! In one study, horses that suffered from chronic back pain for years responded so well to red light therapy that in less than 3 months, over 70% were back to training and competing! (3) In addition, studies have also shown that horses treated with red light experience significantly faster tissue healing times.


Getting started

If you’re thinking of trying light therapy for your dog or cat, the first step is to ask yourself — and your vet — if it’s the right option for your companion’s needs. Light therapy can help with a wide variety of minor conditions. If your pet is experiencing something more severe, light therapy may be able to complement a more extensive treatment plan. In Kaiyan Medical we love animals and we want health and wellness for them as well.

References:

Does Your Cat Get Depression in Winter? Light Therapy Can Help | Catster
A typical morning for your cat may involve stretching, purring, or meowing the family awake at the break of dawn. After…www.catster.com

https://animalwellnessmagazine.com/light-therapy-for-dogs-and-cats/

https://www.healthline.com/health/depression/light-therapy

https://www.psychiatry.org/patients-families/depression/what-is-depression

http://www.slideshare.net/JLS10/light-therapy

Low-Intensity Light Therapy: Exploring the Role of Redox Mechanisms. Joseph Tafur, M.D. and Paul J. Mills, Ph.D.

Effect of NASA light-emitting diode irradiation on wound healing. J Clin Laser Med Surg. 2001

Treatment of chronic back pain in horses. Stimulation of acupuncture points with a low-powered infrared laser. Martin BB Jr. 1987.

Equine wound healing: influence of low-level laser therapy on an equine metacarpal wound healing model. Jann. 2012.

Effect of light-emitting diode (LED) therapy on the development of osteoarthritis (OA) in a rabbit model. Biomed Pharmacother. 2011

Low-level laser therapy reduces time to ambulation in dogs after hemilaminectomy: a preliminary study. Draper WE. 2012

Light Therapy Helping the Crisis that’s Being Ignored: PTSD

Light Therapy Helping the Crisis that’s Being Ignored: PTSD

Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a mental health condition that’s triggered by a terrifying event — either experiencing it or witnessing it. Symptoms may include flashbacks, nightmares, and severe anxiety, as well as uncontrollable thoughts about the event.

Most people who go through traumatic events may have temporary difficulty adjusting and coping, but with time and good self-care, they usually get better. If the symptoms get worse, last for months or even years, and interfere with your day-to-day functioning, you may have PTSD.

Getting effective treatment after PTSD symptoms develop can be critical to reduce symptoms and improve function.

PTSD symptoms are generally grouped into four types: intrusive memories, avoidance, negative changes in thinking and mood, and changes in physical and emotional reactions. Symptoms can vary over time or vary from person to person

The Light Helper, the EMDR Therapy

Eye Movement Desensitization and Reprocessing (EMDR) therapy is an interactive psychotherapy technique used to relieve psychological stress. It is an effective treatment for trauma and post-traumatic stress disorder (PTSD).

During EMDR therapy sessions, you relive traumatic or triggering experiences in brief doses while the therapist directs your eye movements.

EMDR is thought to be effective because recalling distressing events is often less emotionally upsetting when your attention is diverted. This allows you to be exposed to the memories or thoughts without having a strong psychological response.

Over time, this technique is believed to lessen the impact that the memories or thoughts have on you.

What are the Benefits of EMDR Therapy?

People who are dealing with traumatic memories and those who have PTSD are thought to benefit the most from EMDR therapy.

It’s thought to be particularly effective for those who struggle to talk about their past experiences.

Although there is not sufficient research to prove its effectiveness in these areas, EMDR therapy is also being used to treat:

How Does EMDR Therapy Work?

EMDR therapy is broken down into eight different phases, so you’ll need to attend multiple sessions. Treatment usually takes about 12 separate sessions.

Phase 1: History and treatment planning

Your therapist will first review your history and decide where you are in the treatment process. This evaluation phase also includes talking about your trauma and identifying potential traumatic memories to treat specifically.

Phase 2: Preparation

Your therapist will then help you learn several different ways to cope with the emotional or psychological stress you’re experiencing.

Stress management techniques such as deep breathing and mindfulness may be used.

Phase 3: Assessment

During the third phase of EMDR treatment, your therapist will identify the specific memories that will be targeted and all the associated components (such as the physical sensations that are stimulated when you concentrate on an event) for each target memory.

Phases 4–7: Treatment

Your therapist will then begin using EMDR therapy techniques to treat your targeted memories. During these sessions, you will be asked to focus on a negative thought, memory, or image.

Your therapist will simultaneously have you do specific eye movements. The bilateral stimulation may also include taps or other movements mixed in, depending on your case.

After the bilateral stimulation, your therapist will ask you to let your mind go blank and notice the thoughts and feelings you’re having spontaneously. After you identify these thoughts, your therapist may have you refocus on that traumatic memory, or move on to another.

If you become distressed, your therapist will help bring you back to the present before moving on to another traumatic memory. Over time, the distress over particular thoughts, images, or memories should start to fade.

Phase 8: Evaluation

In the final phase, you’ll be asked to evaluate your progress after these sessions. Your therapist will do the same.

How Effective is EMDR Therapy?

Multiple independent and controlled studies have shown that EMDR therapy is an effective treatment for PTSD. It’s even one of the Department of Veterans Affairs’ strongly recommended options to treat PTSD.

A 2012 study of 22 people found that EMDR therapy helped 77 percent of the individuals with a psychotic disorder and PTSD. It found that their hallucinations, delusions, anxiety, and depression symptoms were significantly improved after treatment. The study also found that symptoms were not exacerbated during treatment.

An older study trusted Source that compared EMDR therapy to typical prolonged exposure therapy, found that EMDR therapy was more effective in treating symptoms. The study also found that EMDR therapy had a lower dropout rate from participants. Both, however, offered a reduction in the symptoms of traumatic stress, including both anxiety and depression.

Several small studies have also found evidence that EMDR therapy is not only effective in the short term but that its effects can be maintained long term. One 2004 study evaluated people several months after they were given either “standard care” (SC) treatment for PTSD or EMDR therapy.

During and immediately after treatment, they noticed that EMDR was significantly more efficient in reducing symptoms of PTSD. During the three- and six-month follow-ups, they also recognized that participants maintained these benefits long after the treatment had ended. Overall, the study found that EMDR therapy gave people a longer-lasting reduction in symptoms than SC.

EMDR therapy has proven to be effective in treating trauma and PTSD. It may also be able to help treat other mental conditions like anxiety, depression, and panic disorders.

Some people may prefer this treatment to prescription medications, which can have unexpected side effects. Others may find that EMDR therapy strengthens the effectiveness of their medications. In Kaiyan Medical, we can help you create your own EMDR therapy device.

References
  • Berg DP, et al. (2012). Treating trauma in psychosis with EMDR: A pilot study. DOI:
    10.1016/j.jbtep.2011.09.011
  • Eye movement desensitization and reprocessing therapy. (2017).
    apa.org/ptsd-guideline/treatments/eye-movement-reprocessing.aspx
  • Hase M, et al. (2015). Eye movement desensitization and reprocessing (EMDR) therapy in the treatment of depression: A matched pairs study in an inpatient setting. DOI:
    10.1002/brb3.342
  • Ironson G, et al. (2002). Comparison of two treatments for traumatic stress: A community-based study of EMDR and prolonged exposure.
    ncbi.nlm.nih.gov/pubmed/11748600
  • Oren E, et al. (2012). EMDR therapy: An overview of its development and mechanisms of action. DOI:
    10.1016/j.erap.2012.08.005
  • Shapiro, F. (2014). The role of eye movement desensitization and reprocessing (EMDR) therapy in medicine: Addressing the psychological and physical symptoms stemming from adverse life experiences. DOI:
    10.7812/TPP/13–098

Breast Milk and Light Therapy, the Timekeepers

Breast Milk and Light Therapy, the Timekeepers

We live in a 24-hour environment, in which light and darkness follow a diurnal pattern. Our circadian pacemaker, the suprachiasmatic nuclei (SCN) in the hypothalamus, is entrained to the 24-hour solar day via a pathway from the retina and synchronizes our internal biological rhythms. Once we come to this world, one of the first things we need, is food. Naturally, as mammals(from Latin mamma “breast”), we feed ourselves from the breast. But, Human breast milk is more than a meal — it’s also a clock, providing time-of-day information to infants. The composition of breast milk changes across the day, giving energizing morning milk a different cocktail of ingredients than soothing evening milk. Researchers believe this “chrononutrition” may help program infants’ emerging circadian biology, the internal timekeeper that allows babies to distinguish day from night.

What happens, though, when babies drink milk that does not come directly from the breast but is pumped at different times of the day and stored in advance of feeding? Scientists have rarely considered the potential effects of “mistimed” milk on infants’ development, but the implications are potentially far-reaching.

In the same way, rhythmic variations in ambient illumination impact behaviors such as rest during sleep and activity during wakefulness as well as their underlying biological processes. The availability of artificial light has substantially changed the light environment, especially during the evening and night hours. Phones, laptops, ipads, and more around the babies. This may increase the risk of developing circadian rhythm sleep-wake disorders (CRSWD), which are often caused by a misalignment of endogenous circadian rhythms and external light-dark cycles. On the other hand, light can also be used as an effective and non-invasive therapeutic option with little to no side effects, to improve sleep, mood, and general well-being.

The architecture of the circadian system

The central master-clock in mammalian species is a paired structure in the hypothalamus with a volume of just about 0.25 mm3 per nucleus. Within the mammalian SCN, a molecular oscillator keeps the clock oscillating at its normal pace. The basis of this oscillator is two interconnected molecular feedback loops of clock gene expression, a detailed description of which is beyond the scope of this review though.

Successful interaction between body and environment however needs more than just a central clock; it also requires input pathways relaying information about the environment and the body to the SCN to achieve adequate entrainment as well as output pathways communicating timing information to the body to synchronize bodily processes with the circadian phase

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Sleep, eating, and energy levels all show circadian rhythms, which means they follow a daily cycle. As any parent who has sleepwalked through a 3 a.m. feeding knows, infants are not born with these rhythms fully set. Instead, their sense of day and night develops over the first weeks and months of life, thanks to cues like sunlight and darkness.

Babies vary: Some show predictable circadian fluctuations in hormones linked with alertness, sleep, and appetite, and can sleep for long stretches shortly after birth, whereas others seem to have their daily rhythms upside-down for months. Delays in the development of circadian biology can increase the risk of colic and lead to growth and feeding problems.

Breast milk may help program infant circadian rhythms, helping to explain why some parents of newborns enjoy long full nights of sleep, whereas others struggle to get their infants on a schedule.

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Dynamic Milk

Breast milk changes dramatically over the course of the day. For example, levels of cortisol — a hormone that promotes alertness — are three times higher in morning milk than in evening milk. Melatonin, which promotes sleep and digestion, can barely be detected in daytime milk, but rises in the evening and peaks around midnight.

Night milk also contains higher levels of certain DNA building blocks which help promote healthy sleep. Day milk, by contrast, has more activity-promoting amino acids than night milk. Iron in milk peaks at around noon; vitamin E peaks in the evening. Minerals like magnesium, zinc, potassium, and sodium are all highest in the morning.

Daytime milk may pack a special immune punch. Among mothers who provided researchers with milk samples across the first month postpartum, immune components — including key antibodies and white blood cells — looked higher in day milk compared to night milk. Another study found higher levels of a component important for immune system communication in day milk compared to night milk.

While it’s clear that milk changes over the course of the day, scientists know little about what this means for infant health. Researchers do know that the hormones and immune components in breast milk are passed along to infants and that infants are starting to develop and refine their own circadian rhythms during the first months of life. It’s plausible that the chronosignals in breast milk would help to shape infants’ own circadian biology. Differences in infant feeding patterns might help explain why there’s such variability in the development of these daily rhythms from one infant to another.

Fundamentals of light

To understand the effects of light on human physiology, it is important to understand light. Briefly, light is radiation in a specific range of the electromagnetic spectrum.

The spectrum of daylight, which is light from the sun filtered by the atmosphere is relatively broadband in its distribution. The availability of daylight depends on geographical location and season. In the timeframe of human evolution, it is a rather recent development that light can be available during all times of day through artificial light. Artificial light allows for illuminating indoor and outdoor spaces. It comes in many forms, e.g. incandescent, fluorescent, or light-emitting diode (LED) lighting.

While light generated by these technologies may all appear “white”, the underlying spectra are rather different.

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The reason why many different types of spectra might have the same appearance lies in the retina. Critically, different spectra, even if they create the same visual impression, may vary in their chronobiological effects on the circadian clock.

Recently, the Commission International de l’Eclairage (CIE), the international standard body for quantities related to light, issued a new standard containing a reference framework for quantifying the effects of light on non-visual functions.

Effects of LED light on the circadian clock

Two effects of light have been interrogated extensively in human circadian and sleep research: (1) the acute suppression of melatonin in response to light exposure and (2) the ability of light exposure to shift circadian phase.

The system mediating melatonin suppression has a spectral sensitivity that is broadly consistent with the spectral sensitivity of melanopsin. Similarly, the spectral sensitivity of circadian phase-shifting shows its maximal effect near the peak spectral sensitivity of melanopsin.

The effects of light on the phase of the circadian clock depend on the timing of light exposure. This is formally summarised in the phase response curve (PRC), which describes the amount of phase shift (in minutes and hours) achieved by exposure of light at a given circadian phase. Roughly speaking, the effect of morning light is that it advances the clock, while evening and night light delays the clock.

Both melatonin suppression and circadian phase shifts are modulated by the “photic history”, i.e. the amount of light seen during the day. The long-term adaptive influences of the “spectral diet” in the real world remain an important area of investigation.

Effects of light on sleep

The human sleep-wake cycle, which is periods of sleep during the night and wakefulness during the day, is one of the most prominent examples of a circadian behavioral pattern, especially for babies. It results from the interaction between two factors: the circadian drive for wakefulness and the homeostatic sleep pressure. The activity of the circadian pacemaker is aligned to counteract the increasing sleep pressure resulting from sustained wakefulness during the daytime. Likewise, the nocturnal increase in circadian sleep tendency counteracts the decrease in sleep propensity resulting from accumulated sleep thereby supporting a consolidated phase of nocturnal sleep.

Breast milk, artificial lighting, smartphones, and visual display units

In addition to natural daylight, babies are nowadays also exposed to a considerable amount of artificial light. This is particularly the case in the evening hours, i.e. when the circadian system is most sensitive to light-induced phase delays. Thereby, light therapy is more efficient to delay the timing of the circadian clock and thus sleep.

Even thou, mothers can label their milk with the time it was pumped and coordinate infant feedings to offer morning milk in the morning, afternoon milk in the afternoon, and night milk at night, they keep the constant use of visual units around the baby. The use for the babies is not different, entertainment as well

So, which one is better?

Is always about finding the balance. Rather than only use one of the methods, the responsible practice of light therapy and adequate alimentation of your newborn should be combined to get on track the circadian system

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Breastfeeding may improve nocturnal sleep and reduce infantile colic: Potential role of breast milk…

Melatonin is secreted during the night in adults but not in infants. It has a hypnotic effect as well as a relaxing…

doi.org

https://doi.org/10.2147/NSS.S125992

Breast Milk Is Teeming With Bacteria - That's Good for the Baby

Breast-fed milk may nourish a baby's microbiome in ways that bottled breast milk can't. In the earliest days after…

www.nytimes.com

https://doi.org/10.1542/peds.2008-1315c

The Sleeping Beauty Secret: The Red Light Therapy

The Sleeping Beauty Secret: The Red Light Therapy

Lack of sleep is a villain in America and Europe. Light intake is a big part of the problem. Over 65% of adults say they don’t get enough good sleep every week. Most people also don’t get nearly enough natural light for optimal health: the average American spends over 90% of their time indoors.

In addition to not getting enough natural light, people today are surrounded by artificial blue light from screens and overhead lighting. An overload of artificial blue light can cause headaches and make it harder to get to sleep and stay asleep. When we take in all that bright blue light from laptops, TVs, and phones, especially before we go to bed, our bodies get the signal that it's time to be awake, even if we're tired.

Melatonin is the naturally-occurring hormone that regulates sleep and wakefulness. Emerging research is showing that red light therapy treatments can help people produce more of their own, natural melatonin than exposure to other light sources like blue light. Red light therapy is natural light. It’s much less bright than blue light, with a lower color temperature than daytime sun, as the image above shows. Research has shown that red light doesn’t upset your sleep cycle like bright blue light. Red light therapy is showing great clinical results for people with insomnia and sleep disorders.

The light therapy is a simple, non-invasive treatment that delivers concentrated natural light to your skin and cells. Clinical research is showing that red light therapy can improve sleep quality and duration, and help people produce more of their own melatonin.

Light plays a major role in your sleep cycle. The body’s circadian clock interprets light as a sign of when to sleep and when to be awake. Artificial blue light from phones, computers, and other screens is extremely bright and can knock your circadian rhythm out of whack. Red light has the opposite effect: it’s ideal for evenings because it has a low color temperature—far lower than blue light and much closer to the natural sunset.

Red light therapy treatments are quick and simple: you just sit or stand in natural light for 5 to 15 minutes, ideally every day. This stimulates your mitochondria and gives your cells the natural light they need to make energy.

How Does Red Light Therapy Help You Sleep?

Natural light is a key ingredient for a healthy circadian rhythm and restful sleep. If you struggle to sleep, your light intake could be a big factor. Red light therapy delivers natural light like you’d get from the sun, but without UV rays, excess heat, or the need for sunny weather.

Red light therapy treatments supercharge your cells with the natural light they need to make more core ATP (adenosine triphosphate) energy. This helps your body run more efficiently, heal faster, and has shown great results for producing more natural melatonin and improving sleep disorders like insomnia.

Red light therapy treatments have shown great sleep results in a range of peer-reviewed clinical studies. One study on the sleep of pro basketball players showed that a 2-week course of red light therapy in the evening improved players’ sleep quality in the short term. Based on the results, the researchers suggested red light therapy would be a good non-invasive, drug-free solution to sleep struggles.

Overcoming Sleep Disorders with Red Light Therapy

Kaiyan's light therapy products are registered with the FDA as class II medical devices for the treatment of pain, strain, and inflammation. While the existing clinical research has been very positive for red light therapy and sleep, keep in mind that Kaiyan's devices are not cleared with the FDA for the treatment of various sleep disorders or melatonin.

Recent research on sleep disorders among people with migraine headaches has shown that red light therapy both decreased headache frequency, and was the only treatment that improved patients’ sleep disorders.

A 2014 study on cognitive function and traumatic brain injury (TBI) recorded that participants had significantly decreased episodes of post-traumatic stress disorder (PTSD), and improved sleep.

Analyzing patients’ electrical brain activity, a 2013 sleep study concluded that red light therapy was especially effective at helping people with sleep disorders fall asleep.


When I’m indoors training under the buzz of artificial lights, my body doesn’t get the natural light it needs. Add computers, cell phones, televisions, etc. and it’s easy to overload yourself with blue light. I used to have trouble sleeping after long training days, but since adding more natural light to my routine with red light therapy, I’ve been falling asleep as soon as I lie down, and I’ve been staying asleep all night.*

Sanne Wevers

Gold-Medal Winning Dutch Gymnast

Red Light Therapy, Sleep, Depression, and Seasonal Affective Disorder (SAD)

Research is showing how closely mood and sleep disorders are interconnected. Parts of the brain that regulate sleep have also been found to closely affect mood. A 2013 review concluded that “nearly all people suffering from mood disorders have significant disruptions in circadian rhythms and the sleep/wake cycle.”

This Greatist post on natural light and serotonin gives good background on the connections between natural light intake, mental health, and sleep. It also mentions using Kaiyan's red light therapy devices to get more natural light, even when you can’t get more sunlight.

Trouble sleeping is one of the most common symptoms of seasonal affective disorder, a type of depression most common in the darker winter months. Some physicians treating patients with mental health disorders have said red light therapy both improves mood, and helps people with depression get better sleep.

Sources and References:

Morita T., Tokura H. “ Effects of lights of different color temperature on the nocturnal changes in core temperature and melatonin in humans” Journal of Physiological Anthropology. 1996, September

Lirong Z., Phyllis Z. “Circadian Rhythm Sleep Disorders” Neurologic Clinics. 2012, November.

Color Temperature

The State of Sleep Health in America.

Klepeis N., Nelson W., et al. “The National Human Activity Pattern Survey (NHAPS): a resource for assessing exposure to environmental pollutants”. Journal of Exposure Analysis and Environmental Epidemiology 2001.

Sheppard A and Wolffsohn J. “Digital eye strain: prevalence, measurement and amelioration.” BMJ Open Ophthalmology. 2018 April.

Gooley, J., Chamberlain, K., Smith, K., Khalsa, S., et al. “Exposure to Room Light before Bedtime Suppresses Melatonin Onset and Shortens Melatonin Duration in Humans” J Clin Endocrinol Metab. 2011 Mar.

Hamblin M. “Mechanisms and applications of the anti-inflammatory effects of photobiomodulation”. AIMS Biophys. 2017.

Zhao J., Tian Y., Nie J., Xu J., Liu D. “Red light and the sleep quality and endurance performance of Chinese female basketball players” Journal of Athletic Training. 2012, November-December.

Loeb LM, Amorim RP, et al. “Botulinum toxin A (BT-A) versus low-level laser therapy (LLLT) in chronic migraine treatment: a comparison.” Arquivos de neuro-psiquiatria. 2018 Oct;76(10):663-667.

Naeser MA, Zafonte R, et al. “Significant improvements in cognitive performance post-transcranial, red/near-infrared light-emitting diode treatments in chronic, mild traumatic brain injury: open-protocol study.” Journal of Neurotrauma. 2014 Jun 1;31(11):1008-17.

Wu JH, Chang YC. Effect of low-level laser stimulation on EEG power in normal subjects with closed eyes. Evidence Based Complementary and Alternative Medicine. 2013; 2013:476565.

Vadnie C, and McClung C. Circadian Rhythm Disturbances in Mood Disorders: Insights into the Role of the Suprachiasmatic Nucleus. Neural Plasticity. 2017 November.

McClung C. How might circadian rhythms control mood? Let me count the ways. Biological Psychiatry. 2013 April.

Nutt D, Wilson S, et al. Sleep disorders as core symptoms of depression. Dialogues in Clinical Neuroscience. 2008 September.

Avci P, Gupta A, et al. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Seminars in Cutaneous Medicine and Surgery. Mar 2013.

Top Light Therapy Masks

Top Light Therapy Masks

Due COVID, everyone is obsessed with skin care these days, regular at-home routines have really leveled up, and no skin-care gadget is as intriguing as the LED light-therapy mask.

Celebrities are no longer the only ones who get to wear luminescent masks and haunt the public’s dreams by instagramming their LED selfies. There are now several regular-person versions available online, meaning anyone can harness the power of LED light, the green light for pain relief and slimming, the blue for bacteria-killing and red for collagen- and elastin-stimulating.

In Kaiyan Medical, we can create your FDA cleared light therapy mask based on your needs and market.

Here the top light therapy masks

MZ Skin Light-Therapy Golden Facial Treatment Device


Average price: $625

Buy here

If your skin is temperamental, it’s nice to have a well-rounded, high-performance mask on call. Designed to replicate MZ skin founder Dr. Maryam Zamani’s in-office treatments, it comes with five different light settings (red, blue, green, yellow, and white) so you can focus on anything from inflamed breakouts to the annoying scars and discoloration those pimples sometimes leave in their wake.


DMH Aesthetics Light Shield


Average price: $189

Buy here

Using this mask you can actually see out of it without lines obstructing your view. It’s designed to be very wearable and on-the-go, so you can continue doing whatever you’re doing while treating your skin. The Light Shield allows the wearer to enjoy RED, BLUE, and AMBER LED therapies. Specifically target post-treatment/facial redness with RED light, shown to boost circulation and speed healing

Project E Beauty Wireless LED Light Skin Rejuvenation Therapy Mask


Average price: $200

Buy here

This mask comes with seven different light colors to treat every skin-care issue imaginable on the face. Project E’s mask goes a step further with a bonus attachment for the neck, arguably the most overlooked part of skin-care routines. 99 + 40 LED lights cover your face & neck, upgraded to emit the most optimal wavelengths with 5 levels of intensity.


LG Derma Pra.L Mask


Average price: $480

Buy here

If you’re a K-beauty fan, there’s a Korean LED face mask just for you! This one comes from LG. All that appliance expertise has been channeled into a mask that hits the skin with red and infrared LED light in quick, nine-minute sessions focused on improving skin elasticity and brightness.


Dr. Dennis Gross Skin-Care SpectraLite Faceware Pro


Average price: $435

This LED mask from Dr. Dennis Gross is one of the more fashionable ones on the market. It comes with gold accents, 162 LED lights, and three treatment options to choose from: red-light therapy, blue-light therapy, or red and blue–light therapy.


TOP #1 — ADURO ® 7+1 LED FACE MASK


$399.00

Do you value personal comfort while lurking and skulking? This soft, silicone mask is less hockey goalie and more like an actual face mask that molds to your face shape for a more comfortable treatment. The aduro mask is the most advanced home-use facial mask based on light therapy.

  • 7 LED colors
  • Infra-Red Skin Boosting
  • 11 different treatments
  • 20 minutes
  • Non invasive
  • Clinically proven
  • Slows down the aging process
  • Prevents wrinkles
  • Soothes redness of the skin
  • Clears up skin imperfections
  • Stimulates cell rejuvenation
  • Improves skin tone

More information about Aduro here


Personal LED MASK - Aduro Australia
Personal LED MASK - Aduro Australia
Personal LED MASK - Aduro Australia
Personal LED MASK - Aduro Australia
Personal LED MASK - Aduro Australia

Personal LED MASK - Aduro Australia
Personal LED MASK - Aduro Australia
Personal LED MASK - Aduro Australia


Light Therapy: The Emerging Market

Light Therapy: The Emerging Market


Life without light is darkness. Light plays a vital role in our healthy life. Now the light is expanding the business scope in business for LIGHT THERAPY.

Light therapy also known as phototherapy is a simplified process, where the skin is precisely exposed before a light-emitting source on a routine. This light resembles natural light which helps to stimulate cells in the affected section.

Light Therapy has a notable history. It started back in 1903, when Niels Ryberg Finsen, developed a device that produced synthesized light. He was also awarded Nobel Prize in Medicine for this discovery.  Later in 1938, a hospital in Massachusetts performed effective testing on patients with colored lights.

Light therapy at the present considered as one of the standard of care for the treatment of various diseases by most of the healthcare professionals.

According to research, the global cosmetic products market is estimated to be valued at US$ 69 billion in the year 2025. One of the emerging business amongst the beauty and medical market is LIGHT THERAPY.

Light Therapy Market size was valued at USD 811.8 million in the year 2018 and is expected to witness a rise of 4.6% CAGR from 2019 to 2025.

Light Therapy Market
https://www.gminsights.com/industry-analysis/light-therapy-market

Drivers for the growth

The reason behind the growth of the market is driven by factors like the increase in dermatological disorders such as acne vulgaris, psoriasis, wrinkles. Light therapy market includes the usage of various lights like red, blue, green in dermatological as well as medical, health, sports industry too. The application of light therapy is vast and wide, which makes the market more diverge. It gives different companies an opportunity to participate and explore the market.

Additionally the rising disposable income, growth of upper middle-class population and increasing awareness of beauty products.

Also, modern users are more inclined towards the non-invasive treatment. With favorable reimbursement scenario in and advancement in the product technology, the liking of the light therapy has increased.

The Handheld devices for skin treatment (HDST) category held over 16.5% revenue share in 2018 and is now estimated to grow significantly by 2025. There is a wide adoption of handheld devices in home-care settings since the handheld devices have the ability to avoid the cell disruptions during light therapy treatment.


Germany Light Therapy Market Size, By Light Type, 2018 (USD Million)
https://www.gminsights.com/industry-analysis/light-therapy-market


Light Therapy Market, By Product

Handheld devices for skin treatment (HDST) segment held over 16.5% revenue share in 2018 and is projected to grow significantly by 2025. Ability of handheld devices to avoid cell disruption during light therapy device placement will upsurge its adoption in noninvasive interventions. Wide adoption of handheld devices in homecare settings will thus spur segment size.

Light visor segment is projected to witness robust CAGR of more than 4% over the forthcoming years. Adoption of portable lightening units such as light visors for effective patient management will accelerate segment growth over the coming years.

Light Therapy Market, By Application

Light therapy market is evolving day by day. In the past decade, there is a significant growth in this market. The wide range of applications in health, fitness, sports, beauty and medical field has increased the interest of buyers.

Sleeping disorder market segment was valued over USD 110 million in the year 2018 and is estimated to witness a similar trend during the upcoming years. The rising prevalence of sleep disorders such as Seasonal Affective Disorder (SAD), insomnia and jet lag and will uplift this segment growth. Additionally, the rising demand for light therapy for patients suffering from circadian rhythm will amplify the adoption of light therapy in the predictable future.

Another segmentation of application is the different forms where light therapy is being used like clinics, salons, home, hospitals etc. Dermatology clinics held more than 26% revenue share in 2018 as per a report. Also, the application at home is at soar. The end-users convenience is a major reason for the home-care setting application great market value which was around USD 495 million in 2018.

Light Therapy Market, By Light Type

Blue light segment accounted for more than 26% revenue share in 2018 and will exhibit substantial growth over the coming years. Extensive adoption of blue light in the treatment of sun damage as well as premalignant or malignant skin cancer should propel segment growth.

Red light segment is anticipated to witness around 4.5% CAGR over the forthcoming years. Wide application of red-light therapy in the treatment of orthopedic conditions such as joint pain, inflammation and arthritis will surge its adoption over the coming years.

Light Therapy Market, By End-use

Dermatology clinics held more than 26% revenue share in 2018 and will exhibit momentous growth over the forecast timeline. Rising incidence of skin disorders coupled with increasing demand for non-invasive procedures will foster segment growth during the forthcoming years.

Home-care settings segment was valued around USD 495 million in 2018 due to increasing patient preference towards home-care. Benefits offered by home-care settings such as quality treatment at affordable prices and reduced risk of dermatological clinics acquired infections will fuel the business growth.

Light Therapy Market, By Region

North America light therapy market will witness over 4% CAGR over the analysis timeline. Rising prevalence of skin disorders including eczema and skin cancer in North America is key factor driving light therapy business growth. Strong foothold of key industry players in the region will positively impact industry growth.

Asia Pacific light therapy market was valued more than USD 175 million revenue in 2018. Urbanization, changing lifestyle and increasing prevalence of depression and hypertension in the region will favor regional business growth. Increasing healthcare reforms in countries such as China will further drive Asia Pacific light therapy industry growth in the coming years.


Asia Pacific Light Therapy Market Size, By Country
https://www.gminsights.com/industry-analysis/light-therapy-market





References:

https://www.themarketreports.com/report/global-acne-light-therapy-devices-market-research-report

https://www.gminsights.com/industry-analysis/light-therapy-market

https://www.medgadget.com/2020/08/light-therapy-market-to-grow-at-a-cagr-of-5-1-by-2025-covid-19-impact-analysis-top-company-profile-global-share-industry-size-swot-analysis-regional-statistics.html

https://www.goldsteinresearch.com/report/cosmetics-industry-beauty-market-size-share-trends-demand

Can LED Light Give me The Perfect Skin?

Can LED Light Give me The Perfect Skin?

Following the article from the New York Times.

One day, shining light on your face may be the most important part of your skin care routine. We take a look at the newest devices.

The MMSphere, a ring of LED lights, casts a red glow over my face. It sits adjacent to my laptop so that as I write, research and procrastinate, I can simultaneously calm a fiery constellation of acne on my left cheek.

Red light’s anti-inflammatory and collagen-building effects on the skin are well documented. But this hands-free device, designed by Ellen Marmur, a dermatologist in New York, has settings for blue, green, amber and purple light too.

“It has just enough variety that people stay excited to use it,” Dr. Marmur said.

I, too, begin cocktailing. I bathe my face in blue light to kill acne bacteria while watching reruns, and immediately follow up with a FaceTime call to my mother, my face lit up in a bright green light to fight hyperpigmentation.

Skin care efficacy lives and dies by patient compliance. Most at-home LED skin care devices are small and hand-held, requiring time set aside to treat the entire face. People eventually stop using them.

Even with persistent acne as a motivator, I’ve always had trouble following LED protocols. The MMSphere ($495) is a big deal for me because it harnesses a powerful fix-everything-while-doing-nothing ease that makes it almost addictive. You actually want to use it.

“It makes people feel good, like they’re taking care of themselves,” Dr. Marmur said. “You can treat your skin while doing other things, so it’s easier to form the habit of doing it every day.”

Because, really, if we’re just sitting around — talking, eating, working — shouldn’t we be fixing our skin, too?

So How Does LED Work?

First, LED therapy is not the same as a laser treatment, which creates controlled damage to the skin to promote healing. The easiest way to understand the light-as-skin-care concept is to think of skin-friendly visible light as ultraviolet light’s benevolent counterpart.

In a process called photobiomodulation, light alters biological material; for example, UV rays from the sun change our skin in ways that can catalyze cancer and aging.

But some wavelengths of visible light alter our skin for the better, and light-emitting diodes (LED) are a source that delivers that energy.

Jared Jagdeo is an associate professor of dermatology and director of the Center for Phototherapy, SUNY Downstate Health Science University, where he studies LED therapy.

“You can alter the skin through photo-damaging with lasers, or photobiomodulation, which is a much more gentle way of changing the way the skin functions,” Dr. Jagdeo said. Red and blue light are the heavy hitters. He explained why red light in particular works so well.

“There’s a specific receptor in the mitochondria of the skin cells that red light specifically acts upon,” he said. “And that’s why red light is an ideal wavelength for changing the way the skin functions.”

Red light penetrates the skin deeper than other visible light and stimulates the mitochondria, which has an anti-inflammatory and rejuvenating effect. Collagen is built in the dermis, the skin is calmed, and wrinkles eventually fade.

Blue light doesn’t penetrate the skin as deeply but zaps acne-causing bacteria on the surface. The science on green light isn’t as solid, but in theory, it targets melanocytes, discouraging excess melanin production.

Rigorous independent studies have yet to be conducted, but Dr. Marmur did a very small clinical trial on green light for the MMSphere in which subjects self-reported a 32 percent decrease in “brown spots” after a week of green light treatment.

Is All of This Light Ok for my Eyes?

Eye safety is a valid concern, particularly because earlier this year Neutrogena recalled its LED mask over fears that it could cause eye injuries.

Brian S. Biesman, an assistant clinical professor of ophthalmology, dermatology and ENT at Vanderbilt University Medical Center in Nashville, said that most home devices aren’t powerful enough damage the eyes. The MMSphere comes with opaque goggles, but, Dr. Biesman said, the device is low energy, so it should be safe to use without them.

“Just normal blinking and eye movements should be sufficient to protect the eyes,” he said. “But never stare at a bright light source.”

More Thoughts

“As far as the F.D.A. is concerned, if I use CO2 laser resurfacing, it better work because of the amount of risk involved,” said Suzanne Kilmer, a clinical professor of dermatology at the UC Davis School of Medicine in Sacramento and director of the Laser and Skin Surgery Medical Group.

“Compare that to a home device,” Dr. Kilmer said. If it doesn’t kill you, blind you or make things much worse, it’s probably going to get approved. So it’s actually more incumbent upon the people selling home devices to show efficacy. You have to trust the people who are selling them.”

“LED is real, but it’s probably not optimized yet,” Dr. Kilmer said.

Many factors determine the amount of light your skin needs and receives: the strength of the light, the distance from source to skin, how long the light is used, and your skin color.

“Some of these lights on the market are very weak, and they may not have enough energy output to actually have a biological effect,” Dr. Jagdeo said. “Imagine a glow stick. It produces a color. But you could shine it on your face all day, and it’s not going to change the way your skin works.”

Furthermore, the medical community has yet to establish standard doses for treating conditions like hyperpigmentation and acne at home. Dr. Marmur based her MMSphere dosing on Blu-U, an in-office blue light that is commonly used as an alternative therapy for precancerous lesions.

“Consistent Sphere treatment for seven weeks will equal the energy given in the office with the Blu-U,” she said.

Another device, the Dr. Dennis Gross DRx SpectraLite FaceWare Pro, $435, emits red and blue light in a mask format, and each session is only three minutes. The mask’s LEDs are in contact with the skin, which may be a more effective treatment. Dr. Jagdeo said that you lose some energy on the way from device to skin, a potential downside of the MMSphere design.

“This is a tremendously undertapped area in medicine,” he said. “But LED light therapy is going to revolutionize the way home medical treatment is delivered for skin care over the next 10 to 15 years.”

Kaiyan Medical

In Kaiyan Medical you can create your own LED facial mask. We have developed Aduro mask who is one of the top facial masks in the beauty industry. Julia Roberts is a big fan of Aduro Mask. For more information visit https://www.aduroled.com/

Your Baby, Jaundice, and Light Therapy

Your Baby, Jaundice, and Light Therapy

Bilirubin is a yellow substance that comes from the normal breakdown of red blood cells. The liver removes bilirubin from the blood and passes it into the bowels so it can leave the body.

A newborn baby’s liver does not remove bilirubin, as well as an adult, does. Jaundice happens when bilirubin builds up faster than the liver can break it down and pass it from the body.

Most types of jaundice go away on their own. Others need treatment to lower bilirubin levels.

What Causes Jaundice?

Jaundice can be caused by different problems:

  • Physiological jaundice: The most common cause of newborn jaundice and occurs in more than 50% of babies. Because the baby has an immature liver. Jaundice first appears at 2 to 3 days of age. It usually disappears by 1 to 2 weeks of age, and the levels of bilirubin are harmless.
  • Breastfeeding jaundice: Breastfeeding jaundice may occur when your baby does not drink enough breast milk. It occurs in 5% to 10% of newborns.
  • Breast-milk jaundice: Breast-milk jaundice occurs in 1% to 2% of breast-fed babies. It is caused by a special substance that some mothers produce in their milk. This substance causes the baby’s intestine to absorb more bilirubin back into his body than normal. This type of jaundice starts at 4 to 7 days of age. It may last 3 to 10 weeks. It is not harmful.
  • Blood group incompatibility (Rh or ABO problems): If a baby and mother have different blood types, sometimes the mother produces antibodies that destroy the newborn’s red blood cells. This causes a sudden buildup of bilirubin in the baby’s blood. This serious type of jaundice usually begins during the first 24 hours of life. Rh problems formerly caused the most severe form of jaundice.

How Is Jaundice Diagnosed?

Doctors can tell if a baby has jaundice based on the yellowing of the skin and whites of the eyes. Usually, all newborns are checked for jaundice before leaving the hospital or birth center.

Babies with jaundice will get a blood test to check bilirubin levels. Sometimes, a light machine that measures bilirubin in the skin is used. But if the level is high, a blood test must confirm the result.

High bilirubin levels can lead to serious problems. So doctors carefully watch babies with jaundice.

Treatments for Jaundice

Some types of jaundice will disappear within a week or two without treatment. Other babies will require treatment because of the severity of jaundice.

Light treatment is the process of using light to eliminate bilirubin in the blood. The baby’s skin and blood absorb these light waves. These light waves are absorbed by your baby’s skin and blood and change bilirubin into products, which can pass through their system.

For many years, phototherapy treatment in the hospital has been provided by a row of lights or a spotlight suspended at a distance form a baby. This would provide light shining directly on an undressed baby (with a diaper on) whose eyes would need protection from the light with soft eye patches applied. Today, advancements in technology have led to a new phototherapy system that gives effective treatment without the inconveniences of conventional phototherapy treatment.

Which is the Vitamin that is not Normally Found in any Vegetarian Food? — Vitamin D

Which is the Vitamin that is not Normally Found in any Vegetarian Food? — Vitamin D

What would happen if you don’t get enough sun?

Which is the vitamin that is not normally found in any vegetarian food? Vitamin D.

Scientists have defined vitamins as organic (carbon-containing) chemicals that must be obtained from dietary sources because they are not produced by our bodies. Vitamins play a crucial role in our body’s metabolism, but only tiny amounts are needed to fill that role.

The discovery of Vitamin D was the culmination of a long search for a way to cure rickets in the 1920s, a painful childhood bone disease. Within a decade, the fortification of foods with vitamin D was on the way, and rickets became rare in the United States. However, research results suggest that vitamin D may have a role in other aspects of human health.

Vitamin Dit’s absent from all-natural foods except for fish and egg yolks, and even when it’s obtained from foods, it must be transformed by the body before it can do any good. That’s why the energy of the Sun is so important.

The sun’s energy turns a chemical in your skin into vitamin D3, which is carried to your liver and then your kidneys to transform it into active vitamin D.

The main cause of vitamin D deficiency is a lack of direct sunlight.
The main cause of vitamin D deficiency is a lack of direct sunlight

Humans, day by day, spend less time outdoors. Most people work indoors now, and many of our leisure pursuits occur in an indoor setting as well. What’s more, when we are outside, many people avoid the sun as much as possible. The result is the body not absorbing enough UVB rays to create the amount of vitamin D it requires. Often, symptoms of vitamin D deficiency are quite mild. When noticed, they mainly consist of:

  • Bone pain.
  • Chronic fatigue.
  • Frequent bone fractures.
  • Muddled thought processes.
  • Muscle weakness.
  • Soft or deformed bones.

Though you may not notice any symptoms, that doesn’t mean that vitamin D deficiency doesn’t present serious health risks. These include:

  • Children may develop severe asthma.
  • Immune system problems, raising your risk of infection.
  • Insulin resistance, impacting your body’s ability to process sugar and increasing your risk of diabetes, multiple sclerosis, and glucose intolerance.
  • Osteoporosis, a condition that includes brittle bones that are more likely to fracture.
  • Reduced cognitive function.
  • Rickets, a bone disease that causes soft bones and skeletal deformities.
Other conditions that would happen without enough sunlight

Less chance of having a baby

Without sunlight, there will be more melatonin in a woman’s body. This is a hormone that suppresses fertility, thereby reducing her chances of conceiving a baby. Moreover, women who get less sunlight reach their menopause earlier than those who are exposed to the Sun. Men can also suffer from a lack of sunlight; it directly influences testosterone levels.

Less chance of having a baby

Raw nerves

It’s believed that if children don’t get enough sunlight, they’ll be more at risk of developing multiple sclerosis, a disease of the central nervous system when they become adults.

All those aches and pains

Without sunlight, be prepared to get more pains all over your body. Sunlight helps to warm the body’s muscles and reduce the pain caused by inflammatory conditions such as arthritis.

No sunny emotions

Image for post

Without sunlight, we would be forever stuck with the seasonal affective disorder (SAD), commonly known as the winter blues. It’s a form of depression that is specifically caused by a lack of sunlight. Artificial light cannot fully replace natural sunlight.

Recent evidence suggests that vitamin D may help prevent many disorders, such as diabetes, multiple sclerosis, rheumatoid arthritis, chronic obstructive pulmonary disease, asthma, bronchitis, premenstrual syndrome, increased blood pressure, strokes and heart attacks, and even cancer. Low serum vitamin D levels are also associated with being overweight, abdominal obesity, metabolic syndrome, stroke, and diabetes. In addition, having lower blood vitamin D levels for a long period is associated with increased heart attacks and all-cause mortality.

In Kaiyan medical, we believe in the benefits of light. We believe in healing without chemicals. With our lights, we want you to have the best version of yourself. More at kaiyanmedical.com

References:

Holick MF (March 2006). “High prevalence of vitamin D inadequacy and implications for health”. Mayo Clinic Proceedings. 81 (3): 353–73. doi:10.4065/81.3.353. PMID 16529140.

Holick MF (December 2004). “Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease”. The American Journal of Clinical Nutrition. 80 (6 Suppl): 1678S–88S. doi:10.1093/ajcn/80.6.1678S. PMID 15585788.

Weick MT (November 1967). “A history of rickets in the United States”. The American Journal of Clinical Nutrition. 20 (11): 1234–41. doi:10.1093/ajcn/20.11.1234. PMID 4862158.

Aghajafari F, Nagulesapillai T, Ronksley PE, Tough SC, O’Beirne M, Rabi DM (March 2013). “Association between maternal serum 25-hydroxyvitamin D level and pregnancy and neonatal outcomes: systematic review and meta-analysis of observational studies”. BMJ. 346: f1169. doi:10.1136/bmj.f1169. PMID 23533188.

Palacios C, De-Regil LM, Lombardo LK, Peña-Rosas JP (November 2016). “Vitamin D supplementation during pregnancy: Updated meta-analysis on maternal outcomes”. The Journal of Steroid Biochemistry and Molecular Biology. 164: 148–155. doi:10.1016/j.jsbmb.2016.02.008. PMC 5357731. PMID 26877200.

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The Beauty and the Beam: the Magic of the Red Light Therapy.

The Beauty and the Beam: the Magic of the Red Light Therapy.

Skeptical

While I was initially skeptical at the 8-minute treatment, after I started to calm my mind, I fell in love with it. From age spots, to dry skin and acne, it cures whatever ails you. Could sound like a magic potion from a princess but is just light therapy. Before you go with the “What the…?” face, it’s only a matter of time before it shows up in most of the celebrities’ social media.

Most of our users describe it as

“warm and relaxing, and allows you to go into a meditative state of mind.”

LED light therapy has an established history of skin uses. The U.S. Navy SEALs began using it in the 1990s to help heal wounds quickly and to help regenerate damaged muscle tissues.

Since then, the treatment has been researched for different situations in aesthetics. It’s mainly noted for increasing collagen and tissues.

There are different frequencies, or wavelengths, used with LED light treatment. These include red and blue light frequencies, which don’t contain ultraviolet rays and are readily absorbed into the skin.

Light therapy

Different than Daylight

Unlike ultraviolet rays from the sun which damage the DNA of skin cells, “light emitted in this spectrum is perfectly safe,” said Dr. Susan Bard, a board-certified dermatologist based in New York City.

That means there’s no tanning or burning when you’re exposed to red light. Its effects happen deep inside at the cellular level. All living things need to make ATP cellular energy to function and survive, and nearly all living things rely on natural light to power this process in our cells every day. Red and near-infrared wavelengths of natural light stimulate the mitochondria in your cells, the powerhouses responsible for taking light, oxygen, and the food we eat — and turning it into usable energy for our bodies through the process of cellular respiration.

Light therapy

Uses of Red Light

Red light therapy has been used to treat or improve the following:

  • pain
  • inflammation
  • healing
  • tissue regeneration
  • autoimmune diseases
  • brain disorders
  • athletic performance
  • eyesight
  • heating
  • cancer therapy side effects

“The number of conditions red light can treat is ‘continuously expanding”

said Michael R. Hamblin, PhD, a principal investigator at the Wellman Center for Photomedicine at Massachusetts General Hospital and associate professor of dermatology at Harvard Medical School.

The Short Version

Light therapy delivers safe, concentrated wavelengths of natural light to your skin and cells, with no chemicals, UV rays, or excess heat. These red and near-infrared wavelengths of light stimulate the mitochondria in your cells similar to natural sunlight, reducing oxidative stress, and increasing circulation, so your body is able to make more core energy to power itself.

In Kaiyan medical, we believe in the benefits of light. We believe in healing without chemicals. With our lights, we want you to have the best version of yourself.