Light Therapy & Kids with Autism

Autism Spectrum Disorder (ASD)

Autism spectrum disorder (ASD) is a complicated syndrome of nervous system development characterized clinically by language impairment, dysfunction in social engagement, language, stereotypical movements and behaviors, and various cognitive deficits.

Light can have a deep influence on people. Different colored lighting can affect our moods, and a lack of natural light can cause depression. This especially applies to those with autism.

Children with autism are especially susceptible to mood changes due to lighting. Lights with mellow colors, like blue, can help a child relax and become creative. Flickering, humming, or harshly colored lights, on the other hand, can confuse and even hurt them. For this reason, it is important that lighting is controllable and monitored in the child’s rooms.

In addition to manufactured lighting, natural lighting also has its effects. Natural lighting has proven benefits for autistic children. Seasonal affective disorder, or SAD, caused by a lack of natural light during winter months, can foster behavioral issues and depression. Natural light has been shown to relieve these symptoms.

Light therapy has been used for more than to relieve these symptoms. Natural light can help regulate a child’s circadian rhythms. These rhythms govern our body’s “internal master clock.” For example, they tell us when it’s time to sleep. A lack of natural light can cause our rhythms to fall out of sync. Therefore, treatment can make a child with insomnia fall asleep without aids and become more alert during the day, among other benefits.

The best time for treatment is in the morning, soon after the child rises. Even spending just 30 minutes in the light can improve their mood and sleeping habits. 30 minutes might not be possible initially, so while building up to it, another session in the afternoon can help. But therapy at night can have negative effects, worsening a child’s routine and making it harder to fall asleep.

Clinical Study

A study examined the efficacy of low-level laser therapy, a form of photobiomodulation, to treat irritability associated with an autistic spectrum disorder in children and adolescents aged 5–17 years. Twenty-one of the 40 participants received eight 5-min procedures administered to the base of the skull and temporal areas across a 4-week period (test, i.e., active treatment participants). All the participants were evaluated with the Aberrant Behavior Checklist (ABC), with the global scale and five subscales (irritability/agitation, lethargy/social withdrawal, stereotypic behavior, hyperactivity/noncompliance, and inappropriate speech), and the Clinical Global Impressions (CGI) Scale including a severity-of-illness scale (CGI-S) and a global improvement/change scale (CGI-C). The evaluation took place at baseline, week 2 (interim), week 4 (endpoint), and week 8 (post-procedure) of the study. The adjusted mean difference in the baseline to study endpoint change in the ABC irritability subscale score between test and placebo participants was -15.17 in favor of the test procedure group. ANCOVA analysis found this difference statistically significant (F = 99.34, p < 0.0001) compared to the baseline ABC irritability subscale score. The study found that low-level laser therapy could be an effective tool for reducing irritability and other symptoms and behaviors associated with the autistic spectrum disorder in children and adolescents, with positive changes maintained and augmented over time.

A significant literature exists on Low-Level Laser Therapy (LLLT) ability, a form of photobiomodulation, to penetrate the skull in both diagnostic and therapeutic applications. Low energy laser passes the skull, and a therapeutic effect likely exists. Low energy laser systems employ the so-called quantum optical induced transparency (QIT)-effect. This effect, electromagnetically induced transparency (EIT), controls optical properties of dense media and can enhance transparency contrast by a factor of five. Therefore, the skull, spine, or joints can be penetrated even with moderate intensity light. Due to the QIT effect, the radiation should reach deep tissue layers in muscles, connective tissue, and even bone, enabling noninvasive transcranial treatments.

Conclusions

The study’s findings strongly illustrate that not only does the application of light therapy affect a sizable, statistically significant, and clinically meaningful improvement in all of the key evaluable behaviors characteristic of autism disorder in children and adolescents, but it continues to affect a progressive and meaningful improvement in symptoms for up to 6 months following completion of the procedure administration protocol.

LLLT can achieve a therapeutic effect by employing non-ionizing light, including lasers, light-emitting diodes, or broadband light in the visible red (600–700 nm) and near-infrared (780–1100 nm) spectra. LLLT is a non-thermal process beginning when a chromophore molecule is exposed to a suitable wavelength of light. Chromophores are responsible for the color associated with biological compounds such as hemoglobin, myoglobin, and cytochromes. When a chromophore absorbs a photon of light, an electron transits to an excited state. The physiologic effects of LLLT occur when photons dissociate the inhibitory signaling molecule, nitric oxide (NO), from cytochrome-C-oxidase, increasing: electron transport, mitochondrial membrane potentials production of mitochondrial products such as ATP, NADH, RNA, and cellular respiration. The leading hypothesis is that the photons dissociate inhibitory nitric oxide from the enzyme, leading to increased electron transport, mitochondrial membrane potential, and ATP production.

References

1. Abbott, A. E., A. C. Linke, A. Nair, A. Jahedi, L. A. Alba, C. L. Keown, I. Fishman, and R. A. Muller. 2018. 'Repetitive behaviors in autism are linked to imbalance of corticostriatal connectivity: a functional connectivity MRI study', Soc Cogn Affect Neurosci, 13: 32-42.
2. Batista-Garcia-Ramo, K., and C. I. Fernandez-Verdecia. 2018. 'What We Know About the Brain Structure-Function Relationship', Behav Sci (Basel), 8.
3. Brown, E. C., M. G. Aman, and S. M. Havercamp. 2002. 'Factor analysis and norms for parent ratings on the Aberrant Behavior Checklist-Community for young people in special education', Res Dev Disabil, 23: 45-60.
4. de Freitas, L. F., and M. R. Hamblin. 2016. 'Proposed Mechanisms of Photobiomodulation or Low-Level Light Therapy', IEEE J Sel Top Quantum Electron, 22.
5. Demirtas-Tatlidede, A., A. M. Vahabzadeh-Hagh, M. Bernabeu, J. M. Tormos, and A. Pascual-Leone. 2012. 'Noninvasive brain stimulation in traumatic brain injury', J Head Trauma Rehabil, 27: 274-92.
6. Emelyanov, A. N., and V. V. Kiryanova. 2015. 'Photomodulation of proliferation and differentiation of stem cells by the visible and infrared light', Photomed Laser Surg, 33: 164-74.
7. Freitas, L. F., M. R. Hamblin, F. Anzengruber, J. R. Perussi, A. O. Ribeiro, V. C. A. Martins, and A. M. G. Plepis. 2017. 'Zinc phthalocyanines attached to gold nanorods for simultaneous hyperthermic and photodynamic therapies against melanoma in vitro', J Photochem Photobiol B, 173: 181-86.
8. Hamblin, M. R. 2018. 'Photobiomodulation for traumatic brain injury and stroke', J Neurosci Res, 96: 731-43.
9. Heiskanen, V., and M. R. Hamblin. 2018. 'Photobiomodulation: lasers vs. light emitting diodes?', Photochem Photobiol Sci, 17: 1003-17.
10. Henderson, T. A., and L. D. Morries. 2015. 'Near-infrared photonic energy penetration: can infrared phototherapy effectively reach the human brain?', Neuropsychiatr Dis Treat, 11: 2191-208.
11. Hiwaki, O., and H. Miyaguchi. 2018. 'Noninvasive measurement of dynamic brain signals using light penetrating the brain', PLoS One, 13: e0192095.
12. Huang, Y. Y., A. Gupta, D. Vecchio, V. J. de Arce, S. F. Huang, W. Xuan, and M. R. Hamblin. 2012. 'Transcranial low level laser (light) therapy for traumatic brain injury', J Biophotonics, 5: 827-37.
13. Jiang, P., V. Vuontela, M. Tokariev, H. Lin, E. T. Aronen, Y. Ma, and S. Carlson. 2018. 'Functional connectivity of intrinsic cognitive networks during resting state and task performance in preadolescent children', PLoS One, 13: e0205690.
14. Kaat, A. J., L. Lecavalier, and M. G. Aman. 2014. 'Validity of the aberrant behavior checklist in children with autism spectrum disorder', J Autism Dev Disord, 44: 1103-16.
15. Karabekiroglu, K., and M. G. Aman. 2009. 'Validity of the aberrant behavior checklist in a clinical sample of toddlers', Child Psychiatry Hum Dev, 40: 99-110.
16. Khuman, J., J. Zhang, J. Park, J. D. Carroll, C. Donahue, and M. J. Whalen. 2012. 'Low-level laser light therapy improves cognitive deficits and inhibits microglial activation after controlled cortical impact in mice', J Neurotrauma, 29: 408-17.
17. Kotkowski, E., L. R. Price, P. Mickle Fox, T. J. Vanasse, and P. T. Fox. 2018. 'The hippocampal network model: A transdiagnostic metaconnectomic approach', Neuroimage Clin, 18: 115-29.
18. Lapchak, P. A., and P. D. Boitano. 2016. 'Transcranial Near-Infrared Laser Therapy for Stroke: How to Recover from Futility in the NEST-3 Clinical Trial', Acta Neurochir Suppl, 121: 7-12.
19. Leisman, G., C. Machado, Y. Machado, and M. Chinchilla-Acosta. 2018. 'Effects of Low-Level Laser Therapy in Autism Spectrum Disorder', Adv Exp Med Biol.
20. Machado, C., M. Estevez, G. Leisman, R. Melillo, R. Rodriguez, P. DeFina, A. Hernandez, J. Perez-Nellar, R. Naranjo, M. Chinchilla, N. Garofalo, J. Vargas, and C. Beltran. 2015. 'QEEG spectral and coherence assessment of autistic children in three different experimental conditions', J Autism Dev Disord, 45: 406-24.
21. Machado, C., M. Estevez, R. Rodriguez, and G. Leisman. 2017. 'Letter re: The autism "epidemic": Ethical, legal, and social issues in a developmental spectrum disorder', Neurology, 89: 1310.
22. Machado, C. J., and J. Bachevalier. 2003. 'Non-human primate models of childhood psychopathology: the promise and the limitations', J Child Psychol Psychiatry, 44: 64-87.
23. Machado, C., R. Rodriguez, M. Estevez, G. Leisman, R. Melillo, M. Chinchilla, and L. Portela. 2015. 'Anatomic and Functional Connectivity Relationship in Autistic Children During Three Different Experimental Conditions', Brain Connect, 5: 487-96.
24. Moreira, M. S., I. T. Velasco, L. S. Ferreira, S. K. Ariga, F. Abatepaulo, L. T. Grinberg, and M. M. Marques. 2011. 'Effect of laser phototherapy on wound healing following cerebral ischemia by cryogenic injury', J Photochem Photobiol B, 105: 207-15.
25. Morries, L. D., P. Cassano, and T. A. Henderson. 2015. 'Treatments for traumatic brain injury with emphasis on transcranial near-infrared laser phototherapy', Neuropsychiatr Dis Treat, 11: 2159-75.
26. Naeser, M. A., P. I. Martin, M. D. Ho, M. H. Krengel, Y. Bogdanova, J. A. Knight, M. K. Yee, R. Zafonte, J. Frazier, M. R. Hamblin, and B. B. Koo. 2016. 'Transcranial, Red/Near-Infrared Light-Emitting Diode Therapy to Improve Cognition in Chronic Traumatic Brain Injury', Photomed Laser Surg, 34: 610-26.
27. Poiani, Gdcr, A. L. Zaninotto, A. M. C. Carneiro, R. A. Zangaro, A. S. I. Salgado, R. B. Parreira, A. F. de Andrade, M. J. Teixeira, and W. S. Paiva. 2018. 'Photobiomodulation using low-level laser therapy (LLLT) for patients with chronic traumatic brain injury: a randomized controlled trial study protocol', Trials, 19: 17.
28. Primo, F. L., M. B. da Costa Reis, M. A. Porcionatto, and A. C. Tedesco. 2011. 'In vitro evaluation of chloroaluminum phthalocyanine nanoemulsion and low-level laser therapy on human skin dermal equivalents and bone marrow mesenchymal stem cells', Curr Med Chem, 18: 3376-81.
29. Raj, A., and F. Powell. 2018. 'Models of Network Spread and Network Degeneration in Brain Disorders', Biol Psychiatry Cogn Neurosci Neuroimaging, 3: 788-97.
30. Ranasinghe, K. G., L. B. Hinkley, A. J. Beagle, D. Mizuiri, S. M. Honma, A. E. Welch, I. Hubbard, M. L. Mandelli, Z. A. Miller, C. Garrett, A. La, A. L. Boxer, J. F. Houde, B. L. Miller, K. A. Vossel, M. L. Gorno-Tempini, and S. S. Nagarajan. 2017. 'Distinct spatiotemporal patterns of neuronal functional connectivity in primary progressive aphasia variants', Brain, 140: 2737-51.
31. Rochkind, S., A. Shahar, M. Amon, and Z. Nevo. 2002. 'Transplantation of embryonal spinal cord nerve cells cultured on biodegradable microcarriers followed by low power laser irradiation for the treatment of traumatic paraplegia in rats', Neurol Res, 24: 355-60.
32. Rojahn, J., and W. J. Helsel. 1991. 'The Aberrant Behavior Checklist with children and adolescents with dual diagnosis', J Autism Dev Disord, 21: 17-28.
33. Salehpour, F., J. Mahmoudi, F. Kamari, S. Sadigh-Eteghad, S. H. Rasta, and M. R. Hamblin. 2018. 'Brain Photobiomodulation Therapy: a Narrative Review', Mol Neurobiol, 55: 6601-36.
34. Scherman, M., O. S. Mishina, P. Lombardi, E. Giacobino, and J. Laurat. 2012. 'Enhancing electromagnetically-induced transparency in a multilevel broadened medium', Opt Express, 20: 4346-51.
35. Shen, C. C., Y. C. Yang, T. B. Huang, S. C. Chan, and B. S. Liu. 2013. 'Neural regeneration in a novel nerve conduit across a large gap of the transected sciatic nerve in rats with low-level laser phototherapy', J Biomed Mater Res A, 101: 2763-77.
36. Shen, C. C., Y. C. Yang, and B. S. Liu. 2013. 'Effects of large-area irradiated laser phototherapy on peripheral nerve regeneration across a large gap in a biomaterial conduit', J Biomed Mater Res A, 101: 239-52.
37. Stevens, E. J., and D. R. Tomlinson. 1995. 'Effects of endothelin receptor antagonism with bosentan on peripheral nerve function in experimental diabetes', Br J Pharmacol, 115: 373-9.

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The Road to Remission: Light Therapy Proves Effective for Cancer Survivors

It's common to describe cancer as something you battle, because dealing with the disease feels truly like something you have to conquer. It's a moment in life that forever changes you and the lives around you. Apart from physical health, cancer affects your mental health equally. It brings in a wide range of emotions and feelings that a person has probably never had to deal with until that moment. Up until the condition, people deal with hardships, but not like this. 

While getting used to intense medical treatments and significant lifestyle changes, these situational adjustments all fall heavy on the shoulders of those who are sick. 

Luckily beating the beast is possible. Fighting off and beating cancer can be done. 

The most common treatment and way of going against cancer is through chemotherapy. Chemotherapy is a form of therapy that works throughout the whole body, targeting the cells that divide equally fast during cancer. Certain chemotherapy drugs could lead to the damage of cells in your heart. Chemotherapy can also increase your odds of getting heart problems, such as weakening the muscle (cardiomyopathy) and general problems with your cardiac rhythm (arrhythmia).

It takes a long time for the body to heal and regenerate post-treatment, and sometimes an even longer time before people can feel like themselves again. Putting the body back in optimal health is crucial. This may be easier said than done, and maintaining the health of your immune system isn't something to take lightly. 

The immune system gets stronger over time, but it has to stay strong; which is the bigger challenge and one that, if failed, struggles to return. It is possible to upkeep the immune system, and many are looking towards non-invasive therapeutic options in this realm. For cancer survivors, many struggle to determine what’s next in their help journey. For many, they are seeking out non-invasive and non-pharmaceutical treatments as they enter remission, which is where light therapy comes in. 

The types of light therapy range from aiding in superficial skin problems and hair regrowth, to deeper cellular healing from within. The way that light therapy works is via our powerful cells. It targets and penetrates the cells, rejuvenating and provoking acceleration at the reproduction stage. Higher cell production equates to a faster rejuvenation of cells, which provides the body with stronger and healthier cells overall. The higher the cell count, the healthier the body, since light therapy helps with cellular healing via genetic material and ATP—the powerhouse of our entire system. 

Light therapy and cancer may sound completely unrelated; however, you may want to rethink that; in addition to help stimulate healthy cell turnover, light therapy can also be a tremendous aid in sleep disorders. During sleep, our bodies are naturally healing and in the process of regeneration, however, cancer, and cancer treatments and medications, can lead to a very disrupted circadian rhythm

Together, disturbance of circadian activity in adult or pediatric cancer patients has been associated with greater fatigue, poorer quality of life, impaired immune function, lower responsiveness to chemotherapy, earlier relapse, and higher risk of death than patients with robust (healthy) circadian activity rhythms.

Infrared light therapy has been studied for a while in cancer patients; one study, in particular, indicates that light therapy works on the corrupted genetic material that could kill cancer cells. In the study, circadian rhythms became more synchronized, and quality of life was better within the trial testing of light therapy's effect on cancer. 

Light therapy has a multitude of benefits for cancer survivors, providing them a non-invasive, non-pharmaceutical treatment that works at the cellular level. It can repair and maintain health just by improving circadian rhythms that lead to a healthier body and stronger immune system. And this is crucially important since sleep is one of the most important elements in staying strong and healthy post-recovery.

Kayian's light therapy devices are MDA-certified and FDA-certified, and are perfect for in-clinic or at-home treatments. We offer you the opportunity to treat yourself, or your patients, by stepping out of the traditional medical options, a place where many often feel powerless. Supplementing light therapy in treatment and recovery has proven to be a life-changing, safe, and powerful modality.

College Students use Light Therapy to Improve Seasonal Affective Disorder (SAD)

The life of a college student is taxing, to say the least. It's likely the first time you're doing something on your own, and are responsible for yourself, your schedule and lifestyle. For some, this is the most liberating time; for others, it’s incredibly overwhelming. However, there's a general agreement that college students all go through difficult times. 

Whether still living with parents or sharing a dorm or space with roommates, college students are immersed in an entirely new life experience. Classes are challenging and students struggle with getting their work done while maintaining a social life, and perhaps a job. The level of pressure to succeed is very demanding, and this can cause negatively associated thoughts, leading to stress. Eating habits change and alter, usually for the worst, not to mention that the new sense of freedom can be chaotic for many young adults. 

Taking care of yourself is the number one priority, and when learning to deal with the new load of responsibility, college students often get sidetracked. Health and self-care get only an ounce of attention and not nearly as much as it should. While many students think it takes a lot of effort, just starting small shows results. 

Stress is the precursor of everything in our body, and leads to all sorts of illness and disorders. It's pretty common for college students to experience stress; more than 40% of students claimed to have experienced above-average stress levels, with it getting worse during exam periods and the winter season, when even more time is spent indoors. All of this, compounded by a pandemic and social distancing, makes for extremely challenging circumstances for college students today.

Now, colleges such as the University of Iowa are turning to light therapy to help get students the light they need to continue thriving. 

Seasonal affective disorder (SAD) is a mood disorder that occurs annually, generally in fall and early winter, and ends in sunnier and warmer months of spring and early summer. However, it’s worth noting that it’s not a perfect formula; there have been reported cases of the opposite, where a person starts experiencing the disorder spring or summer, and it only ends with the arrival of fall/winter. 

SAD can affect 11 million people in the U.S. each year, and 25 million more may have a milder form of the same disorder, also known as winter blues. Depression and anxiety affect 40 million adults in America, while only 36.9% receive the proper care for these mental health conditions

And, SAD’s symptoms can look and feel much like depression. It causes you to sleep more and gives you symptoms that look like other disorders such as chronic fatigue syndrome, under-active thyroid, low blood sugar, viral illnesses, or other mood disorders.

Seasonal affective disorder is linked to a lack of sunlight. The winter days are shorter, and that itself our circadian rhythm, or internal body clock. Everyone has a specific sensitivity to sunlight, and our bodies take a cue from the morning sunlight each day. In the winter time, the lack of sunlight creates perfect circumstances to experience SAD.

Light therapy, by definition, gives you a healthy supply of what you lack in winter months, often leading to SAD. But light therapy is much more than that. Light therapy’s uses and benefits are many, so while treating SAD, you could also be treating other problems you may not even know of – it’s like killing multiple birds with one stone, and that stone happens to be safe, non-invasive, and non-pharmaceutical.

Light therapy mimics the positive effects produced by exposure to the sun. It reproduces the effects the sun provides us with, and can solve numerous symptoms of SAD through the use of ultraviolet rays. You may be wondering if red light therapy is safe for skin: yes, it is entirely safe. Specifically, with Kayian's light therapy devices, which are FDA-approved and MDA-certified.

With light therapy, you're able to stimulate your cells into rejuvenation. The light works directly at the cellular level and triggers the reproduction of ATP, the fuel our system needs to function properly. 

Light therapy helps with SAD by causing our brain to believe it's getting more sunlight. Even though the light is fabricated, it's still light. We still reap all of the benefits as we do from sun exposure. Melatonin and serotonin are what affects the impact; they too, are triggered by our light therapy devices, which is what battles SAD. 

The scientific evidence on light therapy and SAD says that even within the first hour, you may experience positive results. With daily use of light therapy, thousands of people have overcome the debilitating symptoms of SAD and other disorders, and now even college students can turn to the holistic treatment to replenish the light they’re lacking.

Light Therapy & Kids with Autism

Autism Spectrum Disorder (ASD)

Autism spectrum disorder (ASD) is a complicated syndrome of nervous system development characterized clinically by language impairment, dysfunction in social engagement, language, stereotypical movements and behaviors, and various cognitive deficits.

Light can have a deep influence on people. Different colored lighting can affect our moods, and a lack of natural light can cause depression. This especially applies to those with autism.

Children with autism are especially susceptible to mood changes due to lighting. Lights with mellow colors, like blue, can help a child relax and become creative. Flickering, humming, or harshly colored lights, on the other hand, can confuse and even hurt them. For this reason, it is important that lighting is controllable and monitored in the child’s rooms.

In addition to manufactured lighting, natural lighting also has its effects. Natural lighting has proven benefits for autistic children. Seasonal affective disorder, or SAD, caused by a lack of natural light during winter months, can foster behavioral issues and depression. Natural light has been shown to relieve these symptoms.

Light therapy has been used for more than to relieve these symptoms. Natural light can help regulate a child’s circadian rhythms. These rhythms govern our body’s “internal master clock.” For example, they tell us when it’s time to sleep. A lack of natural light can cause our rhythms to fall out of sync. Therefore, treatment can make a child with insomnia fall asleep without aids and become more alert during the day, among other benefits.

The best time for treatment is in the morning, soon after the child rises. Even spending just 30 minutes in the light can improve their mood and sleeping habits. 30 minutes might not be possible initially, so while building up to it, another session in the afternoon can help. But therapy at night can have negative effects, worsening a child’s routine and making it harder to fall asleep.

Clinical Study

A study examined the efficacy of low-level laser therapy, a form of photobiomodulation, to treat irritability associated with an autistic spectrum disorder in children and adolescents aged 5–17 years. Twenty-one of the 40 participants received eight 5-min procedures administered to the base of the skull and temporal areas across a 4-week period (test, i.e., active treatment participants). All the participants were evaluated with the Aberrant Behavior Checklist (ABC), with the global scale and five subscales (irritability/agitation, lethargy/social withdrawal, stereotypic behavior, hyperactivity/noncompliance, and inappropriate speech), and the Clinical Global Impressions (CGI) Scale including a severity-of-illness scale (CGI-S) and a global improvement/change scale (CGI-C). The evaluation took place at baseline, week 2 (interim), week 4 (endpoint), and week 8 (post-procedure) of the study. The adjusted mean difference in the baseline to study endpoint change in the ABC irritability subscale score between test and placebo participants was -15.17 in favor of the test procedure group. ANCOVA analysis found this difference statistically significant (F = 99.34, p < 0.0001) compared to the baseline ABC irritability subscale score. The study found that low-level laser therapy could be an effective tool for reducing irritability and other symptoms and behaviors associated with the autistic spectrum disorder in children and adolescents, with positive changes maintained and augmented over time.

A significant literature exists on Low-Level Laser Therapy (LLLT) ability, a form of photobiomodulation, to penetrate the skull in both diagnostic and therapeutic applications. Low energy laser passes the skull, and a therapeutic effect likely exists. Low energy laser systems employ the so-called quantum optical induced transparency (QIT)-effect. This effect, electromagnetically induced transparency (EIT), controls optical properties of dense media and can enhance transparency contrast by a factor of five. Therefore, the skull, spine, or joints can be penetrated even with moderate intensity light. Due to the QIT effect, the radiation should reach deep tissue layers in muscles, connective tissue, and even bone, enabling noninvasive transcranial treatments.

Conclusions

The study’s findings strongly illustrate that not only does the application of light therapy affect a sizable, statistically significant, and clinically meaningful improvement in all of the key evaluable behaviors characteristic of autism disorder in children and adolescents, but it continues to affect a progressive and meaningful improvement in symptoms for up to 6 months following completion of the procedure administration protocol.

LLLT can achieve a therapeutic effect by employing non-ionizing light, including lasers, light-emitting diodes, or broadband light in the visible red (600–700 nm) and near-infrared (780–1100 nm) spectra. LLLT is a non-thermal process beginning when a chromophore molecule is exposed to a suitable wavelength of light. Chromophores are responsible for the color associated with biological compounds such as hemoglobin, myoglobin, and cytochromes. When a chromophore absorbs a photon of light, an electron transits to an excited state. The physiologic effects of LLLT occur when photons dissociate the inhibitory signaling molecule, nitric oxide (NO), from cytochrome-C-oxidase, increasing: electron transport, mitochondrial membrane potentials production of mitochondrial products such as ATP, NADH, RNA, and cellular respiration. The leading hypothesis is that the photons dissociate inhibitory nitric oxide from the enzyme, leading to increased electron transport, mitochondrial membrane potential, and ATP production.

References

1. Abbott, A. E., A. C. Linke, A. Nair, A. Jahedi, L. A. Alba, C. L. Keown, I. Fishman, and R. A. Muller. 2018. 'Repetitive behaviors in autism are linked to imbalance of corticostriatal connectivity: a functional connectivity MRI study', Soc Cogn Affect Neurosci, 13: 32-42.
2. Batista-Garcia-Ramo, K., and C. I. Fernandez-Verdecia. 2018. 'What We Know About the Brain Structure-Function Relationship', Behav Sci (Basel), 8.
3. Brown, E. C., M. G. Aman, and S. M. Havercamp. 2002. 'Factor analysis and norms for parent ratings on the Aberrant Behavior Checklist-Community for young people in special education', Res Dev Disabil, 23: 45-60.
4. de Freitas, L. F., and M. R. Hamblin. 2016. 'Proposed Mechanisms of Photobiomodulation or Low-Level Light Therapy', IEEE J Sel Top Quantum Electron, 22.
5. Demirtas-Tatlidede, A., A. M. Vahabzadeh-Hagh, M. Bernabeu, J. M. Tormos, and A. Pascual-Leone. 2012. 'Noninvasive brain stimulation in traumatic brain injury', J Head Trauma Rehabil, 27: 274-92.
6. Emelyanov, A. N., and V. V. Kiryanova. 2015. 'Photomodulation of proliferation and differentiation of stem cells by the visible and infrared light', Photomed Laser Surg, 33: 164-74.
7. Freitas, L. F., M. R. Hamblin, F. Anzengruber, J. R. Perussi, A. O. Ribeiro, V. C. A. Martins, and A. M. G. Plepis. 2017. 'Zinc phthalocyanines attached to gold nanorods for simultaneous hyperthermic and photodynamic therapies against melanoma in vitro', J Photochem Photobiol B, 173: 181-86.
8. Hamblin, M. R. 2018. 'Photobiomodulation for traumatic brain injury and stroke', J Neurosci Res, 96: 731-43.
9. Heiskanen, V., and M. R. Hamblin. 2018. 'Photobiomodulation: lasers vs. light emitting diodes?', Photochem Photobiol Sci, 17: 1003-17.
10. Henderson, T. A., and L. D. Morries. 2015. 'Near-infrared photonic energy penetration: can infrared phototherapy effectively reach the human brain?', Neuropsychiatr Dis Treat, 11: 2191-208.
11. Hiwaki, O., and H. Miyaguchi. 2018. 'Noninvasive measurement of dynamic brain signals using light penetrating the brain', PLoS One, 13: e0192095.
12. Huang, Y. Y., A. Gupta, D. Vecchio, V. J. de Arce, S. F. Huang, W. Xuan, and M. R. Hamblin. 2012. 'Transcranial low level laser (light) therapy for traumatic brain injury', J Biophotonics, 5: 827-37.
13. Jiang, P., V. Vuontela, M. Tokariev, H. Lin, E. T. Aronen, Y. Ma, and S. Carlson. 2018. 'Functional connectivity of intrinsic cognitive networks during resting state and task performance in preadolescent children', PLoS One, 13: e0205690.
14. Kaat, A. J., L. Lecavalier, and M. G. Aman. 2014. 'Validity of the aberrant behavior checklist in children with autism spectrum disorder', J Autism Dev Disord, 44: 1103-16.
15. Karabekiroglu, K., and M. G. Aman. 2009. 'Validity of the aberrant behavior checklist in a clinical sample of toddlers', Child Psychiatry Hum Dev, 40: 99-110.
16. Khuman, J., J. Zhang, J. Park, J. D. Carroll, C. Donahue, and M. J. Whalen. 2012. 'Low-level laser light therapy improves cognitive deficits and inhibits microglial activation after controlled cortical impact in mice', J Neurotrauma, 29: 408-17.
17. Kotkowski, E., L. R. Price, P. Mickle Fox, T. J. Vanasse, and P. T. Fox. 2018. 'The hippocampal network model: A transdiagnostic metaconnectomic approach', Neuroimage Clin, 18: 115-29.
18. Lapchak, P. A., and P. D. Boitano. 2016. 'Transcranial Near-Infrared Laser Therapy for Stroke: How to Recover from Futility in the NEST-3 Clinical Trial', Acta Neurochir Suppl, 121: 7-12.
19. Leisman, G., C. Machado, Y. Machado, and M. Chinchilla-Acosta. 2018. 'Effects of Low-Level Laser Therapy in Autism Spectrum Disorder', Adv Exp Med Biol.
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Light Therapy Used for Ulcerative Colitis & IBD Treatment

Living with any pain is miserable, and inflammatory digestive issues can be one of the most frustrating conditions out there — and it’s widespread, particularly as autoimmunity on the rise.

Inflammatory Bowel Disease (IBD) is a life-long chronic condition of the gastrointestinal tract. Among these conditions, various digestive system parts, including the bowels (intestines), become swollen, inflamed, and ulcerated. This inflammation leads to disruption of the natural processes of digesting food, absorbing nutrition, and healthily eliminating waste.

There are three forms of IBD: Crohn’s disease, Ulcerative colitis, and indeterminate colitis. The main differences between the three are in the areas affected and the depth of inflammation.

Friendly bacteria may cause it, but that doesn’t make it friendly one bit — ulcerative colitis is rather uncomfortable even if the symptoms are often mild. This condition happens when the immune system mistakes our bacteria, which aids in digestion as friendly, leading to the colon and rectum's inflammation.

The main symptoms of IBD are recurring diarrhea, which may contain blood, mucus, stomach, and abdominal pain, and needing to empty your bowels frequently. It is also possible to experience extreme tiredness (fatigue) and loss of appetite, leading to weight loss.

The severity of the symptoms varies, depending on how much of the rectum and colon is inflamed and how severe the inflammation is.

In 2015, an estimated 1.3% of US adults (3 million) reported being diagnosed with IBD (either Crohn’s disease or ulcerative colitis). This was a large increase from 1999 (0.9% or 2 million adults). In the latest years, autoimmune diseases have risen, including stress, diet, lack of exercise, insufficient sleep, and smoking. In general, people haven’t been leading healthy lifestyles, which results in a higher chance of developing an autoimmune disease. While there are ways to treat autoimmune diseases, they typically are conditions that stick with you as long as they can.

The number of ulcerative colitis cases was 40% higher, and Crohn’s disease was 80% higher in northern Europe than southern Europe. This gives more evidence to the theory of vitamin D deficiency coming from lack of light. In France, a study described a transparent north-south gradient for the incidence of Crohn’s disease, but not colitis.

Light therapy can help with a wide range of problems, autoimmune diseases being one of them. For different autoimmune conditions, incidences increase at ranges between 3% and 9% year on year. This includes a 7.0% increase per year of rheumatic diseases such as rheumatoid arthritis. 6.3% increase of endocrinological conditions such as type 1 diabetes.

This is where light therapy comes in as a form of non-invasive therapy. Aside from being non-invasive, it’s an excellent option for those seeking non-pharmaceutical treatment.

The Health benefits of led light therapy are many, and that’s because of how it works. In its essence, light therapy works directly on our cells. Light deposits into our skin cells, penetrating each cell in the targeted area. Then by activation of ATP, reproduction is accelerated, and cellular rejuvenation occurs throughout the whole body.

Use of light therapy at home is available simply by purchasing your own device, using it in the comfort of your own home. How does light therapy help with IBD and ulcerative colitis? Well, light therapy first and foremost helps with tissue repair. Again, through the process of cell rejuvenation and reproduction, our tissue gets the opportunity of healing as well.

By default, UV light is highly anti-microbial, which means it prevents the spread of microorganisms, which infiltrates and causes infection and inflammation. Making an adequate UV light means having the perfect wavelength, which isn’t corrupting to the genetic material and will penetrate and effectively work on the colon.

To alleviate autoimmune symptoms, red light therapy is the perfect non-invasive solution. By healing the body from the inside out, those suffering from autoimmune diseases can finally progress in the right direction. Kaiyan’s light therapy devices are MDA-certified and FDA-approved and perfect at-home treatments for people suffering from these conditions.

Light Therapy's Market Outlook Through 2026

Light therapy has been around for decades, and in the latest few, it’s been gaining momentum and the deserved acceptance from the medical community. The global light therapy market is booming, assumed to reach $1 billion by 2025. 

Some wonder about red light therapy's effectiveness and safety, but companies like Kayian receive FDA and MDA-certification to ensure consumers safety. Light therapy's medical benefits are extensive and range from aesthetics to deep full-body healing. Its countless benefits are why many are looking into this market for its wide range of possibilities. 

Being that it is a non-invasive and non-pharmaceutical form of therapy, light therapy has been challenged through the decades by the pharmaceutical industry. However, as you’re about to see, it’s clear that light therapy is making a breakthrough.

Light therapy's market was valued at over $1 billion in 2020 and is predicted to witness 5.1% CAGR from 2021 to 2027.

Rising incidences of skin-related disorders and growing awareness about care are the factors driving the sunshine therapy market growth.

North America dominated the worldwide light therapy market in 2018. The rise in the prevalence of skin disorders, including eczema and carcinoma in North America, drives the light therapy market. According to current studies by National Psoriasis Foundation, U.S., quite 8 million Americans have psoriasis. 

As per the American Academy of Dermatology (AAD), acne is the most common skin condition within the U.S., affecting up to 50 million Americans annually. An increase in investments from the government and various organizations is predicted to drive the light therapy market in North America.

There are many different product types within the light therapy market, but two main ones are infrared lamps and cold laser therapy. The difference is in the wavelengths. Both have a proven effect on ATP; the real differences preference since the benefits are mainly the same, albeit to a different degree. 

There are also light boxes, floor and desk lamps, light visors, HDST, dawn simulators, light therapy bulbs.

Handheld devices for skin (HDST) are projected to witness 5.6% growth rate till 2027. The light therapy market is estimated to attain a CAGR of 5.8% till 2027, accelerated by the increasing number of sleep disorders coupled with the growing use of light therapy to treat sleeping disorders.

Light therapy's main clinical applications are in biological time sleep disorders, dementia, mood disorders, and insomnia. With light therapy, 5000 lux/h administered daily over several weeks is common. Effects are long-term only if the therapy sessions are persistent and continuous.  

Light therapy is used in many areas of expertise but mainly in hospitals, surgical centers, and diagnostic centers. You can get treatment in a light therapy box perspired from a doctor. 

Some of the eminent players operating within the light therapy market are Beurer, Koninklijke Philips, Aura Daylight, Biophotas, Lucimed, Zepter International, Verilux, and Northern Light Technologies. 

The North American light therapy market size crossed USD 350 million in 2020 due to technological advancements, including growing light therapy applications. Moreover, the presence of major market players and merchandise availability will strengthen the regional market revenue growth.

The market is relied upon to predict vigorous development from constant mechanical headways. Symptoms and side effects of different procedures and constant advancement in light treatment therapy will move individuals' tendency towards light treatment.

In addition, expanding interest for cutting-edge skin and overall health management treatment, for example, blue light and red-light treatment, will help the market development. Also, the rising selection of non-intrusive treatments for different skin problems like wrinkles, facial redness, skin break out, and rosacea will significantly affect future market income.

The interest in blue light additionally expanded significantly during the COVID-19 pandemic. As indicated by medical care scientists, blue light act's as an antimicrobial against various microorganisms. It inactivates a few infections, including COVID and the basic seasonal infection.

Kaiyan Medical is a part of the booming market and our production of FDA-certified and MDA-certified light therapy devices are perfect for at-home treatments.

Incorporating Meditation into Your Light Therapy Ritual

It is said that stress is the precursor of all sickness. In a modern and increasingly fast society like ours, stress is responsible for many mental and physical health issues. Being stressed has become the norm, and yet we often waste our free time on things we don't even enjoy that much (social media scrolling, anyone)? 

We've all been there. We feel stressed as a result of family or relationship issues, or before a test or daunting event. On top of that, leading a hectic and unbalanced lifestyle doesn't help keep us calm and collected, but it rather intensifies the stress.

Stress is tied to a 36 percent greater risk of developing 41 autoimmune diseases, including rheumatoid arthritis, psoriasis, Crohn's disease, and celiac disease. We've become our own enemies. While we're rushing and running to get everything done, our bodies are developing serious problems, and we're not even noticing. 

Taking fifteen minutes out of your day to focus on yourself, your mind, and your body shouldn't be viewed as a luxury. In the time you spend complaining that it takes time out of your day, you could've paused and done it. So, why not change your narrative and allow yourself a little bit of relief? 

So, it’s time to invest in yourself. Light therapy is not only beneficial for our outer beauty but our inner balance as well. It works inward, directly targeting cells and promoting cellular rejuvenation. And there are many ways to use light therapy; from aiding in skincare problems to using our UV light therapy for wound healing.

The type of light therapy depends on your choice; there are a variety of colors that target different issues. Ranging from red and blue to yellow and purple, they all share the same benefit of light working on accelerating our adenosine triphosphate (ATP). ATP is the fuel of our cells and a better ATP production equates to a better organism in total. 

Light is known to trigger the release of serotonin in our brain. Serotonin is also known as the happy "feel-good" brain chemical. Light therapy is the perfect intervention when feeling down; it's also linked to improving other mental issues. 

It helps alleviate stress and is something that can be done at home with our light therapy devices. Not only are you reaping health and beauty benefits, but also you're promoting balanced brain activity. The beauty of doing the treatments yourself is that you get to choose when to do them and on what terms. Pairing your light therapy treatment with meditation could be the way to go.

Why do we mention meditation? Well, its benefits to the body and mind are infinite, and it can also help with your light therapy treatment. There are many different ways to incorporate meditation into your daily routine.

Meditation is, in general, a practice to achieve greater control of the activities of our mind so that it becomes capable of concentrating on a single thought, on a high concept, without overthinking and becoming still, peaceful. Akin to meditation is contemplation, which means letting the mind rest in its natural state. Therefore, it is a practice aimed at self-realization, which can have a religious, spiritual, philosophical purpose, or improve psychophysical conditions.

Pairing your time for light therapy with meditation will only compel your body even more to enter a state most pure to its well-being. Letting the outside world go and only focusing within while your cells truly are being rejuvenated is an incredible process, and a ritual you can incorporate into your daily or weekly self-care regimen.

We so often struggle to find a real escape when we could obtain one right within our homes. Scheduling light therapy-meditation sessions for yourself daily will give you a mindful time to look forward to. You can benefit both physically and mentally in your health, even now when that seems harder to accomplish each day. 

At Kaiyan, we’re dedicated to improving the body from the inside out. To help you achieve a balanced life, our MDA-certified and FDA-approved light therapy devices are the perfect at-home treatment. 

Wellness Gurus: Who's Turning to Light Therapy for Full-Body Treatment

Light therapy has many benefits, working from the inside, out. It not only helps with our appearance but also internal wellness — because who said beauty's just skin deep? 

Many people find themselves turning to this new form of treatment since it's non-invasive and comes with long-term positive effects — something most people aren't used to hearing. 

While outwardly, the skin smooths out, pores are reduced, wrinkles diminished, and collagen restored. Inwardly, light therapy works directly with our cells, generating an increase of ATP, the energy that fuels us. 

LED Light Therapy uses color wavelengths of visible light, each with specific skin benefits. Due to sun damage, aging, skin disorders, healthy skin cells are compromised and have a more difficult time renewing themselves normally.

But why are wellness gurus going crazy for light therapy? 

Light therapy is not that new; however, it's been gaining popularity due to its benefits, especially in the wellness industry. While everyone is eager to look younger, going under the knife is very invasive. Light therapy is not only effective and easy to use; it's non-invasive. The device needed for light therapy is usually a lamp or light therapy box. 

Is light therapy good for skin? Absolutely. And one of the best things next to the long-term effects is that light therapy can be used as laser light therapy at home. This is the most comfortable way of having the benefits of light therapy. Many celebrities themselves are opting for this route as opposed to invasive treatments.

Light is used as a source of energy, and our skin soaks it up, turning it into ATP (our life fuel). Cells reproducing faster and more efficiently brings the repair and rejuvenation of damaged cells, or, in the case of treating acne, kill bacteria. This stimulates the production of collagen and elastin, boosts circulation, and accelerates tissue repair. You simply lie underneath a light screen during the treatment while the LED light device.

What can light therapy be used for you may be wondering? It isn't only beneficial for your skin; it works directly within our cells, accelerating ATP production. This makes it helpful with overall health, physical and mental. Light exposure has also been linked to being a trigger of serotonin, the way natural light does as well. Not only does it trigger serotonin, but also melatonin, which helps regulate your sleep cycle. 

Luckily, instead of having to go to a doctor for your treatments, you have your own LED light therapy mask or device in the comfort of your home. Allowing wellness gurus and everyday people to enjoy the benefits of red light therapy. 

Light therapy devices work not only the face but as a full body treatment that can help with muscle tension and fascia. Fascia is the connecting tissue that holds every organ, blood vessel, bone, nerve fiber, and muscle in place.

Gwyneth Paltrow even explores on goop.com the many different appealing sides to it. “Light acts as a mild stressor on the body in a dose-dependent manner. We always consider stress to be a bad thing, but at low levels, stress can be good for us. It conditions our tissues and stimulates endogenous protective responses that prime us for either existing or future insult.”

Kourtney Kardashian has taken her LED light therapy mask to the public as well, promoting the device and its benefits. She enjoys both red and blue light treatments, often posting her with her at-home mask. She’s mentioned retinol use alongside the regular treatments, and other skin rejuvenating products. 

But more and more celebrities and wellness gurus are turning to light therapy for a full body treatment. Jessica Alba, alongside celebrities including Emma Stone, Chrissy Teigen, Lena Dunham, Kelly Rowland, and Real Housewives of New York City’s Carole Radziwill, have openly discussed red light therapy treatment. 

Many top skincare and wellness brands are turning to Kaiyan for their red light therapy device production. And though we produce devices that are incredibly effective, our devices are also MDA-certified and FDA-approved, giving you security in knowing your devices not only are effective but are safe. 

All About Fascia and Light Therapy

Fascia is a layer of fibrous tissue – or the connective tissue structure that covers muscles, muscle groups, blood vessels, and nerves, joining some structures while allowing others to slide over each other gently. It’s essentially a band or sheet of connective tissue, mainly collagen, under the skin that attaches, stabilizes, encloses, and separates muscles and other internal organs. We classify it by layer as superficial fascia, deep fascia, visceral or parietal fascia.

And its function is significant in the human body. Fascia is what distributes water equally into our carefully structured skin system. It's mainly made up of collagen and ground substance. So how can fascia be harmful?

In itself, fascia isn’t something bad – in fact, is essential to a healthy body; but if it isn't functioning optimally, things can take an ugly turn. The dysfunction of our fascial system can cause great discomfort and pain. Fascia is ideally supposed to move around as we do, and yet there are many things that cause problems with this tissue. 

When fascia is in a shortened position for prolonged periods due to such a lifestyle and overall poor posture, it will adapt – shortening and tightening. Fascial restrictions can also occur from trauma, infection, inflammation, or surgery. These changes affect our fascia's regular movement, creating tension points in our body, pain, applying pressure to surrounding tissues. Therefore, it causes restriction of movement due to the pain and tightening that occurs. So – how can light therapy help?


Light Therapy for Fascia Treatment

Light therapy consists of exposure to a filtered light with an intensity of up to 10,000 lux emitted by a particular lamp. Through light, it can help with a number of problems and specifically offers great benefits to the skin. 

Light therapy treatment for fascia can be done any time of the day; however, it is best done in the early hours of the morning, with a duration of up to 30 minutes, and must be repeated for long-term effect. 

Next to doing stretches and trying other forms of relaxation methods to release tension, fascia can be treated with light therapy. The skin reacts biochemically to light therapy, directly improving cell functions. ATP, our energy source, increases in production with light therapy treatment, resulting in improved cell rejuvenation. Light therapy benefits are that they reduce the discomfort of pain and inflammation by increasing blood flow and tissue repair mechanisms in the body.

Apart from a healthy functioning body, keeping your fascia rejuvenated also helps with appearance. Body symmetry and alignment improve, the blood flow increases, which gives faster exercise recovery, stretch marks and cellulite get reduced, scar tissue breaks down easier, and overall less pain and better performance in the day-to-day tasks. 

Repairing connective tissue such as fascia helps with muscle recovery, which is why light therapy is also used in sports. In the release of ATP, our muscles gain their power back. With light therapy, the recovery is sped up; sessions improve the time it usually takes for our cells to do it themselves. 

Plantar fasciitis is often created from strain at the ligament of the sole of the foot. It's a pain in our heels, and with light therapy, tissue repair is accelerated. Light therapy is an overall regenerating way of treating any issue related to connective tissues. 

Light therapy can also help with cellulite. In itself, cellulite isn't a health issue, but since light therapy helps collagen production, in the same way it helps fascia, it can also be effective with cellulite. With higher collagen levels, skin appears smoother and tightens, which can reduce the appearance of cellulite. 

Light therapy, while treating fascia, can also treat other issues. There are different ways to use light therapy and different settings for different outcomes. Infrared light is used for tissue repair, pain reduction, and similar problems. Red light resolves problems such as inflammation, tissue repair at the surface level, general pain relief as well. Blue light is ideal for combating bacterial issues that lead to our skin becoming acne-prone even when we're past that stage. 

That said, you want to make sure you are using the right red light device. At Kaiyan Medical, we have MDA-certified and FDA-approved laser light therapy devices that will make sure you’re receiving medical-grade light therapy treatment for your fascia and other issues. 

Follow the Numbers: Light Therapy's Projected Market Revenue Surges

Follow the numbers: light therapy's projected market revenue surges

Light therapy is used for many problems, such as skin conditions, eczema, vitiligo, acne, and rosacea. But it's also very popular as a skincare remedy for wrinkles, age spots, and collagen production.  While helping outwardly, it also works directly with mitochondria, the cells' powerhouse, improving our cell production and increasing cellular function. The non-invasive treatment is gaining popularity for its incredible benefits and cost-effectiveness. 

Light therapy also helps with our lack of vitamin D, and with the current world situation of quarantine and COVID-19, the lack has been more than evident. It helps with psychological conditions that have been rapidly increasing in the past few years, and the current situation only aids in the battle against winter blues and depression. This form of therapy increases melatonin levels and mood levels, helping with fatigue and sleep quality.

Since the market has been affected due to the pandemic, people have been turning to light therapy for its mental and physical benefits. The light therapy market is anticipated to reach 1,112.16 million dollars at a CAGR of 5.1%  by 2025, says Market Research Future (MRFR).

The American market is set to take the lead over in the next few years. Growing international curiosity for light therapy will also help the infrastructure, improve quality with more developers, stimulating substantial market growth. 

For winter blues, light therapy should experience a rise in growth by 5.1% till 2027. Due to less sunlight, light therapy proves as the ultimate fit for those in the Northern Hemisphere. The Asia Pacific light therapy market revenue surpassed USD 175 million in 2018, it is poised to expand at 5.7% CAGR through 2027. Their awareness of the growing patient pool and beauty conscious people fuel the demand for light therapy because of its amazing results in various skin conditions. 

Rising per capita income and the growing influence of social media are opening new avenues for the Asian Pacific market. The demand for light therapy is considerable among people in China and Japan. In addition, its popularity is also rising in developing nations owing to its advanced features and low cost. 

A segment of light therapy specializing in floor and desk lamps of the market was valued at more than 140 million dollars in 2018 and will witness a similar growth trend in the future. Similarly, large reflectors in the floor and desk lamps that diffuse bright light for accurate visualization are predicted to be in higher demand in the upcoming years.

Homecare settings portion had its share of revenue, counting more than 490 million dollars in 2018, and will exhibit a similar rising forecast in the upcoming timeline for light therapy. In 2020 these products held up to 60% of the market share. 

Demand for simplicity and more availability is what allows the rising demand for homecare handheld and user-friendly devices. It's predicted to grow gradually. Manufacturers will focus on developing light therapy devices that specifically solve health-related issues at home by providing easy access and improved patient management. 

North America light therapy market size crossed 350 million dollars in 2020 due to technological advancements paired with light therapy's growing use of light therapy.

Key developers in the U.S. have gained approvals from the FDA for new products, like Kaiyan Medical. With FDA-certified and MDA-approved devices, Kaiyan leads the light therapy devices industry and will continue to play a crucial role for the overall growth in the North American industry.


The Perfect Pair: Light Therapy & PRP

Platelet-Rich Plasma (PRP) Injections

In recent years, doctors have learned that the body has the ability to heal itself. Platelet-rich plasma therapy is a form of regenerative medicine that can harness those abilities and amplify the natural growth factors your body uses to heal tissue.

What is Plasma, and what are Platelets?

Plasma is the liquid portion of whole blood. It is composed largely of water and proteins, and it provides a medium for red blood cells, white blood cells, and platelets to circulate through the body. Platelets, also called thrombocytes, are blood cells that cause blood clots and other necessary growth healing functions. Platelet activation plays a key role in the body’s natural healing process.

What is Platelet-Rich Plasma (PRP), and what are PRP injections?

Platelet-rich plasma (PRP) therapy uses injections of a concentration of a patient’s own platelets to accelerate the healing of injured tendons, ligaments, muscles, and joints. In this way, PRP injections use each patient’s own healing system to improve musculoskeletal problems.

PRP injections are prepared by taking anywhere from one to a few tubes of your own blood and running it through a centrifuge to concentrate the platelets. These activated platelets are then injected directly into your injured or diseased body tissue. This releases growth factors that stimulate and increase the number of reparative cells your body produces.

Ultrasound imaging is sometimes used to guide the injection. The photographs below illustrate a PRP injection into a patient’s torn tendon. The ultrasound guidance is shown at the left, and the injection is shown at the right.

PRP harnesses the body’s own rejuvenating powers to stimulate hair growth naturally. The treatment involves drawing a small amount of blood from the patient’s arm. This blood is then spun in a centrifuge until the plasma is separated and growth factors and stem cells are extracted. This plasma, complete with growth factors and stem cells, is then injected into the patient’s scalp, stimulating hair growth.

Light Therapy

Red Light/Blue Light therapy uses light energy to stimulate hair growth. Red light/Blue Light therapy works using light delivered at specific therapeutic wavelengths within infrared and red-light spectrums. The energy from these lights stimulates the hair follicles so that they are constantly in the growth, or anagen, stage. This results in thicker, longer, and healthier hair.

Red light (630 nm) therapy stimulates ATP (cellular energy) production to stimulate hair follicle cells. It also increases blood flow to the hair root, which delivers more nutrients to the hair follicle cells. The increased blood flow is also thought to help flush away the damaging waste products that may affect hair growth.

Near-Infrared light (880 nm) therapy, which is an invisible light energy, promotes collagen and elastin production. It penetrates deeper into the scalp to help reduce inflammation, which causes thinning of hair.

Blue light (420 nm) therapy is especially effective for acne, penetrating molecules within the skin that cause P. acnes bacteria to form. These molecules react

Why Chiropractors Love Light Therapy

Chiropractors Lead the Way

LED light therapy is not new to the medical industry and certainly not new to doctors of chiropractic.

Studied for decades, the use of low-level light therapy (LLLT) — both LED and laser — has been making its way into the medical mainstream in the U.S. since the 1990s. And chiropractors have taken the lead in the clinical use of LED light therapy and are advancing the use of this technology for new applications.

This is no surprise to industry professionals and medical providers because this technology is a perfect pairing to what chiropractors advocate and bring to the medical community: healthy, drug-free healing and pain management options that are highly efficacious. Compared to the high cost and side-effect spectrum of many pharmaceutical drugs, LED light therapy can be a cost-effective alternative to drugs and surgery.

LED light therapy has the ability to increase blood flow and lymphatic circulation, decrease pain, and stimulate many cellular processes that accelerate healing. Plus, it has a high safety level, no known negative side effects is easy to administer, and is non-invasive.

Because LED light therapy can provide pain relief, wound healing and address neuropathy discomfort and various musculoskeletal issues, it is a mainstay in many clinics. Some patients also purchase light therapy systems from their chiropractors for in-home use between office visits for long-term therapy needs such as chronic pain and neuropathy.

It is also an attractive option for new chiropractors just getting started because it can bring substantial benefits to their patients while offering a fast ROI.

How it Works

LEDs deliver wavelengths of incoherent (diffused) light to the body. LEDs are similar to laser diodes, but their light spreads out, unlike the highly focused beam of coherent light that emits from a laser. This more diffused light makes administration exceptionally safe.

This therapy is also known as photobiomodulation — meaning that light can produce a cellular change in the body. Photons of light stimulate the release of nitric oxide, which

is the body’s natural vasodilator, greatly increasing circulation in the local treatment area. Blood flow is increased to nerves and other tissues, improving tissue oxygenation that stimulates healing. This boost persists for several hours after a therapy session.

Research indicates that the benefits of LED light therapy include

  • Increased circulation
  • Decreased inflammation
  • Increased ATP production
  • Collagen production
  • Accelerated exercise recovery time
  • Increased relaxation
  • Decreased stress

LEDs have low power requirements and high efficiency with minimal heat production. Power levels are measured in mW/cm2 (milliwatts per centimeter squared). And LED lifetimes are rated up to 100,000 hours and can last for decades.

The most common device wavelengths are the following:

  • Near-infrared: Many LED therapy devices use the 800 nanometers (nm) range; however, infrared include a much wider spectrum with deep penetration up to 100 mm.
  • Red: 630 to 700 nm, with penetration up to 10 mm.
  • Blue: 405 to 470 nm, with penetration up to 3 mm (beneficial for skin and wound healing).
  • Pulsed frequency(s) or continuous wave devices provide timed sequences of light turning on and off during application, which is thought to accelerate change in the tissues.
  • Continuous-wave devices are always on; no frequency is added to the light.
Applications for Use

Light therapy is commonly used to treat acute and chronic joint pain in the neck, back, leg, shoulder, wrist, knee, and ankle. It can be helpful for arthritis pain, bruises, carpal tunnel syndrome, and musculoskeletal conditions. It is also used to treat skin conditions such as pressure ulcers, wound healing, and scar tissue reduction.

Even NASA has good things to say about light therapy. NASA issued a news release in December 2000, which stated that doctors at Navy Special Warfare Command centers in Norfolk, Virginia, and San Diego reported a 40 percent improvement in patients who had musculoskeletal training injuries treated with light-emitting diodes.1

There are distinct advantages to using LED therapy devices in your clinical practice. For example, Patients can be left unattended during therapy, maximizing staff resources. Large surface areas can be covered by the LED pad or panel, delivering therapeutic photons broadly and safely to the body's targeted area. And systems are generally portable and user friendly.

Moreover, LED light therapy can help you enter niche markets, such as peripheral neuropathy and brain injuries. These are areas where LED light therapy is appearing to be more effective than pharmaceutical approaches.

Brain injuries

An increasing number of scientific studies show expanded indications for LED light therapy to treat neurologic conditions, especially brain injuries and degeneration. The advanced research being done by Michael Hamblin, Ph.D., and his group and by Margaret A. Naeser, Ph.D., at Boston University demonstrates that LED light therapy can positively affect the brain. Naeser’s 2017 study with veterans showed significant improvement after 12 weeks of transcranial photobiomodulation.

Increased function, better sleep, fewer angry outbursts, and less anxiety and wandering were reported with no negative side effects.2

Preliminary brain studies conducted by other groups using transcranial LED light therapy show impressively improved brain blood flow verified before and after single-photon emission computerized tomography (SPECT) brain scans. These brain studies have implications for patients presenting with such conditions as traumatic brain injury (TBI), PTSD, Alzheimer’s, Parkinson’s, concussions, strokes, and depression.

Nearly all neurological disorders have one thing in common: diminished blood flow. And increased circulation and blood flow are precisely what LED light therapy promotes.

Peripheral Neuropathy

More than 3 million new cases of peripheral neuropathy are diagnosed each year in the U.S. alone. LED light therapy has shown significant results in relieving this condition's discomfort and improving sensation, as evidenced by several studies.

Adding LED light therapy systems can help you offer neuropathy therapy as a substantial part of your practice.

FDA Approved

LED light therapy devices have received FDA clearances that temporarily increase local circulation; and the temporary relief of pain, stiffness, and muscle spasms. Many practitioners are hopeful that the FDA will keep expanding clearances for this cutting-edge healing technology.

References
NASA/Marshall Space Flight Center. “NASA Space Technology Shines Light On Healing.” ScienceDaily. http://www.sciencedaily.com/ releases/2000/12/001219195848.htm. Published Dec. 2000. Accessed Jan. 2018.

Salmarche AE, Naeser MA, Ho KF, Hamblin MR, Lim L. Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation:

Case Series Report. Photomed Laser Surg. 2017;5(8):432–441.

Fallah A, Mirzaei A, Gutknecht N, Demneh AS. Clinical effectiveness of low-level

laser treatment on peripheral somatosen- sory neuropathy. Lasers Med Sci. 2017 Apr;32(3):721–728.

Mandelbaum-Livnat MM, Almog M, Nissan M, Loeb E, Shapira Y, Rochkind

Photobiomodulation Triple Treatment in Peripheral Nerve Injury: Nerve and Muscle Response. Photomed Laser Surg. 2016;34(12):638–645.



Clinical Trials for Medical Devices: FDA and the IDE Process

What is a Medical Device?

Section 201(h) of the Food, Drugs, and Cosmetics Act defines a medical device as any healthcare product that does not achieve its principal intended purposes by chemical action or metabolized.

Medical Device Classes
  • Class I — General Controls — Most exempt from premarket submission.
  • Class II — Special Controls — Premarket Notification [510(k)].
  • Class III — Premarket Approval — Require Premarket Application [PMA].
510(k) Premarket Notification
  • Substantial equivalence.
  • 10–15% require clinical data.
  • Performance testing.
  • Usually confirmatory.
  • Type of study dictated by
  • The ability of bench and animal testing to answer questions.
  • Amount of difference between subject device and predicate.
PMA Premarket Approval Application
  • Establish reasonable assurance of safety and effectiveness.
  • Bench-Animal-Human.
  • Clinical Studies.
  • Feasibility and pivotal.
Stages of Review for PMA Device
  1. Pre-Sub: Discuss the device design, bench/animal testing, and the clinical trial
  2. IDE: Request approval for a clinical trial.
  3. PMA: Request market approval.
  4. PMA-S: Request approval for device change or upgrade.

What is an Investigational Device Exemption (IDE)?

The FDA approval of an IDE is required for US human study of a significant risk device that is not approved for the study's indication.

Device trials are unique.

  • Trials tend to be smaller than drug trials.
  • Some novel, many “me-too.”
  • Many difficult to blind, randomize, and control.
  • Many depend on physician technique.
  • Device modifications occur during the trial.
  • Endpoints are highly diverse.
  • Typically, a single pivotal trial follows the feasibility stage(s).
  • Designed to support a “reasonable assurance of safety and effectiveness” for the marketing application.

Types of IDEs

Feasibility Study
  • May provide support for a future pivotal study or may be used to answer basic research questions.
  • Not intended to be the primary support for a marketing application.
  • Endpoints and sample size are generally not statistically driven.
  • Often required by the FDA before the pivotal study to assess basic safety and potential for effectiveness.
  • Generally ~10–40 patients but may be larger.
  • The FDA review is primarily focused on safety and whether the data's potential benefit or value justifies the risk.
Pivotal Study
  • Designed to demonstrate a “reasonable assurance of safety and effectiveness. ness.”
  • Generally intended as the primary clinical support for a marketing application.
  • Endpoints and sample size are statistically driven.
  • Designed to assess both safety and effectiveness.
  • FDA review is much more complex.

Basic Submission Elements

Background of medical issue, the study goals, and why this study will further the science.

A Detailed Description of the Device Understudy
  • Previous studies (preclinical and clinical).
  • Summary of available data.
  • Why is a clinical study needed at this stage?
  • What evidence supports this study/device's safety and the study data's potential to be meaningful?
  • Are there outstanding safety questions that should be addressed with preclinical data?
Risk analysis

Should include:

  • What are the potential risks to the patient?
  • Does the study mitigate the risks where possible?
  • Are the risks outweighed by the potential for benefit and/or value of the study?
  • Patient monitoring and follow-up plan.
  • Inclusion and exclusion criteria.
  • Informed consent document.
  • Sample size and the number of investigational centers, with justification.

Submission Elements, Pivotal IDEs

Primary and Secondary Endpoints

Discussion of the appropriateness of endpoint parameters, hypotheses, and success criteria

Basic Trial Design
  • Controlled? If not, why not?
  •   Randomized? If not, why not?
  •   Blinded? If not, why not?
Trial Conduct and Study Monitoring
  • Sponsor blinding
  • Data handling and adjudication process
  • Independent committees
  • Case report forms
  • Is the right information being gathered to support the study endpoints, and are investigators adequately prompted to report adverse events?

Primary Endpoint Design

Should evaluate the safety and effectiveness of the device in the population expected to be indicated.

  • Generally divided into 1 or more “safety” endpoints and 1 or more “effectiveness” endpoints.
  • A study will be considered successful if both the safety and effectiveness endpoints are met.
  • The clinical protocol should clearly and prospectively detail: — Methods for obtaining endpoint data — Definitions for what will be counted as a primary event in the analysis — Situations in which patient data will be excluded — How missing data will be handled — How the impact of covariates will be assessed.

Sample Size & Follow-Up

Driven by either:

  • Primary safety endpoint
  • Primary effectiveness endpoint

The minimum number of patients and/or minimum duration of follow-up may be required depending on:

  • Understanding of the device's safety and effectiveness  
  • concerns regarding the durability of device safety or effectiveness.

Secondary Endpoints

Generally used to evaluate additional meaningful claims.

  • Generally only considered if primary endpoints are successful.
  • It should be used to provide further insight into the device's effects and mechanisms of action.
  • Definitions and analysis methods should be clearly detailed prospectively.
  • Not considered “statistically significant” unless a pre-specified alpha allocation plan is in the protocol, even if the p-value is < 0.05.

FDA’s IDE Review Decisions

  1. Approval — Approves the trial for a specified number of patients and investigational centers.
  2. Approval with Conditions — Allows sponsor to begin the trial if the sponsor agrees to address the conditions (deficiencies) from the conditional approval letter within 45 days.
  3. Disapproval — The trial may not start until the sponsor addresses the letter's deficiencies, submits this information to the FDA, and receives approval.

Conclusions

One size does not fit all for device trials. Pivotal studies should be designed to evaluate whether there is a “reasonable assurance of safety and effectiveness.” PMA approbation is based upon a Benefit-Risk assessment that strongly considers the outcome of primary safety and effectiveness endpoints. Secondary endpoints are generally used to support claims if the primary endpoints are successful. All endpoint analyses and definitions should be clearly pre-specified in the approved clinical protocol.

50% Greater Growth in Muscles with Red Light Therapy

One study randomly divided participants into two separate groups for an 8-week training program. One group received a red light treatment before every training session, while the other group did the same training without the light treatment. They found that the group receiving the light therapy improved muscle growth 50% greater than those with muscle training alone. Pretty amazing, right?

Another randomized, double-blind, placebo-controlled study using red and infrared light on the biceps demonstrated peak and average performance of more than 12% more than the control group. But while this is all very interesting, I’m sure you’re wondering whether Red Light Therapy is worth it and what it can do for YOU. First of all, I’m sure many of you appreciate the science breakdown, but some of you may not be able to follow, so here’s a simple explanation.

Scientists have discovered that our cells show an incredible response to light, but not just any light. Only in the 660–850 nanometer (nm) range which is the so-called red light range. This type of light energy penetrates deep into the skin, muscle, and joint tissue and stimulates ATP production, which you should think of as your body’s way of transporting energy to where it needs to go. More ATP means more efficient energy transfers in layman's terms, which translates to various benefits at a cellular level.

So, by exposing our body to the therapeutic red light, our cells receive this rejuvenating, anti-aging energy boost that enables them to perform every single function at a heightened level and now that you understand the science behind it, let’s a look at the 5 reasons why it might be a good idea for you to invest in this technology.

Increased Energy & Testosterone

Sometimes we feel lethargic and out of energy, like our body is constantly running on empty. Then you spend some time outside on a nice hot summer day, and you all of a sudden feel amazing? It’s because our bodies rely on light as a source of energy, helping our glands to regulate adrenaline, testosterone, metabolism, and several other functions, and it has been shown that Red Light Therapy can increase testosterone production, which in turn can increase overall energy levels and even improve peak muscle performance.

Reduced Muscle Recovery Time

After a challenging workout, your body works around the clock to repair and strengthen torn muscle fibers. We know this. We also know that nutrition plays a huge role in providing the body with the resources it needs for this process. But what most of you don’t know is that specific wavelengths of light play a role in this process. By enhancing mitochondrial function, red light has been proven to produce measurable gains in peak strength and reduced recovery times.

Faster Healing For Joint & Muscle Injuries

Injuries, repetitive motion, or aging, in general, can lead to severe joint pain and tissue damage. But the body’s natural healing response can be greatly accelerated by red and infrared light. Also, relief from pain, faster recovery times, and reduced arthritis symptoms are just a few more of Red Light Therapy's benefits. For bodybuilders, yes, Red Light is also great for reducing Delayed Onset Muscle Soreness or DOMS. After all, it’s a type of muscle tissue injury as well.

Healthier & Younger-Looking Skin

Red Light Therapy can improve skin clarity, tone, and texture, reduce fine lines, wrinkles, and puffy eyes, help fade scars, acne, and stretch marks, even enhance wound healing and circulation, simply by increasing the production of collagen and elastin.

Remember, collagen is a long-chain amino acid and the most abundant protein in the body. It’s responsible for giving skin its elasticity, hair its strength, and connective tissue its ability to hold everything in place. In fact, the collagen protein makes up 30% of the total protein in the body and 70% of the protein in the skin!

Now while collagen is beneficial to the entire body, it’s most noticeably beneficial to the skin. This is because as we age, the epidermic (or outer layer of skin) thins and loses elasticity in a process known as elastosis. As this happens, we tend to show more aging signs and acquire more wrinkles and stretch marks. But by restoring normal cellular function, because red light stimulates collagen production, red light therapy can help keep your skin looking healthier and younger for LONGER.

Stress Relief

You can’t argue that our minds and body are under constant stress because of our busy lives. Well, Red Light Therapy has been proven to calm our physical and mental state by reducing oxidative stress. Now, I cannot personally attest to that, simply because my stress is through the roof, and other times, I get my mind right and relax, but it makes sense. Oxidative stress is not just harmful to our physical health but also our mental state as well.


Amethyst and Light Therapy

Amethyst crystals have an extremely high heat absorption rate, which accounts for this stone's violet color. When a crystal reflects and absorbs energy or has a near-surface layer of the metal, it will “bounce” this energy back into its surroundings. However, only when a crystal is exposed to heat for long enough time actually radiates heat.

If there are no layers, then the crystal must be emitting radiant light. If we were to look into this infrared mystery further, we would find that the amethyst and several other quartz crystals actually contain carbon crystals, which are also coated in a thin layer of silicon.

These carbon crystals will all convert the infrared light that hits them into visible light, and this infrared radiation has a frequency that can be easily absorbed by the quartz coating.

Therefore, it makes perfect sense that amethyst can emit infrared light and that we might find such gemstones in our day-to-day lives.

Amethyst has been used for many purposes by both the ancient Egyptians and Greeks. It was believed by the ancient Egyptians that amethyst can help in raising the body’s temperature and that it will protect you from fiery stones such as quartz.

The ancient Greeks also believed that amethyst’s color has magical powers because of its beautiful purple color. In fact, the ancient Greeks used amethyst to cast spells; if you boil amethyst in water, place it under a flame for some time, and then remove it, an individual who takes the tea will experience magical visions and feelings.

The boiling water causes the amethyst to release its color into the water, and the hot color in the water symbolizes the fire that the tea burns. The use of amethyst in ancient times has been attributed to the belief that it can produce a mind-body connection.

The color blue inside the amethyst helps the gemstone absorb light, making the amethyst one of the best colors for absorbing infrared energy. Ancient people were the first to use gemstone to cure certain diseases. It was used in ancient times to treat epilepsy, eye problems, memory loss, and pain.

One of the benefits of amethyst to the human body is that it increases the amount of vitamin C distributed throughout the body. This helps prevent the onset of colds and flu.

People who wear amethyst jewelry are less likely to contract skin cancer, which is another common disease. Amethyst jewelry is often recommended for those who have a hard time relaxing, who experience high-stress levels, and for women who are pregnant or nursing.

Amethyst Amplifies Heat Energy Into Far Infrared Rays

Amethyst gemstones can absorb heat energy in the far-infrared rays, known as the “white light” spectrum. This absorption of heat energy by amethyst decreases the gemstone's internal pressure, which increases the amount of radiant energy emitted from it. As a result, the gemstone’s translucency, color, cut, and overall appearance is greatly enhanced. Amethyst also has the unique property of being able to refract microwave radiation.

Far infrared rays are beneficial for many scientific experiments. They are essential for scientific imaging as they allow scientists to view microscopic objects and structures under the microscope.

The properties of amethyst make it particularly effective for infrared images of gemstones. For example, amethyst allows the scientist to see minute bubbles and cavities that would otherwise not be visible to the human eye.

Researchers use amethyst in a variety of medical research-related activities, including cancer treatment. Since amethyst also absorbs heat energy, it is used for skin tanning. Another valuable medical application of amethyst is for treating high blood pressure.

High blood pressure causes many health problems, and the reduced pressure brought about by amethyst helps alleviate these problems.

Amethyst Heated With Electric Heating Power and Emits Far Infrared Rays — A Natural Treatment to Boost Energy

Amethyst, better known as the “stars of quartz” or “sperms of quartz,” is one such green mineral that emits far-infrared rays under the spectrum of visible light.

The crystals of amethyst also have a nearly transparent color, though their color can vary from nearly transparent to a slightly translucent pink.

Humans have used amethyst for centuries as a gemstone. Its healing properties are attributed to its ability to cure various physical ailments like headaches, colds, fevers, nausea, stress, insomnia, digestive disorders, eye problems, and vomiting.

Amethyst’s innate ability to cure these ailments, along with its beautiful color, has made it very popular as a gemstone.

In fact, amethyst is one of the most popular gemstones sold in the world. This is perhaps why amethyst is charged with electric heating power and emits far-infrared rays are so highly sought after.

This stone's powerful rays can help the body get rid of various ailments that may have plagued us for many years.

There are several ways to purify your home environment using amethyst. For instance, you can place small pieces of amethyst on dark areas of the floor, such as dark corners of rooms, hallways, and basements.

Another way of using amethyst is to place small pieces of amethyst on top of hot coals.

Amethyst charged with electric heating power and emitted far-infrared rays is an exceptional aid in keeping any home or space fresh, clean, and safe.

Killing Cancer Cells with the Help of Infrared Light

Researchers at NCI’s Center for Cancer Research have found that a technique called near-infrared immunotherapy for treating cancer has the potential to kill cancer cells in record time, essentially destroying them with the flick of a light switch. Scientists were not certain of the underlying mechanisms of this approach. Still, they succeeded in elucidating this technique in detail at the cellular and molecular level, gaining insights that could help scientists further boost the novel treatment's effectiveness. The laboratory and mouse findings, by Hisataka Kobayashi, M.D., Ph.D., Senior Investigator in the Molecular Imaging Program, and colleagues appeared November 6, 2018, in ACS Central Science.

Near-infrared immunology is an emerging technique for treating cancer that is already being studied in clinical trials. It involves identifying a protein called an antibody that recognizes and targets a specific type of cancer cell. The antibody is joined to a compound that’s sensitive to light and then administered to a patient. Within the body, the drug seeks out and attaches to only cancer cells, not healthy ones. Next, doctors apply a beam of infrared light to the cancer site, either externally or directly, using a fiber optic needle, which activates the drug and causes them to die. Research by Dr. Kobayashi and his colleagues reveals new details into how this cell death occurs.

To learn more about this phenomenon's molecular mechanisms, they studied the effects of a near-infrared immunotherapy agent called antibody-IR700 on a plate simulating human cancer cells in a petri dish using sophisticated microscopes. The researchers discovered that exposure to near-infrared light causes the immunotherapy agent to change its form from Y-shaped to globular dramatically. When it is embedded in a cancer cell's cell membrane, this warping causes scratches along the cell's protective casing. Once enough scratches occur, liquid bursts through the cell’s membrane, causing the cell to rupture in less than a minute following exposure to the light.

The researchers also studied this technique in a mouse with multiple tumors, applying different light intensity amounts to each tumor. They found that higher light intensity resulted in more cancer cells being eliminated. In mice, they detected the “leftovers” of the immunotherapy agent in the mouse’s urine just hours after near-infrared light was applied to the cancer site — a strong indication that the cancer cells were killed.

Dr. Kobayashi notes that this technique doesn’t just target cancer cells or boost the immune system to attack cancer cells — it does both. “All the cell’s proteins and even its DNA are exposed to the immune system. The immune system will recognize that [the proteins and DNA are] coming from the dying cell, and then the immune system will react only to the dying cancer cells,” he explains.

Near-infrared immunotherapy could be applied to any cancer if the right antibody is identified and used. In this study, the researchers analyzed the near-infrared immunotherapy agent IR-700, which is about to be tested in phase III clinical trials for head and neck cancer.

Although the concept of near-infrared immunotherapy is compelling, understanding why it works is critical for several reasons. Kobayashi explains, “Based on these new insights, we might be able to design a new, superior IR700 that would be improved in many respects, such as activation wavelength, stability, and cytotoxic efficacy.”

Immunological consequences after NIR

Destroying cancer cells without damaging normal cells nor compromising the host immune system is a significant benefit of NIR-PIT. Additionally, NIR-PIT induces ICD; that is, it initiates host immunity against targeted cancer cells. NIR-PIT-treated cancer cells release death signals, including calreticulin, ATP, and HMGB1, which can activate adjacent immature DCs even in tumor beds. These signals promote the maturation of immature DCs, which engulf cancer-specific antigens that are released from the ruptured tumor cell, and these mature DCs prime and educate naive T cells to become cancer-specific CD8+ T cells. Such newly primed cancer-specific CD8+ T cells proliferate and attack other cancer cells, resulting in an amplified host anti-tumor immune response. This consequential process could convert some non-immunogenic tumors into immunogenic tumors by recognizing massively released neo-antigens.

This anti-tumor immune activation occurs first in the treated tumor site. Eventually, it extends to other cancer sites because immune cells migrate throughout the body, resulting in a systemic immune response. Therefore, although NIR-PIT is a local therapy, the effect of NIR-PIT can be systemic and may affect distant metastatic sites. Indeed, some tumor-bearing mice and cancer patients achieve complete remission after a single therapy of cancer-cell-targeted NIR-PIT.

An important feature of host immune activation induced by NIR-PIT is that this therapy simultaneously activates the immune system against multiple antigens released from ruptured cancer cells. Most current targeted immunotherapies, including cancer vaccines or CAR-T therapies, identify a single target molecule to base the therapy. Having multiple clones of anti-tumor T cells, each responding to unique antigen, results in a more comprehensive response to tumors expressing a broad spectrum of cancer-specific neo-antigens.

NIR-PIT has demonstrated a profound immune response in humans. First-in-human Phase 1 and Phase 2 clinical trials of NIR-PIT with cetuximab–IR700 targeting EGFR in patients with recurrent and advanced head and neck squamous cell cancer were completed in 2016 and late 2017, respectively. Several complete remissions and multiple significant partial remissions were reported in these studies. The results far exceeded those of pre-clinical models in immune-deficient host xenograft models. Once the models were transferred to syngeneic models, a robust immune response was demonstrated. There is considerable evidence that this same response is seen in humans.

Preparing your Skin for Light Therapy

Can I Use Serum With LED Mask?

It is a question that many people have asked — Can I use the serum with LED light therapy?

Our skin is exposed to harsh environmental factors such as sun, wind, cold, and dust daily. These factors tend to attack our immune system causing it to weaken over time.

When this happens, it allows harmful viruses and bacteria to attack our body, leading to acne breakouts and other skin issues such as dark spots and wrinkles. Acne creams are one way of reducing the symptoms associated with this skin condition. However, these can be irritating to your skin, resulting in unwanted side effects such as redness, irritation, and dryness.

The same can also be said for light therapy, which can have its own side effects. Side effects of LED light therapy include itching, burning, and pain. In fact, most users had reported experiencing these side effects when they first started using LED technology. If you were to use any acne medication type, whether prescribed by your doctor or over the counter, the results would depend largely on the person using the medication.

For example, it could take anything from a few days to a few weeks for acne to clear up. Another point to remember is that while certain medications do show better results for some people, they may not work for you at all.

This is because everyone has different skin types, responds differently to treatments, and requires different times to clear away acne completely.

Some people have found success in using LED therapy with a variety of skin creams. However, there is a downside to using this method. LED light therapy does not help remove excess dead skin cells, as some acne medications do. This means that the acne cream will just be left in place and continue to produce side effects for all patients. Besides, side effects can be more severe than a single acne medication dose when used over a long time when used over a long time.

Before you try to use a serum with an LED mask, you should consult with a dermatologist who can advise you on whether or not LED light therapy is right for you. LED light therapy is safe when administered by a certified medical professional. It can be used safely, even if you have sensitive skin, as long as you choose your doctors wisely. Before any treatment is begun, the medical professional will test your skin to determine what type of acne you have. Testing will determine whether your skin is allergic to any light-emitting diodes in the device used.

The last question to answer is, “How effective is Acne treatment with LED Light?” To answer this question, you will need to look at the results you get from the treatment. If you see immediate results after the treatment, it will likely react to the device's light and not the treatment itself.

However, if you don’t see good results after a month of continuous treatment, it is important to determine why the treatment is not working. It may be that you are allergic to any of the ingredients in the product, or it may be that your skin is not receptive to the treatment.

Hydrated Face For LED Mask Results

The serum is good for hydrated face for LED Mask. It can hydrate the skin by absorbing moisture, providing a slight lift to the skin, and removing any oil or makeup that you are using. The serum also contains vitamins and antioxidants that will help fight against free radicals in your body. Free radicals are harmful agents that have been linked with causing cancer.

By fighting against these harmful agents, Serum is good for hydrated face for LED Mask. People who have used Serum have claimed that the hydrated face and LED Mask work very well together. I have also used Serum on my skin, and I must say that the results were really amazing. In fact, I would go on to say that Serum is so good for hydrated face for LED Mask that I will be using it every single night before bed.

If you don’t have much experience making skin look hydrated, this is the forum for you. Let us first examine the ingredient list of Serum.

This product's main ingredients are Hyaluronic Acid, Vitamin C, Retinol A, Alpha Hydroxy Acids, Vitamin E, DMAE, Peptides, and Glycerin, Ferulic Acid, Aloe Vera.

  • AHA kills the bacteria causing acne and helps to get rid of blackheads.
  • Sodium Laureth Sulfate helps in cleaning the skin by getting rid of dead skin cells and excess oil.
  • Salicylic Acid gets rid of pimples and acne scars, and Glycolic Acid is good in treating acne scars.

All of these ingredients are perfectly good for your hydrated face for LED Mask.

  • Now let us move on to how does Serum works to get rid of the facial puffiness.
  • When you are applying Serum on your hydrated face for LED Mask, you are putting on a layer of serum to the surface of your face.
  • As the serum gets applied, it works its way down into your skin and starts working as a moisturizer.
  • This is why this particular product is top-rated as it works as a good moisturizer without over-drying the skin.
How to Prepare Your Skin For a Red Light Therapy Session?

There are different methods used to prepare your skin, but essentially they all work in the same way: removing all the oil and dirt from the skin and then cleaning it. When I talk about cleansing, I’m talking about daily skincare maintenance products. If you want to know how to prepare your skin for a red light therapy session, this is the part that you need to read.

Most people have no idea how their skin looks like, so when they go into the doctor’s office and they've asked if they’ve had a photodynamic therapy or a laser treatment, they’re not aware of what treatment they might have received.

  • The skin absorbs red light from the sun, and in return, it produces negative ions.
  • These are similar to the particles produced by an activated oxygen generator (you know those things at the gym).
  • During photodynamic therapy, the skin cells absorb the energy from the lasers' red light, which causes the release of more negative ions, which then penetrate deeper into the skin.
  • They’re working like the “batteries” on your car — they give the batteries extra power and allow the car to run much longer.
  • If you want to learn how to prepare your skin for a red light therapy session, you must remove all the grime from your face and neck before the session.
  • Cleansing is one of the most important steps to remember in preparation.
How to Prepare Your Skin for Red Light Therapy Session by Using Non-Dry Cleanser

You might need more than just a good cleanser when trying to prepare your skin for red light therapy. Your cleanser is your friend when you are trying to remove all the dirt and excess oil from your face, but what if your cleanser is too harsh on your skin? If you have dry skin, using a cleanser containing too harsh ingredients may cause dryness, making it harder for you to remove those excess oils from your face.

When you prepare your skin for red light therapy session using the non-drying cleanser, make sure that you would be using a toner with antioxidants and anti-inflammatory ingredients to increase the collagen level the skin.

This will help keep your skin healthy and younger-looking.

Caution: Lotion and Moisturizers For LED Masks Are Not Recommended

The use of moisturizers and lotions is not recommended for LED masks because it will damage your skin. There are also cases wherein people who used such products ended up suffering from adverse effects.

The ingredients in these products may be too strong for the skin to be able to absorb.

You can prevent this by using only non-comedogenic lotions and moisturizers for LED masks.

  • This way, the product is less likely to irritate your skin. In addition to that, you can also use other types of products designed for sensitive or dry skins to use on your face during the event's preparation.
  • However, there are cases wherein people who have been using such moisturizers and lotions as part of their LED facial make-up mask ended up suffering from adverse effects.
  • In these cases, the products were not properly applied to the skin, and the amount that was applied was also insufficient.
  • Because the skin did not get sufficient moisture, the cells underneath the skin's surface could not repair themselves properly.
  • This will result in damaged skin, which will cause more breakouts than before.

Aside from lotion and moisturizers, it would help if you also stayed away from mineral oil, alcohol, and preservatives. These ingredients are not good for your skin, as they can cause dryness and irritation. It would help if you also stayed away from using creams and lotions with fragrance, which can only irritate your skin even more. Instead, look for serums.

If you want to have a glowing complexion without enduring any adverse effects, use a good quality face serum.

Prepare Your Skin For Red Light Therapy by Removing Sunscreen

You probably have heard that it is unsafe to use the sun’s UV rays at home, especially if you use a tanning lotion or a self-tanning lotion. But did you know that it is also not safe to use self-tanning products like tan accelerators and sunless tanning pills to prepare your skin for red light therapy sessions?

This defeats the purpose of using red light therapy, and you must remove sunscreen so that your face and skin are completely ready to receive the red light therapy. This is because self-tanning products contain ingredients that can affect the skin in adverse ways and block the beneficial deep penetrating infrared wavelength from 650nm to 850nm.

How to Prepare Your Skin For Red Light Therapy by Removing Makeup

If you have chosen to have laser acne treatment and you are wondering how to prepare your skin for the red light therapy, you will want to take a moment to learn how red light therapy works before getting started.

Before your session begins, you will be given a short amount of time to get ready for the procedure. This is because your skin needs to be very clean and free of any makeup. Your skin needs to be completely dry before the procedure can begin.

If there is any moisturizer on your skin when you arrive for your appointment, you will have to remove it before your treatment.

Your doctor will ask you several questions about your skin during your appointment, including what type of skin you have and whether or not you have any allergies. During this time, they will also determine if you are a good candidate for the procedure. If you are cleared for the procedure, your skin will be exposed to an intense red light level. This is one of the most effective ways to get rid of acne, and it can also help prevent scars and aging from occurring on your face.

The amount of time that it takes to get your skin prepared for red light therapy varies. In most cases, it is normal to have it take from fifteen to thirty minutes to prepare your skin for the procedure. You may have to remove any makeup at this time as well.

How to Prepare Your Skin For Red Light Therapy by Exfoliating?

When a patient is getting a therapy session done, they will be required to go to the spa or beauty clinic to be given a facial.

A therapist will then start by cleaning the face thoroughly. After the initial cleaning process, the therapist will apply a chemical that will help exfoliate the skin.

This process can irritate the skin, so it is important to prepare your skin before undergoing this procedure. Some common preparations that people use include salicylic acid, alpha hydroxy acid, retinoids, glycolic acid, and other peel-type products.

The exfoliating procedure aims to help the skin cells shed off dead skin cells and replace them with new cells.

This is why it is important to remove all traces of dead skin cells from your face before undergoing the procedure.

It may seem odd at first, but if you want to get the best results from the procedure, you need to gently exfoliate your skin.

Prepare Your Skin For Red Light Therapy With Moisturizers

When you prepare your skin for red light therapy, you are basically preparing to expose the blue spectrum laser's high intensity and the eventual dry out of the epidermis. The skin must be prepared using a good cream containing Reductase or Salicylic Acid, or by exfoliating the skin using a scrub.

After the procedure, you will need to have topical products applied to your skin to prevent the skin from cracking and peeling. This will also help improve your appearance and prevent future scarring. Removing moisturizers before the therapy can be helpful. This is because the skin’s cells will still be in a dormant state when you receive the treatment; therefore, your skin is not at risk for the dryness associated with moisturizers.

This will also improve your skin's look, especially for those who have undergone this procedure many times. However, you must be youthful if e to remove moisturizers in preparation for the session, as some creams may cause excessive dryness and irritation. Once you are prepared for the session, you can expect the doctor to start the red light therapy by generating a small amount of blue light on your skin's top layer.

The light then travels through the skin, reaching the deepest layers where most of the damage occurs. When the blue light is emitted, it is believed that the cells below the surface of the skin begin to absorb the red light, helping to repair the skin. The increased circulation and nutrient absorption help to rejuvenate your skin, leaving it looking younger and healthier than ever before.


How Light Therapy can Help you Manage Holiday Stress

If there's one thing that many of us experience during the holiday season, it’s stress. As much as it can be a time of joy, there’s a lot of pressures that come along with this time of the year. And now, the holidays come with yet another set of stressors that we're not so unaccustomed to: an ongoing global pandemic. None of us have gone through a holiday season during lockdowns and quarantines, making it stressful and difficult to navigate. 

With many of us unable to see our families, we are potentially having to spend the holidays alone, only seeing our loved ones over Zoom or Skype. It’s an unusual time we’re living in right now and it can bring up various emotions. The chronic stress we’re currently living in can lead to serious health problems, including inflammation, headaches, insomnia, digestion issues, and loss of sexual desire. 

On top of everything, the winter season brings SAD (seasonal affective disorder), resulting in many people suffering from low energy, depression, and appetite changes. So, as you can see, we’re dealing with a lot this holiday season, and it’s evermore important to take care of ourselves. 

Of course, the fact that we're separated from our families is difficult, and sadly, there's not much we can do about it. However, we can help ourselves find mental, emotional, and physical balance during these stressful times, and reduce inflammation stemming from stress in the body.

If you're suffering from inflammation and have experienced pain, heat, swelling, and discomfort, you've probably done some Googling to find the cause. As you know, endless search results point to diet, weight, and exercise, which are all valid causes, but they are not the only ones. But there's one main cause we tend to ignore: stress. 

What happens to us when we’re stressed? When we're stressed, our inflammatory response jumps into action and our body enters allostasis. Allostasis is the process of adapting to acute stress by producing stress-related hormones such as cortisol and adrenaline. In other words, our bodies go into "flight or fight" mode. 

This isn't necessarily unhealthy; this is part of the natural human response. However, the problem comes when we're experiencing chronic stress as our bodies cannot return to homeostasis. This causes the body to believe we're fighting for our lives continually, and ultimately causes inflammation. 

Naturally, in today’s world, you’re going to experience stressful situations. And yes, yoga and meditation help to reduce stress, but they don’t reduce inflammation entirely. So, what can you do? When it comes to bringing your body back to a state of balance, red light therapy works wonders.

If you've ever visited the doctor for inflammation issues, you've probably been prescribed nonsteroidal anti-inflammatory drugs or steroids. Though they're useful, they don't deal with the root cause of your inflammation.

Red light therapy does combat the root of inflammation by sending wavelengths of red and near-infrared (NIR) light to the skin and cells, cutting down the oxidative stress and enhancing cellular energy to boost your immune system, even preventing diseases that are caused by chronic inflammation. In addition, red light therapy also increases the cell's healing process, improving blood flow and reducing any existing inflammation. 

Aside from the inflammation, red light therapy also aids in treating seasonal affective disorder (SAD). Red light therapy’s benefits are particularly powerful during the winter season, as you can eliminate or reduce winter-related conditions such as inflammation and SAD. 

Inflammation is a natural part of the human body, but chronic inflammation can cause serious health risks that can significantly reduce the quality of your life. Therefore, we’re intent on helping people reduce inflammation at Lunas through our state-of-the-art red light therapy devices that are MDA and FDA approved and can be used from the comfort of your home during this holiday season. 

Winter can be a dreary and gloomy time of year, but that doesn’t mean you need to feel poorly, too. With red light therapy, you’ll be able to reduce inflammation, eliminate symptoms and get your life back. 

Light Therapy and Orthopedic Surgery

At some point in most of our lives, we’re all going to encounter a visit with an orthopedic doctor. As a society, we’re constantly straining our muscles, joints, ligaments, and tendons. 

In addition, nutrient deficiencies are incredibly common as more people resort to eating processed and fast food for their meals. With a lack of nutrition, our bones, joints, and muscles do not receive what they need to sustain themselves and remain healthy. 

Conditions such as Osteroporsosis—or bone loss—can create pain, inflammation, and bone breakage. Other nutrition deficiencies can cause low immunity, muscle weakness, and joint issues. 

Of course, nutritional deficiency isn’t the only reason someone can suffer from joint, muscle, tendon, or ligament issues. Aside from doing repetitive movements, athletes are more prone to muscle, tendon, ligament, and joint injuries. 

Whatever the cause may be, there’s one thing they all have in common: people with these types of injuries often need to be seen by an orthopedic surgeon. 

For some people, physical therapy can help; however, more people have to undergo orthopedic surgeries. Today, the most common orthopedic surgeries are ACL reconstruction, knee, hip, and shoulder replacements. If there’s one thing everyone who’s experienced orthopedic surgery can say, it’s that recovery can be extremely challenging and lengthy. 

Sadly, there’s not much one can do when recovering from orthopedic surgery. You simply have to wait until the operated area heals naturally. But, there is one specific treatment that aids the post-recovery period and prevents future joint issues. What is it? It’s red light therapy, of course! 

Red light therapy works by enhancing energy within your body’s cells, which works to repair any damaged cells in the body. By repairing damaged cells in the body, it reduces pain and inflammation, increasing the recovery period. 

Red light therapy has proven to achieve a few things:

  • It stimulates cells to remove toxins
  • Increases oxygen flow to the cells
  • Blocks pain signals in the brain and releases endorphins and enkephalin (a natural pain killer in the body)
  • Jumpstarts the body’s healing process by stimulating the mitochondria in the cells.

That said, red light therapy can be used to treat a wide range of joint, muscle, tendon, ligament, and bone injuries. The reason why it works on a wide scale of injuries is due to the fact it can treat various tissues within the body, reducing inflammation and pain. 

A review by Harvard Medical School and the University of Sydney found that laser therapy can be effective for treating:


  • Post-surgical pain
  • Tendonitis
  • Muscular back pain
  • Carpal tunnel syndrome
  • Cervical or lumbar radiculopathy
  • Epicondylitis
  • Osteoarthritis and rheumatoid arthritis
  • Whiplash injury
  • Frozen shoulder
  • Tendinopathy
  • Fibromyalgia
  • Sprains and strains

Red light therapy is also highly used within the athletic community to speed up the healing process, help players get back on the field, and prevent future injuries. 

Through red light therapy, it prevents muscle soreness, fatigue, and aids in recovery. By having the muscles recover quickly, red light therapy reduces inflammation, allowing the muscle to heal and avert future injuries.

From mild to severe joint, muscle, ligaments, bone, and tendon conditions, red light therapy improves recovery time and aids the healing process. The beauty is that this therapy is entirely possible to undergo from the comfort of your own home.
Lunas red light therapy devices provide high-quality at-home treatments to help you make the most out of your recovery. With red light therapy, not only will you recover from surgery, but you’ll feel even better than before.

Can Red Light Help Supplement a Keto Weight-loss Diet?

Weight loss is something that many people struggle with, and our modern day lifestyles can make it challenging to prioritize healthy eating and movement. We’re living fast lives, often resorting to highly-processed foods, and skipping out on exercising, all of which are the main contributors to weight gain. 

In 2020, the obesity rate in the U.S. was 42.4%. Though it’s often overlooked, people with a high BMI are at very high risk for cardiovascular diseases, hormonal issues, diabetes, cancer, and musculoskeletal disorders. 

However, in recent years, there’s been a shift in people’s mentalities. Yes, many are still opting for meal replacements and weight loss surgeries; however, others are focusing on eating clean and eliminating preservatives from their diet. Instead of doing quick diet fads, many are trying to change their lifestyle, even turning to alternative eating methods such as the ketogenic diet – a low-carb, high- fat diet that shares similarities to the Atkins diet. Essentially, you eat fewer carbs and replace them with fat. By doing this, the body goes into a state of ketosis, enabling the fat from your diet and body to be burned into energy. 

However, the keto diet does more than just help people lose weight. It reduces blood sugar and insulin levels, sleep disorders, seizures, and other brain disorders. It’s clear that the keto diet does have health benefits aside from weight loss. This diet alone has changed the lives of millions of people around the world. But wait...what does this all have to do with red light therapy? 

Before we talk about red light therapy working alongside keto, it’s crucial to understand the importance of natural light to the human body. Our bodies respond to light the same way it does to carbs, proteins, and fats. Our bodies are built to function with an optimal amount of natural light so that our cells can produce energy

We need light like we need fruits and vegetables. Similar to when we eat junk food, if we’re exposed to an abundance of artificial light, our bodies don’t function optimally. However, we’re spending more time inside than ever, meaning we’re not getting enough natural light. Simply put: it isn’t good for our bodies and minds.

So how do the two work together? If you’re on the keto diet, your body will go into a state of ketosis, which promotes increased weight loss, specifically in the abdominal area. When the body is able to burn fat efficiently, the body works better—this the same goes for red light therapy. 

Red light therapy strengthens the mitochondria inside our cells. The mitochondria are the powerhouse of the cells where energy is created. By improving the function of the mitochondria, a cell produces more ATP (adenosine triphosphate). With an increase in energy, the cells function optimally and are able to regenerate at a faster pace. 

Keto and red light therapy work to naturally enhance our body’s functionality as both operate to enhance the mitochondria. Keto works to burn fatty acids and ketones instead of glucose. With red light therapy, it decreases oxidative stress that slows energy systems. When using red light therapy during a keto diet, your cells are able to work efficiently as both increase energy, physical performance, and weight loss

But red light therapy does more than just enhance your body’s energy and physical performance. Red light therapy improves sleeping patterns by adjusting your circadian rhythm and helping the brain produce natural melatonin. Developing a regular sleep pattern on top of losing weight will only help improve your weight loss journey, as well as balance your hormones. Red light therapy also reduces inflammation and joint pain, which helps the overall weight loss experience. 


If you’re on the keto diet or considering giving it a try, consider easing into the process by supplementing with Lunas’ MDA and FDA-approved red light therapy devices to help aid your weight loss journey.

Light Therapy - An Alternative to Botox and Fillers?

It’s safe to say that most people would prefer to slow down the physical signs of aging, particularly on their faces – and the proof is in the numbers. In 2018, the global anti-aging market was estimated to be worth around $50.2 billion U.S. dollars. Now that's a lot of skin cream and Botox. And those numbers are only increasing: by 2027, the anti-aging product industry is projected to be worth $83.2 billion U.S. dollars. 

Of course, a large portion of sales are going to anti-aging creams and serums; however, there's been an increase in soft-tissues cosmetic procedures like Botox and filler treatments. A report from the American Society of Plastic Surgeons from 2018 reported around 7.4 million injections of botulinum toxin (Botox) and 2.6 million dermal filler injections we used that year. 

In America alone, Botox and fillers ranked the second most popular, minimally-invasive cosmetic procedures. But why are they so popular? Due to their invasiveness, they're more effective than anti-aging creams. However, that comes at a potentially risky and painful price. 

Botox's side effects include bruising and swelling at the injection site, fever, chills, and headaches. Some side effects are specific to the area of injection and include drooping eyelids, excessive tearing, and uneven eyebrows and other facial muscles. More importantly, research on the long-term side effects of Botox and fillers is limited. There are immediate results, yes; however, there's an unclear understanding of what Botox and fillers do to the body in the long-term.

Aside from health concerns, Botox and fillers can quickly add up financially, too. The most common Botox and filler treatments cost hundreds of dollars per session. Women and men around the world are risking their health and money to look youthful, but what they don't realize is there's non-invasive alternatives to these procedures, including light therapy. 

Aside from light therapy’s plethora of benefits for the human body, it is an amazing anti-aging alternative for those looking for non-invasive and natural anti-aging results. Light therapy reduces fine lines and wrinkles, but goes beyond just skin deep. 

While Botox and fillers work to cover the symptoms of aging skin, light therapy solves the problem at a cellular level. As we age, our body’s collagen production decreases, leaving our skin less plump and full. However, through light therapy, you’re actually stimulating collagen production beneath the skin to receive natural and similar results to Botox and fillers. 

Light therapy works by delivering wavelengths of red and near-infrared light to our skin and cells. Red light enhances our cellular function, stimulating the cell's mitochondria to produce ATP (adenosine triphosphate) energy. This boost of cell energy promotes collagen and elastin production, bringing the plumpness back into your skin. 

A 2014 study found that users of red light therapy experienced significantly improved skin complexion and increased collagen. Angela Lamb, M.D. and associate professor of the Department of Dermatology at the Icahn School of Medicine at Mount Sinai Hospital in New York City, stated that "Science shows that red light therapy protects existing collagen and boosts new production. Plus, it helps with texture, tone, pore size, and wrinkles."

However, there are more benefits to red light therapy than natural collagen production. Light therapy also aids in diminishing fine lines and wrinkles, reduces scarring, fights acne, treats inflammation, and aids in muscle recovery.

The proof is in the research, and study after study has shown the same results: red light therapy works for anti-aging. Rhonda Klein, M.D., a board-certified dermatologist in Connecticut, said that “Realistically, you can expect RLT to improve your skin’s tone and texture. We know that it soothes inflammation, improves mild acne, and proactively treats fine lines and wrinkles, in addition to other benefits.”

Lunas’ red light therapy devices are both MDA and FDA-approved, assuring you receive the highest quality of red light treatments available on the market, which is essential in receiving the best, most efficacious results.

The Children of Fire - Infrared Light & Fire

The control of fire by early humans was a turning point in the technological evolution of human beings. Fire provided a source of warmth, protection from predators, a way to create more advanced hunting tools, and a method for cooking food. These cultural advances allowed human geographic dispersal, cultural innovations, and changes to diet and behavior. Additionally, creating fire allowed human activity to continue into the evening's dark and colder hours.

Claims for the earliest definitive evidence of fire control by a member of Homo range from 1.7 to 2.0 million years ago. Evidence for the “microscopic traces of wood ash” as the controlled use of fire by Homo erectus, beginning some 1,000,000 years ago, has wide scholarly support. Flint blades burned in fires roughly 300,000 years ago were found near fossils of early but not entirely modern Homo sapiens in Morocco.

The fire was used regularly and systematically by early modern humans to heat treat silcrete stone to increase its flake-ability for toolmaking approximately 164,000 years ago at the South African site of Pinnacle Point.[5] Evidence of widespread control of fire by anatomically modern humans dates to approximately 125,000 years ago.They also used fire for light.

Infrared Light from Fire

The burning of wood (or other organic materials) releases energy in the form of infrared light. When you take a photo of someone with an infrared camera, what do you see? A heat “signature” that correlates (approximately) to their metabolic activity.

What is infrared light? It is a spectrum of light that we can’t see but that powerfully shapes our biology. You sense infrared light as “heat.” The heat you feel from the sun — that’s the sensation of infrared light. The feeling of heat you get when you put your hand close to an oven, toaster, or fire — that is also infrared light. The heat of another person’s body — infrared light again. Hot springs transfer heat to your body in the form of infrared light stored in the water itself. When you take a hot shower or hot bath, the same principle is at work.

Infrared light has been used for decades as a heat source for saunas. Before IR saunas, we had sweat lodges and traditional stone saunas. In traditional saunas and sweat lodges, stones absorb energy from either an electronic heating unit (in the case of a sauna) or a fire. The light is stored in the stones and gradually released during the sweat lodge or the sauna. Both methods use light to heal the human body.

And infrared light doesn’t just transfer “heat” to your body — it turns the water in your cells into batteries. This is likely why ancient cultures recognize the importance of fire, sweat lodges, and saunas, especially in winter.

It is not a coincidence that sitting down next to a fire is so comfortable. Firelight is natural and helps to manage melatonin production as well as keeping our circadian rhythms under control.

A fireplace or fire-pit isn’t just an ornamental detail of your home, and it’s a tool you can use to live a healthier life.

References

  1. James, Steven R. (February 1989). “Hominid Use of Fire in the Lower and Middle Pleistocene: A Review of the Evidence” (PDF). Current Anthropology. 30 (1): 1–26. doi:10.1086/203705. Archived from the original (PDF) on 12 December 2015. Retrieved 4 April 2012.
  2. ^ Luke, Kim. “Evidence That Human Ancestors Used Fire One Million Years Ago.” Retrieved 27 October 2013. An international team led by the University of Toronto and Hebrew University has identified the earliest known evidence of the use of fire by human ancestors. Microscopic traces of wood ash, alongside animal bones and stone tools, were found in a layer dated one million years ago.
  3. ^ Miller, Kenneth (May 2013). “Archaeologists Find Earliest Evidence of Humans Cooking With Fire”. Discover.
  4. ^ Jump up to: a b Zimmer, Carl (7 June 2017). “Oldest Fossils of Homo Sapiens Found in Morocco, Altering History of Our Species”. The New York Times. ISSN 0362–4331. Retrieved 6 July 2017.
  5. ^ Brown, Kyle S.; Marean, Curtis W.; Herries, Andy I.R.; Jacobs, Zenobia; Tribolo, Chantal; Braun, David; Roberts, David L.; Meyer, Michael C.; Bernatchez, J. (14 August 2009), “Fire as an Engineering Tool of Early Modern Humans”, Science, 325 (5942): 859–862, Bibcode:2009Sci…325..859B, doi:10.1126/science.1175028, PMID 19679810, S2CID 43916405

Blue & Red Light for Rosacea

Rosacea is a common inflammatory skin condition affecting approximately 5% of the world population. Therapeutic approaches to rosacea are focused on symptom suppression employing anti-inflammatory agents. Photodynamic therapy, especially light-emitting diodes, has been introduced as a valid alternative to conventional therapy.

Because of rosacea's potential complexity, it has been classified into subtypes according to signs and symptoms that often occur together. Patients may have characteristics of more than one subtype at the same time. Although the cause of rosacea is unknown, several possibilities are currently being studied, including flushing, inflammatory pathways, and Demodex mites. Simultaneously, a growing range of therapies is available to address rosacea's signs and symptoms. While your doctor will tailor medical therapy to your individual case, treatment options may often be keyed to standard subtypes and level of severity.1

As with any medical therapy, outcomes of rosacea treatment may vary from case to case. Compliance with therapy — using your medication as your doctor prescribes — is an important key to success. Please consult a dermatologist or other physician to determine the appropriate therapy for your individual case.

Subtype 1: Facial Redness

Subtype 1 (erythematotelangiectatic) rosacea is characterized by flushing and persistent facial redness. Visible blood vessels may also be present, and facial discomfort is common.

Research into the physical processes involved in rosacea has recently led to new prescription therapy to relieve facial redness. It may also be important for you to identify and avoid lifestyle and environmental factors that trigger flushing or irritating your skin. The most common factors are covered in Rosacea Triggers, and a Rosacea Diary is available to help you identify and avoid those factors that affect your individual case.

The appearance of flushing, redness, and visible blood vessels may also be concealed with cosmetics, and facial discomfort may benefit from appropriate skincare, both discussed under Skin Care & Cosmetics.

Visible blood vessels and severe background redness may be reduced with lasers or intense pulsed light therapy. Several sessions are typically required for satisfactory results, and touch-up sessions may later be needed as the underlying disease process is still present.

In specific cases, extensive flushing may be moderated somewhat through the use of certain drugs.

Subtype 2: Bumps and Pimples

Subtype 2 (papulopustular) rosacea is characterized by persistent facial redness and acne-like bumps and pimples and is often seen after or at the same time as subtype 1. Fortunately, however, several medications have been extensively studied and approved for this common form of rosacea and may also be used on a long-term basis to prevent symptoms recurrence.

In mild to moderate cases, doctors often prescribe oral and topical rosacea therapy to bring the condition under immediate control, followed by long-term use of topical therapy alone to maintain remission. A version of oral therapy with less risk of microbial resistance has also been developed specifically for rosacea and is safe for long-term use.

Higher doses of oral antibiotics may be prescribed, and other drugs may be used for patients who are unresponsive to conventional treatments.

Subtype 3: Skin Thickening

Subtype 3 (phymatous) rosacea is characterized by skin thickening and enlargement, most frequently around the nose. This condition develops primarily in men. Although mild cases may be treated with medications, moderate to severe manifestations, typically require surgery.

A wide range of surgical options is available, including cryosurgery, radiofrequency ablation, electrosurgery tangential excision combined with scissor sculpturing, and skin grafting. A surgical laser may be used as a bloodless scalpel to remove excess tissue and recontour the nose, often followed by dermabrasion.

Subtype 4: Eye Irritation

Subtype 4 (ocular) rosacea is characterized by any one of many eye symptoms, including a watery or bloodshot appearance, foreign body sensation, burning or stinging, dryness, itching, light sensitivity, and blurred vision. A history of having styles is a strong indication and has “dry eye” or blepharitis.

Treatment for mild to moderate ocular rosacea may include artificial tears, oral antibiotics, and the eyelashes' daily cleansing with baby shampoo on a wet washcloth. More severe cases should be examined by an eye specialist, who may prescribe ophthalmic treatments, as potential corneal complications may involve visual acuity loss.

Treatment and Conditions


Currently, there are two traditional treating methods, such as medications and physical treatment. Doctors can prescribe medications. Usually, the medications are antibiotics. The thing is, however, there are side effects from the antibiotics. Additionally, there is no proof that Rosacea is a bacterial condition. So the effectiveness of treatment could remain uncertain. Plus, going to see a doctor can be time-consuming & money consuming.

Physical treatment can be soup or gel to help better improve the skin. However, people have different skin types. Usually, it is super expensive to diagnose the skin condition in great detail; people have different skin types. The wrong usage of beauty products could lead to worsen skin problems or increase sensitivity.

Several therapeutic approaches are currently available for treating rosacea, and they are mainly aimed at controlling disease symptoms. The therapeutic plan has to be adapted to the rosacea subtype and tailored according to the patient's dominant manifestations. In general, the reduction of oral therapy in favor of topical or physical therapy is desirable to reduce side effects for patients and increase the treatment's safety.

The therapeutic approach has blue (480 nm ± 15 nm) and red (650 ± 15 nm) LED light-based therapy in patients affected by rosacea. Previous research reported the efficacy of red and blue light coupled with mild to moderate acne lesions. Blue light (400–470 nm), due to its lower penetration, is useful in such skin conditions related to the skin's epidermis layer; therefore, it can also interfere with human sebocyte proliferation. On the other hand, red light (630 nm) is reported to affect sebum production significantly. The benefits deriving from PDT using LEDs are not limited to its efficacy but are also related to its safety and tolerance by patients; therefore, its advantages can be extended to a broad range of dermatological conditions.

References:

Two AM, Wu W, Gallo RL, Hata TR. Rosacea: part I. Introduction, categorization, histology, pathogenesis, and risk factors. J Am Acad Dermatol. 2015;72(5):749–58. quiz 759–60. PMID: 25890455

Plewig G, Kligman AM. History of Acne and Rosacea. In: ACNE and ROSACEA. Berlin: Springer; 2000.

Odom R, Dahl M, Dover J, Draelos Z, Drake L, Macsai M, Powell F, Thiboutot D, Webster GF, Wilkin J. Standard management options for rosacea, part 2: Options according to subtype. Cutis, 2009;84:97–104.

Kolontaja-Zauber, I., Ināra Ančupāne, Andra Dērveniece, Aija Žileviča, & Ilze Ķikuste. (, 2018). Impact of intense pulsed light therapy on the quality of life of rosacea patients. Proceedings of the Latvian Academy of ences Section B Natural Exact and Applied sciences, 72(1), 9–15.

Kim, B. Y., Moon, H. R., & Ryu, H. J. . (2018). Comparative efficacy of short-pulsed intense pulsed light and pulsed dye laser to treat rosacea. Journal of Cosmetic & Laser Therapy, 1–6.

Bo, Young, Kim, Hye-Rim, Moon, & Hwa, et al. (2018). Comparative efficacy of short-pulsed intense pulsed light and pulsed dye laser to treat rosacea. Journal of Cosmetic & Laser Therapy Official Publication of the European Society for Laser Dermatology.

Smith, J. P. K. . (1984). The eyes have it: young children’s discrimination of age in masked and unmasked facial photographs. Journal of Experimental Child Psychology.


Light Therapy & Diabetes

DAccording to the Centers for Disease Control and Prevention (CDC), more than 100 million adults in the United States suffer from diabetes or pre-diabetes. A chronic disease characterized by elevated blood glucose levels (blood sugar), diabetes develops because the body doesn’t make enough insulin, a hormone produced by the pancreas. Low insulin levels cause glucose to build up in the blood, resulting in various health problems, some severe.

There are three types of diabetes: type 1, type 2, and gestational. Whichever type you may have, light therapy could be the treatment solution you’ve been looking for. This article will explore red light and near-infrared (NIR) light for diabetes: a novel solution that helps treat this disease's complications at the cellular level — healing from the inside out.

Red and Near-Infrared Light for Diabetes

While some people with type 2 diabetes (also called adult-onset diabetes) can achieve target blood sugar levels with lifestyle changes, diabetes medications, or insulin therapy may also be needed to control blood sugar. Many medications cause serious side effects. Diabetes has no cure, and symptom management is the only way to coax the disease into remission.

Red and NIR light has been used successfully to treat the complications associated with diabetes. Before we delve into that, let’s do a quick overview of what this treatment method actually is.

Red light therapy, also called low-level light therapy (LLLT) or photobiomodulation, is an umbrella term referring to the red light and NIR light. It uses powerful light-emitting diode (LED) bulbs to deliver intense beams of red and NIR wavelengths to bare skin.

Wavelengths of light are measured in nanometers (nm). Research has shown that red wavelengths from 630nm to 660nm, and NIR wavelengths from 810nm to 850nm, have the greatest scope of benefits — and come with no side effects.

Although studies often focus on either red or near-infrared wavelengths, experts say the best treatment approach is to use both. Doing so will provide skin-deep as well as deep-tissue benefits. For example, the 630nm to 660nm wavelengths address the skin's health, and the longer 810nm to 850nm NIR wavelengths penetrate deeper into the body. NIR wavelengths can even penetrate bone and hard connective tissue like cartilage.

Increase Capillary Formation for Improved Blood Flow

Thomas Burke, Ph.D., a retired physiologist with the University of Colorado Medical School, has studied blood flow — specifically changes in blood flow — for more than 30 years. Dr. Burke’s extensive research into the effects of red light therapy on circulation has led him to conclude that infrared light increases blood flow in any site in the body to which it is applied. This has profound implications for treating slow-healing wounds such as diabetic foot ulcers, which affect approximately 15 percent of patients with diabetes.

One effect of diabetes is meager amounts of nitric oxide produced by the body, which hinders normal blood flow. This is one reason people with diabetes often develop a circulatory condition called peripheral arterial disease, in which narrowed blood vessels reduce blood flow to the limbs. Many diabetes patients also develop diabetic neuropathy, a peripheral nervous system disorder that causes loss of feeling in the extremities, especially the feet.

The combination of poor blood flow and neuropathy can make people with diabetes more susceptible to ulcers or infections in the feet that, if allowed to spread, may require extreme measures such as amputation. LLLT can help circulation by stimulating the formation of tiny capillaries in areas treated by the light. This allows for better oxygen and nutrient delivery to the body’s peripheral regions, including the feet, which seem to bear the brunt of diabetic complications.

Increased Cellular Metabolism and Energy

The decreased blood flow that’s characteristic of diabetes interferes with the proper functioning of mitochondria, the “energy factories” inside most body cells. When mitochondria function normally, their primary job is to produce adenosine triphosphate (ATP), an energy-rich molecule that serves as fuel for cells. ATP is essential for normal cellular functioning, including repair and replication.

Poor cellular energy, officially known as mitochondrial dysfunction, is one of the main causes of diabetic neuropathy, so restoring normal mitochondrial function is essential. When there’s a chronic blood sugar imbalance, cells become stressed, unable to function properly, and unable to repair themselves.

Low-level light therapy addresses mitochondrial dysfunction by increasing ATP production. This, in turn, energizes cells and sparks a chain reaction of beneficial biological processes and improved health. When mitochondrial function is returned to normal, it supports skin ulcers and neuropathic pain and helps restore normal peripheral nervous system functioning.

Restored Normal Nerve Functioning

Until LLLT was developed, loss of sensation in the feet of diabetics was considered progressive and irreversible. Even today, the recommended treatment is often anti-inflammatory drugs that interrupt pain pathways. These drugs do not address the underlying problem: abnormal nerve signaling due to inflammation and mitochondrial dysfunction.

Today, diabetic neuropathy can be treated using near-infrared light. According to a 2015 study by medical researchers from Iran, NIR light therapy effectively reduces neuropathic pain and promotes damaged nerve cells' regeneration.

An earlier study by researchers from Japan also focused on LLLT’s effects on nerve regeneration. It is known that disrupted blood sugar levels can lead to oxidative stress, which can cause inflammation. The study revealed that NIR light acts as an antioxidant and reduces inflammation, conducive to nerve regeneration.

Increased Collagen Production

Diabetes can cause uncomfortable, often painful changes in the skin, including severe dryness, peeling, cracking, and abnormal callus growth. Red light therapy boosts the body’s natural collagen production so that as skin cells are renewed, the damaged skin can be gradually replaced by healthy skin. Improved blood flow and cellular functioning also support healthy skin growth.

Reduced Inflammation for Faster Wound Healing

Diabetic foot ulcers may form due to a combination of poor circulation, immune system deficiency that makes it hard for the body to fight off infection, diminished foot sensitivity (diabetic neuropathy), and ill-fitting shoes. Infected and dead tissue will need to be removed. The growth of healthy new tissue needs to be supported with blood sugar management and optimal mitochondrial functioning, and collagen production.

A Stronger Immune System

Improving health requires a robust immune system, and LLLT can help in several significant ways. For instance, it stimulates the production of stem cells, which are the body’s master cells with the potential to develop into many different types of cells. Stem cells remain in a dormant, non-specialized state until they are needed, when they are mobilized into action and carried to various parts of the body where they take on specialized roles.

Also essential for a healthy immune system is the thyroid, which LLLT helps to balance. People with diabetes have an increased risk of developing hypothyroidism, which is an underactive thyroid. Hypothyroidism results in mitochondrial dysfunction and poor cell functioning.

Also, research has shown that LLLT supports liver regeneration for more efficient waste disposal. This helps treat systemic inflammation and supports the workings of the immune system.

Consistency

LLLT is not an instant cure for any condition. You may experience relief after just one session, but the greatest results will come with time as the body’s cells regenerate and optimize their functioning. This can take a few weeks to a few months. Several sessions per week can help manage and minimize diabetic complications and keep the disease in remission on an ongoing basis.

Laser Acupuncture Treatment?

Acupuncture under traditional Chinese medicine is an alternative medicine that treats patients by needle insertion and manipulation at acupoints (APS) in the body. Acupuncture causes collagen fiber contraction, resulting in soluble actin polymerization and actin stress fiber formation, affecting the nervous and immune systems. Besides, acupuncture leads to molecular changes at APs in tissues at the cellular level. The local physicochemical reactions at the APs send signals to the organs via the tissue fluid and blood circulatory systems for optimal adjustment of the body’s organs.

It is believed to have been practiced for more than 2500 years, and this modality is among the oldest healing practices in the world. Acupuncture is based on the idea that living beings have Qi, defined as inner energy, and that it is an imbalance in Qi or interruption in the flow of Qi that causes illness and disease. Acupuncture therapy is focused on rebalancing the flow of Qi, and the practice is progressively gaining credibility as a primary or adjuvant therapy by Western medical providers.

Laser Acupuncture

Kaiyan Medical has been working to create ergonomic laser pens to simulate the acupuncture process. Laser acupuncture (LA) — non-thermal, low-intensity laser irradiation to stimulate acupuncture points — has become more common among acupuncture practitioners in recent years. LA is a safer, pain-free alternative to traditional acupuncture, with minimal adverse effects and greater versatility. LA has many features that make it an attractive option as a treatment modality, including minimal sensation, short duration of treatment, and minimal risks of infection, trauma, and bleeding complications.

What is the Difference

In acupuncture, needles are inserted at specific acupoints, which may be manually stimulated in various ways, including gentle twisting or up-and-down movements. Besides, the depth of needle penetration is also manipulated by the acupuncture practitioner. The patient may report sensations of De Qi, which are feelings of pressure, warmth, or tingling in the superficial layers of the skin. Many theories to explain how acupuncture works have been proposed, including the gate-control theory of pain and the endorphin-and-neurotransmitter. Others have postulated that acupuncture modulates the transmission of pain signals and alters the release of endogenous endorphins and neurotransmitters, resulting in physiologic changes.

One clear difference between needle acupuncture and LA is that LA does not physically penetrate the skin. Despite a greater understanding of LA, it is unclear how non-thermal, low-intensity laser irradiation stimulates acupoints. The mechanism of LA may be entirely separate from our present understanding of acupuncture. Current theories postulate that LLLT could positively affect modulating inflammation, pain, and tissue repair, given appropriate irradiation parameters.

Anti-Inflammatory Effect of Lasers

Inflammation reduction comparable to that of non-steroidal anti-inflammatory drugs has been reported with animal studies that used red and near-infrared LLLT, with laser outputs ranging from 2.5 to 100 mW and delivered energy doses ranging from 0.6 to 9.6 Joules. Human studies have shown similar anti-inflammatory effects with LLLT, which may account for many associated positive clinical results.

Cellular Effects of LLLT

LLLT improves cell physiology by increasing the overall cell redox potential toward greater oxidation and increased reactive oxygen species while simultaneously decreasing reactive nitrogen species. These redox state changes activate numerous intracellular-signaling pathways, including nucleic acid synthesis, protein synthesis, enzyme activation, and cell cycle progression.17 LLLT also alters the expression of genes that can enhance cell growth and inhibit cell apoptosis.16 These cellular effects of LLLT might reflect its ability to induce long-term changes in cells and LLLT’s benefits for wound healing, nerve regeneration, and inflammation reduction.

LLLT Characteristics

Red and infrared laser wavelengths are absorbed by cytochrome C oxidase protein in the mitochondrial cell membranes. This absorption is associated with increased adenosine triphosphate production by the mitochondria, which. In turn, it increases intracellular calcium (Ca2+) and cyclic adenosine monophosphate, which serve as secondary messengers that aid in regulating multiple body processes, including signal transfer in nerves and gene expression.

The power density of a laser, defined as laser energy supplied per area (W/cm2), influences its energy penetration depth. A 50-mW laser with a beam size of 1 cm2 has an energy density of 0.05 W/cm2. In contrast, the same power laser with a beam size of 1 mm2 has an energy density of 5 W/cm2 — a higher energy density results in deeper energy penetration through the skin.

Energy transmission through the skin is also affected by the absorption of light energy by skin structures. Light wavelengths from 650 to 900 nm have the best penetration through the skin. Lower wavelengths are absorbed by melanin and hemoglobin, and wavelengths longer than 900 nm are absorbed by water. With a well-focused laser beam, red wavelengths (~ 648 nm) can penetrate 2–4 cm beneath the skin surface, and infrared wavelengths (~ 810 nm) can penetrate up to 6 cm.

Now Kaiyan has made LLLT easier to use. Kaiyan medical devices can treat multiple acupoints simultaneously at the same time.


Bear, Wolf, Lion or Dolphin: How Understanding your Sleep Type Will Change your Life

Sleep is big business these days — one in three people are believed to experience sleep deprivation — and everyone is keen to rely on the latest fashionable theory.

For years, sleep cycles were divided into two categories. People who enjoy mornings were known as “early birds.” And those of us who prefer staying up late were labeled “night owls.”

Well, step-aside birds. Mammals are the new name of the game. That’s right; scientists now believe there are four ways to classify sleep/wake cycles. In the science world, these classifications are known as chronotypes.

Chronotypes describe the periods when your body wants to sleep and when it wants to be awake. And to make it easier, the chronotype categories are named after animals. Our natural sleep tendencies are now categorized as bear, wolf, lion, and dolphin.

It is crucial to understand your animal chronotype. Once you do, you can start to schedule your life around your body’s natural cycles. Kaiyan Medical suggests that this may help you sleep better and feel more productive at work.

Two Animals are not Enough

People have different circadian rhythms. That’s just a fact of life.

Science shows that:

“The human circadian system actively synchronizes to the 24-h day via environmental signals of light and darkness.”

Circadian? A 24-hour cycle. It’s your body clock. Sleep psychologists reckon they can determine our natural sleeping patterns. By understanding our own, we can have a happier, more productive life.

Now, Chronotype is a term that describes a person’s natural rhythm. And it doesn’t only relate to sleep. Chronotypes influence all primal instincts.

Author Michael Breus, Ph.D., recently suggested that there are 4 natural chronotypes. And he named these after 4 animals that follow similar sleep/wake patterns. So, say goodbye to night owls and early birds. Wolves, lions, bears, and dolphins are the new circadian rhythm mascots.


The Chronotypes

Check out the chronotypes below and let us know in the comment section which one sounds like you!

Wolves

Alright, night owls, this is your group. Just like these nocturnal creatures, you are most alert at night. Wolves tend to stay up later and struggle with waking up early.

Only about 15% of the population falls into this group. Wolves are more productive in the later afternoon and evening.

Sleep experts recommend that wolves set their alarm for 7 a.m. (snooze for 30 minutes) and go to sleep by midnight.

Lions

Lions are the new early birds. Like these wild cats, you are most alert in the morning. You have no trouble waking up and getting to work. But, lions tend to feel the afternoon slump. And by the evening, they feel drained.

About 15% of the population identifies as a lion. Sleep experts recommend that lions wake up around 5:30 a.m. and go to sleep by 10:30 p.m.

Bears

No, you don’t need to hibernate. But, like these diurnal (awake during the day, asleep at night) creatures, you follow the solar cycle. Bears generally feel awake during the day and need 8-hours of solid sleep at night.

About 50% of the population falls into this category. This group is productive in the morning and struggles with the mid-afternoon slump. Sleep experts recommend that bears wake up around 7 a.m. and go to sleep by 11 p.m.

Dolphins

Dolphins “only sleep with half of their brain at a time?” Sound familiar? Well, this is the insomniac (often self-diagnosed) group. You might be anxious and have trouble turning your brain off at night. Dolphins usually don’t get a complete night’s sleep.

About 10% of the population falls in this category. And even though they wake-up tired, dolphins are most productive by mid-morning.

Sleep experts recommend that dolphins get up around 6 a.m. and try to sleep around midnight.

Sleep Like an Animal

Who doesn’t want a better night’s sleep and a more productive day? Start scheduling your days based on your chronotypes! Once you know more about your chronotype, you can form sleep patterns that work with (not against!) your body’s natural rhythms.

So what are you waiting for? Here in Kaiyan, we are embracing our inner animals and start following our optimal sleep schedule.



Sources:

Fischer, Dorothee et al. "Chronotypes in the US – Influence of age and sex." PubMed, 21 Jun. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5479630/

Bellis, Rich. "How To Design Your Ideal Workday Based On Your Sleep Habits." Fast Company, 26 Nov. 2017, www.fastcompany.com/40491564/how-to-design-your-ideal-workday-based-on-your-sleep-habits

Levi, Anthea. "This Is the Best Time of Day to Do Everything, According to Your Chronotype." Health.com, 31 Oct. 2016, www.health.com/mind-body/how-to-get-more-energy-chronotype

Could Red Light Therapy be the Cure for Low Libido?

We’re animals of habit. When it comes to intimacy, it’s a night-time activity. Published findings on The Daily Mail discovered that most people have sex between 9:30 p.m. to 10:30 p.m. But what most people don’t realize is that for improved sex, you need the light.

Low libido (sex drive) has been a physical issue for both men and women. In the United States, sexual dysfunction affects 43% of women and 31% of men alone. However, further studies have shown this is a global issue. A study with 5,255 male participants from Croatia, Norway, and Portugal found that 14.4% reported a lack of sexual desire lasting two months or longer.

It’s clear low libido isn’t an issue within one gender; it’s a health concern that both men and women grapple with. For women, one survey at Hackensack University Medical Center, New Jersey, found that 36% of women between 18-to-3-years-old and 65% of women between 46-to-54-years-old reported low sexual desire.

But why are we losing our libido?

A loss of libido is a common issue linked to both the physical and the psychological self. Physical issues linked to low libido include low testosterone, alcohol and drug use, medication, and too little or too much exercise. At the same time, psychological issues can include stress, mental health, depression, and relationship issues.

Where do many of these problems stem from? Well, it certainly doesn’t help that we’re living our lives in overdrive: we’re working more; we’re chronically stressed, and generally living in ways that aren’t natural to our species.

However, where we live also plays a crucial role. Andrea Fagiolini, M.D., said, “In the Northern hemisphere, the body’s testosterone production naturally declines from November through April, and then rises steadily through the spring and summer with a peak in October. You see the effect of this in reproductive rates, with June showing the highest rate of conception.”

Since our body’s testosterone production naturally declines during winter and spring, many people are looking for treatment. As a result, many opt for hormone replacement therapy. It’s a controversial treatment that comes with a heavy dose of side effects, including prostate or breast cancer, sleep apnea, liver toxicity, and cardiovascular events.

Are people supposed to adjust to living with a low libido if they don’t want to undergo a dangerous treatment? Of course not. Luckily, red light therapy has been proven through various clinical studies to improve low libido levels.

At the University of Siena, Italy, scientists tested sexual and psychological responses to bright light. They discovered that regular, early-morning use of light therapy increases testosterone levels and sexual satisfaction.

So how does red light therapy increase testosterone in the body, exactly?

When your body is exposed to bright light, it produces a chemical called luteinizing hormone (LH). The more LH produced in the body leads to a higher testosterone increase, said the lead researcher Andrea Fagionlini, M.D.

Other studies in animals suggested that red light therapy influences Leydig cells — the body’s sperm producers located in the testicles.

“We found fairly significant differences between those who received the active light treatment and the controls,” Fagiolini stated. Dr. Brad Anawalt, an endocrinologist and professor of medicine at the University of Washington in Seattle provides two possible explanations for red light therapy’s effect on testosterone.

Since testosterone levels are the highest in the morning, a lack of daylight can reduce morning levels. Dr. Anawalt said, “[So] exposure to bright light might raise testosterone concentrations, leading to improved libido.” He added that “many men, and women, with low libido, suffer from depression. The bright light that mimics sunshine may help alleviate depression. Improved mood results in improved sex drive.”

Red light therapy can increase testosterone levels and reduce some of the causes of low libidos, such as depression, anxiety, and overall fatigue.

Lunas red light therapy panels have many benefits — even on our sex and love lives — which is an integral component to our well-being.

Stretch Marks & Light Therapy

Why Do We Get Stretch Marks?

A stretch mark is a type of scar called striae, meaning “thin, narrow scar”. In people who develop stretch marks, the skin has stretched faster than it can grow, such as during pregnancy, growth spurts, or rapid fat or muscle gain. The abrupt stretching causes the collagen and elastin proteins responsible for the skin’s structure and elasticity to rupture. This, in turn, causes the dermis to tear.

As the dermis tears, the body’s healing mechanisms spring into action to close the wound as quickly as possible to prevent infection and further damage.

Normally, as the skin regenerates and grows, it’s an elegantly organized latticework of collagen and elastin proteins. But when the skin tears, the body doesn’t have time to build an elegant structure to fill in the gap. Time is of the essence in any wound repair, including torn skin.

The collagen clumps together hurriedly, aiming for efficient closure of the wound before infection can set in. “Scarring is the result of a system that has learned to respond extremely quickly to a wound,” says Dr. John Newman, a cosmetic surgeon and researcher at the Laser Center of Virginia in Virginia Beach.

This haphazard process results in tough and functional but unattractive tissue — what we know as a scar. “It is kind of like nailing down a crisscross of two-by-fours over a hole in a deck,” says Newman. “It seals the hole, but it doesn’t look very nice.”

Newly formed stretch marks are darker than the surrounding skin and can be slightly raised, itchy, or painful. If they’re left untreated, they become permanent scars. Their color will lighten, and their appearance will fade below the top layer of the surrounding skin.

The bigger mystery is why stretch marks don’t disappear over time as the skin regenerates. The key lies in the information that emerging cells receive from adult cells in the area. Skin cells, whether they’re normal cells or scar cells, regenerate about once every 30 days. Growth of new skin cells begins at the bottom-most layer of the scar, and older (dying) cells are pushed to the surface where they naturally slough off.

However, Neuman explains that that that that emerging cells “learn” from their immediate neighbors and predecessors and develop the same characteristics as ir replacement their replacement cells. As a result, any emerging cell in contact with scar cells will become new scar tissue rather than normal skin tissue.

Red Light Therapy For Stretch Marks

If you have tried to get rid of stretch marks, perhaps you’ve used specialized creams that contain retinoids. These work to some extent, but only if you catch your stretch marks early and treat them while they’re still forming. Retinoids work by stimulating collagen production. However, they can irritate sensitive individuals, and doctors often recommend that pregnant women avoid anything containing retinoids.

Another common treatment, known as microdermabrasion, essentially involves “sandblasting” the skin with tiny crystals. This sloughs off dead skin

cells and stimulates the production of collagen. Microdermabrasion is a fairly harsh treatment that can lead to irritation and damage, especially to sensitive skin.

The most extreme treatment for stretch marks is plastic surgery, such as a mini tummy tuck. This may be effective, but there are risks associated with any invasive procedure and the high cost.

Is there a better option for restoring the appearance of the skin? The answer is yes, absolutely. Also known as photobiomodulation and low-level light therapy (LLLT), red light therapy improves skin appearance, reduces signs of aging, treats chronic skin conditions, reduces scarring, and promotes skin wound healing.

When red light therapy is used, visible red light and invisible near-infrared (NIR) light are applied to the skin with LED bulbs' devices. Wavelengths of light are measured in nanometers (nm), with red light ranging from 630nm to 660nm and NIR light ranging from 810nm to 850nm. Human cells respond favorably to these wavelengths, similar to how natural sunlight affects plant cells by stimulating more energy and optimization of cell function.

When the red light is shone on bare skin, it soaks into the mitochondria, colloquially referred to as the powerhouses of cells' energy factories. The mitochondria are, in turn, stimulated to produce more adenosine triphosphate (ATP), which is the primary cellular fuel. This energizes cells to perform their normal functions, from fighting off pathogens to performing repair and regeneration.

Improved Blood Flow

Proper healing relies on good circulation to the skin. Red light promotes the proliferation of endothelial cells, which make up the inner layer of capillaries (the tiny blood vessels that deliver oxygen and nutrients throughout the body). This was the focus of a 2017 study by a team of researchers from Austria, who found that red light consistently increased migration and proliferation of endothelial cells.

Without proper blood circulation, there would be no healing since endothelial cells also deliver white blood cells to the sites they need. In skin wound healing, white blood cells are necessary to protect the vulnerable area from infection while the wound closes up.

Reduced Inflammation

Acute inflammation results in the redness that’s noticeable in fresh stretch marks. This is a normal and necessary part of the tissue regeneration scar's process. Acute inflammation, which is a function of the immune system, actually sets the stage for normal tissue repair and regeneration. Inflammation is quickly followed by the production of new skin structures — which, as previously described, are hastily assembled to ensure that the torn skin doesn’t become infected.

But sometimes, the inflammatory process continues after the wound has healed, leading to chronic inflammation. It can lead to a variety of widespread problems throughout the body, including disease. “Some inflammation is good,” says Dr. Robert H. Shmerling, an associate professor of medicine at Harvard Medical School. “Too much is often bad. The goal is to recognize when inflammation is simply doing its job, and when it can potentially cause problems.”

Hundreds of studies have shown how red light therapy can significantly reduce inflammation. Many of these were conducted by Dr. Michael A. Hamblin, an associate professor of dermatology at Harvard Medical School and a noted expert on red light therapy. In the final report of a 2017 study, Hamblin refers to red light therapy’s “pronounced anti-inflammatory effects.”

Mobilize Stem Cells

During the skin-rebuilding phase, stem cells, which are unspecialized “master” cells, mobilize to the site and develop into most any type of specialized cells that are needed by the body. Ideally, they develop into normal skin cells, rather than scar tissue, to replenish damaged or destroyed cells due to skin tearing.

Red light has been shown to activate stem cells. As Barbara Gefvert, editor-in-chief of BioOptics World, explains: “Recent research shows … that noninvasive application of light can boost the natural growth of an individual’s own stem cells to enable exciting new treatments.” Stem cells can assist with the tissue regeneration process and stimulate normal and healthy behavior in existing cells. This can prevent the formation of new stretch marks and gradually reduce the appearance of existing stretch marks.



Photodynamic Therapy for Cancer

Photodynamic therapy (PDT) is a treatment that uses a drug, called a photosensitizer or photosensitizing agent, and a particular type of light. When photosensitizers are exposed to a specific wavelength of light, they produce a form of oxygen that kills nearby cells

Each photosensitizer is activated by light of a specific wavelength. This wavelength determines how far the light can travel into the body. Thus, doctors use specific photosensitizers and wavelengths of light to treat different areas of the body with PDT.

How is PDT Used to Treat Cancer?

In the first step of PDT for cancer treatment, a photosensitizing agent is injected into the bloodstream. The agent is absorbed by cells worldwide but stays in cancer cells longer than it does in normal cells. Approximately 24 to 72 hours after injection, when most of the agent has left normal cells but remains in cancer cells, the tumor is exposed to light. The photosensitizer in the tumor absorbs the light and produces an active form of oxygen that destroys nearby cancer cells.

In addition to directly killing cancer cells, PDT appears to shrink or destroy tumors in two other ways. The photosensitizer can damage blood vessels in the tumor, thereby preventing cancer from receiving necessary nutrients. PDT also may activate the immune system to attack the tumor cells.

The light used for PDT can come from a laser or other sources. Laser light can be directed through fiber optic cables (thin fibers that transmit light) to deliver light to areas inside the body. For example, a fiber optic cable can be inserted through an endoscope (a thin, lighted tube used to look at tissues inside the body) into the lungs or esophagus to treat cancer in these organs. Other light sources include light-emitting diodes (LEDs), which may be used for surface tumors, such as skin cancer.

PDT is usually performed as an outpatient procedure. PDT may also be repeated and used with other therapies, such as surgery, radiation therapy, or chemotherapy.

Extracorporeal photopheresis (ECP) is a type of PDT in which a machine is used to collect the patient’s blood cells, treat them outside the body with a photosensitizing agent, expose them to light, and then return them to the patient. The U.S. Food and Drug Administration (FDA) has approved ECP to help lessen the severity of skin symptoms of cutaneous T-cell lymphoma that has not responded to other therapies. Studies are underway to determine if ECP may have some application for other blood cancers and help reduce rejection after transplants.

What Types of Cancer are Currently Treated with PDT?

To date, the FDA has approved the photosensitizing agent called porfimer sodium, or Photofrin®, for use in PDT to treat or relieve the symptoms of esophageal cancer and non-small cell lung cancer. Porfimer sodium is approved to relieve esophageal cancer symptoms when cancer obstructs the esophagus or when cancer cannot be satisfactorily treated with laser therapy alone. Porfimer sodium is used to treat non-small cell lung cancer in patients for whom the usual treatments are not appropriate and relieve symptoms in patients with non-small cell lung cancer that obstruct the airways. In 2003, the FDA approved porfimer sodium to treat precancerous lesions in patients with Barrett esophagus, a condition that can lead to esophageal cancer.

What are the Limitations of PDT?

The light needed to activate most photosensitizers cannot pass through more than about one-third of an inch of tissue. For this reason, PDT is usually used to treat tumors on or just under the skin or on the lining of internal organs or cavities. PDT is also less effective in treating large tumors because the light cannot pass far into these tumors. PDT is a local treatment and generally cannot treat cancer that has spread.

Does PDT have any Complications or Side Effects?

Porfimer sodium makes the skin and eyes sensitive to light for approximately 6 weeks after treatment. Thus, patients are advised to avoid direct sunlight and bright indoor light for at least 6 weeks.

Photosensitizers tend to build up in tumors, and the activating light is focused on the tumor. As a result, damage to healthy tissue is minimal. However, PDT can cause burns, swelling, pain, and scarring in nearby healthy tissue. Other side effects of PDT are related to the area that is treated. They can include coughing, trouble swallowing, stomach pain, painful breathing, or shortness of breath; these side effects are usually temporary.

What Does the Future Hold for PDT?

Researchers continue to study ways to improve the effectiveness of PDT and expand it to other cancers. Clinical trials (research studies) are underway to evaluate PDT's use for cancers of the brain, skin, prostate, cervix, and peritoneal cavity (the space in the abdomen that contains the intestines, stomach, and liver). Other research is focused on the development of more powerful photosensitizers, more specifically target cancer cells, and are activated by light that can penetrate tissue and treat deep or large tumors. Researchers are also investigating ways to improve equipment and the activating light's delivery.

Lighting the Way Back for Astronauts - Light Therapy & NASA

In 1993, Quantum Devices, Inc. (QDI), of Barneveld, Wisconsin, began developing the HEALS (High Emissivity Aluminiferous Light-emitting Substrate) technology high-intensity, solid-state LED lighting systems for NASA Space Shuttle plant growth experiments. The company evolved out of cooperative efforts with the Wisconsin Center for Space Automation and Robotics (WCSAR) at the University of Wisconsin-Madison — a NASA center for the Commercial Development of Space. Ronald W. Ignatius, QDI’s president, and chairman represented one of WCSAR’s industrial partners at the time. WCSAR was conducting research on light sources for promoting food growth within closed environments where humans would be present for a long duration, such as the Space Shuttle and the International Space Station.

With the support of WCSAR, Ignatius experimented with LEDs, which provide high-energy efficiency and virtually no heat, despite releasing waves of light 10 times brighter than the Sun. Ignatius admits that some scientists involved in the project were skeptical at first, thinking that the idea of using LEDs to promote plant growth was far-fetched. However, the experiments demonstrated that red LED wavelengths could boost the energy metabolism of cells to advance plant growth and photosynthesis. This finding prompted Ignatius to develop a line of LED products that emit the exact wavelength of light that plants use in photosynthesis.

“Our company gives credit to Dr. Ray Bula, the director of WCSAR, for having the foresight to go against the prevailing dogma of the time and design the first plant experiment using monochromatic light to grow lettuce plants,” Ignatius proclaims.

In 1989, Ignatius formed QDI to bring the salt grain-sized LEDs to market. In October 1995, the light sources made their Space Shuttle flight debut on the second U.S. Microgravity Laboratory Spacelab mission (STS-73, Columbia).

Growing

When NASA determined that red LEDs could grow plants in space, Marshall Space Flight Center awarded QDI several Small Business Innovation Research (SBIR) contracts to investigate the broad-spectrum diodes' effectiveness in medical applications. The contracts, issued from 1995 to 1998, focused on increasing energy inside human cells. NASA hoped that the LEDs would yield medical benefits on Earth and stem bone and muscle mass loss in astronauts, which occurs during long periods of weightlessness. (In space, the lack of gravity keeps human cells from growing naturally.) Furthermore, since wounds are slow to heal in a microgravity environment, LED therapy could accelerate healing and keep what would be termed as minor wounds on Earth from becoming mission-catastrophic in space.

In addition to promoting cell growth, the red LEDs are capable of activating light-sensitive, tumor-treating drugs that, when injected intravenously, could destroy cancer cells while leaving surrounding tissue virtually untouched. The technique, approved by the U.S. Food and Drug Administration (FDA) for use in laboratory and human trials, is known as Photodynamic Therapy.

With the SBIR assistance from NASA, QDI set out to alter a surgical probe that could emit long waves of red light to stimulate a Benzoporphyrin-derivative drug called Photofrin, which delivers fewer post-operative side effects than comparable drugs. Ignatius also developed a friendly and successful working relationship with Dr. Harry Whelan, pediatric neurology and director of hyperbaric medicine at the Medical College of Wisconsin in Milwaukee. The two had met after Ignatius came across a newspaper article highlighting Whelan’s ground-breaking brain cancer surgery technique, which uses drugs stimulated by laser lights to accelerate healing. Accordingly, QDI provided more than $1.25 million from its SBIR contracts to support Whelan’s pioneering photobiomodulation research and bring him on board to help improve the surgical probe.

Collectively, Ignatius, Whelan, and researchers from NASA successfully altered the probe for pediatric brain tumors and the prevention of oral mucositis (a common side effect of chemotherapy and radiation treatments) in pediatric bone marrow transplant patients at the Medical College of Wisconsin. In May 1998, a 20-year-old female became the first patient to undergo surgery with the modified probe. The young woman had endured six brain surgeries and chemotherapy and radiation treatments over a span of 10 years, but her aggressive cancer kept coming back. Having exhausted all of her conventional treatment options, she turned to the NASA-sponsored Photodynamic Therapy technology.

During the procedure, surgeons excised as much of the recurring brain tumor as they could then injected the light-activated Photofrin into her bloodstream and inserted the LED probe into the remaining tumor tissue. The probe, which casts long wavelengths that generate less heat and penetrate deeper into tissue than the shorter wavelengths of traditional medical lasers, proved to be both safe and effective, as the tumor never returned, and the patient recovered with no complications. A second operation that took place 3 months later on a male patient was also deemed successful by Whelan and his Medical College of Wisconsin surgeons' team.

FDA-approved clinical trials continued at several other facilities over the next 3 years, including the Roswell Park Cancer Institute in Buffalo, New York; Rush-Presbyterian-St. Luke’s Medical Center in Chicago; and the Instituto de Oncologia Pediatrica in Sao Paulo, Brazil. QDI became recognized as a U.S. Space Foundation “Space Technology Hall of Fame” award recipient in 2000 and a Marshall Space Flight Center “Hallmark of Success” in 2004.

Product Outcome

The positive clinical trial results and continued support from NASA and follow-on research grants from the Defense Advanced Research Projects Agency helped QDI and the Medical College of Wisconsin fully transition space technology into a new, non-invasive medical device. The WARP 10 (Warfighter Accelerated Recovery by Photobiomodulation) is a high-intensity, hand-held, portable LED unit intended for the temporary relief of minor muscle and joint pain, arthritis, stiffness, and muscle spasms. It also promotes the relaxation of muscle tissue and increases local blood circulation. Unlike the surgical probe, the WARP 10 does not require intravenous medicine; instead, the unit can be placed directly on the skin where treatment is to occur.

The WARP 10 was designed to aid armed forces personnel on the front lines with immediate first aid care for minor injuries and pain, thereby improving combat endurance. The “soldier self-care” device produces 80 times more photon energy than a 250-Watt heat lamp, yet it remains cool to the touch. The power advantage reduces the time required for each therapeutic dose and provides for faster multi-dose exposures when needed, without the harmful effects of ultraviolet solar radiation. The U.S. Department of Defense and the U.S. Navy are currently issuing WARP 10 to crews on submarines and Special Forces operations.

QDI has introduced an FDA-approved consumer version sharing the same power and properties of the military model as an alternative to the cost and complications associated with the overuse of non-steroidal anti-inflammatory drugs (NSAIDs) for persistent pain relief. According to a Mayo Clinic study, adverse events associated with the use of NSAIDs are reported more frequently to the FDA than such events associated with any other group of drugs. Furthermore, conservative calculations for the United States estimate that approximately 107,000 patients are hospitalized each year for NSAID-related gastrointestinal complications. At least 16,500 NSAID-related deaths occur annually among arthritis patients alone, according to compiled research.

References

Beauvoit B., Evans S.M., Jenkins T.W., Miller E.E., Chance B., “Contribution of the Mitochondrial Compartment to the OpticalProperties of the Rat Liver: A Theoretical and Practical Approach,” Analytical Biochemistry 226, 167-174 (1995).Beauvoit B., Kitai T., Chance B., “Correlation between the Light Scattering and the Mitochondrial Content of Normal Tissues andTransplantable Rodent Tumors,” Biophysical Journal 67, 2501-25 10 (1994).Chance B., Nioka S., Kent J., McCully K., Fountain M., Greenfield R., Holtom G., “Time-Resolved Spectroscopy of Hemoglobin andMyoglobin in Resting and Ischemic Muscle,” Analytical Biochemistry 174, 698-707 (1988)Conlan M.J., Rapley J.W., Cobb C.M., “Biostimulation of wound healing by low-energy laser irradiation,” J.Clin. Periodont. 23, 492-496 (1996).Eggert H.R., Blazek V., “Optical Properties of Normal Human Brain Tissues In The Spectral Range of 400 to 2500 nm,” Advances inExperimental Medicine & Biology 333, 47-55 (1993).Karu T., “Photochemical Effects Upon the Cornea, Skin and Other Tissues (Photobiology Of Low-Power Laser Effects,” HlthPhysics 56, 69 1-704 (1989).Lubart R., Friedman H., Sinyakov M., Cohen N., Breitbart H., “Changes in Calcium Transport in Mammalian Sperm Mitochondriaand Plasma Membranes Caused by 780 nm Irradiation,” Lasers in Surg & Med 21, 493-499 (1997).Lubart R., Wollman Y., Friedman H., Rochkind S. Laulicht L., “Effects of visible and near-infrared lasers on cell cultures,” Journalof Photochemistry & Photobiology 12(3), 305-3 10 (1992).Salansky N., “Low energy photon therapy for wound healing.” Intnl Med Instr, Canadian Defense Ministry, PersonalCommunication. (1998).Schmidt M.H., Bajic D.M., Reichert K.W. II, Martin T.S., Meyer G.A., Whelan H.T., “Light –emitting diodes as a light source forintra-operative photodynamic therapy.” Neurosurg 38(3), 552-556 (1996).Schmidt M.H., Reichert K.W. II, Ozker K., Meyer G.A., Donohoe D.L., Bajic D.M., Whelan N. T., Whelan H. T., “PreclinicalEvaluation of Benzoporphyrin Derivative Combined with a Light-Emitting Diode Array for Photodynamic Therapy ofBrain Tumors.” Pediatr Neurosurg 30, 225-231 (1999).Whelan H.T., Schmidt M.H., Segura A.D., McAuliffe T.L., Bajic D.M., Murray K.J., Moulder J.E., Strother D.R., Thomas J.P., MeyerG.A., “The role of photodynamic therapy in posterior fossa brain tumors: A pre-clinical study in a canine glioma model.”Journal of Neurosurgery 79(4), 562-8 (1993).5Whelan H.T., Houle J.M., Donohoe D.L., Bajic D.M., Schmidt M.H., Reichert K.W., Weyenberg G.T., Larson D.L., Meyer G.A.,Caviness J.A., “Medical Applications of Space Light-Emitting Diode Technology—Space Station and Beyond.” SpaceTech. & App Int’l Forum 458, 3-15 (1999).Yu W., Naim J.O., Lanzafame R.J., “The Effect Of Laser Irradiation On The Release Of bFGF From 3T3 Fibroblasts.”Photochemistry & Photobiology 59, 167-70 (1994).

How Red Light Therapy Combats Arthritis Pain & Stiffness

When it comes to muscle and joint stiffness, osteoarthritis, and arthritis, the one thing in common is pain and inflammation. When suffering from joint and muscular conditions, a person’s range of motion decreases, and swelling and skin redness increase, making everyday tasks a struggle.

Many young to middle-aged people are unaware of these conditions as they’ve been labeled as conditions mainly for the elderly; however, things have changed.

Though these conditions are common within the elderly community, we’re seeing an increase among young adults. In the United States alone, 23% of adults — over 53 million people — have arthritis, according to the Centers for Disease Control and Prevention (CDC). In other words, joint pain isn’t just for old age, as we once thought.

Rheumatoid arthritis (RA) appears in every 8 in 100,000 people between 18 and 34 years old. Of course, no one — young or old — wants to wake up feeling joint stiffness, swelling, or pain every morning.

However, the old myth that arthritis is untreatable is about to be debunked with light therapy.

Naturally, a medical professional will have to make a conclusive arthritis diagnosis. However, once diagnosed, many people find home treatments to deal with the pain — like light therapy. And the people who are undergoing light therapy are receiving incredible pain relief from their treatment. For example, a study published in the Turkish Journal of Physical Medicine and Rehabilitation found that infrared light treatment on inflammatory arthritis of the spine (spondylitis) encouraged increased function and improved quality of life for participants.

But what’s the science behind red light therapy treating joint conditions? Red light therapy uses low levels of red light to stimulate a natural response to cell performance. The light penetrates through the layers of the dermis, entering the muscles and nerves. As the cells absorb the energy, they become more active, with increased blood flow to the treated area, promoting cell regrowth and regeneration. Through this combination of increased blood flow and cellular activity, it rapidly reduces inflammation and pain.

With the recent advancements in modern technology, those who have arthritis or other joint conditions no longer need to opt for nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids. These forms of the medication come with serious side effects such as edema, heartburn, stomach ulcers, cataracts, bone loss, and elevated blood clots. This alternative non-invasive treatment allows people to choose a drug-free treatment that reduces swelling, inflammation, and pain through red light therapy.

A study published in the National Library of Medicine found that elderly patients who underwent red and infrared therapy treatment had reduced their pain by 50%. Besides, they found participants who underwent red and infrared light therapy had a significant improvement in function. Another study from 2016 saw a substantial reduction in pain and an increased range of motion after five to seven red light therapy treatments for Bouchard’s and Heberden’s osteoarthritis. These studies are only a few examples of how red light therapy shows results as an effective treatment.

A little red light can go a long way for your body, mind, and soul. More and more people recognize the benefits of red light therapy as a natural home treatment. For people suffering from any joint condition, red light therapy will reduce inflammation, eliminating joint and muscle pain.

But there’s more to red light therapy than this. It’s important to be reminded that light therapy also heals other ailments in the body. Red light therapy is effective for injuries, muscle recovery, cancer side effects, skincare, and depression.

With an FDA-approved and MDA-certified Lunas red light therapy device, users can achieve optimal therapeutic results by merely exposing their bare skin to the light for a few minutes per day. Healing yourself doesn’t need a lot of time or money; you need the right tools. Lunas light therapy devices have the power to heal bodies and minds all around the world.

Red Light Therapy and Quarantine

If there’s one thing most of us likely haven’t had enough of in 2020, it’s natural light. The pandemic has changed our lives in so many ways, particularly concerning the drastic increase in the amount of time spent indoors and home. Most of us are stationed at our computers all day, only to log off just in time for dinner. At that point, it’s already dark, and we’re likely ready to decompress and relax.

Throw a lockdown on top of this, and we’re lucky if we even get to see the sky that day.

Our current lifestyle, specifically in quarantine, makes natural daylight a rare sight, and this can be extremely detrimental to our mental and physical health — but why?

Without a sufficient amount of light, your circadian rhythm becomes out of sync, as does our hormone production levels. And if you’ve been experiencing poor sleep, lack of light is likely the reason why. A study from the Journal of Clinical Sleep Medicine found that employees who work near windows receive twice as much sunlight as those who don’t receive natural light — they also receive 46 more minutes of sleep on average.

So: darkness isn’t the determiner of sleep; rather, light is.

It’s clear how our daily routines have become more indoors-bound, yet there seems to be no way to reduce these light-limiting circumstances. The lack of sleep disrupted hormones, and constant uncertainty has a severe effect on our bodies, which we’re all experiencing during this time. So, how do we overcome these health concerns with limited options?

This is where red light therapy plays a crucial role in improving health. With the average American spending 90 percent of their time indoors, red light therapy allows you to receive light in your own environment. But just because we’re staying at home due to quarantine doesn’t mean we can’t supplement the natural light we need.

Red light therapy works by increasing energy production at a cellular level. The more energy our cells produce, the better our bodies feel as there’s sufficient blood flow. However, there’s more to it than just feeling good.

For people working in front of the computer all day, carpal tunnel syndrome, muscle fatigue, and arthritis are serious concerns. And since we’re working from home, our screen time has significantly increased. Red light therapy can also alleviate these issues by increasing circulation, repairing tissue, and relieving stiffness.

And while some may have received more natural light during quarantine in the summer, winter is right around the corner. During the winter months, Seasonal Affective Disorder (SAD) affects around 5% of people in general. However, with quarantine, these numbers are increasing. Thankfully, SAD symptoms can be significantly reduced, as light therapy mimics the sun’s light.

With COVID-19, it’s also incredibly difficult to manage mental and emotional health with the current circumstances. Before quarantine, if someone was stressed, they could reduce their symptoms by working out, going to yoga class, or enjoying nature with friends. But these activities have been either eliminated or significantly reduced. So, the reality is that we’re sitting at home all day, stressed, overworked, and fatigued.

Red light therapy is a game-changer for mitigating stress levels, as light cultivates calmness within the body. And since light therapy aids with cell production, it helps the body bounce back after experiencing stress or illness. In these times, red light therapy can aid with stress and help people recover from COVID-19 by reducing lung inflammation, pneumonia, and other acute respiratory disorders.

So although the quarantine presents many new challenges, we can be empowered to control our own health and wellness during these times. At Lunas, we’re passionate about helping people achieve their balance and intend to have our light panels in homes around the world, particularly during this challenging period. We hope to help everyone around the world find their light — literally!



Light and the Moon

The moon shines because its surface reflects light from the sun. And even though it sometimes seems to shine very brightly, the moon reflects only between 3 and 12 percent of the sunlight that hits it.

The moon’s perceived brightness from Earth depends on where the moon is in its orbit around the planet. The moon travels once around Earth every 29.5 days, and during its journey, it’s lit from varying angles by the sun.

This moon’s movement around the Earth — and the simultaneous orbiting of Earth around the sun — account for the moon’s different phases (full moon, quarter moon, etc.). At any given point in the moon’s trajectory around the Earth, only half of its surface is facing the sun, and therefore, only half of the moon is lit up. The other half of the surface faces away from the sun and is in shadow.

Now, I took my first moonlight photograph in 1998, using my father’s old Kodak camera. The results were almost invisible, of course. It was pretty clear that I had no idea what I was doing. But I did know that the feeling of being out under the stars was one that I needed to capture somehow, and I had to find a way to go about doing it.

I left the moonlight photography for a while. Some years later, I read that the brightness of moonlight is extremely variable over a range of many stops and that it was nearly impossible to figure out the brightness of a given scene was going to be ahead of time. The brightness of moonlight under clear skies is as easily predictable as is the brightness of sunlight under similar conditions.

Several things cause moonlight brightness to vary. The most obvious is the moon’s phase. The brightness of moonlight varies by approximately a factor of 10 between the quarter phase and full moon, based on a diffuse reflection and the geometry of the positions of the earth, sun, and moon alone. This is about three and a half stops of light, which is substantial. Another factor is the distance between the earth, moon, and sun, which changes due to the earth and lunar orbits not being perfect circles. The distance from the earth to the sun varies from 0.9833 Astronomical Units at perihelion to 1.0167 Astronomical Units at aphelion. The earth’s distance to the moon varies from 356,400 kilometers at extreme perigee to 407000 kilometers at extreme apogee. The amount of light that falls on a body varies with the inverse square of the distance from the light source, so the combined effect of these distance variations can be quite pronounced. The range of lunar illumination variation is 6.9% for variation in sun distance and 30% for moon distance variation. This amounts to about one-third stop of brightness, which enough to change the mood of a photo when slide films are used.

The third factor in moonlight brightness is the so-called opposition effect. The surface of the moon is covered with small glassy particles that can serve as wonderful retro-reflectors. If you are within a small angle to the line between the sun and moon, the amount of light coming from the moon increases dramatically relative to what you would expect from a diffuse reflection alone. There is quite a range in the magnitude of this effect presented in scientific literature, ranging from a factor of 1.35 to 20! Whatever value you choose to use, the effect is at least one-third stop of light, making it significant to use slide film.

The final parameter that introduces variation into moonlight brightness is atmospheric attenuation, or atmospheric extinction, to use astronomer’s jargon. This accounts for the amount of light absorbed or scattered when light from the moon passes through the earth’s atmosphere. There are two factors involved: the amount of reduction per a given amount of air transited by the light (the “extinction coefficient”) and the amount of air in the light path (“air mass”). Three principal phenomena contribute to the extinction coefficient: molecular absorption, molecular (Rayleigh) scattering, and aerosols’ scattering (particles larger than molecules). See my web page on atmospheric attenuation for more on these individual factors. Overall, an extinction coefficient value is small for dry, clear air but can be huge for moist, dusty air. And the amount of air the light passes through can vary from one “air mass” with the moon directly above you to forty “air masses” when the moon is on the horizon.

So how bright can moonlight be? The brightest moonlight occurs with the moon at perigee and the earth at perihelion, right at the full moon phase. You can never have the moon at its theoretically fullest phase, right opposite the earth from the sun, because whenever the moon goes there, it enters the earth’s shadow, and we get a lunar eclipse! But assuming the eclipse didn’t happen, we could assume the following: a phase angle of zero, apparent air with an “extinction coefficient” of 0.11 magnitudes per air mass, the moon on the zenith so that the moonlight passes through a single “air mass,” the brightness would be 0.0462-foot-candles (LV -2.0), neglecting “the opposition effect.” If we include “the opposition effect,” the brightness could be anywhere from 35% to 20 times brighter (note that 35% is the more accepted value in the scientific literature, which would give an LV of -1.7). I once measured moonlight brightness with a Gossen Luna-Pro incident light meter in mid-winter on the Kelso Dunes at LV=-2.2, so this is a believable result.

There is a rule of thumb, sometimes called the Looney 11 Rule, which says we should treat the moon as being 250,000 times dimmer than the sun. This would have us use a shutter speed 18 stops slower than the 1/(film speed) value that is used in the “Sunny 16 Rule”, which works out to about 44 minutes at f/16 under moonlight conditions with the film having an ISO speed rating of 100 (uncorrected for reciprocity failure!). This is close enough to be useful under full moonlight conditions given an average earth-moon and earth-sun distance, with the moon high in the sky and clear air. Actually, since the sun has an astronomical visual magnitude of -26.74 and the full moon an astronomical visual magnitude of -12.73, the sun is more like 402,000 times brighter than the moon 18.6 stops. Thus using this rule pretty much ensures a minimum of 2/3 stop underexposure — which may actually be fine, since most of the time you want an underexposure to give the impression of the night in the image.

Surprisingly, the moonlight is actually a slightly warmer color than sunlight, as the moon reflectance is higher for longer wavelengths. Yet, on clear nights, with the full moon high in the sky (as little atmospheric influence as possible), the landscape around us appears blueish because of the Purkinje effect: at low illumination levels, our red color sensitivity decreases (as our vision system gradually switches from daylight (cones) to night time vision (using rod cells)).

That’s why the sunlight looks “warm” (more yellow), and the moonlight looks “cold” (bluer — because the insufficient light level changes our color perception), even though the real colors are pretty much the same.

In fact, this is can even become a real problem when taking very long exposure photos at night! They look almost like daylight photos, destroying the intended atmosphere of mystery. Objectively, the photograph is correct, but it is not what we see with our own eyes. Add some blue tint and the night feeling is back.

References

The Sun and Us

Nothing is more important to us on Earth than the Sun. Without the Sun’s heat and light, the Earth would be a lifeless ball of ice-coated rock. The Sun warms our seas, stirs our atmosphere, generates our weather patterns, and gives energy to the growing green plants that provide the food and oxygen for life on Earth.

We know the Sun through its heat and light, but other, less obvious aspects of the Sun affect Earth and society. Energetic atomic particles and X-rays from solar flares and other disturbances on the Sun often affect radio waves traveling the Earth’s ionosphere, causing interference and even blackouts of long-distance radio communications. Disturbances of the Earth’s magnetic field by solar phenomena sometimes induce huge voltage fluctuations in power lines, threatening to blackout cities. Even such seemingly unrelated activities as the flight of homing pigeons, transatlantic cable traffic, and the control of oil flow in the Alaska pipeline apparently are interfered with by magnetic disturbances caused by events on the Sun. Thus, understanding these changes — and the solar events that cause them — is important for scientific, social, and economic reasons.

We have long recognized the importance of the Sun and watched it closely. Primitive people worshiped the Sun and were afraid when it would disappear during an eclipse. Since the early seventeenth century, scientists have studied it with telescopes, analyzing the light and heat that manage to penetrate our absorbing, turbulent atmosphere. Finally, we have launched solar instruments and ourselves-into space to view the Sun and its awesome eruptions in every aspect.

Once we looked at the Sun by the visible light that reached the ground, it seemed an average, rather stable star. It was not exactly constant, but it seemed to vary in a fairly regular fashion, with a cycle of sunspots that comes and goes in about eleven years. Now the Space Age has given us an entirely different picture of the Sun. We have seen the Sun in other forms of light-ultra violet, X-rays, and gamma rays that never reach the ground from space. This radiation turns out to be far more responsive to flare eruptions and other so-called solar activity.

We now see the Sun as a place of violent disturbances, with wild and sudden movements above and below its visible surface. Besides, solar activity's influence seems to extend to much greater distances than we had believed possible. New studies of long series of historical records reveal that the Sun has varied in the past in strange and unexplained ways. Scientists wonder how such variations might affect the future climate on Earth.

We have obtained a clearer picture of the scope of the Sun’s effects. Its magnetic field stretches through interplanetary space to the outer limits of the solar system. Steady streams and intense storms of atomic particles blow outward from the Sun, often encountering our Earth's atmospheres and the other planets. The spectacular photos of the Earth from space show only part of the picture. Instruments carried on satellites reveal a wide variety of invisible phenomena — lines of magnetic force, atomic particles, electric currents, and a huge geocorona of hydrogen atoms — surrounding the Earth. Each is as complex and changing as the visible face of the globe. The Earth’s magnetic field extends tens of thousands of miles into space, and many different streams of electrons and protons circulate within it. Huge electric currents flow around the Earth, affecting their high-altitude surroundings as well as our environment at ground level.

Space observations have greatly expanded our ability to look at the Sun, interplanetary space, and the Earth's immediate surroundings. We can now “see” many phenomena that are completely undetectable from the Earth’s surface, and we now have a much better, more complete, and more coherent picture of how events in one part of our solar system relate to activity in another.

The Sun as a Star

We sometimes forget that there is one star that is easily visible in the day time: our Sun. The Sun is the only star close enough to be studied in detail, but we are confident that all the processes in the Sun must also occur in billions of distant stars throughout the universe. To understand the nature and behavior of other stars, we must first understand our own. At the same time, observations of other kinds of stars help put the Sun in perspective.

The Sun is a relatively typical star among the approximately 100 billion stars in our Milky Way galaxy. The masses of most other stars that we see range from approximately one-tenth of the mass of the Sun to about 30 solar masses. The surface temperatures of most stars range from about 2000° C to 40,000° C. Although the Sun is somewhat on the cool side at about 6000° C, hot stars are rare, and most normal stars are cooler than the Sun. Compared to some of the explosive stars — novae, and supernovae — which sometimes appear in the sky, the Sun is stable and ordinary.

This long-term stability of our Sun probably was crucial for the development of life on Earth. Biologists believe that a relatively stable average temperature had to prevail on Earth during the past 3 billion years for life to evolve to its present state. The relative stability of the Sun is also important to astronomers trying to understand the basic nature of it and other stars. Violent activity in the Sun could mask the more subtle and long-enduring processes, which are the basic energy transport mechanisms of our star. Fortunately, they are not hidden, and we have been able to map the trend in solar properties with height above the visible surface.

Above the minimum temperature region in the photosphere, we have measured how the gas gets hotter as it thins out with height. The chromosphere and corona, each hotter than the layer below, are warmed by the transfer of energy from below through processes that are still not well understood.

Until space observations became possible, we knew nothing about coronae in any other stars and had only marginal information about stellar chromospheres' properties. Now, space observations have shown us that a large fraction of the stars in the sky have chromospheres and coronae.

On several dozen stars, we have even detected activity that may be connected with sunspot (or “starspot”) cycles like those of our own Sun. X-ray telescopes carried on satellites have recorded flares in other stars that are far more powerful than the already impressive flares of the Sun. By observing the strength and frequency of these events on stars with masses, ages, and rotation rates which differ from those of the Sun, we search for answers to such basic questions as: “How does the sunspot cycle period depend on the star’s rotation rate?” or “What is the relation between the temperature of a star’s corona and the strength of its magnetic field?” By deciphering the general pattern of stellar properties, we can better understand what makes things happen on the Sun.

The Sun presents us with a bewildering variety of surface features, atmospheric structures, and active phenomena. Sunspots come and go. The entire Sun shakes and oscillates in several different ways at the same time. Great eruptions called prominences hang high above the Sun’s surface for weeks, suspended by magnetic force, and sometimes shoot abruptly into space from the corona. The explosions called solar flares emit vast amounts of radiation and atomic particles in short periods of time, often with little or no warning.

Space observations have discovered many new aspects of solar events hidden from ground-based observatories—the Sunshine's hottest spots primarily in ultraviolet and X-rays, rather than in visible light. Thus, only from space can we map high-temperature solar flares' true structure and determine their physical conditions. Space observatories have shown us the higher, hotter layers of the Sun’s atmosphere that normally are invisible from the ground. Instruments on satellites revealed that in flares and other violent disturbances, the Sun acts like an atomic accelerator, driving electrons and protons to velocities approaching the speed of light. At such high speeds, the particles emit the high-energy X-rays and gamma rays measured by our satellites. Sometimes they even induce nuclear reactions on the surface of the Sun.

Two aspects of our improved knowledge of the Sun deserve special attention. One is the role of magnetic fields in determining virtually all aspects of the Sun’s upper atmosphere's structure and behavior. The other is discovering the solar wind, a stream of atomic particles that constantly evaporate from the Sun’s atmosphere and are accelerated to speeds of hundreds of kilometers per second, escaping into space in all directions.

The Earth-Sun Battle

For any solar particle to reach the Earth, it must first pass through the Earth’s magnetic field. Before the solar wind was discovered, the Earth’s field was thought to be symmetrical, resembling a huge bar magnet, fading off indefinitely into space. However, we now know that the solar wind shapes the Earth’s magnetic field's outer regions and is sharply bounded. Outside the boundary, space is dominated by the solar wind and the interplanetary magnetic field. Inside the boundary is the region or magnetosphere dominated by the Earth’s magnetic field. The measurements from many space missions have been combined to reveal that the solar wind blows out the Earth’s magnetosphere into a teardrop shape. The head of the drop extends only about 10 Earth radii, or about 65,000 kilometers (40,000 miles) “upwind” toward the Sun. The tail of the drop stretches away in the direction opposite the Sun, actually reaching beyond the Moon’s orbit. This long magnetotail extends more than 600,000 kilometers (370,000 miles) from the Earth.

At the boundary of the magnetosphere, there is a constant struggle between the Earth's magnetic field and the forces of the Sun. Buffeted by fluctuations in the solar wind velocity and density, the magnetosphere’s size and shape are continuously changing. When the solar wind strikes the magnetosphere, shock waveforms are analogous to the sonic boom preceding a supersonic airplane. Inside the boundary with the solar wind, the magnetosphere remains an active region. It contains two belts of very energetic charged atomic particles trapped in the Earth’s magnetic field hundreds of miles above the atmosphere. These belts were discovered by Professor James Van Allen of the University of Iowa and his colleagues in 1958, using simple radiation detectors carried by Explorer 1, the first U.S. satellite.

The Northern and Southern Lights: Gifts from the Sun

The structure of the Earth’s magnetosphere also controls aurorae's behavior, seen in our night skies. Pre-Space Age textbooks stated that aurorae are produced by photons emitted from the Sun and reach the Earth’s upper atmosphere through gaps in the Earth’s magnetic field at the north and south magnetic poles. According to the theory, these protons strike oxygen atoms in the atmosphere, and the collisions cause the glow, which we call the Northern Lights.

This view has changed in the Space Age. The data collected by many spacecraft showed that the situation is more complicated. Particles from both the solar wind and from the Earth’s atmosphere apparently are stored in the magnetotail. From there, they periodically are violently ejected into the northern and southern polar regions of the atmosphere along the Earth’s magnetic field. They are accelerated to high speeds by a process not yet fully explained. The magnetotail is, in effect, a reservoir of particles that is periodically refilled. When the Sun is active during maximum sunspot years, this process is especially intense and frequent, and the aurorae are brighter and move closer to the equator.

Light Therapy — Wound Healing in Horses

LED light therapy is really a way to help the body heal itself. In Kaiyan, we have used specific wavelengths of light absorbed by a photo acceptor, cytochrome c oxidase, within the cell's mitochondria. The energy (photons) from the lights increases the energy within the cell, which speeds up the healing process. The lights must be specific wavelengths and must be delivered at a specific dosage. We use two wavelengths in our light therapy pads, a visible red and a near-infrared wavelength. Using both red and near-infrared lights is beneficial because different depths of tissue absorb the wavelengths. The combination of the two work in concert to provide benefits for soft tissue injuries, inflammation, ligament soreness, tendon problems, sore backs, splints, strains, stifle issues, sprains, swelling, shoulder pain, hip pain, sore backs, sore necks, salivary gland problems, wounds, cuts, scrapes, arthritis pain and for trigger points and acupuncture points. Visible red light (660nm) is absorbed by skin layers very efficiently and best for uses such as stimulating trigger and acupuncture points and treating wounds and infections. Near-infrared light (850nm) penetrates to a deeper level has been used to treat concerns of tendons, ligaments, bones, joints, and muscle.

When nursing skin wounds of horses, such as lacerations or deep abrasions, owners often seek ways to maximize healing and minimize scarring, particularly when high-motion areas are involved.

“In horses, dermal injuries can be slow to heal, cause excessive scarring, and prolong a horse’s layup. In some cases, especially wounds of the limbs, proud flesh may develop in response to exuberant healing efforts,”

Said Catherine Whitehouse, M.S., an advisor for Kentucky Equine Research.

Medical-grade honey, fly larvae, and other strategies have been tested to speed wound healing. Most recently, Swedish researchers explored the use of irradiation with light-emitting diodes (LEDs), called photobiomodulation, in jump-starting wound repair. The LED used in the study features a pulsating visible red light and near-infrared (NIR) light.

“Some research shows that LEDs stimulate wound healing and decrease swelling and inflammation. With this in mind, veterinarians were hopeful that low-level light treatment could expedite wound repair in horses,” Whitehouse explained.

In this study, researchers created two circular skin wounds on the necks of eight healthy horses. One wound was treated with a combination of red light and NIR light for 4 minutes and 40 seconds on specific treatment days during the 25-day study period. The other wound on each horse remained untreated. The researchers photographed and assessed the wounds for the degree of swelling using ultrasound.

Area and degree of swelling did not differ between treated and untreated wounds, prompting researchers to conclude that red light and NIR light had no clinically relevant positive effect on horses' wound healing.

A veterinarian should examine all significant wounds. Extensive wounds with significant blood loss or tissue damage should be considered medical emergencies.

*Michanek, P., T. Toth, E. Bergström, H. Treffenberg-Pettersson, and A. Bergh. 2020. Effect of infrared and red monochromatic light on equine wound healing. Equine Veterinary Journal. doi:10.1111/eve.13266.


Parkinson's: From the Gut to the Brain

Margaret Jarrett was diagnosed with Parkinson’s disease eight years ago. And although she was bothered by many of the symptoms that commonly afflict people living with Parkinson’s — resting tremor, uncertain gait, and terrible nightmares — the thing that bothered her the most was the loss of her sense of smell. An avid gardener, she took great pride in her roses but being unable to inhale their perfumed scent really got her down.

“You take something like your sense of smell for granted,” Jarrett, 72, said. “You don’t realize how precious something is until it’s gone.”

Parkinson’s disease combines movement disorders, including resting tremors, muscle rigidity, impaired balance, and movement slowness. It can also cause neurological problems such as depression, insomnia, memory loss, and confusion.

Its cause is unknown, but it is associated with dopamine depletion and destruction of neurons in the brain's basal ganglia region.

The current mainstay of treatment for Parkinson’s disease involves physical therapy and medications that act to increase dopamine levels in the brain. One relatively new therapy for Parkinson’s is exposure to infrared light.

Dr. Ann Liebert, co-ordinator of photomolecular research at the Australasian Research Institute, has been exploring the idea of using infrared light to modulate the gastrointestinal tract’s microbiome in humans.

The gut’s microbiome — composing trillions of bacteria, fungi, and protozoa from hundreds of different species that normally inhabit our gastrointestinal tract — has come under increasing scientific attention over the past decade, with links being established between the microbiome and several conditions including obesity, type 2 diabetes, cardiovascular disease, and depression. Several studies have also observed that the gut microbiome is markedly altered in patients with Parkinson’s disease. Fecal microbiota transplantation can have a protective effect in animal models of Parkinson’s.

The reason for this is unknown. However, an interesting observation is that another common pathology seen in Parkinson’s disease is the accumulation of misfolded proteins, called Lewy bodies, in the brain. It has been shown that certain sensory cells of the gut contain these same proteins.

Researchers have hypothesized that abnormal forms of the protein could travel from the gut to the brain through the vagus nerve, a phenomenon observed in animal models of Parkinson’s. Further support for this theory comes from findings that people who have had a surgical vagotomy — where branches of the nerve are cut — have a lower lifetime risk of developing Parkinson’s.

“We know that infrared light can reduce Parkinson’s symptoms and offer protection to brain cells. So, we wanted to test if it could modulate the gut’s microbiome as well,” Liebert said.

Provisional results from the first half dozen Adelaide participants, including Margaret Jarrett, have been promising.

“The six patients . . . showed an increase by up to 20 percent in the favorable microbiome that is associated with obesity reduction and short-chain fatty acid production. And the bacteria associated with rheumatoid arthritis, Crohn’s disease and insulin resistance were all decreased,” said Hosen Kiat, a professor of cardiology at Macquarie University, who oversaw the trial.

“For the last three years, I haven’t been able to smell flowers,” Jarrett said. “But several weeks into the trial, I started to smell my roses, daphnes, and gardenias again, and it was wonderful.”

Another participant, Barry Weldon, 70, had a similar experience. “My sense of smell improved significantly,” he said. “One day, I walked into the house, and for the first time in a long time, I could actually smell the soup my wife was cooking.”

Ron Till, 68, had an even more dramatic improvement. “The trial gave me the ability to sleep again,” he said. “It was amazing.”

Till’s neurologist cautioned him not to get his hopes up before the trial but changed his mind when he saw the results. “He told me it was voodoo medicine and probably wouldn’t work,” Till recalled. “But after the trial, I went back for my three-monthly assessment with him, and he said to me, ‘You’re actually testing better than when you first started with me ten years ago.’”

Retired geologist Sean Kennedy, 76, also experienced an improvement in his coordination and balance. “My juggling skills have improved,” he said.

In a review published in Photobiomodulation, Photomedicine and Laser Surgery, Liebert and her co-authors acknowledge that while the exact mechanism by which light therapy alters the microbiome is unknown, there is definite potential in light therapy.

“The ability of PBM [light therapy] to influence the microbiome (if proven to apply to humans) will allow an additional therapeutic route to target multiple diseases, including cardiovascular disease and Parkinson’s disease, many of which have thus far eluded effective treatment approaches,” the paper concludes.

Kiat is excited by light therapy’s potential. “If we can create non-­invasively a metabolically healthier microbiome through this extremely cheap and easy way, then inflammatory diseases and neurodegenerative diseases should be positively influenced,” he said.

Gold Coast-based GP Mark Jeffery is a clinician who has been using lasers in his practice for more than four years. He says the research supports the use of light therapy for a wide range of diseases, including Parkinson’s, Alzheimer’s, depression, and chronic pain.

“The reality is there are no real side effects from low-level laser therapy, and it’s one of the safest treatments you can ever do,” he says.

Liebert says the promising results they have seen thus far will inform a large, double-blinded randomized control trial planned for this year. “It has the potential to apply to huge fields of medicine,” she said.

Weldon’s neurologist, Chris Kneebone, is keeping an open mind on infrared light therapy’s potential. “We all just have to wait and see what the trial results tell us,” he said.

His advice for people who wish to give it a try for their Parkinson’s? “If you want to give it a go, give it a go,” he said. “I’ve got no reason not to recommend it, but at this stage, I’ve got no reason to think it is helpful either.”

As for Jarrett, she has no doubts that infrared light therapy has helped her. She enjoys pottering around in her garden again and has more energy than she has had for a long time.

“I feel like I could take on the world again,” she said. “My garden has never looked better.”

References

https://pubmed.ncbi.nlm.nih.gov/30074108/

https://pubmed.ncbi.nlm.nih.gov/29247431/

Fetuses May be Able to See More Light than you Think

By the second trimester, long before a baby's eyes can see images, they can detect light.

But the light-sensitive cells in the developing retina -- the thin sheet of brain-like tissue at the back of the eye -- were thought to be simple on-off switches, presumably there to set up the 24-hour, day-night rhythms parents hope their baby will follow. University of California, Berkeley, scientists have now found evidence that these simple cells actually talk to one another as part of an interconnected network that gives the retina more light sensitivity than once thought, and that may enhance the influence of light on behavior and brain development in unsuspected ways.

In the developing eye, perhaps 3% of ganglion cells -- the retina cells that send messages through the optic nerve into the brain -- are sensitive to light. To date, researchers have found about six different subtypes that communicate with various places in the brain. Some talk to the suprachiasmatic nucleus to tune our internal clock to the day-night cycle. Others send signals to the area that makes our pupils constrict in bright light.

But others connect to surprising areas: the perihabenula, which regulates mood, and the amygdala, which deals with emotions.

Recent evidence suggests that in mice and monkeys, these ganglion cells also talk with one another through electrical connections called gap junctions, implying much more complexity in immature rodent and primate eyes than imagined.

"Given the variety of these ganglion cells and that they project to many different parts of the brain, it makes me wonder whether they play a role in how the retina connects up to the brain," said Marla Feller, a UC Berkeley professor of molecular and cell biology and senior author of a paper that appeared this month in the journal Current Biology. "Maybe not for visual circuits, but non-vision behaviors. Not only the pupillary light reflex and circadian rhythms, but possibly explaining problems like light-induced migraines, or why light therapy works for depression."

Parallel systems in developing retina

The cells, called intrinsically photosensitive retinal ganglion cells (ipRGCs), were discovered only 10 years ago, surprising those like Feller, who studied the developing retina for nearly 20 years. She played a major role, along with her mentor, Carla Shatz of Stanford University, in showing that spontaneous electrical activity in the eye during development -- so-called retinal waves -- is critical for setting up the correct brain networks to process images later on.

Hence her interest in the ipRGCs seemed to function in parallel with spontaneous retinal waves in the developing retina.

We thought they (mouse pups and the human fetus) were blind at this point in development. We thought that the ganglion cells were there in the developing eye, that they are connected to the brain, but that they were not really connected to much of the rest of the retina, at that point. Now, it turns out they are connected to each other, which was a surprising thing."

Marla Feller, the Paul Licht Distinguished Professor in Biological Sciences and a member of UC Berkeley's Helen Wills Neuroscience Institute.

UC Berkeley graduate student Franklin Caval-Holme combined two-photon calcium imaging, whole-cell electrical recording, pharmacology, and anatomical techniques to show that the six types of ipRGCs in the newborn mouse retina link up electrically, via gap junctions, to form a retinal network that the researchers found not only detect light but respond to the intensity of the light, which can vary nearly a billionfold.

Gap junction circuits were critical for light sensitivity in some ipRGC subtypes. Still, not others, providing a potential avenue to determine which ipRGC subtypes provide the signal for specific non-visual behaviors that light evokes.

"Aversion to light, which pups develop very early, is intensity-dependent," suggesting that these neural circuits could be involved in light-aversion behavior, Caval-Holme said. "We don't know which of these ipRGC subtypes in the neonatal retina actually contributes to the behavior, so it will be fascinating to see what role all these different subtypes have."

The researchers also found evidence that the circuit tunes itself in a way that could adapt to the intensity of light, which probably has an important role in development, Feller said.

"In the past, people demonstrated that these light-sensitive cells are important for things like the development of the blood vessels in the retina and light entrainment of circadian rhythms, but those were kind of a light on/light of the response, where you need some light or no light," she said. "This seems to argue that they are actually trying to code for many different intensities of light, encoding much more information than people had previously thought."
Source:

University of California, Berkeley

Journal reference:

Caval-Holme, F., et al. (2019) Gap Junction Coupling Shapes the Encoding of Light in the Developing Retina. Current Biology. doi.org/10.1016/j.cub.2019.10.025.


Light Therapy can Benefit Patients with TBI (Traumatic Brain Injury)

According to a pioneering study by researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH), light therapy is safe and has measurable effects on the brain.

Senior investigators Rajiv Gupta, MD, Ph.D., director of the Ultra-High Resolution Volume CT Lab at MGH and Benjamin Vakoc, Ph.D., at the Wellman Center led the study, which was supported by a grant from the Department of Defense (DOD) and published in JAMA Network Open September 14th.

This study is one of the first, if not the first, prospective, randomized, interventional clinical trials of near-infrared, low-level light therapy (LLLT) in patients who recently suffered a moderate brain injury. If further trials support these findings, light therapy could become the first widely-accepted treatment for this type of injury.

TBI is the leading cause of traumatic injury worldwide, and an estimated 69 million people experience such an injury every year. However, there are no treatments for this condition yet, largely because the underlying biological mechanisms are not well understood. It is so challenging to do studies with actual patients in the acute stage of trauma.

"The Gulf War put TBI in the headlines because body armor had been greatly improved by then. But there were still brain injuries caused by the shock waves from high powered explosives.”

Rajiv Gupta, MD, PhD, Director, Ultra-High Resolution Volume CT Lab

For various reasons, the number of TBIs has increased around the globe since then, but effective treatments are still sorely needed. For this study, a special helmet had to be designed specifically to deliver the therapy, an undertaking that required a mix of medical, engineering, and physics expertise.

This multidisciplinary team included Gupta, a neuroradiologist, Vakoc, an applied physicist, and others specializing in developing and translating optical instrumentation to the clinic and biologic laboratories. Both Gupta and Vakoc are also associate professors at Harvard Medical School.

“For this study, we designed a practical, near-infrared treatment based on Wellman Center research and working directly with DOD on the vexing problem of TBI, a condition faced by so many,” says Rox Anderson, MD, the center’s director.

Another challenge was optimizing the wavelength of the near-infrared LLLT.

“Nobody knows how much light you need to get the optimal effect,”

explains Lynn Drake, MD, one of the study co-authors and director of business development at the Wellman Center.

“We tried to optimize the wavelength, dosing, timing of delivery, and length of exposure.”

This was done through a series of pre-clinical experiments led by Anderson. These included multiple preclinical studies led by Michael Hamblin, Ph.D. Anderson and Hamblin are both co-authors of this paper.

Near-infrared LLLT has already been considered for multiple uses, but to date, few if any studies of this technology have been tested and none in patients with TBI.

It has been studied in stroke patients, and Wellman's basic laboratory research suggests it is neuroprotective through a mechanism mediated by specialized intracellular organs called mitochondria. It took several years of research at Wellman to understand the basic mechanism before the clinical trial.

The randomized clinical trial included 68 patients with moderate traumatic brain injury who were divided into two groups. One group received LLLT via the special helmet, which delivered the light. Patients in the control group wore the helmet for the same amount of time but did not receive the treatment.

Vakoc’s team at Wellman designed the helmet. During the study, the subjects’ brains were tested for neuron activity using quantitative magnetic resonance imaging (MRI) metrics, and the subjects also underwent neurocognitive function assessment.

MRI was performed in the acute (within 72 hours of the injury), early subacute (2–3 weeks), and late subacute (approximately three months) stages of recovery. During each visit and at six months, clinical assessments were performed using the Rivermead Post-Concussion Questionnaire, with each item assessed on a five-point scale.

Twenty-eight patients completed at least one LLLT session, and none reported any adverse reactions. Also, the researchers found that they could measure the effects of transcranial LLLT on the brain.

The MRI studies showed statistically significant differences in myelin's integrity surrounding the neurons of treated patients versus the control group. Both these findings support follow-up trials, especially since there are no other treatments for these patients.

The study also showed that light does impact the cells. While it is well established that cells have light receptors, “going into this trial, we had several unanswered questions such as whether the light would go through the scalp and skull, whether the dose was sufficient, and whether it would be enough to engage the neural substrates responsible for repair after TBI,” says Gupta.

It’s important to note, and he adds that for this initial study, the researchers focused on patients with moderate traumatic brain injury. That helped ensure their study could have statistically significant findings because patients in this category are more likely to demonstrate a measurable effect.

“It would be much more difficult to see such changes in patients with mild injuries, and it is quite likely that in patients with severe brain injuries, the effect of light therapy would be confounded by other comorbidities of severe trauma,”

says Gupta.

He adds that researchers are still very early in the development of this therapy. It is unknown if it could be applied to other types of brain injury, such as chronic traumatic encephalopathy (CTE), which has received a lot of public attention over the last few years.

CTE is a progressive degenerative disease associated with a history of repetitive brain trauma such as that experienced by certain athletes, most notably football players.

This study opens up many possibilities for the broader use of photomedicine. “Transcranial LED therapy is a promising area of research, with potential to help various brain disorders where therapies are limited,” says Margaret Naeser, Ph.D., a prominent researcher in photomedicine and research professor of Neurology at Boston University School of Medicine. She was not affiliated with this particular study.

Source:

Massachusetts General Hospital

Journal reference:

Longo, M, G. F., et al. (2020) Effect of Transcranial Low-Level Light Therapy vs. Sham Therapy Among Patients With Moderate Traumatic Brain Injury. doi.org/10.1001/jamanetworkopen.2020.17337.

How Effective is Blue Light Therapy for Spider Veins?

Medical spas often recommend Blue light therapy for spider veins because they don’t have to be administered by trained doctors. And, yes, after several expensive sessions, you might start seeing a difference. The most effective method to treat spider veins is Sclerotherapy. We’ll also discuss the benefits of using Sclerotherapy is an effective alternative.

What are Spider Veins?

Before discussing how to treat spider veins with blue light therapy or sclerotherapy, we need to discuss what causes spider veins.

Spider Veins, scientifically called Telangiectasias, are a small network of blood vessels visible just under the skin's surface. They are called “spider veins” because they look like red spider webs.

Spider veins generally occur on the legs, feet, thighs, and face. They can also cause slight pain and discomfort.

Causes and Dangers of Spider Veins

While spider veins aren’t dangerous in and of themselves, they can indicate underlying vein disease.

Vein Disease, also known as Chronic Venous Insufficiency, is a disease in which the valves in the veins malfunction. The valves are usually supposed to act as one-way doors and facilitate blood flow to the heart. However, when they malfunction, blood flows back down and pools around the legs. This can put pressure on the veins and lead to spider veins or varicose veins.

While spider veins themselves aren’t dangerous, vein disease is hazardous and needs to be treated immediately. If left untreated, venous insufficiency can result in bleeding, skin infections, and ulcers.

In the worst-case scenario, vein disease can also lead to Deep Vein Thrombosis, a medical condition in which blood clots in the veins. If the clotted blood breaks, it can get carried to the lungs, leading to a potentially fatal condition called Pulmonary Embolism.

What is Blue Light Therapy for Spider Veins?

Blue Light Therapy for spider veins is a method in which blue light or laser is used to treat spider veins. The laser is non-UV in nature and emits photons that generate heat. The heat can destroy the damaged blood vessel over time. As such, the damaged vein shrinks and eventually dissolves.

Advantages of Blue Light Therapy for Spider Veins

The only time that blue light therapy for spider veins has an advantage over sclerotherapy is when it comes to the foot or face.

Both the face and the foot are dense with venous-arterial connections. When using Sclerotherapy, the Sclero has to be injected into the veins. Injecting it into the arteries can be dangerous. Most conservative physicians prefer not to use Sclerotherapy for spider veins in the face or foot.

As such, it’s better to go for blue light therapy for spider veins in the face or foot.

Sclerotherapy: An Alternative to Blue Light Therapy for Spider Veins

Sclerotherapy is the most effective and permanent method to treat spider veins. It is a minimally-invasive procedure in which a medicine called Sclerosant is injected into the damaged vein.

The Sclerosant inflicts some chemical damage to the veins, which leads to the vein walls sticking together and eventually closing up. The blood is then routed to healthier veins, and the damaged vein eventually gets reabsorbed.

Advantages of Sclerotherapy for Spider Veins

There are multiple advantages of using Sclerotherapy to treat spider veins:

  • The process is minimally-invasive and non-surgical in nature.
  • Sclerotherapy doesn’t hurt or cause much discomfort.
  • It works immediately, and you don’t need to come back for multiple treatment sessions.
  • It can get rid of spider veins permanently.
  • The entire process takes just about 30 minutes.
  • You can resume your daily activities immediately after.
  • It is cheaper than Blue Light Therapy.


Red Light Therapy Can Help Reduce Inflammation

We can usually identify inflammation when we see it. The inflamed part of the body looks red and swollen, and it feels hot and painful. But in this article, we’ll find out why we experience inflammation, as well as its causes, risk factors, and how red light therapy devices can help reduce it.

What Really is Inflammation?

Inflammation is our body’s natural response to pain, irritation, damaged cells, exposure to germs, and potential danger. There are two types of inflammation:

1. Acute inflammation

This type of inflammation happens as our body’s healthy response to injury or stress. We mean “healthy” because it helps the body recover faster. The inflammation happens only for a few hours and then starts to repair the damaged tissue.

2. Chronic inflammation

On the other hand, chronic inflammation can be excruciating and may cause discomfort or inconvenience. It causes an imbalance in the body, making it operate inefficiently over time. Chronic inflammation can be caused by viral infections, repetitive tissue damage, autoimmune reactions, and persistent and recurring acute inflammation. At its worse, this type of inflammation may lead to more serious diseases and/or conditions such as cancer, stroke, depression, and heart disorder.

Common Causes of Inflammation

Anything that causes stress on your body may lead to inflammation. These include:

  • Bruises
  • Bumps
  • Burns
  • Chemical irritants
  • Dehydration
  • Diseases
  • Excessive alcohol
  • Infection
  • Irritants
  • Poor nutrition
  • Poor sleep
  • Splinters
  • Toxin exposure
  • Wounds and injuries

Signs of Inflammation

There are five common signs of inflammation:

  • Heat on the inflamed area
  • Loss of function (i.e., you can’t move your arms or legs)
  • Pain
  • Redness
  • Swelling
Treatment Options for Inflammation

For acute inflammation, doctors normally recommend nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and paracetamol. Meanwhile, chronic inflammation may also be prescribed with NSAIDs, along with steroids and supplements.

However, these common treatment options help prevent inflammation symptoms but do not deal with the root cause, including improper cellular function, biological imbalance, and damaged tissues. This is also why lifestyle changes (improved diet, regular exercises, and high-quality sleep) and red light therapy could be of great help.

How Red Light Therapy Works Against Inflammation

Red light therapy, also referred to as low-level laser therapy (LLLT) or photobiomodulation (PBM), is a non-invasive treatment option. This kind of therapy delivers wavelengths of red and near-infrared (NIR) light to your skin and cells for multiple benefits. When it comes to inflammation, it can help cut down oxidative stress and activate protective cellular mechanisms to boost your immune system and protect you from diseases that may cause inflammation. It can also boost the generation of healing agents and antioxidants in the body to speed up damaged tissues' healing process.

Red light therapy can give your body the light exposure needed to function more efficiently, improve blood flow, and limit inflammation.

Conclusion

Inflammation is a natural part of our biological processes, but chronic cases may also lead to serious health risks that can affect the quality of your life. Therefore, if you’re experiencing signs of inflammation, regardless if it’s acute or chronic, please schedule an appointment with your doctor to get the care and treatment you need as early as possible.

In the meantime, to protect your body from the stress that may cause inflammation, you can do red light therapy either through a health provider or from the comfort of your home. If you need to purchase red light therapy devices, you can browse through our catalog to see the brands and products that we offer.


Keep Your Skin Healthy with Red Light Therapy

Skincare doesn’t just affect the way you look. It also plays a huge role in your overall health — from body temperature to hormone regulation to your immune system. If you’re into skincare as much as we are, one of the many ways that can help you keep your skin healthy is red light therapy. In this article, we’ll take a deep dive into why you should take care of your skin, and we’ll also discuss how red light therapy devices can help you achieve your skin goals.

Are you ready? Let’s go straight into it.

Why Do You Need to Take Care of Your Skin?

As the largest organ in our body, your skin is your body’s first defense line to bacteria, germs, viruses, etc. It’s a vital part of the immune system and some processes in your body, such as temperature control, blood circulation, and hormone production.

Main Functions of the Skin

Let’s take a look at the skin's main functions to help you understand how essential it is for you to take care of this vital organ.

1. Defense and Immunity

The skin is an active immune organ, and it serves as our physical barrier from the dangers of the environment. It helps protect our bodies from diseases, germs, viruses, dirt, UV radiation, and potential thermal and physical injuries. It also helps detect and fight off infection, toxins, allergens, hazardous substances, and carcinogens.

2. Temperature Regulation

Aside from protecting us from extreme cold or heat, the skin also helps prevent moisture loss, keeping us from being dehydrated.

3. Sense of touch

The skin has a somatosensory system that is composed of touch receptors and nerve endings. This system is responsible for the sensations we feel, including pain, pressure, vibrations, smoothness, roughness, heat, cold, tickle, itch, and more.

4. Storage and Production of Vitamin D

Your body also uses your skin's deeper layers to store metabolic products, fat, and water. The skin is also responsible for producing vitamin D, supplied in the body when the skin gets enough sunlight exposure.

5. Beauty

Need we say more? Your skin plays a huge part in your appearance. Of course, when your skin is healthy, you also look glowing, radiant, and definitely more attractive.

Red Light Therapy and Keeping Your Skin Healthy

Before we proceed with the “how,” let’s first define what red light therapy is. Red light therapy is a non-invasive treatment option for different kinds of medical conditions. It is also used for health improvement and various aesthetic procedures.

Decades ago, red light therapy machines were only available in clinics, high-end salons, and spas. Nowadays, red light therapy devices can be bought and used by anyone. In fact, you can do red light therapy at the comfort of your home and incorporate it into your skincare routine.

How Does Red Light Therapy Work?

Red light therapy works by delivering wavelengths of red and near-infrared (NIR) light to our cells and skin. Besides helping enhance cellular function, red light therapy also helps stimulate the mitochondria and produce ATP (adenosine triphosphate) energy. This treatment option usually takes only about 10 minutes per session.

How Does Red Light Therapy Help Keep Your Skin Healthy?

Our skin relies on millions of cells to be able to perform its functions. When our cells experience homeostasis or a state of balance, our skin and body perform (and look) better. And as mentioned above, red and NIR light enhances cellular function while also preventing inflammation and oxidative stress. Red light therapy helps make your skin look and feel softer, smoother, and healthier.

Besides, red light therapy also helps damaged tissues heal and regenerate faster. It also has anti-inflammatory benefits, potentially increasing blood flow to damaged and inflamed tissues and reducing oxidative stress.

Final Thoughts

Skincare is self-care, as keeping your skin healthy also produces multiple benefits to your health. Thankfully, aside from proper hygiene, regular exercise, a balanced diet, and an established skincare routine, red light therapy can also improve your overall skin health.

For more information about red light therapy or to view our catalog of red therapy devices, click here.

Sources:

https://www.hse.gov.uk/skin/professional/causes/structure.htm

Improving Mental Acuity with Light Therapy

It’s common knowledge that as we age, our normal brain function gets disrupted. We tend to find it harder to recall information, memorize names, and respond with reason. The decline of our mental acuity causes these commonplace mental problems. Contrary to popular belief, aging is not the sole culprit for mental deterioration. Many factors, such as aging, lifestyle changes, and environmental stress, contribute to the decline of mental acuity.

As cognitive decline progresses, significant mental changes can result in disorders such as dementia, Alzheimer’s disease, and Parkinson’s disease. While these can be common aspects of life, they aren’t inevitable. Many medical experts believe that there are many lifestyle changes that you can take to prevent the degradation of Mental Acuity.

What is Mental Acuity?

Mental acuity is known as the sharpness of the mind. It involves our cognitive ability to concentrate, process, understand, reason, and memorize. On the other hand, intelligence means the extent to which our brains absorb and process a specific amount of information at a given amount of time. Mental acuity is a natural and essential aspect of our brain health and is not a measure of how “smart” we are.

Mental acuity allows us to perform daily activities effectively and efficiently. When our cognitive ability functions well, we’re more capable of doing things without damage or conflict.

What are the symptoms of a Deteriorating Mental Acuity?

Some signs of a deteriorating cognitive ability may be subtle. However, when left untreated could progress over time to more serious mental disorders. According to the National Institute on Aging, 8 out of 10 people who experience amnestic mild cognitive impairment develop into having Alzheimer’s disease.

Here are some early symptoms of a deteriorating mental acuity:

  • Absent-mindedness and having trouble concentrating
  • Forgetfulness of specific details like names, dates, events, and facts
  • Inability to reason and make vital decisions
  • Difficulty in retrieving information
  • Memory loss
  • Difficulty in following simple instructions

How to Improve Mental Acuity

Prevention is better than cure when it comes to developing chronic brain disorders. Here’s how you can take your brain health into your own hands by observing these lifestyle habits:

  1. Ensure a well-balanced diet

Getting enough nutrition is the key to ensure mental sharpness. Making sure you eat a well-balanced diet can help your body supply enough nutrients to your brain. Omega 3 Fatty Acids are essential nutrients that help build and restore brain cells. The brain also needs antioxidants to prevent inflammation.

Excessive intake of toxins such as alcohol and drug can depreciate your mental ability. Experts agree that poor gut health also results in a weakened immune system. As a result, it weakens your body’s inflammatory response. A poor inflammatory response causes mental disorders such as schizophrenia and dementia.

  1. Have Enough Sleep

Irregular sleep patterns and sleep deprivation disrupt your body’s circadian rhythm that can lead to short-term mental problems as well as long-term chronic health problems.

Your body’s circadian rhythm is a natural body clock that controls your sleep-wake schedule as well as your digestive patterns. When you’re sleep-deprived, these rhythms get disturbed. As a result, you experience headaches, mood swings, and difficulty to focus and recall information. Aside from these unwanted effects, not having enough sleep also negatively impacts your overall brain health.

  1. Get Yourself Moving

Exercise isn’t just for physical and aesthetic purposes. It also affects brain function in multiple ways. When you exercise, your body pumps more oxygen into your brain through an increased heart rate. Exercise allows your body to release hormones that are vital in nourishing your brain cells. It also promotes growth factors in your brain to assist in the growth of neuronal connections.

A study at the University of Georgia shows that a 20-minute exercise daily can improve memory retention and information processing. Many experts agree that a sedentary lifestyle may accelerate your way into cognitive decline.

  1. Use Red Light Therapy

Red Light therapy is a more modern approach to non-invasive and low-risk medical treatments. It is a form of photobiomodulation that allows light to change human cells' physiology that causes a wide range of benefits such as biological balance and cellular energy.

Kaiyan Medical is one of the pioneers of Red light therapy that uses red wavelengths to deliver benefits to the skin and near-infrared lights to penetrate deeper within the skin’s surface. This dual technology allows for better absorption and effectiveness of the benefits of Red light therapy.

As near-infrared wavelengths penetrate the brain’s cellular system, it promotes energy production by stimulating the mitochondria. It also prevents stress by keeping away oxidative stress. Thus, it delivers multiple benefits such as better blood flow, faster cell regeneration, and improved healing.

A study shows that red light therapy has significantly improved brain function when given to patients with cognitive dysfunction. All these benefits are vital in promoting and maintaining a healthy mental acuity. Red light therapy delivers all these cellular benefits to promote better sleep quality and a more balanced circadian clock.

As you maintain these lifestyle changes, you can experience a more improved brain function and better brain health. Now you can defy all odds and allow your brain to perform at its peak by having a healthy lifestyle and a balanced body.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043367/

https://www.medicalnewstoday.com/articles/324044#oily-fish

https://pubmed.ncbi.nlm.nih.gov/12595152/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403829/

https://www.healthline.com/health/mental-health/brain-exercises

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870908/


Animal Wellness: Red Light Therapy for Dogs

Certified pup parents know pets could easily sense when we’re feeling sad, happy, scared, or sick. Our furry friends could probably read us better than we could read them. However, active pets are also prone to injuries, cuts, wounds, inflammation, and infections like human beings.

If you’re a pet owner, you’d always want to give your pets the best care possible to make sure they are healthy and happy at all times. Thankfully, medicine has innovated well enough to find more advanced treatments and maintenance tools for our canine friends. In recent years, pet owners and some veterinarians have been using safe, non-invasive, and high-tech treatments for pets and domestic animals such as Red-Light therapy.

What is Red Light Therapy?

Red light therapy has been utilized by the veterinary world to deliver similar benefits to pets, just like humans. Red light therapy is a non-invasive treatment and a form of photobiomodulation that alters animal cells' physiology.

Light therapy produces wavelengths of photons that the photoreceptors in the animal’s bodies can absorb. The light provides alteration to the animal cells that result in numerous benefits such as better blood circulation and natural cellular regeneration.

Multiple studies support the efficacy of red-light therapy to animals. A 2017 study shows how Red Light therapy promoted faster healing for dogs that underwent bone surgery. The findings were also complemented by another study that suggests near-infrared wavelengths promoted bone cell reproduction for dogs.

Red Light Treatment for Dogs?

When our pets sprain their ankles or cut their pads, their cells become damaged. As a result, their bodies need cell energy in the form of adenosine triphosphate (ATP) to repair damaged cells and tissues.

The photoreceptors in their body absorb red light. The light stimulates ATP production in the animal’s body that results in faster delivery of nutrients and better excretion of toxins. All of these processes are essential for the body’s healing.

Red Light also promotes better circulation as it stimulates Nitric Oxide production to help blood vessels remain flexible. Injured or damaged cells need proper blood flow for healing. Light therapy helps in the healing process by increasing blood flow to ensure enough nutrients and oxygen in the affected area.

Red light is beneficial for surface healing by helping tissues that are potent in hemoglobin. On the other hand, near-infrared light can work better on deeper wounds as it can pass through the animal’s body's deeper tissues.

Innovators like Kaiyan Medical uses the FDA-cleared Red Light Therapy pad that utilizes the combined technology of Red Light-emitting diodes that can penetrate the skin and infrared wavelengths that can heal muscles, ligaments, and tendons. Red light and near-infrared wavelengths are the ideal combination of surface and inner healing.

Aside from providing the cells with energy, the light also stimulates collagen production, which aids in repairing damaged tissues. Collagen is an essential protein that can help get rid of scars and wounds.

What are the conditions that can be addressed by Red Light Therapy?

Skin and Surface issues

  • Surface wounds
  • Hair loss
  • Eczema
  • Other Skin Conditions
  • Wounds and Cuts

Deeper surface issues

  • Arthritis
  • Soft tissue injuries
  • Ligament injuries
  • Post-surgery Inflammation
  • Pain, Inflammation, and Swelling
  • hip dysplasia
  • Tendon problems
  • Strains and sprains
  • Salivary gland problems

General Maintenance

  • Maintenance of healthy joints and Bones
  • Maintenance of healthy Cardiovascular system
  • Maintenance of healthy Digestive system
  • Healthy Vision
  • Prevention of anxiety

Light therapy can be your best therapeutic tool in boosting your pet’s overall wellbeing. As a general rule, light therapy is a safe and non-invasive option for treating minor issues and maintaining their overall health. However, if your pet is undergoing more severe health problems, it’s best to consult your veterinarian for a more conducive treatment plan. While red light therapy is not a panacea for all your dog’s health issues, it’s a low-risk and pain-free option to complement treatments and to promote overall wellness for your beloved pet.

References:

https://www.jstage.jst.go.jp/article/islsm/13/1/13_1_73/_article/-char/ja/

https://onlinelibrary.wiley.com/doi/full/10.1111/vde.12170?deniedAccessCustomisedMessage=&userIsAuthenticated=false

https://www.thieme-connect.com/products/ejournals/abstract/10.3415/VCOT-15-12-0198

https://www.degruyter.com/view/journals/plm/1/2/article-p117.xml

https://onlinelibrary.wiley.com/doi/abs/10.1053/jvet.1999.0292?deniedAccessCustomisedMessage=&userIsAuthenticated=false

Answering FAQs About Hyperpigmentation

You might have heard about hyperpigmentation from your dermatologist or a skincare company. But if you didn’t completely understand this skin condition — and you want to know how it develops, how to remove it, etc. — or if you have questions about this skin condition, this article can be of help.

What is Hyperpigmentation?

Hyperpigmentation can be one or multiple skin patches or spots that appear much darker than your skin color. It is a cell mutation caused by changes in hormones, an injury like sunburn, acne, peeling from chemicals or any treatments, or inflammation. The darker areas of hyperpigmentation are excess deposits of melanin. And although it is harmless and common, having hyperpigmentation can make people more conscious about their looks. In fact, some people try to conceal it with cosmetic products, while some try to deal with it with professional help.

What are the Common Causes of Hyperpigmentation?

Age spots: As we age, brown, black or tan skin spots may develop on our hands, face, and/or head. These mostly affect light-skinned individuals and are caused by too much exposure from the sun.

Melasma: Usually caused by hormonal changes, melasma is common in women, especially those who are pregnant. It is composed of large patches of darkened skin that can appear on the face or stomach. Those with darker skin are more likely to have melasma.

Inflammation: This is caused by autoimmune reactions from skin conditions like acne and eczema or a skin injury. Post-inflammatory hyperpigmentation appears on the face and neck, and its appearance may vary depending on the skin tone. Inflammation can happen to anyone, regardless of skin color and origin.

How Can I Treat Hyperpigmentation?

There are different treatment options for hyperpigmentation, depending on your skin tone. Fair skin can be treated by most hyperpigmentation procedures, such as laser treatments and micro peeling. Medium skin usually reacts better with chemical peels and microdermabrasion therapy. Darker skin can benefit from using glycolic acid, kojic acid, microdermabrasion in a low setting, lower-strength chemical peels, and low-intensity laser treatments.

Some important things to watch out for when treating hyperpigmentation include:

  • Take a lot of vitamin C, an antioxidant that helps fight dark spots. Vitamin C helps prevent melanin production by inhibiting tyrosinase enzymes, causing lighten pigmentation and making normal skin brighter.
  • Another way to treat hyperpigmentation is to re-injure the skin's affected area, flushing the pigment to the surface.
  • There are topical creams or even home remedies (i.e., aloe vera, green tea, and licorice) that can be used to help heal hyperpigmentation. Some people find them effective, while others find other treatments with the same purpose as these treatments more effective. Red light therapy is one example.
  • Dark skin should be treated more carefully to prevent hypopigmentation, development of white spots that cannot be reversed.
Is Light Therapy Effective in Treating hyperpigmentation?

Photobiomodulation is another name for red light therapy. It may help the body produce more energy and regenerate the skin by using natural light. This can also be used on hyperpigmentation and other skin injuries like acne, inflammation, burns, and scars. When used consistently, light therapy is highly effective in reducing and healing hyperpigmentation patches and helping them return to normal pigment levels.

Red light therapy is a powerful, advanced relief for skin inflammation. Skin cells heal and rejuvenate better when exposed to healthy wavelengths of light, which can help treat hyperpigmentation.

Why is Red Light Therapy Better than Near-infrared Light Therapy in Treating Hyperpigmentation?

There’s a study that shows near-infrared light can help produce tyrosinase enzyme, which prevents melanin production. This helps patients with vitiligo stimulate melanocytes, the same compound in vitamin C that helps lighten hyperpigmentation. But the truth is, there is no clear clinical consensus among photomedicine researches about using near-infrared light for hyperpigmentation.

Red light wavelengths are considered to be safe as it does not stimulate the production of pigment. It creates healthy wavelengths of light to help the skin cells heal and rejuvenate naturally.

When can Results be Seen After Doing Light Therapy to Treat Hyperpigmentation?

Results can be seen after several treatments done per week. The level of skin improvement depends on how consistently you use red light therapy. Also, the more consistent and the more careful you are in the process, the better the results you can see. Be sure not to pick or touch the treated areas to avoid infection or irritation.

Conclusion

Light therapy, especially when combined with other treatment options, can greatly help remove hyperpigmentation. To learn more benefits of red light therapy, you may reach out to us. We offer safe and easy-to-use light therapy devices that physicians use both for aesthetic and medical purposes. Meanwhile, if you have more questions about hyperpigmentation, please reach out to your dermatologist.

More References

https://www.aocd.org/page/Hyperpigmentation#

https://www.healthline.com/health/hyperpigmentation

https://www.healthline.com/health/beauty-skin-care/hyperpigmentation-treatment

https://theskincareedit.com/red-light-therapy-benefits#:~:text=Red%20Light%20

The Benefits of Red Light Therapy in Treating Hypothyroidism

Thyroid issues are a commonplace problem that affects all ages and genders. It significantly contributes to changes in mental outlook, energy levels, skin, and weight. Hypothyroidism has drawn much attention due to many cases that are left undiagnosed, untreated, or inadequately treated. As a result, it led to more serious problems such as infertility, heart disease, neurological problems, and high cholesterol and blood pressure levels. Not to mention, treatment studies for hypothyroidism have experienced a significant backlog throughout the years.

In this article, we take a look at the basic precepts of hypothyroidism and how Red light therapy plays a role in treating the thyroid problem.

What is Hypothyroidism?

Hypothyroidism is a chronic abnormality of the thyroid gland, demonstrating an inadequacy of thyroid hormones such as triiodothyronine and thyroxine (T4). Normal levels of thyroid hormones stimulate a healthy amount of mitochondrial energy production. This means that in hypothyroid cases, the thyroid inhibits a state of low cellular energy.

As a result, people who suffer from this chronic problem often feel unusual fatigue, tiredness, weight changes, and skin problems. However, symptoms can vary from person to person and may even be subtle enough to be left undiagnosed and untreated. When left untreated, the disease causes more irreversible neurological, reproductive, and cardiovascular problems. It’s also found that Hypothyroidism is found to be five to eight times more prevalent in women than in men.

What Causes Hypothyroidism?

Hypothyroidism can be caused by a wide range of diet and lifestyle issues. Some cases can be caused by a lack of iodine intake, especially in more underdeveloped parts of the world. It can also be caused by other dietary issues such as low carb intake, excess polyunsaturated fat intake, and alcoholism. Other typical causes include stress, aging, sleep deprivation, and heredity.

What is Light Therapy?

When talking about light, we often think of it as the first thing we switch on in a dark room or the bright rays that set up the mood. We don’t usually think of it as having bioactive properties, penetrating beneath our skin, affecting the way our hormones, tissues, and cells function.

In reality, our cells actually capture photons of light, just like how plants do. Light therapy, also called photobiomodulation, essentially means light (photo) changing (modulation) your biology (bio).

How Can Red Light Therapy Help Treat Hypothyroidism?

Red and near-infrared light therapy, backed by over 5,000 studies, has grown its significance in medicinal treatments throughout the years.

Red light therapy is significantly targeted for hypothyroidism because unlike other kinds of light; they have a greater penetrability beneath our skin.

In fact, a 2010 study found that 38% of patients with Hashimoto’s hypothyroidism who were given red light therapy treatments have reduced their medication dose, while 17% have been able to stop the medication completely.

Here’s how it works:

  1. It Supplies energy

Because hypothyroidism is reflective of low cellular energy in the thyroid, red and near-infrared light helps the cells work better by supplying more energy to your body.

They have a photoreceptor called cytochrome c oxidase that works by catching photos of light. Like how our food is being processed by our body for the mitochondria to stimulate energy, the photos of light also stimulate energy production in the mitochondria. The mitochondria are responsible for the energy production of our body’s cells.

  1. It Prevents Stress

Red light is also shown to prevent stress by averting nitrous oxide poisoning. This means that aside from helping the mitochondria supply more energy, red light helps the thyroid hormone by alleviating stress-related molecules' effects.

  1. It Breaks the Cycle

Hypothyroidism is a vicious cycle of having low energy availability and decreased thyroid hormone production. By stimulating energy production in the mitochondria and preventing nitrous oxide poisoning prevention, red light can potentially break the cycle responsible for hypothyroidism.

In Kaiyan Medical, we produce a medical-grade red light therapy device that is effective and non-invasive, ideal for supplementing hypothyroidism treatments. Our device has a dual optical energy technology that combines red light and infrared light therapy as an excellent spectrum for deeper penetration and absorption. You can now rise above hypothyroidism and maximize your body’s healing properties with our Red Light therapy device.

More References

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247385/

https://drruscio.com/red-light-therapy-part-ii/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822815/

https://www.health.harvard.edu/newsletter_article/treating-hypothyroidism


How Saunas and Red Light Therapy are Distinct but Complementing

Saunas and red light therapy devices are clinically-proven treatments that complement each other wonderfully, even if they depend on distinct biological mechanisms to yield various natural health and aesthetic benefits.

In this article, we’ll focus on how things work for red light therapy and the distinctions of traditional saunas, and what you can actually gain by availing of either of them.

What You Need to Know About Saunas

Saunas can make your body’s core temperature hotter by supplying sufficient heat throughout your body. It has been a part of traditional medicine for various centuries, as the old century folks realized the health benefits of sweating. Although there are multiple types of saunas, two of them are the most popular:

  1. Traditional Convection Saunas

When you think of saunas, this is the first scenario that comes to mind: hot and steamy. This type of sauna requires more energy as it delivers heat to the atmosphere, warming the air inside the sauna, and distributes heat in the body. Traditional convection saunas can maintain air temperatures between 170–200°F and are an ideal type of sauna for general use. It is important to comprehend the different temperatures required for specific health concerns since being exposed to heat more than what has required triggers a warning for unsubstantiated claims.

  1. Infrared Saunas

The latest trend in saunas is the infrared saunas. Inside, instead of warming the air, this kind of sauna heats actual objects. Such objects include those with emitting surfaces, charcoal, and carbon fiber. Infrared saunas' effectivity is directly attributed to the temperature, humidity, and length of time your body is exposed to heat, even though many saunas claim to provide “full-spectrum” infrared wavelengths.

The farther the wavelengths are in the infrared spectrum, the more they are considered efficient and effective in heat production. This will be thoroughly discussed later, but the general gist is that heat supplementation is the primary purpose of saunas, convection, and infrared.

On the other hand, near-infrared wavelengths in near-infrared saunas generate very little heat. Most of the high-quality standard saunas use more effective heats from the far-infrared spectrum or IR-C wavelengths.

What are the Health Benefits of Saunas?

Inducing thermal stress on the body is the primary function of every sauna, but what does it really mean?

One of many biological responses from sauna usage is increased heart rate as well as perspiration. The essential body processes protein metabolism and is also affected by enough heat. Heat shock proteins are a special kind of protein that responds specifically to cellular stress from heat. Heat stress induction leads to natural health benefits like those we gain doing physical activities.

One experiment had participants sat in a sauna treatment for 30 minutes at 194°F for 3 weeks, totaling 13 work sessions. The results showed that the participants improved 32% in performance tests versus those who underwent sauna treatments.

Besides improving your cardiovascular functions, using saunas can help reap benefits such as detoxication, decreased depression, and lesser chronic fatigue.

Red Light Therapy vs. Saunas

What differentiates saunas from red light therapy devices is their mechanism of action. While saunas utilize heat for biological effects, red light therapy devices supply healthy light wavelengths directly to the skin and cells. Even when producing almost no heat, red light therapy devices help with cellular function improvement and support bodily balance. Simply put, red light therapy helps energize the body with light, while saunas heat your body.

How does red light therapy work?

Mitochondria, the powerhouse of our cells, is wonderfully affected by certain wavelengths of natural light. This helps in producing energy within the cells of our body, feeding photons to our cells from natural light via red light therapy.

What about clinically-proven wavelengths?

We feel warm when exposed to sunlight and other heat sources such as fire and hot coals because most of the wavelengths, including ultraviolet (UV), are rapidly absorbed by the outer layers of the skin tissue as heat.

However, unknown to many, some wavelengths have the unique capability of boosting your cellular functions and energy. These are those few wavelengths that can penetrate human tissues more effectively, having photons power-up your “cellular batteries.”

What to Look for When Buying Red Light Therapy Devices and Saunas?

One of the first few things you need to look for in saunas is the temperature it produces. You need to consider some other factors, including the type of wood, the heating unit (Is it conventional or infrared? Is it near far or full-spectrum?), finishes and stains, price, and more.

On the other hand, some of the factors you need to consider when choosing a red light therapy device are the device’s light energy output, light color or frequency range in terms of nanometers, warranty, body or treatment coverage area, the price, and the credibility of the company provider.

Light Therapy and Saunas: Friends with Benefits

Saunas and red light therapy devices offer a wide range of natural health benefits, which surprisingly go well with each other. They both support balance and health to improve your fitness and function but do not overlap with each other’s effects because of energy supplementation in distinct forms and wavelengths. What a great combination of complementary natural therapies!

Here at Kaiyan Medical, we provide different types of red light therapy devices for various medical, wellness, and aesthetic uses. To see our list of products, click here.

References:

https://www.health.harvard.edu/staying-healthy/saunas-and-your-health

https://www.healthline.com/health/fitness-exercise/are-saunas-good-for-you

Scoon GS, Hopkins WG, Mayhew S, Cotter JD. Effect of post-exercise sauna bathing on the endurance performance of competitive male runners. Journal of Science and Medicine in Sport. 2007 Aug.

Crinnion WJ. Sauna as a valuable clinical tool for cardiovascular, autoimmune, toxicant- induced and other chronic health problems. Altern Med Rev. 2011 Sep.



Red Light Therapy For Hair Loss

If you’re one of the 35 million men or 21 million women in the United States who are losing their hair, you know how hard it can be to slow down getting bald. Creams, pills, and other treatments are often touted as solutions, but even if they do work, they come with side effects. Meanwhile, hair loss takes a tremendous mental toll. Among the most common effects are diminished self-esteem and confidence, as you notice others wearing hairstyles you couldn’t possibly pull off. And while some people rock the bald look, it’s not for every guy suffering from male pattern baldness and it’s rarely an option for women.

If this sounds like you, red light therapy is worth a look. Red light therapy for hair loss is backed by research, is completely natural, and can slow–or in some cases, reverse–hair loss without disruptive side effects. If you’re curious how this is possible, what the most relevant studies say, and–more importantly–if it will work, this article is for you. From cellular growth to the proper how-to steps, read on to uncover how red light can help you get your hair back.

Why Do We Lose Hair?

According to the International Society of Hair Restoration Surgery, almost half of men show noticeable hair loss by reading middle age. Surprisingly, the numbers are even higher among women: by the age of 60, nearly 80 percent of women show noticeable hair loss.

So, why do we lose hair? Briefly, losing hair helps us making room for new growth. A typical human will have up to 100,000 hairs on their head, and it’s only normal to lose 50–100 every day. After that, that causes get more complicated.

A few of the most common causes include:

Genetics

The most common cause of hair loss is hereditary hair loss or androgenetic alopecia. Male pattern baldness is characterized by M-shaped hair loss that begins at the temples and a bald spot in the back. It can begin as early as puberty or later in life. Female pattern baldness generally manifests as thinning on the head's top and crown, widening the center part but not affecting the front hairline.

Stress

Both acute and chronic stress contribute to hair loss in men and women. In acute stress, hair loss is often tied to a specific cause such as a sudden loss of a loved one, an accident, illness, or surgery; this hair loss may be temporary. Chronic stress, including job stress, relationship stress, and financial stress, also appears to accelerate hair loss.

Poor Nutrition

Specifically, inadequate protein intake affects hair follicles and contributes to hair loss. While over 40 million Americans are malnourished due to poverty, easy accessibility of junk food means that while many Americans get enough calories in their diets, they do not necessarily get the nutrition they need.

Red Light Therapy for Hair Loss


Given the side effects, cost, limited success, and ongoing hassles of these common hair restoration treatments, it makes sense to look at an alternative that is painless, non-invasive, has no side effects, and can actually enhance your health in a variety of different ways at the same time. Red light therapy is that option. Also red light therapy can help improve various other conditions, including joint pain from arthritis, sun damage, and nerve damage, to name a few. In fact, it can even treat one of the root causes of hair loss: thyroid problems.

What Is Red Light Therapy?


Red light therapy is a phototherapy that uses specific wavelengths of light to reduce inflammation, accelerate healing, and promote a healthy skin tone. Red light is part of the visible light spectrum (not to be confused with infrared light or ultraviolet light, invisible to the human eye) and is bioactive in humans. This means that our bodies respond to it beneficially in much the same way that plants respond to sunlight: by creating more energy at the cellular level.

Red light (also called low-level light therapy or LLLT) for hair loss was discovered somewhat by accident in the 1960s when mice were given chemotherapy. The chemotherapy-induced hair loss, but when the mice were irradiated with red light, the fur grew back thicker than before. Modern red light therapy works similarly, using high-power LEDs to saturate your body with wavelengths of therapeutic light. It typically uses visible light in various colors, but the red and infrared ranges are best for a wide variety of conditions, including hair loss. While sunlight provides a complete spectrum of wavelengths (including red light), it also contains harmful UVA and UVB wavelengths. Using the red light frequency alone has no side effects, such as burning or skin damage.


How Red Light Therapy Restores Hair


Red light is especially effective at treating hair loss; specifically, light in the 620nm (nanometer) to 660nm wavelengths work best. It works by increasing blood flow in the scalp; this stimulates the metabolism in hair follicles, resulting in more hair production.

You lose hair during hair loss but not the follicles–the tube-like formations that anchor hair to the skin. At the base of each follicle is the hair bulb (the whole thing looks somewhat like a tall vase). At the bulbous part of the vase are the papilla and the matrix; this is where hair begins to grow. We see as “hair” mostly a protein called keratin that makes up the hair shaft. When the hair follicles and the papilla and matrix cells are not functioning properly, they cannot support hair growth,, causing it to slow or cease altogether.

Red light penetrates the skin to the base of the hair follicles, stimulating the cells, papilla,, and matrix to produce more energy, which results in these cells replicating more successfully. This replication leads to new hair growth from these previously-dormant follicles. Red light also:

Stimulates Adenosine Triphosphate (ATP) production, a coenzyme responsible for fueling cellular structures. Increases in ATP cause individual cells within the hair follicle to increase their activity, including the rate at which they replicate. Restoring the energy of the hair follicles' cellular structures means the papilla creates more keratin, which results in hair growth.

Increases collagen production. Hair is primarily made up of a protein called keratin. While collagen — another type of protein — isn’t present in hair, it acts as an antioxidant to fight damage caused by free radicals (compounds that develop in the body during stress, environmental pollutants, poor nutrition, etc.). Free radicals damage hair follicles, which contributes to their inability to grow hair. Increased collagen means less oxidative damage, which can lead to increased hair growth.

Increases the creation of new capillaries, which improves blood flow to the scalp and brings oxygen and nutrients to hair follicles,, and removes waste that can lead to hair follicle damage. One study linked improved blood flow to the growth of thicker, healthier hair. Barbers have long encouraged men to massage their scalps to increase blood flow, but increasing blood flow using red light is generally more effective.

Cases Where Red Light Does NOT Work

It’s important to note that while red light therapy is effective for many types of hair loss (especially alopecia or temporary hair loss due to hormonal imbalances or illness), it’s not effective 100% of the time. For example, hair loss due to chemotherapy will continue until the treatment is stopped. The same applies to hair loss due to the side effects of other medications. Also, any hair follicles that have been destroyed due to injury, surgery, burns, or other permanent injuries will not grow back. And remember, please see your doctor if you experience sudden or dramatic hair loss, which can signal a serious underlying condition. Red and Near-Infrared Light: a Potent Combination

More References

https://pubmed.ncbi.nlm.nih.gov/30843235/

https://pubmed.ncbi.nlm.nih.gov/29957664/

https://pubmed.ncbi.nlm.nih.gov/29797431/

https://pubmed.ncbi.nlm.nih.gov/28328705/

https://pubmed.ncbi.nlm.nih.gov/25124964/

Putting the Light on Psoriasis

Psoriasis is an autoimmune inflammatory skin disease where the skin cells build up and form scales and itchy, dry patches over the surface. It is a misunderstood skin condition. The misbelief is that it not treatable and affects a particular gender or at a certain age. However, it can affect both men and women equally, and more than 5 million adults deal with this skin disorder — which is about 2% of the U.S. population.

Another common misconception is that it is contagious and can spread from one person to another. Well, Psoriasis is an immune system problem in which your immune system does not work as it should normally do.

Light Therapy: The Advanced Way

With some options available for Psoriasis, light therapy is one of the oldest, safest, effective, convenient, and highly preferred treatment by dermatologists. It has been widely used to treat stable psoriatic lesions, including different parts like the trunk, scalp, arms, and legs, and partial nail psoriasis. The treatment of light therapy is available in a variety of light with different mechanisms of action. Based on the bandwidths, the varied versions includes ultraviolet B (UVB), psoralen ultraviolet A (PUVA), pulsed dye laser (PDL), photodynamic therapy (PDT), intense pulsed light (IPL), light-emitting diodes (LED), etc.

How it Works

Light therapy has a very long history of dermatological benefits. Psoriasis happens when the skin cells there is an abnormal production of skin cells. Light therapy works by slowing down the excessive production of skin cells on the epidermis layer. This reduces plaque formation. It also reduces inflammation and limits the growth of skin cells by affecting the functioning of the DNA.

Many clinical studies and researches have displayed positive and effective result in the treatment of various types of Psoriasis like –

  • Small areas of stubborn, thick plaque psoriasis
  • Palmoplantar psoriasis (on hands and feet)
  • Nail psoriasis
  • Scalp psoriasis

Why do Dermatologists Prescribe Light Therapy?

Light therapy treatment can:

  • Slow down the growth of abundant skin cells
  • Repress the functioning of an overly active immune system
  • Reduce inflammation and allow the skin to heal itself
  • Reduce or eliminate the dry and itchiness

Light Therapy Mechanism

Light therapy can be delivered on any affected skin areas such as the hands or scalp, or across their whole body. But proper care and protection are given to the skin areas, such as the eyes and genitals, before treatment.

The treatment doesn’t work in on-go. Several sessions are required as the effect is gradually seen in patients. The treatment requires multiple sessions where the amount of light is gradually increased per session. The light exposure is not instant and varies for a different duration depending on the skin condition severity.

The sessions give proper time to heal the skin. Usually, the sessions go from two to three months. We need to understand the fact that every person’s skin reacts to light therapy differently. Hence, how much improvement one sees in their psoriasis symptoms and how long those benefits last depends totally on their system.

Now the time has changed, and technology has brought more convenience in getting the treatment. Kaiyan Medical provides you numerous products that you can use at your home and enjoy your daily activities without getting disturbed. Break the old and mainstream treatments and adopt effective light therapy to let your skin and life heal completely!

References:

The Effect of Green & Red Light Therapy on Hearing

Low-level laser therapy

Low-level laser therapy (LLLT) has been practiced for over 20 years in Europe and has been introduced in the United States as a treatment for pain and postsurgical tissue repair. It has been proposed that laser energy in the red and near-infrared light spectrum may aid in the repair of tissue damage. A proposed mechanism for this therapeutic effect is the stimulation of mitochondria in the cells to produce more energy through the production of adenosine triphosphate.

Studies in humans have investigated the effects of LLLT on both hearing loss and tinnitus, with equivocal results. Some studies have found an improvement in hearing thresholds and tinnitus symptoms.

The Subjects

A total of 35 adult subjects were enrolled in the study. Two subjects withdrew from the study due to loss of interest and/or scheduling difficulty. The data from three additional subjects were not included in the analysis. One subject yielded unreliable audiometric and speech understanding data, speech scores could not be obtained from one subject with a profound hearing loss, and calibration problems compromised data from the third subject. Data from the remaining 30 subjects were included in the analyses. The experimental protocol was approved by the Institutional Review Board of The University of Iowa, and written informed consent was obtained from all participants.

The Device

An Erchonia EHL laser was used to provide the laser stimulation. The device was a portable unit that consisted of a hand-held probe and a main body. The probe contained two laser diodes. One diode produced light in the green part of the visible light spectrum (532 nm wavelength), and the other diode produced light in the red part of the visible light spectrum (635 nm wavelength). Both diodes produced energy levels of 7.5 mW (class IIIb). The laser beams from both diodes were dispersed through lenses to create parallel line-generated beams, rather than spots. A second Erchonia EHL device served as the placebo. It was identical to the treatment device, except that the laser diodes were replaced with nonfunctioning standard light-emitting diodes.

The Groups

The study used three groups: treatment, placebo, and control. Subjects were pseudorandomly assigned to one of the three groups.

Initial group assignment was random with occasional adjustment to ensure that the three groups were similar in terms of number of participants, female/male ratio, mean age of participants, and mean pure-tone audiometric thresholds. The treatment group received the laser treatment protocol using the functional laser device. The placebo group also received the laser treatment protocol, but using the nonfunctioning laser device. The control group made similarly timed visits to the laboratory but received no real or feigned “treatment.” The study used a repeated-measures design, with each subject taking a battery of pretests, followed by treatment followed by a battery of posttests.

Analysis

Data were obtained from both ears of each subject. Since no obvious differences were seen between left and right ears, data from both ears were combined in the following analyses. Strictly speaking, this likely violates the statistical assumption of independent sampling, since the test results from left and right ears of a single subject are likely to be highly correlated. None of the statistical tests used in the analyses are robust to the assumption of independent sampling, and the effect of including both ears is likely to be that of artificially increasing the sample size, making it more likely that a statistically significant result will be found. All statistical tests were conducted using a significance level of .

Conclusions

No statistically significant effect of LLLT on auditory function was found, as assessed by pure-tone audiometry, speech understanding, and TEOAEs in this test. Additionally, no individual subjects showed any clinically significant change. It remains possible that other methods of LLLT could have an effect on hearing. The type of device used was not the best one for this type of study. Further research elucidating the anatomic and physiologic bases for therapeutic effects of LLLT on hearing are needed before further clinical testing is warranted.

More References

Clinical Study | Open Access. Volume 2013 |Article ID 916370 | https://doi.org/10.1155/2013/916370

ClinicalTrials.gov (NCT01820416)

T. I. Karu, “Molecular mechanism of the therapeutic effect of low-intensity laser radiation,” Lasers in the Life Sciences, vol. 2, no. 1, pp. 53–74, 1988.View at: Google Scholar

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Why Hollywood Stars Love Light Therapy

Julia Roberts Uses LED Face Mask | PEOPLE.com
Julia Roberts using LED light therapy mask

From the red carpet to the spotlight stage, Hollywood’s stars are no strangers to the powerful power of light. Their skin is glowing thanks to the latest light-based skin treatment. Stars like Julia Roberts, Kate Hudson, and Jessica Alba have been sharing their experience with LED light therapy masks that are designed to boost collagen, reduce inflammation and banish acne-related bumps and scars.

In Kaiyan Medical we can develop your own beauty light therapy mask worth of the celebrities’ skin.

Kate Hudson using LED light mask
How it Works

These amazing light masks are recommended by dermatologists and estheticians who credit the masks’ multi-colored UV-free wavelengths with improving clients’ complexions.

“Tiny particles of light are called photons, which cells absorb and transform into ATP (adenosine triphosphate), the form of energy that cells use to carry out normal functions,”

says L.A.-based celebrity facialist Shani Darden.

“ATP is then used to power the metabolic process and repair and regenerate cells.”

In short, just like LEDs have been proven to encourage plant growth (what’s a greenhouse without a good grow light?), LEDs can have a similar stimulating effect on skin cells by jump-starting the rejuvenation process.

But not all lights are created equal. Different wavelengths of light have different benefits.

“Blue-light wavelengths destroy bacteria in the skin to improve acne,”

says Toronto-based cosmetic dermatologist Dr. Martie S. Gidon. It’s worth noting that LED therapy is not effective at treating hormonal acne and is only recommended for inflammatory acne — in other words, pimples caused by bacteria — and works best when paired with topical acne medication.

Anti-aging benefits

For anti-aging results, red light therapy is for you.

“Red-light wavelengths penetrate more deeply than blue light and stimulate fibroblasts to produce collagen, resulting in tighter skin and smooth fine lines,”

says Dr. Gidon, who also praises the red light’s anti-inflammatory effect for use post-facials and peels. Another light used in combination with the other two is infrared.

“It accelerates healing and encourages greater product absorption,”

says Shani who recommends clients use a combination of both blue/red light therapy and infrared.

Home LED masks have been growing in popularity, especially with the COVID restrictions. You can opt for flexible home masks for personal use or well, the spa line which packs more lights and cover a bigger zone. With so effective results, it’s no wonder stars like Michelle Williams and Rachel Weisz are opting to lay down inside LED beds in order to treat their entire bodies to the rejuvenating powers of the lights.

If you have question on how to create your own beauty mask, don’t hesitate in contacting us. We will guide you in the whole creative process.

More References


https://ca.hellomagazine.com/health-and-beauty/02017032134254/guiding-light

https://www.womansworld.com/posts/celebrities/julia-roberts-light-therapy-mask

Therapeutic and Aesthetic Uses of Blue & Red Light Therapy Together

Acne vulgaris remains one of the most common dermatologic disorders. Clinicians are always searching for new therapies to utilize in their therapeutic armamentarium for this common skin concern. We have many medical therapies at our disposal and these have proven useful in many cases in controlling the disease process. However, some patients need or want other therapies, and laser and light treatments for acne vulgaris have become popular over the past several years.

Regarding LED light therapy for the skin, “There is a science to support it” says Angela Lamb, director of the Westside Mount Sinai Dermatology Practice,

“but it’s important to know its limitations.”

Exposing your skin to different forms of low-level LED light does have anti-bacterial and anti-inflammatory benefits, which is why they’re commonly used for treating redness or acne. Blue light therapy in the right wavelength can be FDA-cleared.

Light Therapy with Aduro Mask

Other blue light trials have supported the efficacy of blue light. Papageorgiou described their experiences with phototherapy comparing a mixed blue and red light system (415 and 660nm) with blue light therapy alone and white light therapy. The results showed that the combination of blue and red light decreased inflammatory acne vulgaris lesions by 76 percent versus 58 percent in the blue light alone group, which were both better than white light (25%). Meffert reported experiences with a high-energy, broad-spectrum, blue light source that combined blue light and UVA with a wavelength of 410 to 420nm and noted marked improvement in patients with pustular acne vulgaris after 10 treatments.

There are a variety of at-home light treatments out there like the Aduro mask (which is patented with medical grade quality) who uses red, orange, purple, infrared, cyan, blue,green and yellow light — but typically what you’ll see on shelves are ones harnessing blue or red light . Blue light is a shorter wavelength that destroys acne-causing bacteria on the skin’s surface, while red light penetrates deeper to help with inflammation, but Hooman Khorasani, the chief of the division of Dermatologic and Cosmetic Surgery at the Icahn School of Medicine at Mount Sinai, says that both blue- and red-light therapy “may reduce the size of the sebaceous glands, so you don’t produce as much oil.”

Blue & Red Light Therapy

The good thing about light therapy is that experts say that there aren’t really downsides if you’re willing to give it a shot. Light treatments have been shown to be relatively safe, with minimal side effects. For acne, Khorasani notes that LED devices won’t take the place of acne fighters like retinoids; instead, they should be used in concert with a multipronged treatment plan — and never for severe acne. If you are combining them with retinoids, Lamb also suggests alternating the days you use either of them, to avoid photosensitivity.

When you combine the blue and red light using the aduro mask, you can get a pink/purple amazing color that will help remove the p-acne causing bacteria from the skin while purifying and cleansing it. Also, you will speed up the healing process and rejuvenate the skin cells increasing the cell regeneration.

More references

https://www.accessdata.fda.gov/cdrh_docs/pdf9/K093963.pdf

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013592

Sigurdsson V, Knulst AC, van Weelden H. Phototherapy of acne vulgaris with visible light. Dermatology. 1997;194:256–260. [PubMed] [Google Scholar]

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Light Therapy & Vitiligo

Our life is full of patches!

Patches in job, career, personal life, and skin too! When we can handle the life patches and hardship with determination, then why not with skin. The skin patches disease is termed as Vitiligo. It is a medical condition where skin loses its color. Vitiligo affect not only physically but also cause a mentally & emotionally. According to VRF, this condition affects 2% of the world’s population. So, around 70 million people across the world have vitiligo. It can affect can affect people of any age, gender, or ethnicity.

How does it occur?

Well many of us are not aware of the biological reasoning behind the condition. It occurs when cells responsible for making skin pigment called melanocytes get destroyed. It can affect any part of your body like limbs, back, neck, face, etc. The body stops producing melanin — the pigment that gives your skin, hair and eyes color.

The symptoms of Vitiligo are like – Patchy, loss of skin color, which usually first appears on the hands, face, and areas around body openings. Other like premature whitening or greying of the hair on the scalp, eyelashes, eyebrows or beard. Vitiligo is an auto-immune disease, where the person’s immune system mistakenly attacks its own body (or host body). Other than that, the skin cells (melanocytes) of the affected person appears to unable to deal with the imbalance of antioxidants and harmful free radicals generated inside the body. This results in cell damage and death.

Light therapy - the hope

Today a number of treatments which are aimed for the restoring the discoloration of the skin. But the best and the convenient is Light Therapy. Especially the narrow-band ultraviolet B (NB-UVB) has come up as one of the safest and most effective therapy for this skin condition.

In this treatment, the depigmented or discolored skin is exposed under a specific wavelength of light for a specific amount of time and using a specified amount of light monitored or prescribed by the dermatologist. The duration of a session can gradually increase as one’s progress based on his/her skin’s response to the light.

Light therapy treatment often involves the usage if specific light which are used in combination with topical medications that are applied to the skin. The topical treatments can be topical steroids, topical calcineurin inhibitors or topical Vitamin D etc. Although the treatment can be used without the topical as well. Topical medications may also be used on their own, without light therapy, however, when the two treatments are used together, the results are typically seen well.

According to the studies, the light therapy session have a great response to treatment. The greatest response is shown majorly on the face and neck. Several retrospective and prospective studies have displayed superior repigmentation, color matching results.

Light therapy is a hope for people who perceive it as an incurable disease. The technology of light therapy helps people to overcome the physical as well as mental aspect of their body.

References:

https://nyulangone.org/conditions/vitiligo/treatments/phototherapy-laser-treatment-for-vitiligo

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536079/

https://www.medscape.com/answers/1068962-87933/how-is-narrowband-uv-b-nb-uvb-used-to-treat-vitiligo

https://www.umassmed.edu/vitiligo/vitiligo-treatment/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607222/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817459/

Healing Muscular Pain with Light Therapy

Light Therapy Healing Muscular Pain

When it comes to pain, we could hardly avert it! Especially the muscle pain. Given that the human body has over 600 muscles, it is tough to avoid muscle pain. Evidently, one out of three Americans is affected by muscle pain annually.

Not only this, Musculoskeletal pain affects around 116 million Americans, which results in poor productivity, missed work or school, fatigue, and lost interest in work.

But doesn’t we treatments for this chronic pain? Of course, we do have several options. Currently, therapies available consist of non-steroidal anti-inflammatory drugs, steroid injections, pain medications, and surgery. Each of these has its own specific risk profiles.

What we need now is an effective solution that is less time-consuming, low risk, safe and non-invasive, and yet cost-effective. All these features are available in treatment; we call Low Laser Light Therapy (LLLT). Light therapy has been in the medical field over the past forty years. Light therapy has been demonstrated to lessen inflammation and edema, promote healing in a range of musculoskeletal pathologies. LLLT is being accepted around the globe. This is an advanced, cost-effective, non-invasive therapy for pain that could elevate the quality of life while reducing your financial strains. The causes of muscular pain are numerous. Hence, LLLT helps people from all fields like sports, fitness, medical, and even old age.


Mechanism of LLLT

In this process, light with a wavelength in the red to the near-infrared region of the spectrum (660nm–905nm) is employed on the skin surface. The reason for using these wavelengths is that they have the ability to penetrate the skin and soft/hard tissues. From various conducted clinical trials, this treatment is proven to have a good effect on pain, inflammation, and repairing of the tissues. The therapy goes from 30 to 120 seconds or more a week, depending upon the pain's severity.

Based on the tissue condition, the therapy can go on for weeks or months. LLLT has resulted in relief and reduction of inflammation, pain relief, and accelerated tissue regeneration.

But how does the light actually work?

LLLT in the Treatment of Pain

Do you know that many acute orthopedic conditions such as strains, sprains, muscular back pain, frozen shoulder, neck and back pain, etc., are amenable to Low Laser Light Therapy (LLLT)?

The Infra-Red light relieves pain in a different section of the body and increases relaxation sensation while also comforting the muscles. LLLT has been shown to enhance the multiplication of cells like fibroblasts, keratinocytes, endothelial cells, and lymphocytes. Fibroblasts and keratinocytes are two major cell types that respond to the inflammatory phase in the repair/regeneration process.

LLLT can enhance neovascularization, promote angiogenesis, and increase collagen synthesis to succor in the healing of acute and chronic wounds. The LED light sessions have shown the ability to heal skin, nerves, tendons, cartilage, and bones. Low-intensity LLLT stimulates mitochondria and also enhances the mitochondrial membrane potential.

The peripheral nerve endings of nociceptors (also known as the pain receptors), consisting of the thinly myelinated and unmyelinated, slow-conducting C fibers, lie within the epidermis. This complex network converts harmful stimuli into action potentials. Moreover, these nerve endings lie on the surface or superficial in nature, making the LLLT wavelength penetration work easy.


Hence, with the rise of chronic pain in different countries, it is imperative to validate cost-effective and safe techniques for managing painful conditions, allowing people to live active and productive lives. Light therapy is constantly evolving in relieving muscular pain. It improves the muscle's endurance, reduces muscle soreness, joint pain, and inflammation.

It’s time to let go of the pain!!

Experience the difference with light therapy from Kaiyan Medical.

More References:

https://pubmed.ncbi.nlm.nih.gov/12605431/

https://pubmed.ncbi.nlm.nih.gov/27472858/

https://arthritis-research.biomedcentral.com/track/pdf/10.1186/s13075-015-0882-0

https://www.sciencedirect.com/science/article/pii/S0004951414601276?via%3Dihub

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743666/

The Key for Better Sex - Red Light Therapy

The famous fitness coach Ben Greenfield uses red light naked every morning. He flips a switch, flooding the room with a bright red glow. Then he stands naked in the red light for 20 minutes.

“It seems to like, wake you up a little bit; it kind of simulates sunrise,” Greenfield tells. “And it’s almost mildly addictive — the feel-good effect of how you feel after you use one of these.”

Greenfield, a 39-year-old fitness instructor, is an evangelist for red light therapy, a treatment that’s increasingly popular in the world of sports, beauty, and biohacking. Some converts to red-light therapy treatment soak in the ruddy glow for a very personal reason.

Red Light for Testosterone
Red Light Therapy

Light therapy has been for hundreds of years. Recently, we can trace it back to 1967 with Hungarian scientists, red light therapy, scientifically known as photobiomodulation or low-level laser (light) therapy, has made a comeback in the last two decades.

Michael Hamblin, a researcher at Massachusetts General Hospital and professor at Harvard Medical School, explains in a 2017 research paper on the topic that the treatment was confined to a “SCIENTIFIC WASTELAND,” and widely considered “SNAKE OIL.”

But recent studies suggest red-light therapy can improve skin quality, addictions, pets’ mood, sleep quality, depression, muscle recovery, and relieve pain.

Indeed, some studies suggest light therapy stimulates mitochondria, a.k.a. the “powerhouse” of a cell, and increases the production of adenosine triphosphate, the organic chemical that carries energy in the body and plays a big role in metabolism.

Bio-hacking yourself

In Kaiyan Medical, we are on a constant quest to optimize our brains and bodies. Some studies have actually demonstrated that exposing the torso or the testes to light can potentially increase testosterone. In fact, studies on the effects of light on the testes go way back to 1939, when researchers exposed various parts of men’s bodies to UV light. They found that men’s testosterone levels went up by 120% when the participants’ chests were exposed to UV light, and they went up by 200% with UV exposure to the genital area.

Sunlight exposure directly to the testes reportedly has an even more profound effect, boosting production in Leydig cells (the cells that produce testosterone) by an average of 200%

The theory is this: while sunlight has many beneficial effects, such as vitamin D production and improved mood, it is not without its downsides. Too much exposure to sunlight, particularly to sensitive areas like the skin around your precious ball sac, can create sunburn, excess radiation, inflammation and damage. And let’s face it: you don’t want a shrunken, shriveled, dehydrated dick, no matter how impressive the tan.

Red light, however, is different than sunlight. Red light is comprised of light wavelengths in the range of 600–950 nanometers (nm). According to red light therapy proponents, red light works to stimulate ATP production, increase energy available to the cell and in particular, increase the activity of the Leydig cells in your testes, which are the cells responsible for testosterone production.

Optimizing Sex

In the last five years, light therapy researchers and red-light therapy companies set their sights on men like Greenfield — the guy who gets naked every morning in his home office.  “The impact of [low-light therapy] on sexual health is an emerging field, but I see its potential to improve sexual function and libido with recent studies,” Hamblin says. “It has been shown to improve sperm function and may have applications in increasing fertility in both men and women.”  Research on sexual health applications of red-light therapy is relatively minimal in men, and basically nonexistent for women. A few studies in animals suggest red light therapy might influence LEYDIG CELLS — the body’s sperm producers, which live in the testicles. Another study in humans suggests red light therapy can increase testosterone levels and sexual satisfaction.

Don't let the fear defeat you

Sexual health issues — from “low T” to erectile dysfunction — can be challenging to treat because of the social stigma, Goldstein explains. There’s a “fear,” the urologist says. Many men are ashamed and avoid seeing a doctor.  “If they can get something over the counter that's purported to help them, millions of men will be willing to try it and maybe they would never buy it again,” Goldstein tells.  “Good advertising and good marketing will create a market for a product, whether it's proven to be of value or not.”  

Reduce Infertility

One of the biggest concerns for those who suffer from Low-T is infertility. Several studies show that red light therapy helps increase sperm motility, which is essential for successful impregnation. In 2017, researchers from the University of California, San Diego, found that sperm exposed to 630nm red light increased sperm swimming speed and force.

A similar study by researchers from Iran found an after exposing sperm to an 830nm NIR light device. Sperm motility is associated with cellular energy; more energized sperm will swim with greater vigor. This is a vital component of male reproductive health, and success in improving sperm motility points to the use of red light therapy as a way to treat male infertility.

Red Light for Testosterone
Feeling like a super hero

On top of using red light, both Greenfield and Wiles eat healthy, work out regularly, and practice stress-management techniques. Which habit, or a combination of each, helps them “optimize” their sex life or their physical health isn’t clear.

Even though the research doesn’t match their claims — yet— Greenfield and Wiles have no intention of slowing down.  “Before I go and give a presentation or if I'm giving a lecture or even if I'm just seeing a patient in clinic, I'll go ahead and throw that thing on and I will feel like a million bucks," Wiles says. "I’ve noticed increased overall sexual health, sexual satisfaction, and stamina."  Recently, Greenfield has been shining the light for one very specific reason: He and his wife are trying for a baby.  “Sometimes if I know I've got like a date night with my wife or we're going to have sex that night, I'll wait until the evening to do the treatment because the immediate effects are even better, especially the blood flow," Greenfield says.  "Erectile quality is just better right after you use it.”

More References

https://platinumtherapylights.com/blogs/news/red-light-therapy-for-boosting-testosterone

https://www.inverse.com/mind-body/red-light-therapy#:~:text=A%20few%20studies%20in%20animals,testosterone%20levels%20and%20sexual%20satisfaction.

Light Therapy - Color Meaning

Introduction to Color Light Therapy

Color Light therapy is based on the idea of restoring balance by applying color to the body. Its history is rooted as far back as the Mayan culture.

In India, Ayurveda, an ancient form of medicine practiced for thousands of years, is based on the idea that every individual contains five elements of the universe that are present in specific proportions unique to each individual, including their personality type and constitution. When these elements are out of balance, Ayurveda works with the energies inherent in the colors of the spectrum to restore this balance.

In ancient Egypt the art of healing with color was founded in the Hermetic tradition, the Ancient Egyptians and Greeks used colored minerals, stones, crystals, salves, and dyes as remedies, and painted treatment sanctuaries in various shades of color.

In China, traditional Chinese medicine incorporates color to be associated with each organ and elemental system. This healing method looks at the idea that every individual is a balance. The first color wheel was invented by Sir Isaac Newton. He split white sunlight into red, orange, yellow, green, cyan, and blue. He then joined the two ends of the color spectrum together to show the natural progression of colors.

Light Therapy has been valued throughout history as a remarkable source of healing. Today, the therapeutic applications of light and color are being investigated in major hospitals and research centers worldwide. Results indicate that full-spectrum, ultraviolet, colored, and laser light can have therapeutic value for a range of conditions from chronic pain and depression to immune disorders.

Wellness Benefits

Light Therapy has been reported, as part of a healthy lifestyle, to temporarily reduce swelling, relieve pain, decrease inflammation, accelerate open wound healing and greatly reduce overall recovery after medical/surgical procedures. Patients have demonstrated an increased range of motion, decreased muscle tension and spasm, and improved circulation.

Rejuvenating LED light therapy can be used for temporary pain management such as joint and back pain, sore or torn muscles, sprains, arthritis, post-surgical scars, burns, wounds, and more. When used with infrared technology, light therapy (phototherapy) is one of the most effective and non-invasive ways to improve overall wellness.

Light therapy is also used to temporarily relieve Seasonal Affective Disorder (SAD). SAD affects individuals when the lack of sunlight results in seasonal depression. Phototherapy helps with SAD by resetting the internal biological clock (Circadian rhythms), helping individuals sleep better, and regulate their mood. Even companies, such as GE and Philips, have created phototherapeutic products to improve and regulate mood.

Cosmetic Benefits

Light therapy is also a growing treatment for anti-aging. Many individuals have seen a temporary reduction in the appearance of fine lines, wrinkles, crow’s feet, and age spots.

Light therapy is “effective at improving the appearance of the face, neck, and chest by reducing the signs of aging, wrinkles and age spots”, says Web M.D. Combined with infrared therapy, LED phototherapy can be a great way to revitalize skin.

Healing With Color

Color is light split into different wavelengths vibrating at different speeds and at different frequencies. Objects that ABSORB all wavelengths and DO NOT reflect are black in nature. Objects that REFLECT all wavelengths and DO reflect are white in nature. Between black and white lies COLOR. Colors are wavelengths of energy that, to us, appear as color because of the potential and capabilities of the object to either absorb or reflect the energy.

Red Light

In the early 1990s, RLT was used by scientists to help grow plants in space. The scientists found that the intense light from red light-emitting diodes (LEDs) helped promote the growth and photosynthesis of plant cells.

The red light was then studied for its potential application in medicine, more specifically to find out if RLT could increase energy inside human cells. The researchers hoped that RLT could be an effective way to treat the muscle atrophy, slow wound healing, and bone density issues caused by weightlessness during space travel.

You may have heard of red light therapy (RLT) by its other names, which include:

  • photobiomodulation (PBM)
  • low-level light therapy (LLLT)
  • soft laser therapy
  • cold laser therapy
  • biostimulation
  • photonic stimulation
  • low-power laser therapy (LPLT)

Red is called “The Great Healer”. So far is the most popular light therapy. To wind down before bed, use red light. “The color signals that it’s night, which may encourage the body to produce melatonin,” says Michael Breus, Ph.D., an advisory board member for SleepScore Labs.

Red light can also improve your workout. Just one to five minutes of exposure to red and infrared light right before exercise boosted strength and prevented soreness, says Ernesto Leal-Junior, Ph.D., the head of the Laboratory of Phototherapy in Sports and Exercise at Nove de Julho University in Brazil. “Certain wavelengths of red and infrared light-660 to 905 nanometers-reach skeletal muscle tissue, stimulating the mitochondria to produce more ATP, a substance that cells use as fuel,” he says.

Green Light

Green is the universal healing color. Originally, the color of love. Green is midway in the color spectrum; therefore, it contains both a physical nature and a spiritual nature, in equal balance and in equal harmony.

Gazing at green light can reduce chronic pain (caused by fibromyalgia or migraines, for example) by up to 60 percent, according to a study in the journal Pain, and animal studies have shown that the beneficial effects can last up to nine days. “Looking at green light seems to lead to an increase in the body’s production of enkephalins, pain-killing opioid-like chemicals. And it reduces inflammation, which plays a role in many chronic pain conditions,” says researcher Mohab Ibrahim, M.D., Ph.D.

More studies are needed before doctors can make recommendations on how and how often to use green light to treat migraines and other pain, and Dr. Ibrahim says you should see a physician before trying to treat yourself at home. But at this point research indicates that exposing yourself to an hour or two every night-either by using a green light bulb in a lamp or by wearing glasses fitted with tinted optical filters-may decrease migraines and other types of chronic pain

Helps to treat and prevent hyper-pigmentation by inhibiting the production of excess melanin which then prevents it from traveling to the surface. It will help break up the melanin clusters that are already on the surface.

Yellow Light

Yellow helps awaken mental inspiration arousing a higher mentality. Thus, it is an excellent color for nervous or nerve-related conditions or ailments; fueling the solar plexus. Yellow has a very enriching effect upon the intellect. Yellow can be used for conditions of the stomach, liver, and intestines. It can help the pores of the skin by repairing scarred tissue. These rays have an alkalizing effect which strengthens the nerves. Awakening, inspiring, and vitally stimulating the higher mind promoting self-control. Typical diseases treated by yellow are constipation, gas, liver troubles, diabetes, eczema, and nervous exhaustion. Providing clarity of thought, increasing awareness, stimulating interest, and curiosity yellow energy is related to the ability to perceive or understand.

The yellow is used for treating redness, flushing, irritation, and Rosacea. It may also reduce the appearance of the tiny blood vessels on the nose and face.

Blue Light

Blue light therapy technology is an additional option for the treatment of acne. Research has shown in-office and at-home systems produce positive results.

“Blue light therapy effectively helps alleviate this common skin condition affecting 50 million Americans and 94 percent of all females, according to Judith Hellman, MD, a board-certified dermatologist, in practice in New York City. Dr. Hellman, who practices medical dermatology and specializes in dermatological surgery, laser surgery, and anti-aging skin treatments, explains how the blue light treatment system works for acne, its uses, and her clinical experience with the technology.

Cyan Light

It is used as a gentle acne treatment to control oil production in the skin as well as reduce inflammation. It also promotes the synthesis of protein and collagen.

Orange Light

Orange has a freeing action upon the mind, relieving repression. Because orange is a blend of red and yellow, it combines physical energy with mental wisdom, inducing a transformation between lower physical reaction and higher mental response. Thus, it is often referred to as “The Wisdom Ray.” Orange is warm, cheering, and non-constricting.

Through orange, we are able to heal the physical body (red) and, at the same time, induce within the mind (yellow) greater understanding. Orange helps assimilate new ideas. Orange is the best emotional stimulant, helping to remove inhibitions paving independent social behavior. Bring joy to your workday and strengthen your appetite for life. Orange aids in repairing inflammation of the kidneys, gallstones, menstrual cramps, epilepsy, wet cough, and all sinus conditions.

Purple Light

Violet is the last color we can see before light passes on to ultra-violet. Violet purifies our thoughts and feelings giving us inspiration in all undertakings. The violet energy connects us to our spiritual self bringing guidance, wisdom, and inner strength and enhances artistic talent and creativity. Leonardo da Vinci proclaimed that you can increase the power of meditation ten-fold by meditating under the gentle rays of Violet, as found in church windows.

Light therapy uses colors for their proposed wellness abilities in treating emotional and physical disturbances. Light therapy is based on the premise that different colors evoke different responses in people. For example, some colors are considered to be stimulating, whereas others may be soothing. Color therapy has been suggested for many uses, based on tradition or on scientific theories. Consult with a health care provider before using color therapy for any use.

Infrared Light

Infrared light penetrates to the inner layers of the skin at about 2 to 7 centimeters deep. Hence, it reaches the muscles, nerves, and even the bones. Many studies have shown that a frequency of infrared light, with wavelengths from 700 to 1,000 nanometers, is best used for healing inflammatory conditions.

The use of electricity for healing purposes began in 2,750 BC when people used electric eels to give electric shocks. Electricity and magnetism were used in people with just little success. However, in 1975, transcutaneous electrical stimulation (TENS) was developed to treat chronic pain. It was not until recently that infrared therapy was developed to improve wound healing, reduce the pain caused by arthritis, boost endorphin levels, and bioactivate neuromodulators.

Infrared therapy technology allows people to harness the benefits of the sun, without being exposed to harmful ultraviolet rays. Also, infrared therapy is safe and effective, without adverse side effects. As a matter of fact, infrared light is safe and is used even for infants in neonatal intensive care.

Infrared light is absorbed by the photoreceptors in cells. Once absorbed, the light energy kickstarts a series of metabolic events, triggering several natural processes of the body on a cellular level.

Kaiyan Medical

In Kaiyan, we are in love with light therapy. We believe in the natural balance in our bodies. We develop devices such as the Aduro mask which will provide you with the full range of color light therapies.

References

https://www.estyspot.com/blogs/esthetician-tips/an-estheticians-view-of-led-therapy-benefits-for-all-7-colors

https://www.the-dermatologist.com/content/acne-treatment-blue-light-therapy-benefits-0#:~:text=A%3A%20Blue%20light%20kills%20the,oil%20glands%20in%20the%20skin.

https://www.healthline.com/health/red-light-therapy#summary

https://www.estyspot.com/blogs/esthetician-tips/an-estheticians-view-of-led-therapy-benefits-for-all-7-colors

Deppe A. Ocular light therapy: a case study. Aust J Holist Nurs 2000;7(1):41.

Geldschlager S. Osteopathic versus orthopedic treatments for chronic epicondylopathia humeri radialis: a randomized controlled trial. Forsch Komplementarmed Klass Naturheilkd 2004;Apr, 11(2):93-97.

Maher CG. Effective physical treatment of chronic low back pain. Orthop Clin North Am 2004;Jan, 35(1):57-64.

Natural Standard Research Collaboration, Chief Editors: Ulbricht C, Basch E, Natural Standard Herb and Supplement Reference: Evidence-Based Clinical Reviews, USA. Elsevier/Mosby, 2005.

Ohara M, Kawashima Y, Kitajima s, et al. Inhibition Of lung metastasis of B16 melanoma cells exposed to blue light in mice. Int J Molecular Medicine 2002;10(6):701-705.

Wileman SM, Eagles JM, Andrew JE, et al. Light therapy for seasonal affective disorder in primary care: randomised controlled trial. Br J Psych 2001;178:311-316.

Wohlfarth H, Schultz A. The effect of colour psychodynamic environment modification on sound levels in elementary schools. Int J Biosocial Res 2002;(5):12-19.

Zifkin BG, Inoue Y. Visual reflex seizures induced by complex stimuli. Epilepsia 2004;45(Suppl 1):27-29.

Fighting Breast Cancer with Light Therapy

Researcher fighting breast cancer with light therapy
"Metastatic breast cancer can be a devastating diagnosis with high rates of relapse and death, and there are currently no effective therapies,"

Nalinikanth Kotagiri, MD, Ph.D. says.

"Despite newer treatments, many patients still succumb to the disease. Major limitations include acquired resistance to therapies and serious side effects from treatment. Due to the widespread location of breast cancer cells, particularly in the bone marrow, which harbors the tumor cells as well as vital stem cells, the risk of toxicity is even higher with conventional therapies. Therefore, new therapeutic strategies that selectively destroy tumor cells, increase treatment efficacy, prevent relapse and reduce side effects by sparing the healthy stem cells are necessary."


This is why Nalinikanth Kotagiri, MD, Ph.D., assistant professor in the James L. Winkle College of Pharmacy and a cluster hire for the Cincinnati Cancer Center, is hoping to study ways ultraviolet light can activate light-sensitive drugs to treat this invasive breast cancer and provide that light at the end of the tunnel patients yearn for.

Kotagiri has been awarded the Department of Defense Breast Cancer Breakthrough Award—over $600,000 for three years—to try to do just that. His project will focus on light-mediated therapies, which could activate light-sensitive drugs to target only the cancerous cells.

"Therapies such as photodynamic therapy (PDT), involving light and a photosensitizing chemical substance, which used in conjunction with molecular oxygen can cause cell death, offer a high degree of control that is effectively used to manage cancer in early to advanced stages," he says. "It operates on a simple principle where a light-sensitive drug, which is otherwise nontoxic, introduced into certain tissues can cause cell death when activated by light. Despite the promise of PDT, it can't penetrate tissue deeply so its use is limited. Also, current light-sensitive drugs require oxygen to be effective, but many tumors, including breast tumors, have pockets of low oxygen or grow in regions where oxygen is either low or absent, which could prevent effective application of PDT in cancer treatment."

However, Kotagiri says recent work in the lab has led his team to a "two-pronged approach" in addressing these issues.

"We've been using ultraviolet (UV) light from radionuclides (radioactive nuclide or atom), which are already used to image tumors and tissues, and tried to solve oxygen dependence by using metal-based light-sensitive drugs for depth- and oxygen-independent PDT," he says. "By replacing the external light source, such as lasers and lamps, with light from radionuclides as an 'internal' light source, we've been able to better control therapy in the body.
"This could mean more effective therapies with minimal toxicity to vital organs and tissues. Since radionuclides are used in imaging and locating tumors, we can now simultaneously image and treat breast cancer metastasis using the same radionuclide."

Using animal models, researchers in Kotagiri's lab will test whether radionuclide light activation of tumor targeting, light-sensitive drugs will destroy metastatic cancer cells—including those that are resistant to traditional therapies.

"Since how we're killing the cells is not dependent on a certain molecular pathway, the technology could be applicable to treat a wide variety of breast cancers," he adds. "This has the potential to be a common image-guided treatment strategy to treat patients in early as well as advanced stages of the disease, and because of the safety of this treatment strategy, it could be effectively used alongside other treatments, like chemotherapy and immunotherapy, without the risk of additional side effects.
"This could tremendously benefit patients, as it could potentially improve therapeutic outcomes in addition to setting a precedent to tailor other FDA-approved light-sensitive drugs as radionuclide activated therapies, expanding the scope and range of the diseases these drugs currently treat. If proven beneficial, this treatment could be ready for a patient population in 5 to 10 years, since all the materials involved have already been used in humans—this could be an exciting breakthrough."
Clinical Trial - The Effects of Light Therapy to Treat Cancer-related Side Effects

ClinicalTrials.gov Identifier: NCT04418856

Besides what Kotagiri said, severe fatigue, depression, sleep problems and cognitive impairment are the most commonly reported side effects of cancer treatment. These aversive side effects are hypothesized to be related to the disruption of circadian rhythms associated with cancer and its treatment. Exposure to Bright White Light (BWL) has been found to synchronize the circadian activity rhythms but research with cancer patients has been scarce. Therefore, the proposed randomized control trial (RCT) will test if systematic light exposure (sLE) will minimize overall levels of cancer-related fatigue (CRF), depression, sleep problems and cognitive impairment among breast cancer patients undergoing breast cancer treatment (i.e., surgery, chemotherapy). SLE incorporates the delivery of harmless UV-protected BWL or Dim White Light (DWL - standard comparison in light studies) delivered to patients by using special glasses for 30 minutes each morning, during their treatment.

Learn more about the how to improve your circadian rhythm and light therapy & breast feeding

References

https://medicalxpress.com/news/2018-10-breast-cancer-therapy.html

https://www.mayoclinic.org/tests-procedures/photodynamic-therapy/about/pac-20385027#:~:text=Photodynamic%20therapy%20(PDT)%20is%20a,energy%2C%20usually%20from%20a%20laser.

https://clinicaltrials.gov/ct2/show/NCT04418856

Top Light Therapy Masks

Due COVID, everyone is obsessed with skin care these days, regular at-home routines have really leveled up, and no skin-care gadget is as intriguing as the LED light-therapy mask.

Celebrities are no longer the only ones who get to wear luminescent masks and haunt the public’s dreams by instagramming their LED selfies. There are now several regular-person versions available online, meaning anyone can harness the power of LED light, the green light for pain relief and slimming, the blue for bacteria-killing and red for collagen- and elastin-stimulating.

In Kaiyan Medical, we can create your FDA cleared light therapy mask based on your needs and market.

Here the top light therapy masks

MZ Skin Light-Therapy Golden Facial Treatment Device


Average price: $625

Buy here

If your skin is temperamental, it’s nice to have a well-rounded, high-performance mask on call. Designed to replicate MZ skin founder Dr. Maryam Zamani’s in-office treatments, it comes with five different light settings (red, blue, green, yellow, and white) so you can focus on anything from inflamed breakouts to the annoying scars and discoloration those pimples sometimes leave in their wake.


DMH Aesthetics Light Shield


Average price: $189

Buy here

Using this mask you can actually see out of it without lines obstructing your view. It’s designed to be very wearable and on-the-go, so you can continue doing whatever you’re doing while treating your skin. The Light Shield allows the wearer to enjoy RED, BLUE, and AMBER LED therapies. Specifically target post-treatment/facial redness with RED light, shown to boost circulation and speed healing

Project E Beauty Wireless LED Light Skin Rejuvenation Therapy Mask


Average price: $200

Buy here

This mask comes with seven different light colors to treat every skin-care issue imaginable on the face. Project E’s mask goes a step further with a bonus attachment for the neck, arguably the most overlooked part of skin-care routines. 99 + 40 LED lights cover your face & neck, upgraded to emit the most optimal wavelengths with 5 levels of intensity.


LG Derma Pra.L Mask


Average price: $480

Buy here

If you’re a K-beauty fan, there’s a Korean LED face mask just for you! This one comes from LG. All that appliance expertise has been channeled into a mask that hits the skin with red and infrared LED light in quick, nine-minute sessions focused on improving skin elasticity and brightness.


Dr. Dennis Gross Skin-Care SpectraLite Faceware Pro


Average price: $435

This LED mask from Dr. Dennis Gross is one of the more fashionable ones on the market. It comes with gold accents, 162 LED lights, and three treatment options to choose from: red-light therapy, blue-light therapy, or red and blue–light therapy.


TOP #1 — ADURO ® 7+1 LED FACE MASK


$399.00

Do you value personal comfort while lurking and skulking? This soft, silicone mask is less hockey goalie and more like an actual face mask that molds to your face shape for a more comfortable treatment. The aduro mask is the most advanced home-use facial mask based on light therapy.

  • 7 LED colors
  • Infra-Red Skin Boosting
  • 11 different treatments
  • 20 minutes
  • Non invasive
  • Clinically proven
  • Slows down the aging process
  • Prevents wrinkles
  • Soothes redness of the skin
  • Clears up skin imperfections
  • Stimulates cell rejuvenation
  • Improves skin tone

More information about Aduro here


Personal LED MASK - Aduro Australia
Personal LED MASK - Aduro Australia
Personal LED MASK - Aduro Australia
Personal LED MASK - Aduro Australia
Personal LED MASK - Aduro Australia

Personal LED MASK - Aduro Australia
Personal LED MASK - Aduro Australia
Personal LED MASK - Aduro Australia


Can LED Light Give me The Perfect Skin?

Following the article from the New York Times.

One day, shining light on your face may be the most important part of your skin care routine. We take a look at the newest devices.

The MMSphere, a ring of LED lights, casts a red glow over my face. It sits adjacent to my laptop so that as I write, research and procrastinate, I can simultaneously calm a fiery constellation of acne on my left cheek.

Red light’s anti-inflammatory and collagen-building effects on the skin are well documented. But this hands-free device, designed by Ellen Marmur, a dermatologist in New York, has settings for blue, green, amber and purple light too.

“It has just enough variety that people stay excited to use it,” Dr. Marmur said.

I, too, begin cocktailing. I bathe my face in blue light to kill acne bacteria while watching reruns, and immediately follow up with a FaceTime call to my mother, my face lit up in a bright green light to fight hyperpigmentation.

Skin care efficacy lives and dies by patient compliance. Most at-home LED skin care devices are small and hand-held, requiring time set aside to treat the entire face. People eventually stop using them.

Even with persistent acne as a motivator, I’ve always had trouble following LED protocols. The MMSphere ($495) is a big deal for me because it harnesses a powerful fix-everything-while-doing-nothing ease that makes it almost addictive. You actually want to use it.

“It makes people feel good, like they’re taking care of themselves,” Dr. Marmur said. “You can treat your skin while doing other things, so it’s easier to form the habit of doing it every day.”

Because, really, if we’re just sitting around — talking, eating, working — shouldn’t we be fixing our skin, too?

So How Does LED Work?

First, LED therapy is not the same as a laser treatment, which creates controlled damage to the skin to promote healing. The easiest way to understand the light-as-skin-care concept is to think of skin-friendly visible light as ultraviolet light’s benevolent counterpart.

In a process called photobiomodulation, light alters biological material; for example, UV rays from the sun change our skin in ways that can catalyze cancer and aging.

But some wavelengths of visible light alter our skin for the better, and light-emitting diodes (LED) are a source that delivers that energy.

Jared Jagdeo is an associate professor of dermatology and director of the Center for Phototherapy, SUNY Downstate Health Science University, where he studies LED therapy.

“You can alter the skin through photo-damaging with lasers, or photobiomodulation, which is a much more gentle way of changing the way the skin functions,” Dr. Jagdeo said. Red and blue light are the heavy hitters. He explained why red light in particular works so well.

“There’s a specific receptor in the mitochondria of the skin cells that red light specifically acts upon,” he said. “And that’s why red light is an ideal wavelength for changing the way the skin functions.”

Red light penetrates the skin deeper than other visible light and stimulates the mitochondria, which has an anti-inflammatory and rejuvenating effect. Collagen is built in the dermis, the skin is calmed, and wrinkles eventually fade.

Blue light doesn’t penetrate the skin as deeply but zaps acne-causing bacteria on the surface. The science on green light isn’t as solid, but in theory, it targets melanocytes, discouraging excess melanin production.

Rigorous independent studies have yet to be conducted, but Dr. Marmur did a very small clinical trial on green light for the MMSphere in which subjects self-reported a 32 percent decrease in “brown spots” after a week of green light treatment.

Is All of This Light Ok for my Eyes?

Eye safety is a valid concern, particularly because earlier this year Neutrogena recalled its LED mask over fears that it could cause eye injuries.

Brian S. Biesman, an assistant clinical professor of ophthalmology, dermatology and ENT at Vanderbilt University Medical Center in Nashville, said that most home devices aren’t powerful enough damage the eyes. The MMSphere comes with opaque goggles, but, Dr. Biesman said, the device is low energy, so it should be safe to use without them.

“Just normal blinking and eye movements should be sufficient to protect the eyes,” he said. “But never stare at a bright light source.”

More Thoughts

“As far as the F.D.A. is concerned, if I use CO2 laser resurfacing, it better work because of the amount of risk involved,” said Suzanne Kilmer, a clinical professor of dermatology at the UC Davis School of Medicine in Sacramento and director of the Laser and Skin Surgery Medical Group.

“Compare that to a home device,” Dr. Kilmer said. If it doesn’t kill you, blind you or make things much worse, it’s probably going to get approved. So it’s actually more incumbent upon the people selling home devices to show efficacy. You have to trust the people who are selling them.”

“LED is real, but it’s probably not optimized yet,” Dr. Kilmer said.

Many factors determine the amount of light your skin needs and receives: the strength of the light, the distance from source to skin, how long the light is used, and your skin color.

“Some of these lights on the market are very weak, and they may not have enough energy output to actually have a biological effect,” Dr. Jagdeo said. “Imagine a glow stick. It produces a color. But you could shine it on your face all day, and it’s not going to change the way your skin works.”

Furthermore, the medical community has yet to establish standard doses for treating conditions like hyperpigmentation and acne at home. Dr. Marmur based her MMSphere dosing on Blu-U, an in-office blue light that is commonly used as an alternative therapy for precancerous lesions.

“Consistent Sphere treatment for seven weeks will equal the energy given in the office with the Blu-U,” she said.

Another device, the Dr. Dennis Gross DRx SpectraLite FaceWare Pro, $435, emits red and blue light in a mask format, and each session is only three minutes. The mask’s LEDs are in contact with the skin, which may be a more effective treatment. Dr. Jagdeo said that you lose some energy on the way from device to skin, a potential downside of the MMSphere design.

“This is a tremendously undertapped area in medicine,” he said. “But LED light therapy is going to revolutionize the way home medical treatment is delivered for skin care over the next 10 to 15 years.”

Kaiyan Medical

In Kaiyan Medical you can create your own LED facial mask. We have developed Aduro mask who is one of the top facial masks in the beauty industry. Julia Roberts is a big fan of Aduro Mask. For more information visit https://www.aduroled.com/