Beard Growth & Light Therapy

Beard Growth & Light Therapy

“The benefit of having a beard is protection, as well as aesthetics,” says Dave Harvey, M.D. “It's good protection against wind, chafing, and traumatic injury. It’s also a trend, so we see a lot of men with some form of facial hair.”

The Health Benefits of Beards

Beards can:

  • Protect skin from sun damage. Beards can help protect the skin from harmful UV rays, though the degree of protection may depend on hair density and thickness. “You’re going to have some protection because hair is a reflective medium,” says Dr. Harvey. “Even though some UV rays get through, there is some scattering of the light, and that’s how it helps protect against sun damage.”
  • Keep you warm. Beards can add a layer of protection to your chin and neck, thus keeping you warm in colder weather. The longer and fuller the beard, the better it will insulate your face.
  • Make you feel more attractive. A study conducted by the Official Journal of the Human Behavior and Evolution Society found that men with a moderately full beard are most attractive. Men with full beards may be perceived as better fathers who could protect and invest in their children. “Men with beards have a powerful look,” says Dr. Harvey. “And that’s an attractive thing.”

Common Problems for Beard Growers

Growing a beard is not always easy. And if your beard is not properly cared for, it can become a harbinger for bacteria.

“If you don’t clean your beard well, and you let it just do its own thing, sometimes you can accumulate yeast and get dandruff within the beard,” says Dr. Harvey. “With that, you’ll get a reactive scaling on the face and flaking like you would with dandruff. So those patients need to be put on antifungal shampoo.”

Beard growers also face the challenge of ingrown follicles that result in bumps known as acne keloidalis.

“Some men will get a raised scarring type of bump called an acne keloidalis of the neck,” he says. “So we offer them topical antibiotics or Retin A for those particular reasons.”

Low-Level Laser Therapy for Beards

Low-level laser therapy (LLLT) is an FDA-approved treatment using laser light energy to circulate blood flow to hair follicles. Laser therapy for hair growth can be used to stop hair loss in men and women. The non-invasive lasers stimulate hair follicles to induce regrowth, resulting in a thicker beard in several weeks of treatments.

Laser hair therapy is also called red light therapy. The process irradiates photons in skin tissue, resulting in photons being absorbed into weaker hair follicles and promoting hair growth.

How Successful Is Laser Hair Restoration?

Laser treatment for hair loss works because photons amp up circulation and stimulation, which brings back hair follicles that may have died off.

Clinical Study

Laser hair restoration therapy is continuing to develop. Still, the National Institutes of Health has conducted multiple studies on laser hair growth therapy to see if it works for those with alopecia and male pattern baldness.

The NIH study used a controlled clinical trial that found laser hair therapy works for men and women, and it’s safe.

Another study from 2013 included male participants aged 18 to 48. The result of laser hair therapy treatment included a 39 percent increase in hair growth for participants over four months.

However, laser therapy is just one piece of the puzzle. Many factors contribute to repeated hair loss, including:

  • Age.
  • Genetics.
  • Medical conditions like diabetes and lupus.
  • Hormones.
  • Poor diet.
  • Side effects of medications, such as chemotherapy.
  • Stress.

How Long Does Laser Hair Therapy Take To Work?

From your first treatment, it can take several weeks to see a noticeable difference. This is because red light therapy for hair loss must be administered multiple times over 4 to 6 weeks to begin working.

If you don’t see any growth after 90 days, it’s probably unlikely you’ll regrow hair with this method. You should consult your doctor about the growth cycle and see how long it will take.

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Light Therapy & Sleep Quality: The Secret of the Chinese Female Basketball Players

Good sleep is a prerequisite for optimal performance. Given that people spend about one-third of their lives asleep, sleep has substantial development, daily functioning, and health. Perhaps no daytime behavior has been associated more closely with improved sleep than exercise. Researchers have shown that exercise serves as a positive function for sleep. Regular exercise consistently has been associated with better sleep. Moreover, the American Academy of Sleep Medicine considers physical exercise a modality of nonpharmacologic treatment for sleep disorders. When studying the influence of exercise on sleep, most investigators have compared acute and sedentary control treatments. In the study of regular moderate-intensity endurance exercise, researchers also provided compelling evidence that exercise promotes sleep.

However, exercise can negatively affect sleep quality. Exercising immediately before going to sleep is detrimental to sleep quality. Athletes train very hard to improve their on-field performances, but excessive training may decrease performance, known as overtraining syndrome. Researchers have shown that symptoms of overtraining indicate poor-quality sleep. Good sleep is an important recovery method for the prevention and treatment of overtraining in sports practice.

In a recent study in which red-light therapy (wavelength = 670 nm, light dose = 4 J/cm2) was used, researchers indicated that red light could restore glutathione redox balance upon toxicologic insult enhance both cytochrome c oxidase and energy production, all of which may be affected by melatonin. Melatonin is a neurohormone that is produced by the pineal gland and regulates sleep and circadian functions. No one knows whether sleep is regulated by melatonin after red-light irradiation in athletes. Researchers have demonstrated that phototherapy improves muscle regeneration after exercise. A red light could protect human erythrocytes in preserved diluted whole blood from the damage caused by experimental artificial heart-lung machines.

Participants

Twenty female athletes of the Chinese People’s Liberation Army team (age = 18.60 ± 3.60 years) participated in the study. All participants were healthy and were not using medications regularly or temporarily during the measurements. Athletes were excluded if they had participated in less than 80% of the scheduled team physical training and basketball sessions for the last 3 months or used any nutritional supplements or pharmacologic agents. All participants provided written informed consent, and the Ethical Committee approved the China Institute of Sport Science study.

Design

Participants were assigned randomly to either a red-light therapy intervention group (n = 10) or non–red-light therapy intervention group (placebo group, n = 10). Measurements were collected at preintervention (baseline) and postintervention (14 days). The exercise training schedule of the 2 groups was unchanged during the 14 days; the red-light treatment group used a red-light therapy instrument every night for total body irradiation for 30 minutes. The training routine of the athletes during the 14 intervention days included 12 exercise sessions with the following specifications: 2 hours of morning training, 2 hours of afternoon training, and no training on Sunday.

The red-light treatment participants lay in the supine position. Continuous illumination was performed using noncoherent red light from a whole-body red-light treatment machine-like Kaiyan’s red light therapy bed, with an average wavelength of 658 nm and a light dose of 30 J/cm2. The whole body received the phototherapy treatment. The placebo participants also lay in the supine position under the red-light device but did not receive any light illumination. All participants wore swimsuits to enhance irradiation from the device and were blind to the treatment.


Measurement

Sleep Quality

The Chinese version of the PSQI measured sleep quality. The 19-item measure assesses sleep quality and disturbances over a half-month time interval. The total PSQI score ranges from 0 to 21, and higher scores reflect poorer-quality sleep. The 7 items of this instrument measure several aspects of insomnia: difficulties with onset and maintenance of sleep, satisfaction with the current sleep pattern, interference with daily functioning, noticeable impairment attributed to sleep problems, degree of distress, and concern caused by any sleeping problems.

Cooper 12-Minute Run

Participants were instructed to complete as many laps as possible on a 400-m outdoor track during the 12-minute test period. Emphasis was placed on pacing oneself throughout the test. The test administrators counted the laps completed during the 12-minute test period while calling out the time elapsed at 3, 6, and 9 minutes and orally encouraging the participants. At the end of the 12-minute period, the test administrator instructed the participants to stop and used a measuring wheel to determine the fraction of the last lap completed by each participant. This distance was added to the distance determined by the number of laps completed to give the total distance covered during the test.

Serum Melatonin

In humans, the serum level of melatonin, derived mainly from the pineal gland, demonstrates a clear increase at night and a decrease during the day. Given that the masking effects of activities (e.g., exercise, sleep, and food intake) have little effect on the circulating melatonin level's daily pattern, melatonin secretion appears to directly reflect the function of the biological clock as a specific marker of the circadian rhythm.

Conclusions

The study has demonstrated that red-light illumination positively affected sleep quality and endurance performance variables in Chinese female basketball players. Based on previous studies, we can infer that red-light treatment contributes to increased melatonin secretion in the pineal gland and muscle regeneration. Although more studies involving phototherapy, sleep, and exercise performance need to be performed, red-light treatment is a possible nonpharmacologic and noninvasive therapy to prevent sleep disorders after training.

Acknowledgments

This research project was supported by the National Key Technologies R&D Program Fund of China (2006BAK37B06).

Originally from:


Red Light and the Sleep Quality and Endurance Performance of Chinese Female Basketball Players

Jiexiu Zhao, Ye Tian, Jinlei Nie, Jincheng Xu, Dongsen Liu

J Athl Train. 2012 Nov-Dec; 47(6): 673–678. doi: 10.4085/1062-6050-47.6.08

PMCID: PMC3499892

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Neonatal Care Taps into Light Therapy

When a baby is born, all parents hope for a healthy child—all ten fingers and toes, a strong heart, and an able body. However, between 10 and 15 percent of babies born within the U.S. require special care within the NICU (Neonatal Intensive Care Unit), which is where preterm or diseased babies are cared for. 

This time is crucial for babies; it's the stage in which we, as humans, are most sensitive. After the first hour of life, newborns should receive eye care, vitamin K, and recommended immunizations (birth dose of OPV and Hepatitis B vaccine). They should be assessed for birth weight, fetal age, congenital disabilities, and newborn illness signs. Special care is provided for sick newborns, preterm and/or low birth weight, and babies exposed or infected by HIV or have congenital syphilis.

One of the more common diseases for premature babies is jaundice, which refers to the yellowish discoloration of the skin, sclerae, and mucous membranes caused by an increase in bilirubin in the blood. This substance derives from the metabolism of hemoglobin contained in red blood cells. For the newborn, it is (in most cases) destined to disappear within a few days.

Jaundice becomes evident when the amount of bilirubin exceeds 3 mg per deciliter. The yellowish color occurs first in the face and sclerae (the white part of the eye) and then extends to the trunk and upper and lower limbs. Jaundice can be physiological or indicate a pathology.

However, jaundice can become severe. This happens when it goes untreated for too long, it can cause a condition called kernicterus. Kernicterus is a type of brain damage resulting from high levels of bilirubin in a baby's blood. It can cause cerebral palsy and hearing loss.

Babies are naturally sensitive, and premature newborns are even more at risk. Their immune systems are still developing due to being born prematurely, which increases their risk of getting sick. Skin conditions of many kinds are common; in addition to jaundice, many experience feeding issues, and fever (always the first sign of an infection). 

Due to the nature of premature babies, it's essential to consider a non-invasive, non-medical treatment. They're still growing, just fully coming into their own and catching up on time missed developing in mom’s belly. 

Light therapy is an incredible tool for these little humans, working inward and targeting the cellular level. It helps with both external and internal problems, which means that at the cellular level, light therapy alters and enhances the cell constitution. This, as a result, leads to faster and better reproduction, creating a healthier and stronger organism and body to function with. 

Light therapy is a non-invasive, non-pharmaceutical form of therapy. The way it can help with neonatal care is unique. During treatments, the babies are completely safe and protected, with their eyes covered. The skin gets exposed to the light therapy lamp to absorb its benefits. The lamp is positioned specifically for the baby, no closer than 30.5cm. 

Light therapy has successfully treated newborn jaundice by lowering the bilirubin levels in the baby's blood through a process called photo-oxidation. Photo-oxidation adds oxygen to the bilirubin, making it dissolve in water easily. 

Since light therapy also helps to regulate circadian rhythm and melatonin, the treatments can also help babies sleep, which is essential in their healing and development. 


You can customize and completely control light therapy consumption for babies, thanks to Kaiyan Medical’s state-of-the-art light therapy device manufacturing services. We have been working for 15 years to produce the best light therapy products on the market which are MDA-certified and FDA-approved light therapy devices, many of which are cleared for at-home treatments. Of course, before using a light therapy device, always consult your doctor.

Back to Nature: The Healing Power of Bird Sounds

What is Sound Therapy?

Sound has been used to heal and calm people for thousands of years. Himalayan singing bowls used in Asia during prayer and meditation positively affect one’s health and well-being. This is just one example of age-old instruments from all over the world being applied as healing instruments.

Sound therapy is based on the premise that we are all made up of energy frequencies, and audio frequencies can interact with our body’s energy to rebalance our systems.

Since music is basically just organized sound, it can be deconstructed to affect our physical and psychological well-being positively.

Ailments Sound Therapy can Help:
  • Anxiety
  • Depression
  • Post-traumatic stress disorder
  • Autism and learning disabilities
  • Dementia
  • Behavior and psychiatric disorders
Five Other Benefits of Sound Therapy
  • Lower stress responses
  • A decrease in mood swings
  • Pain management
  • Improves sleep
  • Lowers blood pressure

How Does Bird Music Help in Sound Therapy?

Our body’s response to noise traces back to when humans began roaming the earth. Think about loud noises  such as your alarm clock in the morning, the rattling of a jackhammer, or the din of the open office. These sounds evoke an instinctive fight-or-flight reaction in our brains, causing a release of chemicals that stimulates immediate action. This reaction has been instrumental to our survival for eons and remains so to this day. The loud honk of a car horn immediately stimulates our brain and body to respond quickly and get us out of harm’s way.

The things we see, hear, and experience moment after moment not only change our mood but impact us on a deeper physical level; it alters the way our nervous, endocrine, and immune systems function.

Listening to birdsong is a wonderful way to reconnect with nature and shift your focus away from the clutter and chaos that is often part of our daily lives.

According to Eleanor Ratcliffe from the University of Surrey, in her thesis examining the restorative perceptions and outcomes associated with listening to birds, bird sounds have the ability to transport yours to nature.

So, not only does bird music affect us positively on a fundamental level of sound frequency, but it also has the capability to make you think you’re in a natural environment, which will in and of itself reduce stress, anxiety, and depression.

Why Is Bird Music So Powerful For Relaxation And Reducing Anxiety?

In today’s fast-paced world, it is vital to make lifestyle choices that will reduce stress and ultimately prolong your life. It has been revealed that listening to slow tempo, low-pitched music with no lyrics can reduce stress and anxiety in people who are to undergo invasive surgery. It also lessens the requirement of subsequent pain medication.

Now, the above are some proven benefits of listening to ordinary music. Just think how powerful it will be to add bird sounds to the mix?

Bird songs and calls are the sorts of natural sounds that most people associate with perceived stress recovery.

During semi-structured interviews conducted with twenty adult participants, Eleanor Ratcliffe determined the following reasons why bird song helps with relaxation and reducing anxiety.

1. Invokes Positive Memories

Bird sounds associated with enjoyable or special events help combat stress and anxiety and ease depressive episodes, as it creates positive emotions linked with particular places and times.

2. Shifts the Focus

Listening to bird music during trying times moves the focus away from the problems and leads to calm.

3. Change of Stimuli

We get used to the everyday sounds of city life. When we listen to bird music, it provides a break from the emotions associated with our surroundings. This short reprieve will help reduce stress.

4. Welcome Distraction

Bird music has the ability to effortlessly take you out of your current environment without you having to move a muscle.

As a symbol of nature, a bird song transports you far from the daily hustle and bustle and removes you from day-to-day demands that may be causing anxiety.

Although science hasn’t yet caught up with bird music believers’ confidence in its healing properties, the evidence speaks for itself since most support is anecdotal.

Bird music is by no means a miracle cure and should still be used in conjunction with medicine as prescribed by your general practitioner.

How Does Bird Music Work Scientifically?

Bird music can clearly have positive effects on a person’s mood, mental health, and physical well-being.

But what real scientific proof is there of music in general’s impact on mental states?

Below you will find some studies that back up what people have been saying for years — music has healing properties.

1. Changes Brain Function

Using electroencephalographs (EEGs) — a device that measures electrical impulses in the brain — established that music with a strong beat stimulates the brain. In contrast, slow beats encourage the brain to relax by promoting a meditative state. When you listen to faster beats, it can lead to deep concentration.

According to a psychologist who was one of the participating researchers, the human brain is usually locked into a specific functioning level. But by speeding up or slowing down the brainwaves, it is easier for the brain to change its speed in reaction to external and internal stimuli.

2. It Increases Blood Flow in the Brain

Thomas Budzynski, an affiliate professor of psychology at the University of Washington, found that the mind enjoys new stimuli. Whenever the brain experiences new sights or sounds, blood flow increases, equalling a better cognitive response. Some anecdotal evidence indicates that this increase in blood flow may help in repairing damaged brain cells.

3. Stimulates the Release of Internal Opioid Peptides

In a review titled The Neurochemistry of music, it is mentioned that listening to music lowers the need for pain medication due to the euphoria often experienced when listening to specific music.

4. Increases Dopamine Levels

Dopamine is responsible for body movements but also plays a role in a person’s emotional response. For this reason, should music raise dopamine, it will be an excellent thing, especially if you’re suffering from mood swings, depression, anxiety, and other mental illnesses or associated symptoms.

Using neuroimaging technology, the central dopamine release while listening to enjoyable music was measured, and the results are positive. The right type of music does increase dopamine.

No wonder listening to music is one of life’s most pleasurable and relaxing activities.

Kaiyan Medical

We are pioneers and architects of light therapy products. Slowly, we are implementing sounds into our devices. We no longer design for our skin and muscles but also our ears.

Beard Growth & Light Therapy

Beard Growth & Light Therapy

“The benefit of having a beard is protection, as well as aesthetics,” says Dave Harvey, M.D. “It's good protection against wind, chafing, and traumatic injury. It’s also a trend, so we see a lot of men with some form of facial hair.”

The Health Benefits of Beards

Beards can:

  • Protect skin from sun damage. Beards can help protect the skin from harmful UV rays, though the degree of protection may depend on hair density and thickness. “You’re going to have some protection because hair is a reflective medium,” says Dr. Harvey. “Even though some UV rays get through, there is some scattering of the light, and that’s how it helps protect against sun damage.”
  • Keep you warm. Beards can add a layer of protection to your chin and neck, thus keeping you warm in colder weather. The longer and fuller the beard, the better it will insulate your face.
  • Make you feel more attractive. A study conducted by the Official Journal of the Human Behavior and Evolution Society found that men with a moderately full beard are most attractive. Men with full beards may be perceived as better fathers who could protect and invest in their children. “Men with beards have a powerful look,” says Dr. Harvey. “And that’s an attractive thing.”

Common Problems for Beard Growers

Growing a beard is not always easy. And if your beard is not properly cared for, it can become a harbinger for bacteria.

“If you don’t clean your beard well, and you let it just do its own thing, sometimes you can accumulate yeast and get dandruff within the beard,” says Dr. Harvey. “With that, you’ll get a reactive scaling on the face and flaking like you would with dandruff. So those patients need to be put on antifungal shampoo.”

Beard growers also face the challenge of ingrown follicles that result in bumps known as acne keloidalis.

“Some men will get a raised scarring type of bump called an acne keloidalis of the neck,” he says. “So we offer them topical antibiotics or Retin A for those particular reasons.”

Low-Level Laser Therapy for Beards

Low-level laser therapy (LLLT) is an FDA-approved treatment using laser light energy to circulate blood flow to hair follicles. Laser therapy for hair growth can be used to stop hair loss in men and women. The non-invasive lasers stimulate hair follicles to induce regrowth, resulting in a thicker beard in several weeks of treatments.

Laser hair therapy is also called red light therapy. The process irradiates photons in skin tissue, resulting in photons being absorbed into weaker hair follicles and promoting hair growth.

How Successful Is Laser Hair Restoration?

Laser treatment for hair loss works because photons amp up circulation and stimulation, which brings back hair follicles that may have died off.

Clinical Study

Laser hair restoration therapy is continuing to develop. Still, the National Institutes of Health has conducted multiple studies on laser hair growth therapy to see if it works for those with alopecia and male pattern baldness.

The NIH study used a controlled clinical trial that found laser hair therapy works for men and women, and it’s safe.

Another study from 2013 included male participants aged 18 to 48. The result of laser hair therapy treatment included a 39 percent increase in hair growth for participants over four months.

However, laser therapy is just one piece of the puzzle. Many factors contribute to repeated hair loss, including:

  • Age.
  • Genetics.
  • Medical conditions like diabetes and lupus.
  • Hormones.
  • Poor diet.
  • Side effects of medications, such as chemotherapy.
  • Stress.

How Long Does Laser Hair Therapy Take To Work?

From your first treatment, it can take several weeks to see a noticeable difference. This is because red light therapy for hair loss must be administered multiple times over 4 to 6 weeks to begin working.

If you don’t see any growth after 90 days, it’s probably unlikely you’ll regrow hair with this method. You should consult your doctor about the growth cycle and see how long it will take.

Wellness Gurus: Who's Turning to Light Therapy for Full-Body Treatment

Light therapy has many benefits, working from the inside, out. It not only helps with our appearance but also internal wellness — because who said beauty's just skin deep? 

Many people find themselves turning to this new form of treatment since it's non-invasive and comes with long-term positive effects — something most people aren't used to hearing. 

While outwardly, the skin smooths out, pores are reduced, wrinkles diminished, and collagen restored. Inwardly, light therapy works directly with our cells, generating an increase of ATP, the energy that fuels us. 

LED Light Therapy uses color wavelengths of visible light, each with specific skin benefits. Due to sun damage, aging, skin disorders, healthy skin cells are compromised and have a more difficult time renewing themselves normally.

But why are wellness gurus going crazy for light therapy? 

Light therapy is not that new; however, it's been gaining popularity due to its benefits, especially in the wellness industry. While everyone is eager to look younger, going under the knife is very invasive. Light therapy is not only effective and easy to use; it's non-invasive. The device needed for light therapy is usually a lamp or light therapy box. 

Is light therapy good for skin? Absolutely. And one of the best things next to the long-term effects is that light therapy can be used as laser light therapy at home. This is the most comfortable way of having the benefits of light therapy. Many celebrities themselves are opting for this route as opposed to invasive treatments.

Light is used as a source of energy, and our skin soaks it up, turning it into ATP (our life fuel). Cells reproducing faster and more efficiently brings the repair and rejuvenation of damaged cells, or, in the case of treating acne, kill bacteria. This stimulates the production of collagen and elastin, boosts circulation, and accelerates tissue repair. You simply lie underneath a light screen during the treatment while the LED light device.

What can light therapy be used for you may be wondering? It isn't only beneficial for your skin; it works directly within our cells, accelerating ATP production. This makes it helpful with overall health, physical and mental. Light exposure has also been linked to being a trigger of serotonin, the way natural light does as well. Not only does it trigger serotonin, but also melatonin, which helps regulate your sleep cycle. 

Luckily, instead of having to go to a doctor for your treatments, you have your own LED light therapy mask or device in the comfort of your home. Allowing wellness gurus and everyday people to enjoy the benefits of red light therapy. 

Light therapy devices work not only the face but as a full body treatment that can help with muscle tension and fascia. Fascia is the connecting tissue that holds every organ, blood vessel, bone, nerve fiber, and muscle in place.

Gwyneth Paltrow even explores on goop.com the many different appealing sides to it. “Light acts as a mild stressor on the body in a dose-dependent manner. We always consider stress to be a bad thing, but at low levels, stress can be good for us. It conditions our tissues and stimulates endogenous protective responses that prime us for either existing or future insult.”

Kourtney Kardashian has taken her LED light therapy mask to the public as well, promoting the device and its benefits. She enjoys both red and blue light treatments, often posting her with her at-home mask. She’s mentioned retinol use alongside the regular treatments, and other skin rejuvenating products. 

But more and more celebrities and wellness gurus are turning to light therapy for a full body treatment. Jessica Alba, alongside celebrities including Emma Stone, Chrissy Teigen, Lena Dunham, Kelly Rowland, and Real Housewives of New York City’s Carole Radziwill, have openly discussed red light therapy treatment. 

Many top skincare and wellness brands are turning to Kaiyan for their red light therapy device production. And though we produce devices that are incredibly effective, our devices are also MDA-certified and FDA-approved, giving you security in knowing your devices not only are effective but are safe. 

Injecting UV Light? - Ultraviolet blood irradiation (UBI)

Ultraviolet blood irradiation (UBI) was extensively used in the 1940s and 1950s to treat many diseases, including septicemia, pneumonia, tuberculosis, arthritis, asthma, and even poliomyelitis. The early studies were carried out by several physicians in the USA and published in the American Journal of Surgery. However, with the development of antibiotics, UBI use declined, and it has now been called “the cure that time forgot.” Russian workers and other Eastern countries mostly performed later studies, and the modern view in Western countries is that UBI remains highly controversial.

No resistance of microorganisms to UV irradiation has been reported, and multi- antibiotic-resistant strains are as susceptible as their wild-type counterparts. Low and mild UV kill microorganisms by damaging the DNA, while DNA repair enzymes can rapidly repair any DNA damage in host cells. However, UBI treats septicemia cannot be solely due to UV-mediated killing of bacteria in the blood-stream, as only 5–7% of blood volume needs to be treated with UV to produce the optimum benefit. UBI may enhance the phagocytic capacity of various phagocytic cells (neutrophils and dendritic cells), inhibit lymphocytes, and oxidize blood lipids. The oxidative nature of UBI may have mechanisms in common with ozone therapy and other oxygen therapies.

Ultraviolet (UV)

Ultraviolet (UV) radiation is part of the electromagnetic spectrum with a wavelength range (100–400 nm) shorter than that of visible light (400–700 nm) but longer than x-rays (<100 nm). UV radiation is divided into four distinct spectral areas, including vacuum UV (100–200 nm), UVC (200–280 nm), UVB (280–315 nm), and UVA (315–400 nm). Only part of UVB and UVA can reach on earth because wavelengths shorter than 280 nm are filtered out by the atmosphere, especially by the “ozone layer.”

In the second half of the nineteenth century, the therapeutic application of sunlight known as heliotherapy gradually became popular. In 1855, Rikli from Switzerland opened a thermal station in Veldes in Slovenia to provide helio-therapy. In 1877, Downes and Blunt discovered by chance that sunlight could kill bacteria. They noted that sugar water placed on a window-sill turned cloudy in the shade but remained clear while in the sun. Upon microscopic examination of the two solutions, they realized that bacteria were growing in the shaded solution but not in the one exposed to sunlight.

Emmett K Knott in Seattle, WA, reasoned that the beneficial effects of UV irradiation to the skin obtained by Ude might be explained by the irradiation of blood circulating in the superficial capillaries of the skin. With his collaborator Edblom, an irradiation chamber was constructed to allow direct blood exposure to UV. The irradiation chamber was circular and contained a labyrinthine set of channels that connected the inlet and outlet ports. All these channels were covered with a quartz window that formed the top of the chamber. The irradiation chamber was designed to provide maximum turbulence of the blood flowing through. This was done to (a) prevent the formation of a thin film of blood on the chamber window that would absorb and filter out much of the UV light; (b) ensure that all the blood passing through the chamber was equally exposed to UV.

Mechanisms of Action of UBI

One of the major obstacles that UBI has consistently faced throughout the almost 90 years since the first patient was treated has been the lack of understanding of action mechanisms. Over the years, its acceptance by the broad medical community has been hindered by this uncertainty. Confusion has been caused by the widely held idea that since UV is used for sterilization of water and surgical instruments; therefore its use against infection must also rely on UV-mediated direct destruction of pathogens. Another highly confusing aspect is the wide assortment of diseases, which have been claimed to be successfully treated by UBI. It is often thought that something that appears to be “too good to be true” usually is.

UBI affects various functions of red blood cells and various leukocytes, as proven in various in vitro studies. A common model is stimulator cells in mixed leukocyte cultures; another is helper cells in mitogen-stimulated cultures. UV also reversed cytokine production and blocked cytokine release. UV can also disturb cell membrane mobilization.

Effects on Red Blood Cells

Anaerobic conditions strongly inhibited the process by which long-wave UV light induces the loss of K+ ions from red blood cells. Has been proved that UV-irradiation could affect the osmotic properties of red blood cells, the submicroscopic structure, and adenine nucleotides' metabolism. Irradiation times (60, 120, 180, 240, and 300 minutes) were used; during the irradiation, ATP decreased while the amounts of ADP, AXP, and adenine compounds increased. UV also increased hypotonic Na +, and K+ ion exchange and the hematocrit value increased.

A two-phase polymer system containing poly-dextran was used to show that circulating erythrocytes' cell surface was reduced after UV irradiation. This contributed to the prolongation of survival of transfused erythrocytes and was suggested to explain the more effective therapeutic activity of autotransfusion blood.

Effects on Lymphocytes (T-Cells and B-Cells)

UBI generally decreases lymphocyte viability. UVC irradiation is the most effective among the three UV spectral regions. UVB and UVC irradiation can abolish the proliferative and stimulatory ability and the accessory/ antigen-presenting ability of lymphocytes in vitro. The cell-surface properties, calcium mobilization, cytokine production and release, and other sub-cellular processes could all be changed by UV irradiation. Areltt et al. used the “Comet “assay to detect DNA-strand breakage (single-cell gel electrophoresis) as an indicator of excision repair to prove that circulating human T–lymphocytes were exquisitely hyper-sensitive to the DNA-damaging and lethal effects of UV-B radiation, raising the possibility that UV-B may contribute to immunosuppression via a direct effect on extra capillary T-lymphocytes.

Effects on Platelets

H2O2 production in platelets is low at a shallow UV dose, but it increased suddenly as the dose increased above 0.4 J/cm2. Pamphilon reported that platelet concentrates (PC) could become non-immunogenic after UVR and after being stored for 5 days in DuPont Stericell containers. Lactate levels, β-thrombomodulin, and platelet factor were higher after UV. In contrast, glucose levels decreased with an irradiation dose of 3000 J/m2 at a mean wavelength of 310 nm applied in DuPont Stericell bags. Ultraviolet B (UVB) irradiation of platelet concentrate (PC) accelerated downregulation of CD14 and nonspecifically increased the loss of monocytes by inhibiting the upregulation of ICAM-1 and HLA-DR. However, UV irradiation of platelet concentrates produced a reduction of immunological response in a cell suspension.

Things to consider before buying a UVC device

There are a few things you should consider before investing in a UVC wand or other UVC devices.

The first and most important thing to consider: safety. Experts have said UVC can affect skin cells the same way it kills bacteria; it can cause mutations in them and lead to skin cancer. Looking at UVC lights can cause irreversible blindness, too.

Here in Kaiyan Medical, we suggest that you look for UVC devices that come with safety switches — automatic “turn-off” buttons that halt the light emission as soon as you’re at risk of direct exposure.

The second thing to consider: the legitimacy of the product. We have seen some counterfeit UVC consumer products on the market. But unless you have a device at home that measures wavelength in realtime (aka a spectrometer), there’s no way of distinguishing products that use UVC rays versus other UV rays.

Conclusion

UV irradiation of blood was hailed as a miracle therapy for treating serious infections in the 1940s and 1950s. In an ironic quirk of fate, this historical time period coincided with the widespread introduction of penicillin antibiotics, which were rapidly found to be an even bigger medical miracle therapy. Moreover, another major success of UBI, which was becoming increasingly used to treat polio, was also eclipsed by the introduction of the Salk polio vaccine in 1955. UBI had originally been an American discovery but then was transitioned to being more studied in Russia and other eastern countries, which had long concentrated on physical therapies for many diseases, which were more usually treated with drugs in the West.

However, in the last decade, the problem of multi-antibiotic-resistant bacteria has grown relentlessly. Multidrug-resistant (MDR) and pan drug-resistant (PDR) bacterial strains and their related infections are emerging threats to public health throughout the world. These are associated with approximately two-fold higher mortality rates and considerably prolonged hospital admissions. The infections caused by antibiotic-resistant strains are often tough to treat due to the limited therapeutic options range. Recently in Feb 2015, the Review on Antimicrobial Resistance stated, “Drug-resistant infections could kill an extra 10 million people across the world every year by 2050 if they are not tackled. By this date, they could also cost the world around $100 trillion in the lost output: more than the size of the current world economy, and roughly equivalent to the world losing the output of the UK economy every year, for 35 years”.

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SAD - Seasonal Affective Disorder 101

The first formal description of Seasonal Affective Disorder (SAD), the most well-known psychiatric condition associated with seasonality in humans, was introduced in the mid-1980s by Rosenthal, who described a group of 29 patients living in a temperate climate who experienced depressive episodes characterized by hypersomnia, hyperphagia, and weight gain in the fall or winter, and whose symptoms remitted by the next spring or summer.

SAD was incorporated into the Diagnostic and Statistical Manual (DSM) of Mental Disorders III-R when “seasonal pattern” was introduced as a specifier for Major Depression and Bipolar Disorders. Subsequent revision in DSM-IV described SAD as “a regular temporal relationship between the onset of Major Depressive Episodes in Bipolar I (BPI) or Bipolar II (BPII) Disorder or Major Depressive Disorder (MDD), recurrent, and a particular time of the year.”

Today, SAD, or MDD with seasonal pattern, is defined as recurrent episodes of major depression that meet the following criteria: at least two consecutive years where the onset and offset of depressive symptoms occur at characteristic times with no non-seasonal episodes, a temporal relationship between onset of symptoms and time of year, a temporal relationship between remission of symptoms and time of year, and an outnumbering of seasonal compared to non-seasonal episodes throughout the lifetime of the patient.

Pathophysiology of SAD

To date, the pathophysiology of SAD is unclear. Early research into the mechanism of SAD focused on day length or photoperiod. This hypothesis posited that shorter days in winter, possibly mediated by a longer duration of nocturnal melatonin secretion, leads to depressed mood in susceptible individuals. To date, there is little data to support this hypothesis. Furthermore, given that bright light in the evening has not been as effective as that given in the morning, it now seems unlikely that the photoperiod is the underlying pathological mechanism of SAD.

Although some animal studies have implicated a direct effect of light on the midbrain (Miller, Miller, Obermeyer, Behan, & Benca, 1999; Miller, Obermeyer, Behan, & Benca, 1998), the most prominent hypothesis driving human studies involves disruption of circadian rhythms. Research on the role of serotonin is also active.

Circadian Rhythm

A circadian rhythm refers to the approximately 24-hour cycle of physiological processes present in humans and other animals. This cycle is governed via clock gene expression by the suprachiasmatic nucleus (SCN), the master pacemaker located within the anterior hypothalamus. Though the SCN endogenously generates circadian oscillations, SCN endogenously generates circadian oscillations, and they need to be entrained to the 24-hour day by external cues. Light exposure is the most important synchronizing agent of endogenous circadian rhythms.

Downstream of the SCN, a collection of systemically active neurohumoral networks transduce circadian information to the rest of the body. For instance, via projections to the hypothalamus's paraventricular nucleus, the activation of the SCN leads to autonomic changes, including cardiovascular modulation, and together the central, peripheral, and autonomic nervous systems collaborate to affect systemic changes. Thus, the SCN receives information about the external day-night cycle directly through retinofugal pathways and indirectly through neuromodulatory signaling. Circadian information is then relayed systemically through neurohumoral networks.

The current primary hypothesis for the pathophysiology of SAD, known as the “phase-shift hypothesis,” posits that there is an optimal relationship in the alignment of the sleep-wake cycle and the endogenous circadian rhythm. During the fall and winter, as day length shortens, the circadian rhythm begins to drift later concerning clock time and the sleep-wake cycle. This phase delay is hypothesized to bring about mood symptoms. A pulse of morning bright light generates a circadian phase advance, which is thought to correct the discordance between sleep and circadian phase, thereby ameliorating depressive symptoms. However, the phase-shift hypothesis would predict that the amount of phase correction required for each patient would depend on an individual’s PAD, which has not yet been proven.

Serotonin

Several studies have also proposed that serotonin is implicated in the pathophysiology of SAD, as selective serotonin reuptake inhibitors (SSRIs) appear to be effective in the treatment of SAD. Supporting this hypothesis, one study used Positron Emission Tomography (PET) imaging to look at binding probability at synaptic serotonin transporters in 88 normal individuals living in the temperate climate of Toronto, Canada (Praschak-Rieder, Willeit, Wilson, Houle, & Meyer, 2008). The binding probability was increased during fall and winter compared to warmer months, thus eliciting an inverse correlation between binding potential and sunlight durationsunlight duration. Of note, the largest difference in transporter binding was found in the mesencephalon, a finding consistent with animal studies demonstrating the importance of direct effects of light to the midbrain on behavior. If increased transporter activity indicated greater reuptake of serotonin during the fall/winter, and if this resulted in a lower density of cleft serotonin, then the seasonal variation in transporter activity (i.e., higher transporter efficiency in the winter) would seem to leave susceptible individuals particularly prone to mood symptoms during the darker seasons. Moreover, following BLT and during periods of remission in the summer months, the synaptic transporter activity was shown to be reduced to control levels in these patients.

Eating Disorders

BLT has also been investigated to a lesser extent in eating disorders. Because binge eating episodes have been observed to increase in fall and winter in some patients, BLT has been examined as a treatment modality for anorexia nervosa (AN) and bulimia nervosa (BN). Thus, BLT's effects on patients with eating disorders remain enigmatic. Additional studies, including larger, randomized, blinded, and controlled trials, are needed to elucidate further the role of BLT in treating this patient population. Further research might also determine whether BLT would be a useful treatment in Binge-Eating Disorder, a diagnosis new to DSM-5.

Adult ADHD

Additionally, BLT has been studied in the context of adult Attention-Deficit/Hyperactivity Disorder (ADHD), where, in addition to normal ADHD symptoms, patients often have depressed mood and difficulties falling asleep, awakening on time, and maintaining arousal (Brown & McMullen, 2001). These symptoms are indicative of a possible delay in the circadian rhythm. A case report of symptom improvement following BLT in a child with ADHD who displayed signs of delayed sleep phase also supports the idea that BLT may be useful in treating symptoms of ADHD (Gruber, Grizenko, & Joober, 2007). Whether the pathways that subserve the improvement of mood symptoms in response to BLT are the same pathways that underlie the seemingly beneficial effects of BLT in ADHD remains to be studied. While these results are promising, further studies, preferably in randomized, blinded, and controlled studies will need to be performed.

Finally

A significant immediate reduction of depression scores with light treatment can be identified after 20 minutes and reaches the maximum at 40 minutes, with no additional benefit at 60 minutes. The rate of change is steepest during the first 20 minutes of light as compared with longer intervals. Comparing the clinical impact of these durations of administration may yield different results when measured after several daily sessions. The overnight effect on circadian rhythms and sleep was not assessed in our study and is thought to impact mood regulation in SAD. Larger, prospective, controlled, and hypothesis-driven studies in more naturalistic conditions would be desirable to replicate our study results and our study results and analyze the temporal dynamic of the persistence of the immediate mood-improvement effects. Besides, in larger samples, one could define early responders and nonresponders, analyze genetic (e.g., melanopsin related genes), demographic (children, adolescents, adults, elderly, gender), physiological (e.g., pupillary responses), and clinical (e.g., abundant atypical symptoms) predictors for early response. If proven effective and efficacious, shorter exposures to bright light could become a feasible and broadly employed intervention for immediate mood improvement as an early step on the road toward full antidepressant response and remission.


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Dreaming of Light Therapy

Light therapy is beneficial for more than just one problem. Rather, it’s an all-in-one health and wellness treatment. It helps with skincare issues ranging from acne to wrinkles to eczema by supporting the mitochondria, which in return provokes better cell production within the body and targeted areas. 

But another thing light therapy is proving to be powerful with is sleep. Sleeping disorders are more frequent than ever, with many people experiencing sleep disorders and, if not full disorder, struggle with achieving restful sleep. 

Stress and anxiety build up through the day, and our addiction to our devices greatly disturbs our sleeping habits. However, a good night’s sleep is actually one of the most important things to maintain if you want optimal health.

While there are many types of sleep disorders—insomnia, sleep apnea, restless legs syndrome (RLS), and narcolepsy—bright light therapy has proven to help reduce many of these conditions. In addition, its effects are also being studied on how they can help with Parkinson’s disease. 

Sleep onset insomnia is one of the things light therapy can effectively treat. Insomnia is the inability to fall asleep at a normal time. Though there are various reasons for insomnia, one problem stems from the advanced or delayed circadian rhythms.

There’s also advanced sleep phase disorder when you tend to feel sleepy in the late afternoon or early evening. Bedtime typically happens between 6 p.m. and 9 p.m. Early bedtime means you often wake up between 2 a.m. and 5 a.m. Light therapy here can help reset your internal clock in the early evening hours.

With delayed sleep phase disorder, you tend to stay up all night or at least a few hours, often past midnight. As a result, you also tend to wake up later in the morning, having lost a good chunk of your day. In this instance, light therapy in the morning, right after you’ve woken up, helps to advance your internal clock and makes you feel sleepy earlier in the evening, helping to adjust to a normal sleeping pattern.

And yet, light therapy treatment is proving to be the perfect solution.

In 2012, Light therapy was studied and found to be an effective nonpharmacological and non-invasive way of treating sleep disorders and improving sleep quality among elite female basketball players. Each participant within the research received14-30 minute light therapy sessions once every night for 14 nights in a row.

Research also showed improved melatonin levels among basketball players, and melatonin is a hormone that promotes sleep. Players in return experienced improved endurance performance. 

In later studies as well, light therapy has proved itself to be very effective. In 2013, a Taiwanese study looked at participants and their electroencephalography (EEG), which means they examined their electrical brain activity. They checked before, during, and after the light therapy simulation. The research suggested that light therapy is beneficial in helping people with sleep disorders. But these are the only studies that show the effectiveness of light therapy.

A study on the cognitive function of people with traumatic brain injury discovered that light therapy helped those people with their cognitive function. Light therapy helped decrease episodes of post-traumatic stress disorder (PTSD). Participants also reported better sleep during the study. 

New research from the University of Arizona Health Sciences discovered that with light therapy, people with migraines have a better chance of improving their sleep, plus act as a preventative measure for future migraines. Patients who were submitted to the research experienced better sleep and fewer headaches with light therapy.

Our minds have been occupied with a lot, with the pandemic, with people experiencing more hardships than before. Even if they’ve gotten used to it, the way of living has drastically changed. It’s no surprise that our sleep has also been affected by this. It’s reported that having bad dreams due to the ongoing pandemic isn’t anything too surprising nor impossible. 

Growing evidence suggests that light therapy can help us improve the ability to fall asleep, remain asleep and get a good night’s all in one. In times when our dreams and sleep are invaded by negative feelings related to any upsetting and unsettling occurrence in our life, light therapy can help us ease our daily stressors and might help us avoid sleep-disturbing dreams.

That said, you want the right light therapy device to help you improve your sleep. Kayian medical produces MDA-certified and FDA-approved light therapy devices to ensure you get the most out of light therapy. 

Follow the Numbers: Light Therapy's Projected Market Revenue Surges

Follow the numbers: light therapy's projected market revenue surges

Light therapy is used for many problems, such as skin conditions, eczema, vitiligo, acne, and rosacea. But it's also very popular as a skincare remedy for wrinkles, age spots, and collagen production.  While helping outwardly, it also works directly with mitochondria, the cells' powerhouse, improving our cell production and increasing cellular function. The non-invasive treatment is gaining popularity for its incredible benefits and cost-effectiveness. 

Light therapy also helps with our lack of vitamin D, and with the current world situation of quarantine and COVID-19, the lack has been more than evident. It helps with psychological conditions that have been rapidly increasing in the past few years, and the current situation only aids in the battle against winter blues and depression. This form of therapy increases melatonin levels and mood levels, helping with fatigue and sleep quality.

Since the market has been affected due to the pandemic, people have been turning to light therapy for its mental and physical benefits. The light therapy market is anticipated to reach 1,112.16 million dollars at a CAGR of 5.1%  by 2025, says Market Research Future (MRFR).

The American market is set to take the lead over in the next few years. Growing international curiosity for light therapy will also help the infrastructure, improve quality with more developers, stimulating substantial market growth. 

For winter blues, light therapy should experience a rise in growth by 5.1% till 2027. Due to less sunlight, light therapy proves as the ultimate fit for those in the Northern Hemisphere. The Asia Pacific light therapy market revenue surpassed USD 175 million in 2018, it is poised to expand at 5.7% CAGR through 2027. Their awareness of the growing patient pool and beauty conscious people fuel the demand for light therapy because of its amazing results in various skin conditions. 

Rising per capita income and the growing influence of social media are opening new avenues for the Asian Pacific market. The demand for light therapy is considerable among people in China and Japan. In addition, its popularity is also rising in developing nations owing to its advanced features and low cost. 

A segment of light therapy specializing in floor and desk lamps of the market was valued at more than 140 million dollars in 2018 and will witness a similar growth trend in the future. Similarly, large reflectors in the floor and desk lamps that diffuse bright light for accurate visualization are predicted to be in higher demand in the upcoming years.

Homecare settings portion had its share of revenue, counting more than 490 million dollars in 2018, and will exhibit a similar rising forecast in the upcoming timeline for light therapy. In 2020 these products held up to 60% of the market share. 

Demand for simplicity and more availability is what allows the rising demand for homecare handheld and user-friendly devices. It's predicted to grow gradually. Manufacturers will focus on developing light therapy devices that specifically solve health-related issues at home by providing easy access and improved patient management. 

North America light therapy market size crossed 350 million dollars in 2020 due to technological advancements paired with light therapy's growing use of light therapy.

Key developers in the U.S. have gained approvals from the FDA for new products, like Kaiyan Medical. With FDA-certified and MDA-approved devices, Kaiyan leads the light therapy devices industry and will continue to play a crucial role for the overall growth in the North American industry.


The Perfect Pair: Light Therapy & PRP

Platelet-Rich Plasma (PRP) Injections

In recent years, doctors have learned that the body has the ability to heal itself. Platelet-rich plasma therapy is a form of regenerative medicine that can harness those abilities and amplify the natural growth factors your body uses to heal tissue.

What is Plasma, and what are Platelets?

Plasma is the liquid portion of whole blood. It is composed largely of water and proteins, and it provides a medium for red blood cells, white blood cells, and platelets to circulate through the body. Platelets, also called thrombocytes, are blood cells that cause blood clots and other necessary growth healing functions. Platelet activation plays a key role in the body’s natural healing process.

What is Platelet-Rich Plasma (PRP), and what are PRP injections?

Platelet-rich plasma (PRP) therapy uses injections of a concentration of a patient’s own platelets to accelerate the healing of injured tendons, ligaments, muscles, and joints. In this way, PRP injections use each patient’s own healing system to improve musculoskeletal problems.

PRP injections are prepared by taking anywhere from one to a few tubes of your own blood and running it through a centrifuge to concentrate the platelets. These activated platelets are then injected directly into your injured or diseased body tissue. This releases growth factors that stimulate and increase the number of reparative cells your body produces.

Ultrasound imaging is sometimes used to guide the injection. The photographs below illustrate a PRP injection into a patient’s torn tendon. The ultrasound guidance is shown at the left, and the injection is shown at the right.

PRP harnesses the body’s own rejuvenating powers to stimulate hair growth naturally. The treatment involves drawing a small amount of blood from the patient’s arm. This blood is then spun in a centrifuge until the plasma is separated and growth factors and stem cells are extracted. This plasma, complete with growth factors and stem cells, is then injected into the patient’s scalp, stimulating hair growth.

Light Therapy

Red Light/Blue Light therapy uses light energy to stimulate hair growth. Red light/Blue Light therapy works using light delivered at specific therapeutic wavelengths within infrared and red-light spectrums. The energy from these lights stimulates the hair follicles so that they are constantly in the growth, or anagen, stage. This results in thicker, longer, and healthier hair.

Red light (630 nm) therapy stimulates ATP (cellular energy) production to stimulate hair follicle cells. It also increases blood flow to the hair root, which delivers more nutrients to the hair follicle cells. The increased blood flow is also thought to help flush away the damaging waste products that may affect hair growth.

Near-Infrared light (880 nm) therapy, which is an invisible light energy, promotes collagen and elastin production. It penetrates deeper into the scalp to help reduce inflammation, which causes thinning of hair.

Blue light (420 nm) therapy is especially effective for acne, penetrating molecules within the skin that cause P. acnes bacteria to form. These molecules react

Creating Your Custom LED Mask

When we talk about skincare, we usually don’t think about customizing skincare products. The options available on the market are produced for the masses rather than for the individual. Many people with multiple skin issues struggle to find skincare products that truly speaks to their needs. However, light therapy masks can be customized to fit the individual customer’s needs.

If you’re working in the skincare industry, light therapy devices are a revolutionary step forward, as you’ll be able to provide your customers with a unique light therapy mask.

But what’s the process of creating a custom light therapy mask? Here are the six steps you need to consider when developing a customized light therapy mask.

The Six Steps to Create Your Custom Led Mask

While going through these six steps, keep your vision of your mask in mind. This will help you answer some of the questions that are going to be asked below.

What’s your Goal?

It would help if you determined your product’s goals. Who are your clients? What are their unique skincare challenges? By understanding the basics, you’ll help your company determine the right strategy when creating your customized product. Light therapy masks can be made using different LED colors for a full range of beauty treatments, including acne reduction, anti-aging treatment, and collagen production.

What Material will you Use?

You need to select the right material. Facial masks can be made from a variety of materials, each with its own advantages and versatility. There are three types of light therapy masks to consider: flexible, semi-hard, and hard.

Flexible allows users to wear it while doing their daily activities. The patented air cushions and emitting SMD LEDs are ideal for indoor and daily skincare. Semi-hard masks are for professional use and have a hard shell, while soft inside. Hard masks are powerful facial masks for professional use and come with selectable light area options. They offer a deeper light therapy experience for clients.

What Kind of Shape will your Mask be in?

Light therapy masks don’t have to come in a traditional one-size-fits-all design. Depending on your target market, you’ll be able to choose where the placement for the cheeks, forehead, and eyes will be on the mask. This gives you more control over how the mask will fit on your client’s face.

What Areas Will your Mask Treat?

A traditional mask will cover the full face. However, you may not necessarily want your mask to provide full coverage. Consider the areas of the face you’d like to treat, as you may only want to create a mask for a specific target area.

Apply for a Prototype

You’ve answered all the questions above and have a vision of how you want your mask to look. From here, we help you take your vision and use our creativity and 14 years of experience in the industry to create a mask that fits your goals.

Launch & Listen

Now that the product is created, it’s time to launch it. Before the launch, we produce pre-pilot quantities that allow us to fine-tune our devices and ensure high-quality from start to finish.

Creating a light therapy facial mask is one thing, but you want to make sure it’s achieving your goals and making your customers happy. Once your product is launched, it’s crucial to monitor product performance and listen to customer feedback.

Naturally, you don’t want your light therapy mask to be like all the others on the market. Our masks are MDA-certified and FDA-approved light therapy devices, ensuring you medical-grade quality devices for your business.


Insomnia & the Dark Side of the Blue Light

Although it is environmentally friendly, blue light can affect your sleep and potentially cause disease. Until the advent of artificial lighting, the sun was the major lighting source, and people spent their evenings in (relative) darkness. Now, in much of the world, evenings are illuminated, and we take our easy access to all those lumens pretty much for granted.

But we may be paying the price for basking in all that light. At night, light throws the body’s biological clock — the circadian rhythm — out of whack. Sleep suffers. Worse, research shows that it may contribute to the causation of cancer, diabetes, heart disease, and obesity.

What is Blue Light?

Not all colors of light have the same effect. Blue wavelengths — which are beneficial during daylight hours because they boost attention, reaction times, and mood — seem to be the most disruptive at night. And the proliferation of electronics with screens and energy-efficient lighting increases our exposure to blue wavelengths, especially after sundown.

Light and Sleep

Everyone has slightly different circadian rhythms, but the average length is 24 and one-quarter hours. The circadian rhythm of people who stay up late is slightly longer, while earlier birds' rhythms fall short of 24 hours. Dr. Charles Czeisler of Harvard Medical School showed, in 1981, that daylight keeps a person’s internal clock aligned with the environment.

Is Nighttime Light Exposure Bad?

Some studies suggest a link between exposure to light at night, such as working the night shift, diabetes, heart disease, and obesity. That’s not proof that nighttime light exposure causes these conditions, nor is it clear why it could be bad for us.

A Harvard study shed a little bit of light on the possible connection to diabetes and possibly obesity. The researchers put 10 people on a schedule that gradually shifted the timing of their circadian rhythms. Their blood sugar levels increased, throwing them into a prediabetic state, and leptin levels, a hormone that leaves people feeling full after a meal, went down.

Exposure to light suppresses the secretion of melatonin, a hormone that influences circadian rhythms. Even dim light can interfere with a person’s circadian rhythm and melatonin secretion. A mere eight lux — a level of brightness exceeded by most table lamps and about twice that of a night light — effects, notes Stephen Lockley, a Harvard sleep researcher. Light at night is part of the reason so many people don’t get enough sleep, says Lockley, and researchers have linked short sleep to increased risk for depression, as well as diabetes and cardiovascular problems.

Effects of Blue Light and Sleep

While light of any kind can suppress melatonin's secretion, blue light at night does so more powerfully. Harvard researchers and their colleagues experimented comparing the effects of 6.5 hours of exposure to blue light to exposure to green light of comparable brightness. The blue light suppressed melatonin for about twice as long as the green light and shifted circadian rhythms by twice as much (3 hours vs. 1.5 hours).

In another blue light study, researchers at the University of Toronto compared the melatonin levels of people exposed to bright indoor light wearing blue-light-blocking goggles to people exposed to regular dim light without wearing goggles. The fact that the hormone levels were about the same in the two groups strengthens the hypothesis that blue light is a potent suppressor of melatonin. It also suggests that shift workers and night owls could protect themselves if they wore eyewear that blocks blue light. Inexpensive sunglasses with orange-tinted lenses block blue light, but they also block other colors, so they’re not suitable for use indoors at night. Glasses that block out only blue light can cost up to $80.

LED Blue Light Exposure

If blue light does have adverse health effects, then environmental concerns, and the quest for energy-efficient lighting, could be at odds with personal health. Those curlicue compact fluorescent lightbulbs and LED lights are much more energy-efficient than the old-fashioned incandescent lightbulbs we grew up with. But they also tend to produce more blue light.

The physics of fluorescent lights can’t be changed, but coatings inside the bulbs can produce a warmer, less blue light. LED lights are more efficient than fluorescent lights, but they also produce a fair amount of light in the blue spectrum. Richard Hansler, a light researcher at John Carroll University in Cleveland, notes that ordinary incandescent lights also produce some blue light, although less than most fluorescent lightbulbs.

Protect Yourself from Blue Light at Night
  • Use any of our red light devices for night lights. Red light is less likely to shift circadian rhythm and suppress melatonin.
  • Avoid looking at bright screens beginning two to three hours before bed.
  • If you work a night shift or use many electronic devices at night, consider wearing blue-blocking glasses or installing an app that filters the blue/green wavelength at night.
  • Expose yourself to lots of bright light during the day, which will boost your ability to sleep at night, as well as your mood and alertness during daylight.

Preparing your Skin for Light Therapy

Can I Use Serum With LED Mask?

It is a question that many people have asked — Can I use the serum with LED light therapy?

Our skin is exposed to harsh environmental factors such as sun, wind, cold, and dust daily. These factors tend to attack our immune system causing it to weaken over time.

When this happens, it allows harmful viruses and bacteria to attack our body, leading to acne breakouts and other skin issues such as dark spots and wrinkles. Acne creams are one way of reducing the symptoms associated with this skin condition. However, these can be irritating to your skin, resulting in unwanted side effects such as redness, irritation, and dryness.

The same can also be said for light therapy, which can have its own side effects. Side effects of LED light therapy include itching, burning, and pain. In fact, most users had reported experiencing these side effects when they first started using LED technology. If you were to use any acne medication type, whether prescribed by your doctor or over the counter, the results would depend largely on the person using the medication.

For example, it could take anything from a few days to a few weeks for acne to clear up. Another point to remember is that while certain medications do show better results for some people, they may not work for you at all.

This is because everyone has different skin types, responds differently to treatments, and requires different times to clear away acne completely.

Some people have found success in using LED therapy with a variety of skin creams. However, there is a downside to using this method. LED light therapy does not help remove excess dead skin cells, as some acne medications do. This means that the acne cream will just be left in place and continue to produce side effects for all patients. Besides, side effects can be more severe than a single acne medication dose when used over a long time when used over a long time.

Before you try to use a serum with an LED mask, you should consult with a dermatologist who can advise you on whether or not LED light therapy is right for you. LED light therapy is safe when administered by a certified medical professional. It can be used safely, even if you have sensitive skin, as long as you choose your doctors wisely. Before any treatment is begun, the medical professional will test your skin to determine what type of acne you have. Testing will determine whether your skin is allergic to any light-emitting diodes in the device used.

The last question to answer is, “How effective is Acne treatment with LED Light?” To answer this question, you will need to look at the results you get from the treatment. If you see immediate results after the treatment, it will likely react to the device's light and not the treatment itself.

However, if you don’t see good results after a month of continuous treatment, it is important to determine why the treatment is not working. It may be that you are allergic to any of the ingredients in the product, or it may be that your skin is not receptive to the treatment.

Hydrated Face For LED Mask Results

The serum is good for hydrated face for LED Mask. It can hydrate the skin by absorbing moisture, providing a slight lift to the skin, and removing any oil or makeup that you are using. The serum also contains vitamins and antioxidants that will help fight against free radicals in your body. Free radicals are harmful agents that have been linked with causing cancer.

By fighting against these harmful agents, Serum is good for hydrated face for LED Mask. People who have used Serum have claimed that the hydrated face and LED Mask work very well together. I have also used Serum on my skin, and I must say that the results were really amazing. In fact, I would go on to say that Serum is so good for hydrated face for LED Mask that I will be using it every single night before bed.

If you don’t have much experience making skin look hydrated, this is the forum for you. Let us first examine the ingredient list of Serum.

This product's main ingredients are Hyaluronic Acid, Vitamin C, Retinol A, Alpha Hydroxy Acids, Vitamin E, DMAE, Peptides, and Glycerin, Ferulic Acid, Aloe Vera.

  • AHA kills the bacteria causing acne and helps to get rid of blackheads.
  • Sodium Laureth Sulfate helps in cleaning the skin by getting rid of dead skin cells and excess oil.
  • Salicylic Acid gets rid of pimples and acne scars, and Glycolic Acid is good in treating acne scars.

All of these ingredients are perfectly good for your hydrated face for LED Mask.

  • Now let us move on to how does Serum works to get rid of the facial puffiness.
  • When you are applying Serum on your hydrated face for LED Mask, you are putting on a layer of serum to the surface of your face.
  • As the serum gets applied, it works its way down into your skin and starts working as a moisturizer.
  • This is why this particular product is top-rated as it works as a good moisturizer without over-drying the skin.
How to Prepare Your Skin For a Red Light Therapy Session?

There are different methods used to prepare your skin, but essentially they all work in the same way: removing all the oil and dirt from the skin and then cleaning it. When I talk about cleansing, I’m talking about daily skincare maintenance products. If you want to know how to prepare your skin for a red light therapy session, this is the part that you need to read.

Most people have no idea how their skin looks like, so when they go into the doctor’s office and they've asked if they’ve had a photodynamic therapy or a laser treatment, they’re not aware of what treatment they might have received.

  • The skin absorbs red light from the sun, and in return, it produces negative ions.
  • These are similar to the particles produced by an activated oxygen generator (you know those things at the gym).
  • During photodynamic therapy, the skin cells absorb the energy from the lasers' red light, which causes the release of more negative ions, which then penetrate deeper into the skin.
  • They’re working like the “batteries” on your car — they give the batteries extra power and allow the car to run much longer.
  • If you want to learn how to prepare your skin for a red light therapy session, you must remove all the grime from your face and neck before the session.
  • Cleansing is one of the most important steps to remember in preparation.
How to Prepare Your Skin for Red Light Therapy Session by Using Non-Dry Cleanser

You might need more than just a good cleanser when trying to prepare your skin for red light therapy. Your cleanser is your friend when you are trying to remove all the dirt and excess oil from your face, but what if your cleanser is too harsh on your skin? If you have dry skin, using a cleanser containing too harsh ingredients may cause dryness, making it harder for you to remove those excess oils from your face.

When you prepare your skin for red light therapy session using the non-drying cleanser, make sure that you would be using a toner with antioxidants and anti-inflammatory ingredients to increase the collagen level the skin.

This will help keep your skin healthy and younger-looking.

Caution: Lotion and Moisturizers For LED Masks Are Not Recommended

The use of moisturizers and lotions is not recommended for LED masks because it will damage your skin. There are also cases wherein people who used such products ended up suffering from adverse effects.

The ingredients in these products may be too strong for the skin to be able to absorb.

You can prevent this by using only non-comedogenic lotions and moisturizers for LED masks.

  • This way, the product is less likely to irritate your skin. In addition to that, you can also use other types of products designed for sensitive or dry skins to use on your face during the event's preparation.
  • However, there are cases wherein people who have been using such moisturizers and lotions as part of their LED facial make-up mask ended up suffering from adverse effects.
  • In these cases, the products were not properly applied to the skin, and the amount that was applied was also insufficient.
  • Because the skin did not get sufficient moisture, the cells underneath the skin's surface could not repair themselves properly.
  • This will result in damaged skin, which will cause more breakouts than before.

Aside from lotion and moisturizers, it would help if you also stayed away from mineral oil, alcohol, and preservatives. These ingredients are not good for your skin, as they can cause dryness and irritation. It would help if you also stayed away from using creams and lotions with fragrance, which can only irritate your skin even more. Instead, look for serums.

If you want to have a glowing complexion without enduring any adverse effects, use a good quality face serum.

Prepare Your Skin For Red Light Therapy by Removing Sunscreen

You probably have heard that it is unsafe to use the sun’s UV rays at home, especially if you use a tanning lotion or a self-tanning lotion. But did you know that it is also not safe to use self-tanning products like tan accelerators and sunless tanning pills to prepare your skin for red light therapy sessions?

This defeats the purpose of using red light therapy, and you must remove sunscreen so that your face and skin are completely ready to receive the red light therapy. This is because self-tanning products contain ingredients that can affect the skin in adverse ways and block the beneficial deep penetrating infrared wavelength from 650nm to 850nm.

How to Prepare Your Skin For Red Light Therapy by Removing Makeup

If you have chosen to have laser acne treatment and you are wondering how to prepare your skin for the red light therapy, you will want to take a moment to learn how red light therapy works before getting started.

Before your session begins, you will be given a short amount of time to get ready for the procedure. This is because your skin needs to be very clean and free of any makeup. Your skin needs to be completely dry before the procedure can begin.

If there is any moisturizer on your skin when you arrive for your appointment, you will have to remove it before your treatment.

Your doctor will ask you several questions about your skin during your appointment, including what type of skin you have and whether or not you have any allergies. During this time, they will also determine if you are a good candidate for the procedure. If you are cleared for the procedure, your skin will be exposed to an intense red light level. This is one of the most effective ways to get rid of acne, and it can also help prevent scars and aging from occurring on your face.

The amount of time that it takes to get your skin prepared for red light therapy varies. In most cases, it is normal to have it take from fifteen to thirty minutes to prepare your skin for the procedure. You may have to remove any makeup at this time as well.

How to Prepare Your Skin For Red Light Therapy by Exfoliating?

When a patient is getting a therapy session done, they will be required to go to the spa or beauty clinic to be given a facial.

A therapist will then start by cleaning the face thoroughly. After the initial cleaning process, the therapist will apply a chemical that will help exfoliate the skin.

This process can irritate the skin, so it is important to prepare your skin before undergoing this procedure. Some common preparations that people use include salicylic acid, alpha hydroxy acid, retinoids, glycolic acid, and other peel-type products.

The exfoliating procedure aims to help the skin cells shed off dead skin cells and replace them with new cells.

This is why it is important to remove all traces of dead skin cells from your face before undergoing the procedure.

It may seem odd at first, but if you want to get the best results from the procedure, you need to gently exfoliate your skin.

Prepare Your Skin For Red Light Therapy With Moisturizers

When you prepare your skin for red light therapy, you are basically preparing to expose the blue spectrum laser's high intensity and the eventual dry out of the epidermis. The skin must be prepared using a good cream containing Reductase or Salicylic Acid, or by exfoliating the skin using a scrub.

After the procedure, you will need to have topical products applied to your skin to prevent the skin from cracking and peeling. This will also help improve your appearance and prevent future scarring. Removing moisturizers before the therapy can be helpful. This is because the skin’s cells will still be in a dormant state when you receive the treatment; therefore, your skin is not at risk for the dryness associated with moisturizers.

This will also improve your skin's look, especially for those who have undergone this procedure many times. However, you must be youthful if e to remove moisturizers in preparation for the session, as some creams may cause excessive dryness and irritation. Once you are prepared for the session, you can expect the doctor to start the red light therapy by generating a small amount of blue light on your skin's top layer.

The light then travels through the skin, reaching the deepest layers where most of the damage occurs. When the blue light is emitted, it is believed that the cells below the surface of the skin begin to absorb the red light, helping to repair the skin. The increased circulation and nutrient absorption help to rejuvenate your skin, leaving it looking younger and healthier than ever before.


Celebs are Loving Red Light Therapy

When it comes to anti-aging remedies, celebrities are at the forefront of all the latest treatments. For years, Hollywood’s elite have opted for chemically-induced anti-aging treatments, like botox and chemical facial peels. But it looks like Hollywood is stepping away from harsh treatments, particularly with the prominence of clean and holistic beauty trends in recent years. Now, many celebrities have decided to avoid the needles and knives, opting for natural alternatives, instead. 

To prepare for red carpet events, celebrities are flocking to red light therapy for natural, non-invasive anti-aging treatments. Kourtney Kardashian, true to Kardashian form, was relatively early to the red light therapy scene in 2016, when she posted a photo of herself in wearing a red-light mask, touting the many anti-aging benefits of the treatment. Since then, other celebrities such as Kelly Rowland, Emma Stone, and Chrissy Teigen have openly shared their positive experiences using red and blue light facial therapy treatment. 

Some actresses love red light therapy so much, they have their own equipment set-up in their homes. Back in 2018, Olivia Munn told US, "I have my own facial set up, I've got the professional-grade products and machines...But one of the best things is the red and blue light mask."

Red light therapy works by increasing blood flow and oxygen, feeding the cells the necessary energy they need to speed up the cellular process. This process helps decrease inflammation and enhance collagen production, which reduces the appearance of fine lines and wrinkles for tighter and supple skin. 

Jewelry designer and reality T.V. star Kristin Cavallari told US that she keeps away from Botox, but shared that

"I use red light therapy twice a week to prevent lines and wrinkles."

But red light therapy isn’t only for wrinkles and fine lines. Celebrities are expanding the use of red light therapy and using it for their entire bodies. Why? Well, house-friendly red light devices help treat inflammation, joint pain, and muscle soreness. 

Ara Suppiah, M.D., an assistant professor at the University of Central Florida Medical School and an emergency and sports medicine physician, told Us Weekly that “increased energy within a muscle cell allows it to contract harder and repair itself after training.” Since red light increases cell energy, it subsequently helps organs, joints, and muscles to repair themselves and function optimally. 

The list of celebrities who swear by red light therapy continues to grow by the day. Joan Smalls and Bella Hadid visit celeb aesthetician Joanna Czech, who is well-known for using her light treatments on her clients. Riverdale’s Lili Reinhart and Camila Mendes also posted photos from Joanna Vargas’ red light bed.

So, it’s clear that the verdict is in: celebrities are loving red light therapy and the multiple external and internal benefits that come along with it. But do you need to undergo expensive treatments to get a taste of the benefits? Nope! You don’t need to be a celebrity status to enjoy the benefits of red light therapy - even in the comfort of your home. 

Luckily, red light therapy is now available for in-home treatment with Lunas’ FDA and MDA-approved red light therapy devices. By having a red light therapy device in your home, we can all attain our own red-carpet glow without the celebrity price tag.

Photo Credit: By Tinseltown - Shutterstock

How to Integrate Light Therapy into your Lifestyle

Our lives are busier than ever, and even though red light therapy sounds like something that could significantly benefit you, we know you might be thinking: “when will I have time for red light therapy?” 

Part of the beauty of red light therapy is that you don't need to change your current routine or lifestyle to enjoy its benefits: if you're someone whose day is busy in front of a desk, you can turn the device on while you work; or if you have easy-going mornings but hectic afternoons, you can enjoy your morning coffee while using our red light therapy device. Or, you can turn on the panel while you’re unwinding with a movie in the evenings –– the options are endless.  

Red light therapy treatment isn’t supposed to take over your day and cause an inconvenience. With an at-home red light therapy device, you make the rules. 

That said, you may be wondering what’s the best time of day to use our red light therapy devices. Well, there are a couple of ways you can integrate red light therapy into your lifestyle. 

There are three main parts of the day: morning, midday, and evening. Though you’re able to use red light therapy any time of the day, some parts of the day can be more effective than others, particularly given your personal health and wellness needs. 

If you’re someone who’s suffering from a sleep disorder, then you may want to focus on using red light therapy during the mornings and evenings. For sleep conditions, using red light therapy around sunrise or sunset are the best times of the day. Why is that? 

It has to do with our biological circadian rhythm, which is the natural internal process that helps regulate your sleep cycle within a 24-hour day. To optimize your circadian rhythm and improve your sleep cycle, you need to sync with your natural sleep rhythm. By doing so, you reduce sleep inertia, insomnia, and other sleep disorders. 

When regulating your circadian cycle, your body releases a hormone called melatonin. This particular hormone is the highest in the blood at night and optimal for helping you fall asleep. When using red light therapy at night, it can help you enhance your natural melatonin production

When using red light therapy in the morning, exposure to light helps stop melatonin production, giving your body a natural energy boost. So, either time of the day––morning or night––can be an incredible time to help your body reset its circadian rhythm. 

You don’t need to schedule off your morning for red light therapy treatment. While you’re eating your breakfast or going through your emails, you simply turn on your red light therapy device and enjoy 10 to 15 minutes of treatment. 

Or, in the evenings when you’re cozied up on the course, washing the dishes, or sitting in bed with a book, turn on your red light therapy panel to help regulate your sleep cycle, mood, and overall health. 

If you can’t manage to use red light therapy in the morning or evening, you can always have a treatment in the afternoon, as well. If you’re dealing with a sleep disorder or seasonal depression, we recommend morning or evening treatment. However, midday treatment will also provide you with a load of benefits, including collagen production, decreasing symptoms of depression, improving sleep disorders, and non-seasonal Bipolar depressive episodes. 

Whatever the condition may be, whether it's a sleeping disorder, skin condition, or depression, Lunas red light therapy devices promote cellular healing from the inside out. What’s important is you find the time of the day that best suits your body’s needs. Everyone is different, so it’s important to find out what works for you and your unique routine and lifestyle.

Red and Blue LED Light on Milk Yield in Dairy Cows

Ruminant nutritionists formulate rations balanced according to the nutritional needs for the ruminant at a specific production level. The assumption being that the cows will eat everything they offered. However, cattle can select their feed, as they put together feed using their tongue and lips. Sorting has been studied most in cows al mixed ration (TMR) since it is often is oftenibitum, allowing cows to pick the feed particles they prefer and still reach the total dry matter (DM) they want. The TMR reports show that the most likely sorting is in favor of the short particles (mostly concentrate) and against the long particles (forages). Therefore, the feeding behavior of the cow modulates the amount of feed she eats, the nutrients she gets, rumen health, and ultimately her milk production.

Several methods have been used to try and reduce feed sorting in dairy cows. Recently, a long day photoperiod has been reported that could lower feed sorting against long particles. Today, Kaiyan provides advanced LED light equipment that is available for commercial use. The LED wavelength can be adjusted to the desired output.

Blue and red wavelength light has attracted interest in dairy barns. The cow eye is not sensitive to a red light, and therefore red light has been suggested as an option for illumination when people need to work with the animals during a time of the day when the cows have night. In humans, blue light is known to cause a carryover effect with increased activity after the light is turned off. If cows respond similarly to blue light, it may be interesting to include blue light in the dairy barns in the late afternoon or evening to stimulate activity during the night. This is of particular interest for automatic milking systems since they require cow activity around the clock. Solutions for dairy barns that include periods of the day with more red or blue LED light are already available on the market, as we now have fixtures of white LED light.

Eating Behavior of Dairy Cows

Encouraging DMI to promote milk production is one of the primary objectives for dairy farmers. The daily eating time, selection, number of meals per day, duration, and number of eating occasions per day are important aspects of feeding behavior.

Factors that Influence Eating Behavior

The environment, age of cattle, teeth condition, feed composition, and processing influence eating behavior. Just like grazing cattle, group-housed cows synchronize their behavior, including eating when kept indoors. The eating behavior of cows is controlled by social interactions, management practices, the environment, and health. Long ago, dairy cows were thought to be crepuscular eaters, motivated by sunrise and sunset timing to go for grazing. However, studies reported that fresh feed delivery timing had more influence on the feeding behavior of dairy cows kept indoors than the time of day. Also, studies found that daily eating time distribution changed following an increase in feed delivery frequency in group-housed dairy cows. The first hour and a half after fresh feed delivery is the period of peak eating activity. Little effect on cow behavior was observed when feed push-ups were done while still some feed in the trough. The feed trough design also affects feeding behavior as cows prefer eating from a feed trough that allows their head to be in a natural grazing position than having their head in an elevated position.

Types of Lights Used in Dairy and the Newly Available Light Sources

Common light sources used in dairy facilities are fluorescent and metal halide lights. During the last few years, LED lights have also become available for animal housing. This is not a new technology; LED light has been used in plant growth research since the mid-1980s but has been costly; hence limited to research only. However, 19 the Haitz’ Law as projected by Steigerwald et al., has come to action, that every decade their cost will decrease by 10 whereas their performance advances by a factor of 20. Now they have become affordable and advanced white LED lights thereby increasing their potential use in animal houses commercially

Advantages of LED Lights

It is possible to adjust the light intensity and spectral composition of LED lights mimicking that of natural day sunrise and sunset, making it possible to control color combinations, e.g., green, blue, and red. A LED light's lifespan is longer than that of fluorescent lights, around 100 000h compared to 8000 h. Furthermore, LEDs thermal output is low, saving energy, containing no mercury, efficient photoelectric conversion, and easy-to-contact to digital control systems making photoperiod management easy, for example, in dairy barns. Due to their long life span, they can decrease production costs as they do not need regular replacement and cuts off labor costs and the often-high risk work task of replacing lights since most barns have very high ceilings. The white LEDs produce light in the wavelength that cows can detect better, with peaks of emission around 460nm and 550.

In one study, ten multiparous pregnant Swedish Red cows in post-peak lactation were used. Cows were housed in a tie-stall barn. They were subjected to a 33-day red or blue LED light treatment during a long day photoperiod with 16 hours day and 8 hours night. Cows were fed silage and concentrate separately. Silage was fed three times a day, ensuring ad libitum intake with 5–10% orts. The concentrate was fed four times per day. Samples of silage were collected thrice a day, and individual orts were collected at the end of the day and the night. Data for eating behavior and milk yield were collected five days before and five days after the treatment period. Eating behavior was determined using the difference in the distribution of fractions of different straw lengths in the silage fed and orts during daytime and night time. A 2-screen Penn State Particle Separator (PSPS) (19mm and 8mm) with a solid bottom pan was used to determine the distribution of large, medium, and short silage fractions. Treatments did not affect total DMI. Overall, cows sorted for the large fractions against the medium and short fractions. During the LED period, there was a difference (P<0.001) in sorting between Red and Blue cows during the daytime. Cows on the Red LED light are sorted for the short fractions during the daytime. Blue cows showed different sorting (P<0.05) during day and night. Their sorting for the large fractions was more pronounced during daytime than night. Milk yield did not change during the trial and did not differ between the Red and Blue groups. In conclusion, sorting activity was greater during the daytime in the LED period, which could have been influenced by the LED light. Interestingly cows seem to have better vision in red than blue LED light. Furthermore, it also possible that the LED light maintains milk yield since no change was observed during the four-week trial in post-peak lactation.

Melasma & Light Therapy

Light can be a powerful skincare tool, whether it’s an LED facial or light therapy for all skin. Light therapy can also seem a little mysterious if you’ve never done it before because light doesn’t interact with the skin in the same obvious way as, say, serum or moisturizer.

Here, we’re breaking down light therapy and melasma, explaining what they are, how they work, and experts’ advice for adding them to your skincare routine.

Melasma is sometimes referred to as the mask of pregnancy because it is sometimes triggered by an increase in pregnant women's hormones. But while the condition may be common among pregnant women, it isn’t limited to them.

“It’s not only associated with pregnancy but can affect women at all stages of life,”

Says Dr. Shadi Kourosh, director of the Pigmentary Disorder and Multi-Ethnic Skin Clinic at Harvard-affiliated Massachusetts General Hospital. And it may last for many years.

“Women who develop melasma in their teens or 20s or 30s may see it stay around for decades,”

Says Dr. Barbara Gilchrest, senior lecturer on dermatology at Harvard Medical School.

What is Melasma

Melasma is a common skin problem. The condition causes dark, discolored patches on your skin.

It’s also called chloasma, or the “mask of pregnancy,” when it occurs in pregnant women. The condition is much more common in women than men, though men can get it too. According to the American Academy of Dermatology, 90 percent of people who develop melasma are women.

Causes of Melasma

It isn’t obvious what causes melasma. Darker-skinned individuals are more at risk than those with fair skin. Estrogen and progesterone sensitivity are also associated with the condition. This means birth control pills, pregnancy, and hormone therapy can all trigger melasma. Stress and thyroid disease are also thought to be causes of melasma.

Additionally, sun exposure can cause melasma because ultraviolet rays affect the cells that control pigment (melanocytes).

How is Melasma Diagnosed?

A visual exam of the affected area is often enough to diagnose melasma. To rule out specific causes, your healthcare professional might also perform some tests.

One testing technique is a Wood’s lamp examination. This is a special kind of light that’s held up to your skin. It allows your healthcare professional to check for bacterial and fungal infections and determine how many skin layers the melasma affects. To check for any serious skin conditions, they might also perform a biopsy. This involves removing a small piece of the affected skin for testing.

Light Therapy Based Treatments

Light therapy for melasma treatment is best suited for patients with refractory melasma who failed with topical treatment or a series of chemical peels. Topical therapy takes at least three months or longer to see skin lightening, and those patients who are interested in a more rapid response could consider light therapy.

When a patient wishes for an accelerated pace of improvement, analogous to chemical peels, these modalities accelerate melanin pathways’ removal. Still, they do not target the melanin production itself.

One key point of patient counseling before laser- and light-based treatment is that these therapies can speed up removing melasma-related hyperpigmentation, but they are not cures for melasma.

References

Arora P, Sarkar R, Garg VK, Arya L. Lasers to treat melasma and post-inflammatory hyperpigmentation. J Cutan Aesthet Surg.

Barolet D. Light-emitting diodes (LEDs) in dermatology. Semin Cutan Med Surg. 2008;27(4):227–238.

Lee HM, Haw S, Kim JK, et al. Split-face study using a 1,927-nm thulium fiber fractional laser to treat photoaging and melasma in Asian skin. Dermatol Surg. 2013;39(6):879–888.

Kauvar AN. The evolution of melasma therapy: targeting melanosomes using low-fluence Q-switched neodymium-doped yttrium aluminum garnet lasers. Semin Cutan Med Surg.

Weiss RA, McDaniel DH, Geronemus RG, Weiss MA. A clinical trial of a novel non-thermal LED array for reversal of photoaging: clinical, histologic, and surface profilometric results. Lasers Surg Med. 2005;36(2):85–91.

Laser Acupuncture Treatment?

Acupuncture under traditional Chinese medicine is an alternative medicine that treats patients by needle insertion and manipulation at acupoints (APS) in the body. Acupuncture causes collagen fiber contraction, resulting in soluble actin polymerization and actin stress fiber formation, affecting the nervous and immune systems. Besides, acupuncture leads to molecular changes at APs in tissues at the cellular level. The local physicochemical reactions at the APs send signals to the organs via the tissue fluid and blood circulatory systems for optimal adjustment of the body’s organs.

It is believed to have been practiced for more than 2500 years, and this modality is among the oldest healing practices in the world. Acupuncture is based on the idea that living beings have Qi, defined as inner energy, and that it is an imbalance in Qi or interruption in the flow of Qi that causes illness and disease. Acupuncture therapy is focused on rebalancing the flow of Qi, and the practice is progressively gaining credibility as a primary or adjuvant therapy by Western medical providers.

Laser Acupuncture

Kaiyan Medical has been working to create ergonomic laser pens to simulate the acupuncture process. Laser acupuncture (LA) — non-thermal, low-intensity laser irradiation to stimulate acupuncture points — has become more common among acupuncture practitioners in recent years. LA is a safer, pain-free alternative to traditional acupuncture, with minimal adverse effects and greater versatility. LA has many features that make it an attractive option as a treatment modality, including minimal sensation, short duration of treatment, and minimal risks of infection, trauma, and bleeding complications.

What is the Difference

In acupuncture, needles are inserted at specific acupoints, which may be manually stimulated in various ways, including gentle twisting or up-and-down movements. Besides, the depth of needle penetration is also manipulated by the acupuncture practitioner. The patient may report sensations of De Qi, which are feelings of pressure, warmth, or tingling in the superficial layers of the skin. Many theories to explain how acupuncture works have been proposed, including the gate-control theory of pain and the endorphin-and-neurotransmitter. Others have postulated that acupuncture modulates the transmission of pain signals and alters the release of endogenous endorphins and neurotransmitters, resulting in physiologic changes.

One clear difference between needle acupuncture and LA is that LA does not physically penetrate the skin. Despite a greater understanding of LA, it is unclear how non-thermal, low-intensity laser irradiation stimulates acupoints. The mechanism of LA may be entirely separate from our present understanding of acupuncture. Current theories postulate that LLLT could positively affect modulating inflammation, pain, and tissue repair, given appropriate irradiation parameters.

Anti-Inflammatory Effect of Lasers

Inflammation reduction comparable to that of non-steroidal anti-inflammatory drugs has been reported with animal studies that used red and near-infrared LLLT, with laser outputs ranging from 2.5 to 100 mW and delivered energy doses ranging from 0.6 to 9.6 Joules. Human studies have shown similar anti-inflammatory effects with LLLT, which may account for many associated positive clinical results.

Cellular Effects of LLLT

LLLT improves cell physiology by increasing the overall cell redox potential toward greater oxidation and increased reactive oxygen species while simultaneously decreasing reactive nitrogen species. These redox state changes activate numerous intracellular-signaling pathways, including nucleic acid synthesis, protein synthesis, enzyme activation, and cell cycle progression.17 LLLT also alters the expression of genes that can enhance cell growth and inhibit cell apoptosis.16 These cellular effects of LLLT might reflect its ability to induce long-term changes in cells and LLLT’s benefits for wound healing, nerve regeneration, and inflammation reduction.

LLLT Characteristics

Red and infrared laser wavelengths are absorbed by cytochrome C oxidase protein in the mitochondrial cell membranes. This absorption is associated with increased adenosine triphosphate production by the mitochondria, which. In turn, it increases intracellular calcium (Ca2+) and cyclic adenosine monophosphate, which serve as secondary messengers that aid in regulating multiple body processes, including signal transfer in nerves and gene expression.

The power density of a laser, defined as laser energy supplied per area (W/cm2), influences its energy penetration depth. A 50-mW laser with a beam size of 1 cm2 has an energy density of 0.05 W/cm2. In contrast, the same power laser with a beam size of 1 mm2 has an energy density of 5 W/cm2 — a higher energy density results in deeper energy penetration through the skin.

Energy transmission through the skin is also affected by the absorption of light energy by skin structures. Light wavelengths from 650 to 900 nm have the best penetration through the skin. Lower wavelengths are absorbed by melanin and hemoglobin, and wavelengths longer than 900 nm are absorbed by water. With a well-focused laser beam, red wavelengths (~ 648 nm) can penetrate 2–4 cm beneath the skin surface, and infrared wavelengths (~ 810 nm) can penetrate up to 6 cm.

Now Kaiyan has made LLLT easier to use. Kaiyan medical devices can treat multiple acupoints simultaneously at the same time.


Bear, Wolf, Lion or Dolphin: How Understanding your Sleep Type Will Change your Life

Sleep is big business these days — one in three people are believed to experience sleep deprivation — and everyone is keen to rely on the latest fashionable theory.

For years, sleep cycles were divided into two categories. People who enjoy mornings were known as “early birds.” And those of us who prefer staying up late were labeled “night owls.”

Well, step-aside birds. Mammals are the new name of the game. That’s right; scientists now believe there are four ways to classify sleep/wake cycles. In the science world, these classifications are known as chronotypes.

Chronotypes describe the periods when your body wants to sleep and when it wants to be awake. And to make it easier, the chronotype categories are named after animals. Our natural sleep tendencies are now categorized as bear, wolf, lion, and dolphin.

It is crucial to understand your animal chronotype. Once you do, you can start to schedule your life around your body’s natural cycles. Kaiyan Medical suggests that this may help you sleep better and feel more productive at work.

Two Animals are not Enough

People have different circadian rhythms. That’s just a fact of life.

Science shows that:

“The human circadian system actively synchronizes to the 24-h day via environmental signals of light and darkness.”

Circadian? A 24-hour cycle. It’s your body clock. Sleep psychologists reckon they can determine our natural sleeping patterns. By understanding our own, we can have a happier, more productive life.

Now, Chronotype is a term that describes a person’s natural rhythm. And it doesn’t only relate to sleep. Chronotypes influence all primal instincts.

Author Michael Breus, Ph.D., recently suggested that there are 4 natural chronotypes. And he named these after 4 animals that follow similar sleep/wake patterns. So, say goodbye to night owls and early birds. Wolves, lions, bears, and dolphins are the new circadian rhythm mascots.


The Chronotypes

Check out the chronotypes below and let us know in the comment section which one sounds like you!

Wolves

Alright, night owls, this is your group. Just like these nocturnal creatures, you are most alert at night. Wolves tend to stay up later and struggle with waking up early.

Only about 15% of the population falls into this group. Wolves are more productive in the later afternoon and evening.

Sleep experts recommend that wolves set their alarm for 7 a.m. (snooze for 30 minutes) and go to sleep by midnight.

Lions

Lions are the new early birds. Like these wild cats, you are most alert in the morning. You have no trouble waking up and getting to work. But, lions tend to feel the afternoon slump. And by the evening, they feel drained.

About 15% of the population identifies as a lion. Sleep experts recommend that lions wake up around 5:30 a.m. and go to sleep by 10:30 p.m.

Bears

No, you don’t need to hibernate. But, like these diurnal (awake during the day, asleep at night) creatures, you follow the solar cycle. Bears generally feel awake during the day and need 8-hours of solid sleep at night.

About 50% of the population falls into this category. This group is productive in the morning and struggles with the mid-afternoon slump. Sleep experts recommend that bears wake up around 7 a.m. and go to sleep by 11 p.m.

Dolphins

Dolphins “only sleep with half of their brain at a time?” Sound familiar? Well, this is the insomniac (often self-diagnosed) group. You might be anxious and have trouble turning your brain off at night. Dolphins usually don’t get a complete night’s sleep.

About 10% of the population falls in this category. And even though they wake-up tired, dolphins are most productive by mid-morning.

Sleep experts recommend that dolphins get up around 6 a.m. and try to sleep around midnight.

Sleep Like an Animal

Who doesn’t want a better night’s sleep and a more productive day? Start scheduling your days based on your chronotypes! Once you know more about your chronotype, you can form sleep patterns that work with (not against!) your body’s natural rhythms.

So what are you waiting for? Here in Kaiyan, we are embracing our inner animals and start following our optimal sleep schedule.



Sources:

Fischer, Dorothee et al. "Chronotypes in the US – Influence of age and sex." PubMed, 21 Jun. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5479630/

Bellis, Rich. "How To Design Your Ideal Workday Based On Your Sleep Habits." Fast Company, 26 Nov. 2017, www.fastcompany.com/40491564/how-to-design-your-ideal-workday-based-on-your-sleep-habits

Levi, Anthea. "This Is the Best Time of Day to Do Everything, According to Your Chronotype." Health.com, 31 Oct. 2016, www.health.com/mind-body/how-to-get-more-energy-chronotype

Stretch Marks & Light Therapy

Why Do We Get Stretch Marks?

A stretch mark is a type of scar called striae, meaning “thin, narrow scar”. In people who develop stretch marks, the skin has stretched faster than it can grow, such as during pregnancy, growth spurts, or rapid fat or muscle gain. The abrupt stretching causes the collagen and elastin proteins responsible for the skin’s structure and elasticity to rupture. This, in turn, causes the dermis to tear.

As the dermis tears, the body’s healing mechanisms spring into action to close the wound as quickly as possible to prevent infection and further damage.

Normally, as the skin regenerates and grows, it’s an elegantly organized latticework of collagen and elastin proteins. But when the skin tears, the body doesn’t have time to build an elegant structure to fill in the gap. Time is of the essence in any wound repair, including torn skin.

The collagen clumps together hurriedly, aiming for efficient closure of the wound before infection can set in. “Scarring is the result of a system that has learned to respond extremely quickly to a wound,” says Dr. John Newman, a cosmetic surgeon and researcher at the Laser Center of Virginia in Virginia Beach.

This haphazard process results in tough and functional but unattractive tissue — what we know as a scar. “It is kind of like nailing down a crisscross of two-by-fours over a hole in a deck,” says Newman. “It seals the hole, but it doesn’t look very nice.”

Newly formed stretch marks are darker than the surrounding skin and can be slightly raised, itchy, or painful. If they’re left untreated, they become permanent scars. Their color will lighten, and their appearance will fade below the top layer of the surrounding skin.

The bigger mystery is why stretch marks don’t disappear over time as the skin regenerates. The key lies in the information that emerging cells receive from adult cells in the area. Skin cells, whether they’re normal cells or scar cells, regenerate about once every 30 days. Growth of new skin cells begins at the bottom-most layer of the scar, and older (dying) cells are pushed to the surface where they naturally slough off.

However, Neuman explains that that that that emerging cells “learn” from their immediate neighbors and predecessors and develop the same characteristics as ir replacement their replacement cells. As a result, any emerging cell in contact with scar cells will become new scar tissue rather than normal skin tissue.

Red Light Therapy For Stretch Marks

If you have tried to get rid of stretch marks, perhaps you’ve used specialized creams that contain retinoids. These work to some extent, but only if you catch your stretch marks early and treat them while they’re still forming. Retinoids work by stimulating collagen production. However, they can irritate sensitive individuals, and doctors often recommend that pregnant women avoid anything containing retinoids.

Another common treatment, known as microdermabrasion, essentially involves “sandblasting” the skin with tiny crystals. This sloughs off dead skin

cells and stimulates the production of collagen. Microdermabrasion is a fairly harsh treatment that can lead to irritation and damage, especially to sensitive skin.

The most extreme treatment for stretch marks is plastic surgery, such as a mini tummy tuck. This may be effective, but there are risks associated with any invasive procedure and the high cost.

Is there a better option for restoring the appearance of the skin? The answer is yes, absolutely. Also known as photobiomodulation and low-level light therapy (LLLT), red light therapy improves skin appearance, reduces signs of aging, treats chronic skin conditions, reduces scarring, and promotes skin wound healing.

When red light therapy is used, visible red light and invisible near-infrared (NIR) light are applied to the skin with LED bulbs' devices. Wavelengths of light are measured in nanometers (nm), with red light ranging from 630nm to 660nm and NIR light ranging from 810nm to 850nm. Human cells respond favorably to these wavelengths, similar to how natural sunlight affects plant cells by stimulating more energy and optimization of cell function.

When the red light is shone on bare skin, it soaks into the mitochondria, colloquially referred to as the powerhouses of cells' energy factories. The mitochondria are, in turn, stimulated to produce more adenosine triphosphate (ATP), which is the primary cellular fuel. This energizes cells to perform their normal functions, from fighting off pathogens to performing repair and regeneration.

Improved Blood Flow

Proper healing relies on good circulation to the skin. Red light promotes the proliferation of endothelial cells, which make up the inner layer of capillaries (the tiny blood vessels that deliver oxygen and nutrients throughout the body). This was the focus of a 2017 study by a team of researchers from Austria, who found that red light consistently increased migration and proliferation of endothelial cells.

Without proper blood circulation, there would be no healing since endothelial cells also deliver white blood cells to the sites they need. In skin wound healing, white blood cells are necessary to protect the vulnerable area from infection while the wound closes up.

Reduced Inflammation

Acute inflammation results in the redness that’s noticeable in fresh stretch marks. This is a normal and necessary part of the tissue regeneration scar's process. Acute inflammation, which is a function of the immune system, actually sets the stage for normal tissue repair and regeneration. Inflammation is quickly followed by the production of new skin structures — which, as previously described, are hastily assembled to ensure that the torn skin doesn’t become infected.

But sometimes, the inflammatory process continues after the wound has healed, leading to chronic inflammation. It can lead to a variety of widespread problems throughout the body, including disease. “Some inflammation is good,” says Dr. Robert H. Shmerling, an associate professor of medicine at Harvard Medical School. “Too much is often bad. The goal is to recognize when inflammation is simply doing its job, and when it can potentially cause problems.”

Hundreds of studies have shown how red light therapy can significantly reduce inflammation. Many of these were conducted by Dr. Michael A. Hamblin, an associate professor of dermatology at Harvard Medical School and a noted expert on red light therapy. In the final report of a 2017 study, Hamblin refers to red light therapy’s “pronounced anti-inflammatory effects.”

Mobilize Stem Cells

During the skin-rebuilding phase, stem cells, which are unspecialized “master” cells, mobilize to the site and develop into most any type of specialized cells that are needed by the body. Ideally, they develop into normal skin cells, rather than scar tissue, to replenish damaged or destroyed cells due to skin tearing.

Red light has been shown to activate stem cells. As Barbara Gefvert, editor-in-chief of BioOptics World, explains: “Recent research shows … that noninvasive application of light can boost the natural growth of an individual’s own stem cells to enable exciting new treatments.” Stem cells can assist with the tissue regeneration process and stimulate normal and healthy behavior in existing cells. This can prevent the formation of new stretch marks and gradually reduce the appearance of existing stretch marks.



Lighting the Way Back for Astronauts - Light Therapy & NASA

In 1993, Quantum Devices, Inc. (QDI), of Barneveld, Wisconsin, began developing the HEALS (High Emissivity Aluminiferous Light-emitting Substrate) technology high-intensity, solid-state LED lighting systems for NASA Space Shuttle plant growth experiments. The company evolved out of cooperative efforts with the Wisconsin Center for Space Automation and Robotics (WCSAR) at the University of Wisconsin-Madison — a NASA center for the Commercial Development of Space. Ronald W. Ignatius, QDI’s president, and chairman represented one of WCSAR’s industrial partners at the time. WCSAR was conducting research on light sources for promoting food growth within closed environments where humans would be present for a long duration, such as the Space Shuttle and the International Space Station.

With the support of WCSAR, Ignatius experimented with LEDs, which provide high-energy efficiency and virtually no heat, despite releasing waves of light 10 times brighter than the Sun. Ignatius admits that some scientists involved in the project were skeptical at first, thinking that the idea of using LEDs to promote plant growth was far-fetched. However, the experiments demonstrated that red LED wavelengths could boost the energy metabolism of cells to advance plant growth and photosynthesis. This finding prompted Ignatius to develop a line of LED products that emit the exact wavelength of light that plants use in photosynthesis.

“Our company gives credit to Dr. Ray Bula, the director of WCSAR, for having the foresight to go against the prevailing dogma of the time and design the first plant experiment using monochromatic light to grow lettuce plants,” Ignatius proclaims.

In 1989, Ignatius formed QDI to bring the salt grain-sized LEDs to market. In October 1995, the light sources made their Space Shuttle flight debut on the second U.S. Microgravity Laboratory Spacelab mission (STS-73, Columbia).

Growing

When NASA determined that red LEDs could grow plants in space, Marshall Space Flight Center awarded QDI several Small Business Innovation Research (SBIR) contracts to investigate the broad-spectrum diodes' effectiveness in medical applications. The contracts, issued from 1995 to 1998, focused on increasing energy inside human cells. NASA hoped that the LEDs would yield medical benefits on Earth and stem bone and muscle mass loss in astronauts, which occurs during long periods of weightlessness. (In space, the lack of gravity keeps human cells from growing naturally.) Furthermore, since wounds are slow to heal in a microgravity environment, LED therapy could accelerate healing and keep what would be termed as minor wounds on Earth from becoming mission-catastrophic in space.

In addition to promoting cell growth, the red LEDs are capable of activating light-sensitive, tumor-treating drugs that, when injected intravenously, could destroy cancer cells while leaving surrounding tissue virtually untouched. The technique, approved by the U.S. Food and Drug Administration (FDA) for use in laboratory and human trials, is known as Photodynamic Therapy.

With the SBIR assistance from NASA, QDI set out to alter a surgical probe that could emit long waves of red light to stimulate a Benzoporphyrin-derivative drug called Photofrin, which delivers fewer post-operative side effects than comparable drugs. Ignatius also developed a friendly and successful working relationship with Dr. Harry Whelan, pediatric neurology and director of hyperbaric medicine at the Medical College of Wisconsin in Milwaukee. The two had met after Ignatius came across a newspaper article highlighting Whelan’s ground-breaking brain cancer surgery technique, which uses drugs stimulated by laser lights to accelerate healing. Accordingly, QDI provided more than $1.25 million from its SBIR contracts to support Whelan’s pioneering photobiomodulation research and bring him on board to help improve the surgical probe.

Collectively, Ignatius, Whelan, and researchers from NASA successfully altered the probe for pediatric brain tumors and the prevention of oral mucositis (a common side effect of chemotherapy and radiation treatments) in pediatric bone marrow transplant patients at the Medical College of Wisconsin. In May 1998, a 20-year-old female became the first patient to undergo surgery with the modified probe. The young woman had endured six brain surgeries and chemotherapy and radiation treatments over a span of 10 years, but her aggressive cancer kept coming back. Having exhausted all of her conventional treatment options, she turned to the NASA-sponsored Photodynamic Therapy technology.

During the procedure, surgeons excised as much of the recurring brain tumor as they could then injected the light-activated Photofrin into her bloodstream and inserted the LED probe into the remaining tumor tissue. The probe, which casts long wavelengths that generate less heat and penetrate deeper into tissue than the shorter wavelengths of traditional medical lasers, proved to be both safe and effective, as the tumor never returned, and the patient recovered with no complications. A second operation that took place 3 months later on a male patient was also deemed successful by Whelan and his Medical College of Wisconsin surgeons' team.

FDA-approved clinical trials continued at several other facilities over the next 3 years, including the Roswell Park Cancer Institute in Buffalo, New York; Rush-Presbyterian-St. Luke’s Medical Center in Chicago; and the Instituto de Oncologia Pediatrica in Sao Paulo, Brazil. QDI became recognized as a U.S. Space Foundation “Space Technology Hall of Fame” award recipient in 2000 and a Marshall Space Flight Center “Hallmark of Success” in 2004.

Product Outcome

The positive clinical trial results and continued support from NASA and follow-on research grants from the Defense Advanced Research Projects Agency helped QDI and the Medical College of Wisconsin fully transition space technology into a new, non-invasive medical device. The WARP 10 (Warfighter Accelerated Recovery by Photobiomodulation) is a high-intensity, hand-held, portable LED unit intended for the temporary relief of minor muscle and joint pain, arthritis, stiffness, and muscle spasms. It also promotes the relaxation of muscle tissue and increases local blood circulation. Unlike the surgical probe, the WARP 10 does not require intravenous medicine; instead, the unit can be placed directly on the skin where treatment is to occur.

The WARP 10 was designed to aid armed forces personnel on the front lines with immediate first aid care for minor injuries and pain, thereby improving combat endurance. The “soldier self-care” device produces 80 times more photon energy than a 250-Watt heat lamp, yet it remains cool to the touch. The power advantage reduces the time required for each therapeutic dose and provides for faster multi-dose exposures when needed, without the harmful effects of ultraviolet solar radiation. The U.S. Department of Defense and the U.S. Navy are currently issuing WARP 10 to crews on submarines and Special Forces operations.

QDI has introduced an FDA-approved consumer version sharing the same power and properties of the military model as an alternative to the cost and complications associated with the overuse of non-steroidal anti-inflammatory drugs (NSAIDs) for persistent pain relief. According to a Mayo Clinic study, adverse events associated with the use of NSAIDs are reported more frequently to the FDA than such events associated with any other group of drugs. Furthermore, conservative calculations for the United States estimate that approximately 107,000 patients are hospitalized each year for NSAID-related gastrointestinal complications. At least 16,500 NSAID-related deaths occur annually among arthritis patients alone, according to compiled research.

References

Beauvoit B., Evans S.M., Jenkins T.W., Miller E.E., Chance B., “Contribution of the Mitochondrial Compartment to the OpticalProperties of the Rat Liver: A Theoretical and Practical Approach,” Analytical Biochemistry 226, 167-174 (1995).Beauvoit B., Kitai T., Chance B., “Correlation between the Light Scattering and the Mitochondrial Content of Normal Tissues andTransplantable Rodent Tumors,” Biophysical Journal 67, 2501-25 10 (1994).Chance B., Nioka S., Kent J., McCully K., Fountain M., Greenfield R., Holtom G., “Time-Resolved Spectroscopy of Hemoglobin andMyoglobin in Resting and Ischemic Muscle,” Analytical Biochemistry 174, 698-707 (1988)Conlan M.J., Rapley J.W., Cobb C.M., “Biostimulation of wound healing by low-energy laser irradiation,” J.Clin. Periodont. 23, 492-496 (1996).Eggert H.R., Blazek V., “Optical Properties of Normal Human Brain Tissues In The Spectral Range of 400 to 2500 nm,” Advances inExperimental Medicine & Biology 333, 47-55 (1993).Karu T., “Photochemical Effects Upon the Cornea, Skin and Other Tissues (Photobiology Of Low-Power Laser Effects,” HlthPhysics 56, 69 1-704 (1989).Lubart R., Friedman H., Sinyakov M., Cohen N., Breitbart H., “Changes in Calcium Transport in Mammalian Sperm Mitochondriaand Plasma Membranes Caused by 780 nm Irradiation,” Lasers in Surg & Med 21, 493-499 (1997).Lubart R., Wollman Y., Friedman H., Rochkind S. Laulicht L., “Effects of visible and near-infrared lasers on cell cultures,” Journalof Photochemistry & Photobiology 12(3), 305-3 10 (1992).Salansky N., “Low energy photon therapy for wound healing.” Intnl Med Instr, Canadian Defense Ministry, PersonalCommunication. (1998).Schmidt M.H., Bajic D.M., Reichert K.W. II, Martin T.S., Meyer G.A., Whelan H.T., “Light –emitting diodes as a light source forintra-operative photodynamic therapy.” Neurosurg 38(3), 552-556 (1996).Schmidt M.H., Reichert K.W. II, Ozker K., Meyer G.A., Donohoe D.L., Bajic D.M., Whelan N. T., Whelan H. T., “PreclinicalEvaluation of Benzoporphyrin Derivative Combined with a Light-Emitting Diode Array for Photodynamic Therapy ofBrain Tumors.” Pediatr Neurosurg 30, 225-231 (1999).Whelan H.T., Schmidt M.H., Segura A.D., McAuliffe T.L., Bajic D.M., Murray K.J., Moulder J.E., Strother D.R., Thomas J.P., MeyerG.A., “The role of photodynamic therapy in posterior fossa brain tumors: A pre-clinical study in a canine glioma model.”Journal of Neurosurgery 79(4), 562-8 (1993).5Whelan H.T., Houle J.M., Donohoe D.L., Bajic D.M., Schmidt M.H., Reichert K.W., Weyenberg G.T., Larson D.L., Meyer G.A.,Caviness J.A., “Medical Applications of Space Light-Emitting Diode Technology—Space Station and Beyond.” SpaceTech. & App Int’l Forum 458, 3-15 (1999).Yu W., Naim J.O., Lanzafame R.J., “The Effect Of Laser Irradiation On The Release Of bFGF From 3T3 Fibroblasts.”Photochemistry & Photobiology 59, 167-70 (1994).

Light and the Moon

The moon shines because its surface reflects light from the sun. And even though it sometimes seems to shine very brightly, the moon reflects only between 3 and 12 percent of the sunlight that hits it.

The moon’s perceived brightness from Earth depends on where the moon is in its orbit around the planet. The moon travels once around Earth every 29.5 days, and during its journey, it’s lit from varying angles by the sun.

This moon’s movement around the Earth — and the simultaneous orbiting of Earth around the sun — account for the moon’s different phases (full moon, quarter moon, etc.). At any given point in the moon’s trajectory around the Earth, only half of its surface is facing the sun, and therefore, only half of the moon is lit up. The other half of the surface faces away from the sun and is in shadow.

Now, I took my first moonlight photograph in 1998, using my father’s old Kodak camera. The results were almost invisible, of course. It was pretty clear that I had no idea what I was doing. But I did know that the feeling of being out under the stars was one that I needed to capture somehow, and I had to find a way to go about doing it.

I left the moonlight photography for a while. Some years later, I read that the brightness of moonlight is extremely variable over a range of many stops and that it was nearly impossible to figure out the brightness of a given scene was going to be ahead of time. The brightness of moonlight under clear skies is as easily predictable as is the brightness of sunlight under similar conditions.

Several things cause moonlight brightness to vary. The most obvious is the moon’s phase. The brightness of moonlight varies by approximately a factor of 10 between the quarter phase and full moon, based on a diffuse reflection and the geometry of the positions of the earth, sun, and moon alone. This is about three and a half stops of light, which is substantial. Another factor is the distance between the earth, moon, and sun, which changes due to the earth and lunar orbits not being perfect circles. The distance from the earth to the sun varies from 0.9833 Astronomical Units at perihelion to 1.0167 Astronomical Units at aphelion. The earth’s distance to the moon varies from 356,400 kilometers at extreme perigee to 407000 kilometers at extreme apogee. The amount of light that falls on a body varies with the inverse square of the distance from the light source, so the combined effect of these distance variations can be quite pronounced. The range of lunar illumination variation is 6.9% for variation in sun distance and 30% for moon distance variation. This amounts to about one-third stop of brightness, which enough to change the mood of a photo when slide films are used.

The third factor in moonlight brightness is the so-called opposition effect. The surface of the moon is covered with small glassy particles that can serve as wonderful retro-reflectors. If you are within a small angle to the line between the sun and moon, the amount of light coming from the moon increases dramatically relative to what you would expect from a diffuse reflection alone. There is quite a range in the magnitude of this effect presented in scientific literature, ranging from a factor of 1.35 to 20! Whatever value you choose to use, the effect is at least one-third stop of light, making it significant to use slide film.

The final parameter that introduces variation into moonlight brightness is atmospheric attenuation, or atmospheric extinction, to use astronomer’s jargon. This accounts for the amount of light absorbed or scattered when light from the moon passes through the earth’s atmosphere. There are two factors involved: the amount of reduction per a given amount of air transited by the light (the “extinction coefficient”) and the amount of air in the light path (“air mass”). Three principal phenomena contribute to the extinction coefficient: molecular absorption, molecular (Rayleigh) scattering, and aerosols’ scattering (particles larger than molecules). See my web page on atmospheric attenuation for more on these individual factors. Overall, an extinction coefficient value is small for dry, clear air but can be huge for moist, dusty air. And the amount of air the light passes through can vary from one “air mass” with the moon directly above you to forty “air masses” when the moon is on the horizon.

So how bright can moonlight be? The brightest moonlight occurs with the moon at perigee and the earth at perihelion, right at the full moon phase. You can never have the moon at its theoretically fullest phase, right opposite the earth from the sun, because whenever the moon goes there, it enters the earth’s shadow, and we get a lunar eclipse! But assuming the eclipse didn’t happen, we could assume the following: a phase angle of zero, apparent air with an “extinction coefficient” of 0.11 magnitudes per air mass, the moon on the zenith so that the moonlight passes through a single “air mass,” the brightness would be 0.0462-foot-candles (LV -2.0), neglecting “the opposition effect.” If we include “the opposition effect,” the brightness could be anywhere from 35% to 20 times brighter (note that 35% is the more accepted value in the scientific literature, which would give an LV of -1.7). I once measured moonlight brightness with a Gossen Luna-Pro incident light meter in mid-winter on the Kelso Dunes at LV=-2.2, so this is a believable result.

There is a rule of thumb, sometimes called the Looney 11 Rule, which says we should treat the moon as being 250,000 times dimmer than the sun. This would have us use a shutter speed 18 stops slower than the 1/(film speed) value that is used in the “Sunny 16 Rule”, which works out to about 44 minutes at f/16 under moonlight conditions with the film having an ISO speed rating of 100 (uncorrected for reciprocity failure!). This is close enough to be useful under full moonlight conditions given an average earth-moon and earth-sun distance, with the moon high in the sky and clear air. Actually, since the sun has an astronomical visual magnitude of -26.74 and the full moon an astronomical visual magnitude of -12.73, the sun is more like 402,000 times brighter than the moon 18.6 stops. Thus using this rule pretty much ensures a minimum of 2/3 stop underexposure — which may actually be fine, since most of the time you want an underexposure to give the impression of the night in the image.

Surprisingly, the moonlight is actually a slightly warmer color than sunlight, as the moon reflectance is higher for longer wavelengths. Yet, on clear nights, with the full moon high in the sky (as little atmospheric influence as possible), the landscape around us appears blueish because of the Purkinje effect: at low illumination levels, our red color sensitivity decreases (as our vision system gradually switches from daylight (cones) to night time vision (using rod cells)).

That’s why the sunlight looks “warm” (more yellow), and the moonlight looks “cold” (bluer — because the insufficient light level changes our color perception), even though the real colors are pretty much the same.

In fact, this is can even become a real problem when taking very long exposure photos at night! They look almost like daylight photos, destroying the intended atmosphere of mystery. Objectively, the photograph is correct, but it is not what we see with our own eyes. Add some blue tint and the night feeling is back.

References

Parkinson's: From the Gut to the Brain

Margaret Jarrett was diagnosed with Parkinson’s disease eight years ago. And although she was bothered by many of the symptoms that commonly afflict people living with Parkinson’s — resting tremor, uncertain gait, and terrible nightmares — the thing that bothered her the most was the loss of her sense of smell. An avid gardener, she took great pride in her roses but being unable to inhale their perfumed scent really got her down.

“You take something like your sense of smell for granted,” Jarrett, 72, said. “You don’t realize how precious something is until it’s gone.”

Parkinson’s disease combines movement disorders, including resting tremors, muscle rigidity, impaired balance, and movement slowness. It can also cause neurological problems such as depression, insomnia, memory loss, and confusion.

Its cause is unknown, but it is associated with dopamine depletion and destruction of neurons in the brain's basal ganglia region.

The current mainstay of treatment for Parkinson’s disease involves physical therapy and medications that act to increase dopamine levels in the brain. One relatively new therapy for Parkinson’s is exposure to infrared light.

Dr. Ann Liebert, co-ordinator of photomolecular research at the Australasian Research Institute, has been exploring the idea of using infrared light to modulate the gastrointestinal tract’s microbiome in humans.

The gut’s microbiome — composing trillions of bacteria, fungi, and protozoa from hundreds of different species that normally inhabit our gastrointestinal tract — has come under increasing scientific attention over the past decade, with links being established between the microbiome and several conditions including obesity, type 2 diabetes, cardiovascular disease, and depression. Several studies have also observed that the gut microbiome is markedly altered in patients with Parkinson’s disease. Fecal microbiota transplantation can have a protective effect in animal models of Parkinson’s.

The reason for this is unknown. However, an interesting observation is that another common pathology seen in Parkinson’s disease is the accumulation of misfolded proteins, called Lewy bodies, in the brain. It has been shown that certain sensory cells of the gut contain these same proteins.

Researchers have hypothesized that abnormal forms of the protein could travel from the gut to the brain through the vagus nerve, a phenomenon observed in animal models of Parkinson’s. Further support for this theory comes from findings that people who have had a surgical vagotomy — where branches of the nerve are cut — have a lower lifetime risk of developing Parkinson’s.

“We know that infrared light can reduce Parkinson’s symptoms and offer protection to brain cells. So, we wanted to test if it could modulate the gut’s microbiome as well,” Liebert said.

Provisional results from the first half dozen Adelaide participants, including Margaret Jarrett, have been promising.

“The six patients . . . showed an increase by up to 20 percent in the favorable microbiome that is associated with obesity reduction and short-chain fatty acid production. And the bacteria associated with rheumatoid arthritis, Crohn’s disease and insulin resistance were all decreased,” said Hosen Kiat, a professor of cardiology at Macquarie University, who oversaw the trial.

“For the last three years, I haven’t been able to smell flowers,” Jarrett said. “But several weeks into the trial, I started to smell my roses, daphnes, and gardenias again, and it was wonderful.”

Another participant, Barry Weldon, 70, had a similar experience. “My sense of smell improved significantly,” he said. “One day, I walked into the house, and for the first time in a long time, I could actually smell the soup my wife was cooking.”

Ron Till, 68, had an even more dramatic improvement. “The trial gave me the ability to sleep again,” he said. “It was amazing.”

Till’s neurologist cautioned him not to get his hopes up before the trial but changed his mind when he saw the results. “He told me it was voodoo medicine and probably wouldn’t work,” Till recalled. “But after the trial, I went back for my three-monthly assessment with him, and he said to me, ‘You’re actually testing better than when you first started with me ten years ago.’”

Retired geologist Sean Kennedy, 76, also experienced an improvement in his coordination and balance. “My juggling skills have improved,” he said.

In a review published in Photobiomodulation, Photomedicine and Laser Surgery, Liebert and her co-authors acknowledge that while the exact mechanism by which light therapy alters the microbiome is unknown, there is definite potential in light therapy.

“The ability of PBM [light therapy] to influence the microbiome (if proven to apply to humans) will allow an additional therapeutic route to target multiple diseases, including cardiovascular disease and Parkinson’s disease, many of which have thus far eluded effective treatment approaches,” the paper concludes.

Kiat is excited by light therapy’s potential. “If we can create non-­invasively a metabolically healthier microbiome through this extremely cheap and easy way, then inflammatory diseases and neurodegenerative diseases should be positively influenced,” he said.

Gold Coast-based GP Mark Jeffery is a clinician who has been using lasers in his practice for more than four years. He says the research supports the use of light therapy for a wide range of diseases, including Parkinson’s, Alzheimer’s, depression, and chronic pain.

“The reality is there are no real side effects from low-level laser therapy, and it’s one of the safest treatments you can ever do,” he says.

Liebert says the promising results they have seen thus far will inform a large, double-blinded randomized control trial planned for this year. “It has the potential to apply to huge fields of medicine,” she said.

Weldon’s neurologist, Chris Kneebone, is keeping an open mind on infrared light therapy’s potential. “We all just have to wait and see what the trial results tell us,” he said.

His advice for people who wish to give it a try for their Parkinson’s? “If you want to give it a go, give it a go,” he said. “I’ve got no reason not to recommend it, but at this stage, I’ve got no reason to think it is helpful either.”

As for Jarrett, she has no doubts that infrared light therapy has helped her. She enjoys pottering around in her garden again and has more energy than she has had for a long time.

“I feel like I could take on the world again,” she said. “My garden has never looked better.”

References

https://pubmed.ncbi.nlm.nih.gov/30074108/

https://pubmed.ncbi.nlm.nih.gov/29247431/

How Intense Light can Protect Against Heart Attacks

Researchers at the University of Colorado Anschutz Medical Campus have found that intense light amplifies a specific gene that bolsters blood vessels and offers protection against heart attacks.

"We already knew that intense light can protect against heart attacks, but now we have found the mechanism behind it.”

Study’s senior author Tobias Eckle, MD, PhD, professor of anesthesiology, University of Colorado School of Medicine

The study was published recently in the journal Cell Reports.

The scientists discovered that housing mice under intense light conditions for one week robustly enhances cardioprotection, which resulted in a dramatic reduction of cardiac tissue damage after a heart attack. They also found that humans could potentially benefit from a similar light exposure strategy.

To find out why they developed a strategy to protect the heart using intense light to target and manipulate the function of the PER2 gene, which is expressed in a circadian pattern in the part of the brain that controls circadian rhythms.

By amplifying this gene through light, they found that it protected cardiovascular tissues against low oxygen conditions like myocardial ischemia, caused by reduced oxygen flow to the heart.

They also discovered that the light increased cardiac adenosine, a chemical that plays a role in blood flow regulation.

Mice that were blind, however, enjoyed no cardioprotection indicating a need for visual light perception.

Next, they investigated whether intense light had similar effects on healthy human volunteers. The subjects were exposed to 30 minutes of intense light measured in lumens. In this case, volunteers were exposed to 10,000 LUX, or lumens, on five consecutive days. Researchers also did serial blood draws.

The light therapy increased PER2 levels as it did in mice. Plasma triglycerides, a surrogate for insulin sensitivity and carbohydrate metabolism, significantly decreased. Overall, the therapy improved metabolism.

Eckle has long known that light plays a critical role in cardiovascular health and regulating biological processes. He pointed out that past studies have shown an increase in myocardial infarctions during darker winter months in all U.S. states, including sunnier places like Arizona, Hawaii, and California. The duration of the light isn’t as important as the intensity, he said.

“The most dramatic event in the history of the earth was the arrival of sunlight,” Eckle said. “Sunlight caused a great oxygen event. With sunlight, trillions of algae could now make oxygen, transforming the entire planet.”

Eckle said the study shows, on a molecular level, that intensive light therapy offers a promising strategy in treating or preventing low oxygen conditions like myocardial ischemia.

He said if the therapy is given before high-risk cardiac and non-cardiac surgery, it could offer protection against injury to the heart muscle, which can be fatal.

“Giving patients light therapy for a week before surgery could increase cardioprotection,” he said. “Drugs could also be developed that offer similar protections based on these findings. However, future studies in humans will be necessary to understand the impact of intense light therapy and its potential for cardioprotection.”

Source:

University of Colorado Anschutz Medical Campus

Journal reference:

Oyama, Y. et al. (2019) Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the Endothelium. Cell Reports. doi.org/10.1016/j.celrep.2019.07.020.


Fetuses May be Able to See More Light than you Think

By the second trimester, long before a baby's eyes can see images, they can detect light.

But the light-sensitive cells in the developing retina -- the thin sheet of brain-like tissue at the back of the eye -- were thought to be simple on-off switches, presumably there to set up the 24-hour, day-night rhythms parents hope their baby will follow. University of California, Berkeley, scientists have now found evidence that these simple cells actually talk to one another as part of an interconnected network that gives the retina more light sensitivity than once thought, and that may enhance the influence of light on behavior and brain development in unsuspected ways.

In the developing eye, perhaps 3% of ganglion cells -- the retina cells that send messages through the optic nerve into the brain -- are sensitive to light. To date, researchers have found about six different subtypes that communicate with various places in the brain. Some talk to the suprachiasmatic nucleus to tune our internal clock to the day-night cycle. Others send signals to the area that makes our pupils constrict in bright light.

But others connect to surprising areas: the perihabenula, which regulates mood, and the amygdala, which deals with emotions.

Recent evidence suggests that in mice and monkeys, these ganglion cells also talk with one another through electrical connections called gap junctions, implying much more complexity in immature rodent and primate eyes than imagined.

"Given the variety of these ganglion cells and that they project to many different parts of the brain, it makes me wonder whether they play a role in how the retina connects up to the brain," said Marla Feller, a UC Berkeley professor of molecular and cell biology and senior author of a paper that appeared this month in the journal Current Biology. "Maybe not for visual circuits, but non-vision behaviors. Not only the pupillary light reflex and circadian rhythms, but possibly explaining problems like light-induced migraines, or why light therapy works for depression."

Parallel systems in developing retina

The cells, called intrinsically photosensitive retinal ganglion cells (ipRGCs), were discovered only 10 years ago, surprising those like Feller, who studied the developing retina for nearly 20 years. She played a major role, along with her mentor, Carla Shatz of Stanford University, in showing that spontaneous electrical activity in the eye during development -- so-called retinal waves -- is critical for setting up the correct brain networks to process images later on.

Hence her interest in the ipRGCs seemed to function in parallel with spontaneous retinal waves in the developing retina.

We thought they (mouse pups and the human fetus) were blind at this point in development. We thought that the ganglion cells were there in the developing eye, that they are connected to the brain, but that they were not really connected to much of the rest of the retina, at that point. Now, it turns out they are connected to each other, which was a surprising thing."

Marla Feller, the Paul Licht Distinguished Professor in Biological Sciences and a member of UC Berkeley's Helen Wills Neuroscience Institute.

UC Berkeley graduate student Franklin Caval-Holme combined two-photon calcium imaging, whole-cell electrical recording, pharmacology, and anatomical techniques to show that the six types of ipRGCs in the newborn mouse retina link up electrically, via gap junctions, to form a retinal network that the researchers found not only detect light but respond to the intensity of the light, which can vary nearly a billionfold.

Gap junction circuits were critical for light sensitivity in some ipRGC subtypes. Still, not others, providing a potential avenue to determine which ipRGC subtypes provide the signal for specific non-visual behaviors that light evokes.

"Aversion to light, which pups develop very early, is intensity-dependent," suggesting that these neural circuits could be involved in light-aversion behavior, Caval-Holme said. "We don't know which of these ipRGC subtypes in the neonatal retina actually contributes to the behavior, so it will be fascinating to see what role all these different subtypes have."

The researchers also found evidence that the circuit tunes itself in a way that could adapt to the intensity of light, which probably has an important role in development, Feller said.

"In the past, people demonstrated that these light-sensitive cells are important for things like the development of the blood vessels in the retina and light entrainment of circadian rhythms, but those were kind of a light on/light of the response, where you need some light or no light," she said. "This seems to argue that they are actually trying to code for many different intensities of light, encoding much more information than people had previously thought."
Source:

University of California, Berkeley

Journal reference:

Caval-Holme, F., et al. (2019) Gap Junction Coupling Shapes the Encoding of Light in the Developing Retina. Current Biology. doi.org/10.1016/j.cub.2019.10.025.


Light Therapy can Benefit Patients with TBI (Traumatic Brain Injury)

According to a pioneering study by researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH), light therapy is safe and has measurable effects on the brain.

Senior investigators Rajiv Gupta, MD, Ph.D., director of the Ultra-High Resolution Volume CT Lab at MGH and Benjamin Vakoc, Ph.D., at the Wellman Center led the study, which was supported by a grant from the Department of Defense (DOD) and published in JAMA Network Open September 14th.

This study is one of the first, if not the first, prospective, randomized, interventional clinical trials of near-infrared, low-level light therapy (LLLT) in patients who recently suffered a moderate brain injury. If further trials support these findings, light therapy could become the first widely-accepted treatment for this type of injury.

TBI is the leading cause of traumatic injury worldwide, and an estimated 69 million people experience such an injury every year. However, there are no treatments for this condition yet, largely because the underlying biological mechanisms are not well understood. It is so challenging to do studies with actual patients in the acute stage of trauma.

"The Gulf War put TBI in the headlines because body armor had been greatly improved by then. But there were still brain injuries caused by the shock waves from high powered explosives.”

Rajiv Gupta, MD, PhD, Director, Ultra-High Resolution Volume CT Lab

For various reasons, the number of TBIs has increased around the globe since then, but effective treatments are still sorely needed. For this study, a special helmet had to be designed specifically to deliver the therapy, an undertaking that required a mix of medical, engineering, and physics expertise.

This multidisciplinary team included Gupta, a neuroradiologist, Vakoc, an applied physicist, and others specializing in developing and translating optical instrumentation to the clinic and biologic laboratories. Both Gupta and Vakoc are also associate professors at Harvard Medical School.

“For this study, we designed a practical, near-infrared treatment based on Wellman Center research and working directly with DOD on the vexing problem of TBI, a condition faced by so many,” says Rox Anderson, MD, the center’s director.

Another challenge was optimizing the wavelength of the near-infrared LLLT.

“Nobody knows how much light you need to get the optimal effect,”

explains Lynn Drake, MD, one of the study co-authors and director of business development at the Wellman Center.

“We tried to optimize the wavelength, dosing, timing of delivery, and length of exposure.”

This was done through a series of pre-clinical experiments led by Anderson. These included multiple preclinical studies led by Michael Hamblin, Ph.D. Anderson and Hamblin are both co-authors of this paper.

Near-infrared LLLT has already been considered for multiple uses, but to date, few if any studies of this technology have been tested and none in patients with TBI.

It has been studied in stroke patients, and Wellman's basic laboratory research suggests it is neuroprotective through a mechanism mediated by specialized intracellular organs called mitochondria. It took several years of research at Wellman to understand the basic mechanism before the clinical trial.

The randomized clinical trial included 68 patients with moderate traumatic brain injury who were divided into two groups. One group received LLLT via the special helmet, which delivered the light. Patients in the control group wore the helmet for the same amount of time but did not receive the treatment.

Vakoc’s team at Wellman designed the helmet. During the study, the subjects’ brains were tested for neuron activity using quantitative magnetic resonance imaging (MRI) metrics, and the subjects also underwent neurocognitive function assessment.

MRI was performed in the acute (within 72 hours of the injury), early subacute (2–3 weeks), and late subacute (approximately three months) stages of recovery. During each visit and at six months, clinical assessments were performed using the Rivermead Post-Concussion Questionnaire, with each item assessed on a five-point scale.

Twenty-eight patients completed at least one LLLT session, and none reported any adverse reactions. Also, the researchers found that they could measure the effects of transcranial LLLT on the brain.

The MRI studies showed statistically significant differences in myelin's integrity surrounding the neurons of treated patients versus the control group. Both these findings support follow-up trials, especially since there are no other treatments for these patients.

The study also showed that light does impact the cells. While it is well established that cells have light receptors, “going into this trial, we had several unanswered questions such as whether the light would go through the scalp and skull, whether the dose was sufficient, and whether it would be enough to engage the neural substrates responsible for repair after TBI,” says Gupta.

It’s important to note, and he adds that for this initial study, the researchers focused on patients with moderate traumatic brain injury. That helped ensure their study could have statistically significant findings because patients in this category are more likely to demonstrate a measurable effect.

“It would be much more difficult to see such changes in patients with mild injuries, and it is quite likely that in patients with severe brain injuries, the effect of light therapy would be confounded by other comorbidities of severe trauma,”

says Gupta.

He adds that researchers are still very early in the development of this therapy. It is unknown if it could be applied to other types of brain injury, such as chronic traumatic encephalopathy (CTE), which has received a lot of public attention over the last few years.

CTE is a progressive degenerative disease associated with a history of repetitive brain trauma such as that experienced by certain athletes, most notably football players.

This study opens up many possibilities for the broader use of photomedicine. “Transcranial LED therapy is a promising area of research, with potential to help various brain disorders where therapies are limited,” says Margaret Naeser, Ph.D., a prominent researcher in photomedicine and research professor of Neurology at Boston University School of Medicine. She was not affiliated with this particular study.

Source:

Massachusetts General Hospital

Journal reference:

Longo, M, G. F., et al. (2020) Effect of Transcranial Low-Level Light Therapy vs. Sham Therapy Among Patients With Moderate Traumatic Brain Injury. doi.org/10.1001/jamanetworkopen.2020.17337.

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Half a Trillion-Dollar Market  —  Men.

There’s an emerging disruptor in the beauty industry as companies target a different consumer type to expand the half a trillion-dollar market — men.

Across the globe, men’s adoption of beauty use is already starting to take off. But the trend comes in many different shapes and forms. For beauty companies struggling to find new avenues of growth, it’s a huge opportunity to see whether men are looking for traditional grooming products, discreet moisturizers, beauty balms, or popular light therapy.

According to Allied Market Research, the men’s personal care industry is predicted to hit $166 billion by 2022. According to market researcher NPD Group, just last year, men’s skin-care products alone saw a more than 7% jump in sales and with the category currently valued at $122 million.

“In recent years, the notion that men can’t or shouldn’t be using skin-care products or caring more in general about all aspects of their appearance has been receding,”

Said Andrew Stablein, a research analyst at Euromonitor International, in a research note.

The success of digitally native brands catered directly to men such as Harry’s and popular subscription service Dollar Shave Club reveal

“the average men’s grooming routine isn’t about just shaving, but can be aided by using skin-care products,”

Stablein said.

Even high-end designers like Chanel have jumped on the trend, launching its first made-for-men skincare and cosmetics line known as “Boy De Chanel” last September.

“It seems that mass players are trying to expand their market and gain share in a slowing market by growing their user base,”

Said Alison Gaither, beauty and personal care analyst at Mintel.

This includes tutorials from U.K. makeup artist Charlotte Tilbury and Rihanna’s Fenty brand, which have both put out instructions for guys who want to use makeup subtly for a more groomed appearance.

According to Coresight Research, the Asia Pacific market is now one of the fastest-growing regions for men’s grooming and cosmetic product use. Jason Chen, general manager for Chinese online retail site Tmall, told Coresight that “supply cannot meet the demand for male make-up products across China.”

However, recent data suggests the new generation of beauty consumers prefer a non-binary approach altogether. According to NPD’s iGen Beauty Consumer report, nearly 40% of adults aged 18–22 have shown interest in gender-neutral beauty products and holistic products.

“There are so many … [people] growing up with the idea that you’re not tied to the gender you’re born with,”

Said Larissa Jensen, a beauty industry analyst at NPD.

“Beauty is no longer what you’re putting out as ‘ideal beauty.’ Beauty can be anything, anyone, and any gender.”

In 2016, shortly after Coty acquired CoverGirl, the brand made history with its first-ever “CoverBoy” featuring popular YouTube makeup artist James Charles.

Charles recently found himself in a very public spat with Tati Westbrook, another YouTube beauty vlogger. Coverage of the feud, which began after Charles backed a vitamin brand that was a rival to Westbrook’s own, has been widespread and shows the influence these internet personalities have and how the business has evolved over the past two years.

While Charles may be having his struggles now, as he has lost millions of subscribers, the attention he originally received from CoverGirl sparked similar collaborations by major brands including L’Oreal, who featured beauty blogger Manny Gutierrez, known under the moniker Manny MUA, as the face of its Maybelline Colossal mascara campaign in 2017.

“I think a lot of people misconstrue a man wearing makeup as someone that is transgender or someone that wants to be a drag queen, but it’s not that,”

Guitterez, founder and CEO of Lunar beauty told CNBC.

“I think right now people are still intimidated by the aspect of it.”

Gutierrez’s makeup tutorials and product reviews have attracted nearly 5 million subscribers to his YouTube page. According to a note by the NPD Group, one setting powder product saw a 40% surge in sales after Gutierrez promoted it on his YouTube channel.

“It’s all about inclusivity and encouraging people to be a little more inclusive with both men and women,”

Said Gutierrez.

“I think that as time progresses and you see more men in beauty, it’ll get a little bit better and better.”



Red Light Therapy Can Help Reduce Inflammation

We can usually identify inflammation when we see it. The inflamed part of the body looks red and swollen, and it feels hot and painful. But in this article, we’ll find out why we experience inflammation, as well as its causes, risk factors, and how red light therapy devices can help reduce it.

What Really is Inflammation?

Inflammation is our body’s natural response to pain, irritation, damaged cells, exposure to germs, and potential danger. There are two types of inflammation:

1. Acute inflammation

This type of inflammation happens as our body’s healthy response to injury or stress. We mean “healthy” because it helps the body recover faster. The inflammation happens only for a few hours and then starts to repair the damaged tissue.

2. Chronic inflammation

On the other hand, chronic inflammation can be excruciating and may cause discomfort or inconvenience. It causes an imbalance in the body, making it operate inefficiently over time. Chronic inflammation can be caused by viral infections, repetitive tissue damage, autoimmune reactions, and persistent and recurring acute inflammation. At its worse, this type of inflammation may lead to more serious diseases and/or conditions such as cancer, stroke, depression, and heart disorder.

Common Causes of Inflammation

Anything that causes stress on your body may lead to inflammation. These include:

  • Bruises
  • Bumps
  • Burns
  • Chemical irritants
  • Dehydration
  • Diseases
  • Excessive alcohol
  • Infection
  • Irritants
  • Poor nutrition
  • Poor sleep
  • Splinters
  • Toxin exposure
  • Wounds and injuries

Signs of Inflammation

There are five common signs of inflammation:

  • Heat on the inflamed area
  • Loss of function (i.e., you can’t move your arms or legs)
  • Pain
  • Redness
  • Swelling
Treatment Options for Inflammation

For acute inflammation, doctors normally recommend nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and paracetamol. Meanwhile, chronic inflammation may also be prescribed with NSAIDs, along with steroids and supplements.

However, these common treatment options help prevent inflammation symptoms but do not deal with the root cause, including improper cellular function, biological imbalance, and damaged tissues. This is also why lifestyle changes (improved diet, regular exercises, and high-quality sleep) and red light therapy could be of great help.

How Red Light Therapy Works Against Inflammation

Red light therapy, also referred to as low-level laser therapy (LLLT) or photobiomodulation (PBM), is a non-invasive treatment option. This kind of therapy delivers wavelengths of red and near-infrared (NIR) light to your skin and cells for multiple benefits. When it comes to inflammation, it can help cut down oxidative stress and activate protective cellular mechanisms to boost your immune system and protect you from diseases that may cause inflammation. It can also boost the generation of healing agents and antioxidants in the body to speed up damaged tissues' healing process.

Red light therapy can give your body the light exposure needed to function more efficiently, improve blood flow, and limit inflammation.

Conclusion

Inflammation is a natural part of our biological processes, but chronic cases may also lead to serious health risks that can affect the quality of your life. Therefore, if you’re experiencing signs of inflammation, regardless if it’s acute or chronic, please schedule an appointment with your doctor to get the care and treatment you need as early as possible.

In the meantime, to protect your body from the stress that may cause inflammation, you can do red light therapy either through a health provider or from the comfort of your home. If you need to purchase red light therapy devices, you can browse through our catalog to see the brands and products that we offer.


Keep Your Skin Healthy with Red Light Therapy

Skincare doesn’t just affect the way you look. It also plays a huge role in your overall health — from body temperature to hormone regulation to your immune system. If you’re into skincare as much as we are, one of the many ways that can help you keep your skin healthy is red light therapy. In this article, we’ll take a deep dive into why you should take care of your skin, and we’ll also discuss how red light therapy devices can help you achieve your skin goals.

Are you ready? Let’s go straight into it.

Why Do You Need to Take Care of Your Skin?

As the largest organ in our body, your skin is your body’s first defense line to bacteria, germs, viruses, etc. It’s a vital part of the immune system and some processes in your body, such as temperature control, blood circulation, and hormone production.

Main Functions of the Skin

Let’s take a look at the skin's main functions to help you understand how essential it is for you to take care of this vital organ.

1. Defense and Immunity

The skin is an active immune organ, and it serves as our physical barrier from the dangers of the environment. It helps protect our bodies from diseases, germs, viruses, dirt, UV radiation, and potential thermal and physical injuries. It also helps detect and fight off infection, toxins, allergens, hazardous substances, and carcinogens.

2. Temperature Regulation

Aside from protecting us from extreme cold or heat, the skin also helps prevent moisture loss, keeping us from being dehydrated.

3. Sense of touch

The skin has a somatosensory system that is composed of touch receptors and nerve endings. This system is responsible for the sensations we feel, including pain, pressure, vibrations, smoothness, roughness, heat, cold, tickle, itch, and more.

4. Storage and Production of Vitamin D

Your body also uses your skin's deeper layers to store metabolic products, fat, and water. The skin is also responsible for producing vitamin D, supplied in the body when the skin gets enough sunlight exposure.

5. Beauty

Need we say more? Your skin plays a huge part in your appearance. Of course, when your skin is healthy, you also look glowing, radiant, and definitely more attractive.

Red Light Therapy and Keeping Your Skin Healthy

Before we proceed with the “how,” let’s first define what red light therapy is. Red light therapy is a non-invasive treatment option for different kinds of medical conditions. It is also used for health improvement and various aesthetic procedures.

Decades ago, red light therapy machines were only available in clinics, high-end salons, and spas. Nowadays, red light therapy devices can be bought and used by anyone. In fact, you can do red light therapy at the comfort of your home and incorporate it into your skincare routine.

How Does Red Light Therapy Work?

Red light therapy works by delivering wavelengths of red and near-infrared (NIR) light to our cells and skin. Besides helping enhance cellular function, red light therapy also helps stimulate the mitochondria and produce ATP (adenosine triphosphate) energy. This treatment option usually takes only about 10 minutes per session.

How Does Red Light Therapy Help Keep Your Skin Healthy?

Our skin relies on millions of cells to be able to perform its functions. When our cells experience homeostasis or a state of balance, our skin and body perform (and look) better. And as mentioned above, red and NIR light enhances cellular function while also preventing inflammation and oxidative stress. Red light therapy helps make your skin look and feel softer, smoother, and healthier.

Besides, red light therapy also helps damaged tissues heal and regenerate faster. It also has anti-inflammatory benefits, potentially increasing blood flow to damaged and inflamed tissues and reducing oxidative stress.

Final Thoughts

Skincare is self-care, as keeping your skin healthy also produces multiple benefits to your health. Thankfully, aside from proper hygiene, regular exercise, a balanced diet, and an established skincare routine, red light therapy can also improve your overall skin health.

For more information about red light therapy or to view our catalog of red therapy devices, click here.

Sources:

https://www.hse.gov.uk/skin/professional/causes/structure.htm

Red Light Therapy for Enhanced Cellular Function

The one thing we have in common with animals, plants, and other living organisms is that we are all made of tiny little cells. The intricate human body in itself houses trillions of cells. Without cells, there wouldn’t be any life on Earth at all.

In this article, we discuss cellular anatomy and cellular function. Here, we understand how light plays a role in the support and acceleration of cellular respiration.

What is a cell?

Think of cells as the basic building block of all living organisms. As the smallest unit of life, cells contain many parts, each with a different and specific function. The command center of the cell is called the nucleus that contains the human DNA.

As these cells combine to form into an organism, they become responsible for vital activities like nutrient intake, energy production, structure building, and hereditary material processing. They make sure that your body gets enough energy and nutrients to function 24/7.

What is ATP?

One essential activity that our cells do for us is by taking in oxygen and nutrients to fuel body energy. This energy unit that is converted by the cells is called Adenosine Triphosphate (ATP) Energy.

The ATP itself is a molecule packed with high energy that empowers cellular function. ATP is required by the body to do every activity. Other cells that do more strenuous activities like muscle cells would need more ATP than others. The ideal optimal cellular function would allow cells to produce and use enough energy to achieve body balance or homeostasis.

How is ATP produced?

The mitochondria are the powerhouses of the cell. They are responsible for the production of ATP. Aside from cellular energy, this double-membrane powerhouse does protein synthesis, cell signaling, and cell apoptosis. ATP is produced with oxygen (aerobic) or without oxygen (anaerobic), the former being more beneficial because it converts more energy. Thus, 95% of cellular energy goes through an aerobic process.

Our cells go through a process called Aerobic cellular respiration to convert oxygen, food, and water into the body’s energy currency, which is ATP. This process is a well-organized metabolic pathway that consists of four stages. Our bodies take in nutrients from the food we eat for the first two stages to convert them into carbon compounds. Then for the next steps, these carbon compounds are transformed into the energy that our cells use.

How does light therapy support cellular function?

Light can sometimes be less attributed to improve our body’s physiology. However, light has benefits that go beyond aesthetic and technological purposes. Just like how light plays a role in plants' photosynthesis, it also benefits human cellular function.

Red light therapy from Kaiyan Medical composes of Red and Near-Infrared Wavelengths that aid in the Mitochondria's function to produce more ATP energy. It works by increasing the number of Mitochondria in our cells and by boosting their function.

The electron transport chain heavily governs the cellular respiration process. Red Light therapy has photons that can boost the mitochondria to function better through the Cytochrome C Oxidase. It plays an essential role in the cellular respiration process by improving the cell's electron transfer process. In this way, more ATP can be produced by the body for an enhanced cellular function.

As mentioned earlier, oxygen plays an essential role in the cellular respiration process. The infamous Nitric Oxide can take the rightful place of oxygen to limit ATP production that causes stress and cellular death. Red light therapy also gets rid of a harmful roadblock to ATP in the dissociation of Nitric Oxide and the Cox. The photons from Red light therapy prohibits the production of nitric oxide.

The effect that Red Light therapy does on our body is that by improving cellular function, our body can achieve these benefits:

  • Improved blood Flow
  • Increased Energy Build up
  • Enhanced Healing Response
  • Reduced Inflammation
  • Reduced Stress
  • Balanced Cellular Function

As you do daily activities such as eating, drinking, walking, or working out, think of the massive role that your cellular system plays to make these activities possible. In this way, you can put conscious efforts into improving your cellular system through a healthy diet and lifestyle and by integrating Red Light Therapy.

References:

https://www.healthline.com/health/red-light-therapy#how-does-it-work?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215870/

https://www.medicalnewstoday.com/articles/325884

https://www.britannica.com/science/cell-biology

https://www.britannica.com/science/mitochondrion

https://www.nationalgeographic.org/media/cellular-respiration-infographic/

The Light for your Wounds

I remember how I used to come home with a bruise or cut every day after playing basketball in my childhood. Cuts and bruises were a part of the game, but my mother never took them lightly.

They may not seem like a tiny problem, but sometimes even a small wound can affect critical ways. It can lead to an infection as the cut exposes your body to external bacteria. This is why it important not to neglect the wounds.

What Happens When we Get a Cut?

Do you know what exactly happens when we get a cut?

In a small cut, the skin gets punctured, and the regular blood vessels get damaged. The effect is on the dermis layer. Whereas in the case of a deep cut, the impact is majorly on the tissues and the blood vessels break down completely results bleeding.

How our Body Reacts to Wounds?

When you get a cut, the body gets help from cells like neutrophils and immune cells. The section starts clotting the blood and reduces the blood flow. Antibodies, proteins clean up the site and eat the dead skin cells and other wastes.

Once the cut is free from germs, the skin growth gets started, and your body starts to rebuild the lost tissues and fix the broken blood vessels with the new ones. This repair work is done by cells called fibroblasts. In the last stage of wound healing, a lot of remodeling done to make the vessels and tissue functional again.

(Image source: https://askabiologist.asu.edu/)

The Light on the Wounds

No wonder science and technology have covered a long way to make human life easier. Now wounds can be treated with light therapy.

Yes, light therapy!!

That sounds out of the ordinary. But light therapy can heal your wounds by 200%!!

Wounds that Can be Treated by Light Therapy

Since wounds are of different types, wounds can be open or closed wounds. According to reports, LED light therapy can treat non-healing wounds, i.e., that doesn’t heal after 4 weeks. People with the following types of wounds can be healed from LED light therapy:

• Diabetic ulcers

• Venous ulcers

• Pressure ulcers

• Non-healing surgical wounds

• Serious burns

• Oral sores from chemotherapy/radiation

• Metabolic-disease-related wounds

• Wounds that repeatedly break down

How Red and Near-Infrared light Works for Wound

Light therapy a broad range of light having different wavelengths. Red light (620 nm — 680 nm) is visible red light, whereas Near-Infrared light (700nm — 1100nm) is invisible. Many studies reported that biologists have found that treating the cells with near-infrared light can grow 150% to 200% faster than cells not stimulated by light.

Biologically the Near-Infrared light boosts microcirculation and formation of new capillaries at the wound section.

Infrared light rays increase cellular energy that speeds up any healing process and penetrates deeper into the skin. As a result, the wound section receives more oxygen and nutrients to naturally help with the wound's healing process.

The light nurtures the lymph system activity. This assists with the detoxification process of the wound without overtaxing the lymph system and prevents lymphedema. The near-infrared rays also clean up the dead or damaged cells, making a clear blood circulation path.

Another benefit of Infrared therapy is that it helps release ATP (raw cellular energy), which gives energy to the damaged cells in the wound to heal better and faster (study).

Not only this, the studies have shown that the wound size also decreased by up to 36%.

Source: www.slideshare.net/amintalebi1/light-and-wound-healing

So, next time you encounter a wound, put a light on it!!

Let your cut heal through LIGHT THERAPY!

References:

http://www.jofamericanscience.org/journals/am-sci/am0706/36_5769am0706_203_208.pdf

https://www.infrared-light-therapy.com/red-light-therapy-wound-healing/

https://pubmed.ncbi.nlm.nih.gov/25363448/

https://pubmed.ncbi.nlm.nih.gov/25654197/

https://iopscience.iop.org/article/10.1088/1054-660X/24/8/083001

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126803/

https://pubmed.ncbi.nlm.nih.gov/24155549/

Animal Wellness: Red Light Therapy for Dogs

Certified pup parents know pets could easily sense when we’re feeling sad, happy, scared, or sick. Our furry friends could probably read us better than we could read them. However, active pets are also prone to injuries, cuts, wounds, inflammation, and infections like human beings.

If you’re a pet owner, you’d always want to give your pets the best care possible to make sure they are healthy and happy at all times. Thankfully, medicine has innovated well enough to find more advanced treatments and maintenance tools for our canine friends. In recent years, pet owners and some veterinarians have been using safe, non-invasive, and high-tech treatments for pets and domestic animals such as Red-Light therapy.

What is Red Light Therapy?

Red light therapy has been utilized by the veterinary world to deliver similar benefits to pets, just like humans. Red light therapy is a non-invasive treatment and a form of photobiomodulation that alters animal cells' physiology.

Light therapy produces wavelengths of photons that the photoreceptors in the animal’s bodies can absorb. The light provides alteration to the animal cells that result in numerous benefits such as better blood circulation and natural cellular regeneration.

Multiple studies support the efficacy of red-light therapy to animals. A 2017 study shows how Red Light therapy promoted faster healing for dogs that underwent bone surgery. The findings were also complemented by another study that suggests near-infrared wavelengths promoted bone cell reproduction for dogs.

Red Light Treatment for Dogs?

When our pets sprain their ankles or cut their pads, their cells become damaged. As a result, their bodies need cell energy in the form of adenosine triphosphate (ATP) to repair damaged cells and tissues.

The photoreceptors in their body absorb red light. The light stimulates ATP production in the animal’s body that results in faster delivery of nutrients and better excretion of toxins. All of these processes are essential for the body’s healing.

Red Light also promotes better circulation as it stimulates Nitric Oxide production to help blood vessels remain flexible. Injured or damaged cells need proper blood flow for healing. Light therapy helps in the healing process by increasing blood flow to ensure enough nutrients and oxygen in the affected area.

Red light is beneficial for surface healing by helping tissues that are potent in hemoglobin. On the other hand, near-infrared light can work better on deeper wounds as it can pass through the animal’s body's deeper tissues.

Innovators like Kaiyan Medical uses the FDA-cleared Red Light Therapy pad that utilizes the combined technology of Red Light-emitting diodes that can penetrate the skin and infrared wavelengths that can heal muscles, ligaments, and tendons. Red light and near-infrared wavelengths are the ideal combination of surface and inner healing.

Aside from providing the cells with energy, the light also stimulates collagen production, which aids in repairing damaged tissues. Collagen is an essential protein that can help get rid of scars and wounds.

What are the conditions that can be addressed by Red Light Therapy?

Skin and Surface issues

  • Surface wounds
  • Hair loss
  • Eczema
  • Other Skin Conditions
  • Wounds and Cuts

Deeper surface issues

  • Arthritis
  • Soft tissue injuries
  • Ligament injuries
  • Post-surgery Inflammation
  • Pain, Inflammation, and Swelling
  • hip dysplasia
  • Tendon problems
  • Strains and sprains
  • Salivary gland problems

General Maintenance

  • Maintenance of healthy joints and Bones
  • Maintenance of healthy Cardiovascular system
  • Maintenance of healthy Digestive system
  • Healthy Vision
  • Prevention of anxiety

Light therapy can be your best therapeutic tool in boosting your pet’s overall wellbeing. As a general rule, light therapy is a safe and non-invasive option for treating minor issues and maintaining their overall health. However, if your pet is undergoing more severe health problems, it’s best to consult your veterinarian for a more conducive treatment plan. While red light therapy is not a panacea for all your dog’s health issues, it’s a low-risk and pain-free option to complement treatments and to promote overall wellness for your beloved pet.

References:

https://www.jstage.jst.go.jp/article/islsm/13/1/13_1_73/_article/-char/ja/

https://onlinelibrary.wiley.com/doi/full/10.1111/vde.12170?deniedAccessCustomisedMessage=&userIsAuthenticated=false

https://www.thieme-connect.com/products/ejournals/abstract/10.3415/VCOT-15-12-0198

https://www.degruyter.com/view/journals/plm/1/2/article-p117.xml

https://onlinelibrary.wiley.com/doi/abs/10.1053/jvet.1999.0292?deniedAccessCustomisedMessage=&userIsAuthenticated=false

Deuterium and Red Light Therapy

As the most accessible element in the globe, hydrogen plays a huge role in our biological processes. However, you may not know that hydrogen usually brings an uninvited guest in your body, and we call it deuterium. Having high deuterium levels may change the chemical reactions in your cells and affect your bodily functions and metabolism, leading to unwanted health consequences.

What is Deuterium?

Deuterium is also known as a “heavy hydrogen” and is one of the two stable hydrogen isotopes. We commonly have it in our bodies — in fact, it helps children grow. However, adults may have too much deuterium because of dietary and environmental factors. As mentioned above, this may lead to chemical reactions at a cellular level and lead to health risks.

How Can Deuterium Affect Your Health Negatively?

Hydrogen is necessary for our day-to-day bodily functions. Our biological processes require it, and we usually get it from what we eat or drink. Upon intake, hydrogen goes to the mitochondria, also known as the powerhouse of the cells.

Our mitochondria can be compared to thousands of engines that continually run to produce the ATP energy we need to survive daily. The majority of people eat only three to five pounds of food each day, but we usually make more than 170 pounds of ATP energy at the same time.

On the other hand, deuterium is like hydrogen’s “evil” sibling. And we repeat, excess deuterium is harmful to our bodies. Because it is twice as heavy and large as hydrogen, it may damage the nanomotors in your mitochondria and slow down ATP energy production. As time goes by, the wear and tear on your nanomotors caused by the heavy hydrogen atoms may completely break your nanomotors. This damage may cause muscle pain, dehydration, impaired memory, poor sleep, headaches, and lymph nodes.

How Can You Measure the Level of Deuterium in Your Body?

Two “D-terminator” diagnostic tests can help measure the deuterium levels in your body. Advanced technology, such as magnetic resonance imaging (MRI), can also be used to visualize and track deuterium patterns in your body, whether it’s in your bodily fluids, DNA, or even your hair and nails. Based on these tests, your doctor will be able to determine your deuterium levels. And when it shows to be excessive, he/she may come up with a plan to deplete deuterium in your body.

Why Do We Get Overloaded with Deuterium?

We experience high deuterium levels because of what we eat or drink and some other environmental factors. For instance, carbohydrates, processed foods, and synthetic supplements contain high levels of deuterium. Tap, ocean, and river water also have high deuterium levels, so when you’re exposed to these things regularly, you may experience an overload of this hydrogen isotope.

How Can You Deplete Deuterium?

Nutrition is the baseline of depleting deuterium. Based on your test results, your doctor may recommend consuming food groups that contain lower levels of deuterium, such as proteins, green vegetables, and healthy fats. You may also be advised to drink deuterium-depleted water to lower your deuterium levels.

Health experts say that a body that functions properly can naturally regulate deuterium levels and produce healthy amounts of ATP energy.

How Does Red Light Affect Deuterium?

Red and near-infrared light can affect our body’s hydrogen bonds in a process quite similar to photosynthesis. The water inside our cells usually becomes less harmful when our bodies absorb wavelengths of red and near-infrared light between 600–950 nanometers. This helps with proper cellular respiration and helps increase ATP energy production in your body.

Changing the water's resistance in your body, red, and near-infrared light can help reduce the amount of friction at the cellular level, promote cellular longevity, and lead to higher outputs of good energy.

To learn more about the benefits of red light therapy or to see what kind of red and near light therapy devices you can use to lower your deuterium levels, click here.


More References

https://www.nature.com/articles/s41598-020-61983-3

https://doi.org/10.1038/s41598-020-61983-3

Wang, M.; Audi, G.; Kondev, F. G.; Huang, W. J.; Naimi, S.; Xu, X. (2017). "The AME2016 atomic mass evaluation (II). Tables, graphs, and references" (PDF). Chinese Physics C. 41 (3): 030003-1–030003-442. doi:10.1088/1674-1137/41/3/030003.

https://www.hindawi.com/journals/tswj/2018/5454367/

Answering FAQs About Hyperpigmentation

You might have heard about hyperpigmentation from your dermatologist or a skincare company. But if you didn’t completely understand this skin condition — and you want to know how it develops, how to remove it, etc. — or if you have questions about this skin condition, this article can be of help.

What is Hyperpigmentation?

Hyperpigmentation can be one or multiple skin patches or spots that appear much darker than your skin color. It is a cell mutation caused by changes in hormones, an injury like sunburn, acne, peeling from chemicals or any treatments, or inflammation. The darker areas of hyperpigmentation are excess deposits of melanin. And although it is harmless and common, having hyperpigmentation can make people more conscious about their looks. In fact, some people try to conceal it with cosmetic products, while some try to deal with it with professional help.

What are the Common Causes of Hyperpigmentation?

Age spots: As we age, brown, black or tan skin spots may develop on our hands, face, and/or head. These mostly affect light-skinned individuals and are caused by too much exposure from the sun.

Melasma: Usually caused by hormonal changes, melasma is common in women, especially those who are pregnant. It is composed of large patches of darkened skin that can appear on the face or stomach. Those with darker skin are more likely to have melasma.

Inflammation: This is caused by autoimmune reactions from skin conditions like acne and eczema or a skin injury. Post-inflammatory hyperpigmentation appears on the face and neck, and its appearance may vary depending on the skin tone. Inflammation can happen to anyone, regardless of skin color and origin.

How Can I Treat Hyperpigmentation?

There are different treatment options for hyperpigmentation, depending on your skin tone. Fair skin can be treated by most hyperpigmentation procedures, such as laser treatments and micro peeling. Medium skin usually reacts better with chemical peels and microdermabrasion therapy. Darker skin can benefit from using glycolic acid, kojic acid, microdermabrasion in a low setting, lower-strength chemical peels, and low-intensity laser treatments.

Some important things to watch out for when treating hyperpigmentation include:

  • Take a lot of vitamin C, an antioxidant that helps fight dark spots. Vitamin C helps prevent melanin production by inhibiting tyrosinase enzymes, causing lighten pigmentation and making normal skin brighter.
  • Another way to treat hyperpigmentation is to re-injure the skin's affected area, flushing the pigment to the surface.
  • There are topical creams or even home remedies (i.e., aloe vera, green tea, and licorice) that can be used to help heal hyperpigmentation. Some people find them effective, while others find other treatments with the same purpose as these treatments more effective. Red light therapy is one example.
  • Dark skin should be treated more carefully to prevent hypopigmentation, development of white spots that cannot be reversed.
Is Light Therapy Effective in Treating hyperpigmentation?

Photobiomodulation is another name for red light therapy. It may help the body produce more energy and regenerate the skin by using natural light. This can also be used on hyperpigmentation and other skin injuries like acne, inflammation, burns, and scars. When used consistently, light therapy is highly effective in reducing and healing hyperpigmentation patches and helping them return to normal pigment levels.

Red light therapy is a powerful, advanced relief for skin inflammation. Skin cells heal and rejuvenate better when exposed to healthy wavelengths of light, which can help treat hyperpigmentation.

Why is Red Light Therapy Better than Near-infrared Light Therapy in Treating Hyperpigmentation?

There’s a study that shows near-infrared light can help produce tyrosinase enzyme, which prevents melanin production. This helps patients with vitiligo stimulate melanocytes, the same compound in vitamin C that helps lighten hyperpigmentation. But the truth is, there is no clear clinical consensus among photomedicine researches about using near-infrared light for hyperpigmentation.

Red light wavelengths are considered to be safe as it does not stimulate the production of pigment. It creates healthy wavelengths of light to help the skin cells heal and rejuvenate naturally.

When can Results be Seen After Doing Light Therapy to Treat Hyperpigmentation?

Results can be seen after several treatments done per week. The level of skin improvement depends on how consistently you use red light therapy. Also, the more consistent and the more careful you are in the process, the better the results you can see. Be sure not to pick or touch the treated areas to avoid infection or irritation.

Conclusion

Light therapy, especially when combined with other treatment options, can greatly help remove hyperpigmentation. To learn more benefits of red light therapy, you may reach out to us. We offer safe and easy-to-use light therapy devices that physicians use both for aesthetic and medical purposes. Meanwhile, if you have more questions about hyperpigmentation, please reach out to your dermatologist.

More References

https://www.aocd.org/page/Hyperpigmentation#

https://www.healthline.com/health/hyperpigmentation

https://www.healthline.com/health/beauty-skin-care/hyperpigmentation-treatment

https://theskincareedit.com/red-light-therapy-benefits#:~:text=Red%20Light%20

How Saunas and Red Light Therapy are Distinct but Complementing

Saunas and red light therapy devices are clinically-proven treatments that complement each other wonderfully, even if they depend on distinct biological mechanisms to yield various natural health and aesthetic benefits.

In this article, we’ll focus on how things work for red light therapy and the distinctions of traditional saunas, and what you can actually gain by availing of either of them.

What You Need to Know About Saunas

Saunas can make your body’s core temperature hotter by supplying sufficient heat throughout your body. It has been a part of traditional medicine for various centuries, as the old century folks realized the health benefits of sweating. Although there are multiple types of saunas, two of them are the most popular:

  1. Traditional Convection Saunas

When you think of saunas, this is the first scenario that comes to mind: hot and steamy. This type of sauna requires more energy as it delivers heat to the atmosphere, warming the air inside the sauna, and distributes heat in the body. Traditional convection saunas can maintain air temperatures between 170–200°F and are an ideal type of sauna for general use. It is important to comprehend the different temperatures required for specific health concerns since being exposed to heat more than what has required triggers a warning for unsubstantiated claims.

  1. Infrared Saunas

The latest trend in saunas is the infrared saunas. Inside, instead of warming the air, this kind of sauna heats actual objects. Such objects include those with emitting surfaces, charcoal, and carbon fiber. Infrared saunas' effectivity is directly attributed to the temperature, humidity, and length of time your body is exposed to heat, even though many saunas claim to provide “full-spectrum” infrared wavelengths.

The farther the wavelengths are in the infrared spectrum, the more they are considered efficient and effective in heat production. This will be thoroughly discussed later, but the general gist is that heat supplementation is the primary purpose of saunas, convection, and infrared.

On the other hand, near-infrared wavelengths in near-infrared saunas generate very little heat. Most of the high-quality standard saunas use more effective heats from the far-infrared spectrum or IR-C wavelengths.

What are the Health Benefits of Saunas?

Inducing thermal stress on the body is the primary function of every sauna, but what does it really mean?

One of many biological responses from sauna usage is increased heart rate as well as perspiration. The essential body processes protein metabolism and is also affected by enough heat. Heat shock proteins are a special kind of protein that responds specifically to cellular stress from heat. Heat stress induction leads to natural health benefits like those we gain doing physical activities.

One experiment had participants sat in a sauna treatment for 30 minutes at 194°F for 3 weeks, totaling 13 work sessions. The results showed that the participants improved 32% in performance tests versus those who underwent sauna treatments.

Besides improving your cardiovascular functions, using saunas can help reap benefits such as detoxication, decreased depression, and lesser chronic fatigue.

Red Light Therapy vs. Saunas

What differentiates saunas from red light therapy devices is their mechanism of action. While saunas utilize heat for biological effects, red light therapy devices supply healthy light wavelengths directly to the skin and cells. Even when producing almost no heat, red light therapy devices help with cellular function improvement and support bodily balance. Simply put, red light therapy helps energize the body with light, while saunas heat your body.

How does red light therapy work?

Mitochondria, the powerhouse of our cells, is wonderfully affected by certain wavelengths of natural light. This helps in producing energy within the cells of our body, feeding photons to our cells from natural light via red light therapy.

What about clinically-proven wavelengths?

We feel warm when exposed to sunlight and other heat sources such as fire and hot coals because most of the wavelengths, including ultraviolet (UV), are rapidly absorbed by the outer layers of the skin tissue as heat.

However, unknown to many, some wavelengths have the unique capability of boosting your cellular functions and energy. These are those few wavelengths that can penetrate human tissues more effectively, having photons power-up your “cellular batteries.”

What to Look for When Buying Red Light Therapy Devices and Saunas?

One of the first few things you need to look for in saunas is the temperature it produces. You need to consider some other factors, including the type of wood, the heating unit (Is it conventional or infrared? Is it near far or full-spectrum?), finishes and stains, price, and more.

On the other hand, some of the factors you need to consider when choosing a red light therapy device are the device’s light energy output, light color or frequency range in terms of nanometers, warranty, body or treatment coverage area, the price, and the credibility of the company provider.

Light Therapy and Saunas: Friends with Benefits

Saunas and red light therapy devices offer a wide range of natural health benefits, which surprisingly go well with each other. They both support balance and health to improve your fitness and function but do not overlap with each other’s effects because of energy supplementation in distinct forms and wavelengths. What a great combination of complementary natural therapies!

Here at Kaiyan Medical, we provide different types of red light therapy devices for various medical, wellness, and aesthetic uses. To see our list of products, click here.

References:

https://www.health.harvard.edu/staying-healthy/saunas-and-your-health

https://www.healthline.com/health/fitness-exercise/are-saunas-good-for-you

Scoon GS, Hopkins WG, Mayhew S, Cotter JD. Effect of post-exercise sauna bathing on the endurance performance of competitive male runners. Journal of Science and Medicine in Sport. 2007 Aug.

Crinnion WJ. Sauna as a valuable clinical tool for cardiovascular, autoimmune, toxicant- induced and other chronic health problems. Altern Med Rev. 2011 Sep.



Let’s Talk About Optimal Performance Recovery and Red Light Therapy

Performance and recovery go hand in hand when training or doing physical activities, regardless if you’re an athlete or not. In fact, athletes and their trainers utilize light therapy to improve their performance and muscle health and optimize recovery. To expound further, this article will tackle optimizing performance in fitness, improving the recovery process, and breaking down the significance of light therapy.

Optimizing Performance and Improving Recovery

Optimizing performance means paying attention to the body and how it functions, to live and train the body, and to find the best way to support its functions. Performance is not based on how hard or heavy are the weights you lift or the number of kilometers you’ve run; it is how effective your performance is and how you match it with your lifestyle (with the way you eat, drink and sleep).

On the other hand, recovery is about the effectiveness of the body’s healing process and the conscious effort of being in your best shape by enhancing your workout. It is also about utilizing the body’s tools and functions to effectively finish the jobs required daily.

Physical Performance and Recovery

Performance and recovery are correlated to one another. In exercising or training, if you want to improve fitness, workouts should be consistent. To get stronger, faster, and bigger, certain efforts must be made to increase performance levels. The recovery process is essential in health. It contributes to the workout; it is the downtime between training sessions or a break due to an injury or a period of healing from any exhaustion experienced.

Breaks like cool-downs, rest, and ample time of sleep give your body time to recuperate. They also allow healing for the muscles and tissues affected, strained, or damaged from workouts or training.

Performance is better when recovery time from soreness or inflammation is maximized. It also helps prevent burnout, fatigue, and possible injuries. If recovery is not made right, your physical performance may not reach its optimal state. Some athletes and trainers even make a recovery a priority over training itself. They believe that when an athlete recovers better than their competition, they will train harder in the long run.

Recovery is for Everyone

Even if you are not an athlete, you should know how to let your body rest, heal, and recover properly from any form of injury or physical activity. Everyone has their own activity levels to maintain. It may not be sports-related, but everyone demands effort from their bodies on a day-to-day basis.

When Recovery is Not Prioritized…

Regardless if you are an athlete, your body has limits. And if you push too hard, the body can break down and perform worse, especially if you didn’t observe any recovery time. Overtraining and pushing the body beyond its limits can affect performance in the short term or long term. Chances of injury are higher when you don’t allow yourself to recover, and it may also affect hormonal levels and the function of the immune system. The body needs time to process inflammation or any injury.

Inflammation and the Importance of Recovery

Inflammation happens when the body responses to danger or strain. It often takes place during a strenuous workout. When exercising, inflammation may indicate muscular damage. And when a muscle is “damaged,” it means that the tissue is growing and undergoes repair to get stronger.

Experiencing inflammation is a normal part of the growth and repair of muscle tissues. However, if you won’t set aside time for recovery, your inflammation may worsen over time and lead to greater health consequences.

4 Easy Ways to Improve the Recovery Process

Here are some ways that can help you improve your body’s recovery process:

  1. Body awareness

The body speaks when it sends signals to the brain. Sometimes, we dismiss these signals because of training goals. This may eventually lead to fatigue and injury. When you experience pain or when your muscles are sore, it is important to give your body time to recuperate. You must also be aware of your heart rate, especially at rest, as it may be saying something about the state of your health.

  1. Getting enough sleep

Besides giving your body time to recuperate, deep sleep also allows the body to digest and process fat and recover from inflammation or damaged muscle tissues. It is harder for the body to recover from pain, strain, fatigue, and injury when you’re sleeping less than 7–8 hours per night. If you’re struggling with getting enough sleep, try doing meditation or speak with a doctor so he/she can advise you about developing a sleeping routine.

  1. Eating a balanced diet.

Getting the right amount of whole foods, good carbohydrates, protein, and good fat can also boost your performance and recovery. Lowering your intake of processed foods, alcohol, and sugary drinks can also help decrease inflammation.

  1. Aiming for balanced and healthy cells

The performance and recovery of our bodies depend entirely on our cells. When our cells are creating and using energy efficiently, our bodies recover faster. ATP (adenosine triphosphate) energy is released to give us power in what we do. The process of creating ATP energy works best when our body and cells are well-balanced, reaching a state called homeostasis.

Light Therapy, Performance, Healing, and Recovery

High-quality devices are now available in the market to help athletes and trainers enhance the body’s natural healing and recovery process through light therapy.

Light therapy is a non-invasive treatment that uses LED lights to deliver red and near-infrared light to the skin and cells. It promotes efficient cellular ATP energy production and helps restore the balance of cells and tissues. Light therapy can be done before or after a workout. Some even do it both times — before and after a workout, depending on their goals.

Pre-conditioning with light therapy before working out can also help strengthen muscle performance. It can limit muscle damage and strain, lessening the chances of inflammation or soreness. When used after a workout, it promotes the speedy recovery of muscles and accelerates its adaptability to exercise. It also helps the body process acute inflammation after physical activity.

The Relationship Between Light Therapy and Muscle Cells

Muscles are composed of millions of cells that need to release ATP energy to fulfill the body's jobs, balancing exercise and stress. Light therapy helps improve cellular ATP energy, glycogen synthesis, oxidative stress reduction, and protection against muscle damage from exercising. Light therapy also helps improve blood circulation and oxygen availability, which allows better healing and recovery. It helps with the overall improvement of physical performance and faster recovery times. It also helps limit fatigue from exercising and strength training.

Recover and Improve Your Performance with Light Therapy

As discussed, light therapy promotes faster healing and recovery and soothes cells under stress when doing strenuous workouts, incurring injuries, and experiencing inflammation. When you set aside time for recovery, you give your body and cells what they need to function, thus improving your overall performance.

At Kaiyan Medical, we offer high-quality light therapy devices to help you achieve and maintain your fitness and performance goals. If you have questions about our products and the brands we offer, please don’t hesitate to contact us. We will respond to you as soon as possible.

Red Light Therapy For Hair Loss

If you’re one of the 35 million men or 21 million women in the United States who are losing their hair, you know how hard it can be to slow down getting bald. Creams, pills, and other treatments are often touted as solutions, but even if they do work, they come with side effects. Meanwhile, hair loss takes a tremendous mental toll. Among the most common effects are diminished self-esteem and confidence, as you notice others wearing hairstyles you couldn’t possibly pull off. And while some people rock the bald look, it’s not for every guy suffering from male pattern baldness and it’s rarely an option for women.

If this sounds like you, red light therapy is worth a look. Red light therapy for hair loss is backed by research, is completely natural, and can slow–or in some cases, reverse–hair loss without disruptive side effects. If you’re curious how this is possible, what the most relevant studies say, and–more importantly–if it will work, this article is for you. From cellular growth to the proper how-to steps, read on to uncover how red light can help you get your hair back.

Why Do We Lose Hair?

According to the International Society of Hair Restoration Surgery, almost half of men show noticeable hair loss by reading middle age. Surprisingly, the numbers are even higher among women: by the age of 60, nearly 80 percent of women show noticeable hair loss.

So, why do we lose hair? Briefly, losing hair helps us making room for new growth. A typical human will have up to 100,000 hairs on their head, and it’s only normal to lose 50–100 every day. After that, that causes get more complicated.

A few of the most common causes include:

Genetics

The most common cause of hair loss is hereditary hair loss or androgenetic alopecia. Male pattern baldness is characterized by M-shaped hair loss that begins at the temples and a bald spot in the back. It can begin as early as puberty or later in life. Female pattern baldness generally manifests as thinning on the head's top and crown, widening the center part but not affecting the front hairline.

Stress

Both acute and chronic stress contribute to hair loss in men and women. In acute stress, hair loss is often tied to a specific cause such as a sudden loss of a loved one, an accident, illness, or surgery; this hair loss may be temporary. Chronic stress, including job stress, relationship stress, and financial stress, also appears to accelerate hair loss.

Poor Nutrition

Specifically, inadequate protein intake affects hair follicles and contributes to hair loss. While over 40 million Americans are malnourished due to poverty, easy accessibility of junk food means that while many Americans get enough calories in their diets, they do not necessarily get the nutrition they need.

Red Light Therapy for Hair Loss


Given the side effects, cost, limited success, and ongoing hassles of these common hair restoration treatments, it makes sense to look at an alternative that is painless, non-invasive, has no side effects, and can actually enhance your health in a variety of different ways at the same time. Red light therapy is that option. Also red light therapy can help improve various other conditions, including joint pain from arthritis, sun damage, and nerve damage, to name a few. In fact, it can even treat one of the root causes of hair loss: thyroid problems.

What Is Red Light Therapy?


Red light therapy is a phototherapy that uses specific wavelengths of light to reduce inflammation, accelerate healing, and promote a healthy skin tone. Red light is part of the visible light spectrum (not to be confused with infrared light or ultraviolet light, invisible to the human eye) and is bioactive in humans. This means that our bodies respond to it beneficially in much the same way that plants respond to sunlight: by creating more energy at the cellular level.

Red light (also called low-level light therapy or LLLT) for hair loss was discovered somewhat by accident in the 1960s when mice were given chemotherapy. The chemotherapy-induced hair loss, but when the mice were irradiated with red light, the fur grew back thicker than before. Modern red light therapy works similarly, using high-power LEDs to saturate your body with wavelengths of therapeutic light. It typically uses visible light in various colors, but the red and infrared ranges are best for a wide variety of conditions, including hair loss. While sunlight provides a complete spectrum of wavelengths (including red light), it also contains harmful UVA and UVB wavelengths. Using the red light frequency alone has no side effects, such as burning or skin damage.


How Red Light Therapy Restores Hair


Red light is especially effective at treating hair loss; specifically, light in the 620nm (nanometer) to 660nm wavelengths work best. It works by increasing blood flow in the scalp; this stimulates the metabolism in hair follicles, resulting in more hair production.

You lose hair during hair loss but not the follicles–the tube-like formations that anchor hair to the skin. At the base of each follicle is the hair bulb (the whole thing looks somewhat like a tall vase). At the bulbous part of the vase are the papilla and the matrix; this is where hair begins to grow. We see as “hair” mostly a protein called keratin that makes up the hair shaft. When the hair follicles and the papilla and matrix cells are not functioning properly, they cannot support hair growth,, causing it to slow or cease altogether.

Red light penetrates the skin to the base of the hair follicles, stimulating the cells, papilla,, and matrix to produce more energy, which results in these cells replicating more successfully. This replication leads to new hair growth from these previously-dormant follicles. Red light also:

Stimulates Adenosine Triphosphate (ATP) production, a coenzyme responsible for fueling cellular structures. Increases in ATP cause individual cells within the hair follicle to increase their activity, including the rate at which they replicate. Restoring the energy of the hair follicles' cellular structures means the papilla creates more keratin, which results in hair growth.

Increases collagen production. Hair is primarily made up of a protein called keratin. While collagen — another type of protein — isn’t present in hair, it acts as an antioxidant to fight damage caused by free radicals (compounds that develop in the body during stress, environmental pollutants, poor nutrition, etc.). Free radicals damage hair follicles, which contributes to their inability to grow hair. Increased collagen means less oxidative damage, which can lead to increased hair growth.

Increases the creation of new capillaries, which improves blood flow to the scalp and brings oxygen and nutrients to hair follicles,, and removes waste that can lead to hair follicle damage. One study linked improved blood flow to the growth of thicker, healthier hair. Barbers have long encouraged men to massage their scalps to increase blood flow, but increasing blood flow using red light is generally more effective.

Cases Where Red Light Does NOT Work

It’s important to note that while red light therapy is effective for many types of hair loss (especially alopecia or temporary hair loss due to hormonal imbalances or illness), it’s not effective 100% of the time. For example, hair loss due to chemotherapy will continue until the treatment is stopped. The same applies to hair loss due to the side effects of other medications. Also, any hair follicles that have been destroyed due to injury, surgery, burns, or other permanent injuries will not grow back. And remember, please see your doctor if you experience sudden or dramatic hair loss, which can signal a serious underlying condition. Red and Near-Infrared Light: a Potent Combination

More References

https://pubmed.ncbi.nlm.nih.gov/30843235/

https://pubmed.ncbi.nlm.nih.gov/29957664/

https://pubmed.ncbi.nlm.nih.gov/29797431/

https://pubmed.ncbi.nlm.nih.gov/28328705/

https://pubmed.ncbi.nlm.nih.gov/25124964/

Blue Light Therapy for Acne: Does it Work?

Having acne-prone skin can be incredibly frustrating, especially when your oral and topical treatments don’t seem to work well enough. Skincare ingredient junkies know actives that target acne problems such as salicylic acid and benzoyl peroxide can be a few of the most irritating ingredients that you can put on your skin- especially when used in hefty amounts.

If you’ve been wallowing into these-but to no avail, you might ease your frustrations by learning about what Blue Light Therapy can do to acne problems.

What is Blue Light Therapy?

Blue Light therapy is a form of phototherapy that uses a visible light device that has been used by dermatologists for decades as a clinically proven treatment for acne.

The treatment is considered a generally safe, non-invasive, and pain-free procedure with no downtime. Besides being a popular anti-acne treatment, Blue Light therapy has also been shown to remove stubborn acne marks and sunspots. It eliminates free radicals caused by exposure to harsh environments that may oxidize and age your skin.

One significant impact of Blue light therapy is that it has been used to treat skin cancer in patients with actinic keratoses at University of Iowa Hospitals & Clinics. The American Academy of Dermatology considers Blue light therapy a promising treatment for numerous skin issues like acne.

How effective is Blue Light Therapy Work for Acne?

Blue light has been shown to have an antimicrobial effect that penetrates deep into the skin’s pores to eliminate the acne-causing bacteria, otherwise known as Propionibacterium acnes, or P. acnes. Blue Light has been proven to have an antimicrobial effect, making it an ideal treatment to effectively kill several types of bacteria in your pores and oil glands responsible for causing breakouts.

A clinical study shows that 77% of people with acne-prone skin treated with blue light therapy for five weeks have seen significant changes in their skin. Another research suggests that at-home blue light therapy has reduced acne lesions on people who have used the therapy for 28 days.

Unlike other topical treatments that address inflammation, blue light therapy targets breakout-causing bacteria in your pores and by healing the skin from within. Blue Light Therapy is a form of defensive treatment to acne by eradicating bacteria that causes redness and inflammation and a proactive solution to preexisting acne.

Who is a good candidate for Blue Light Therapy?

Experts at the American Academy of Dermatologists agree that blue light therapy works best for people who have mild to moderate acne problems. It is also a great treatment to eliminate acne scars. Blue light therapy works by addressing the acne issue from its core. It works by removing preexisting mild to moderate acne while preventing sebum build-up that causes the inflammation. Severely too deep abdominal cystic acne may benefit from other prescriptive medications that target more serious skin problems. People who incorporate Retinols in their skincare routine may also want to avoid getting Blue Light treatments as such ingredients make the skin very sensitive.

What Blue Light Devices should I use?

Although many dermatologists use current clinical studies, there are available at-home blue light therapy devices that effectively treat acne problems.

The best Blue Light Devices should be FDA- cleared, just like our Blue Lights Therapy Beauty Skin Complexion Handheld Device and Aduro Mask, that is made with medical-grade quality. FDA-cleared at-home devices have innovated into using the same technology that delivers satisfactory results for acne-related problems.

Blue Light therapy works best as a treatment for acne when used consistently. A weekly maintenance appointment to your dermatologist’s clinic for a blue light treatment may cost you $100, which makes it a much more expensive endeavor than investing in at-home devices.

Portable blue light therapy devices can be more beneficial for you as they can be used more frequently as an addition to your skincare routine at a lower price point.

The best blue light therapy devices in the market provide a safer alternative to other harsh treatments for acne that may require risks such as scarring and irritation. If you want to know more about effective light therapy treatments, check this out.

Now you can add a cool, avant-garde addition to your skincare that can be a very convenient and effective treatment for your stubborn acne problems.

References

https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/radiation/photodynamic-therapy.html
https://www.medicalnewstoday.com/articles/319254
https://uihc.org/health-topics/blue-light-therapy-warding-skin-cancer
https://www.healthline.com/health/blue-light-therapy

Putting the Light on Psoriasis

Psoriasis is an autoimmune inflammatory skin disease where the skin cells build up and form scales and itchy, dry patches over the surface. It is a misunderstood skin condition. The misbelief is that it not treatable and affects a particular gender or at a certain age. However, it can affect both men and women equally, and more than 5 million adults deal with this skin disorder — which is about 2% of the U.S. population.

Another common misconception is that it is contagious and can spread from one person to another. Well, Psoriasis is an immune system problem in which your immune system does not work as it should normally do.

Light Therapy: The Advanced Way

With some options available for Psoriasis, light therapy is one of the oldest, safest, effective, convenient, and highly preferred treatment by dermatologists. It has been widely used to treat stable psoriatic lesions, including different parts like the trunk, scalp, arms, and legs, and partial nail psoriasis. The treatment of light therapy is available in a variety of light with different mechanisms of action. Based on the bandwidths, the varied versions includes ultraviolet B (UVB), psoralen ultraviolet A (PUVA), pulsed dye laser (PDL), photodynamic therapy (PDT), intense pulsed light (IPL), light-emitting diodes (LED), etc.

How it Works

Light therapy has a very long history of dermatological benefits. Psoriasis happens when the skin cells there is an abnormal production of skin cells. Light therapy works by slowing down the excessive production of skin cells on the epidermis layer. This reduces plaque formation. It also reduces inflammation and limits the growth of skin cells by affecting the functioning of the DNA.

Many clinical studies and researches have displayed positive and effective result in the treatment of various types of Psoriasis like –

  • Small areas of stubborn, thick plaque psoriasis
  • Palmoplantar psoriasis (on hands and feet)
  • Nail psoriasis
  • Scalp psoriasis

Why do Dermatologists Prescribe Light Therapy?

Light therapy treatment can:

  • Slow down the growth of abundant skin cells
  • Repress the functioning of an overly active immune system
  • Reduce inflammation and allow the skin to heal itself
  • Reduce or eliminate the dry and itchiness

Light Therapy Mechanism

Light therapy can be delivered on any affected skin areas such as the hands or scalp, or across their whole body. But proper care and protection are given to the skin areas, such as the eyes and genitals, before treatment.

The treatment doesn’t work in on-go. Several sessions are required as the effect is gradually seen in patients. The treatment requires multiple sessions where the amount of light is gradually increased per session. The light exposure is not instant and varies for a different duration depending on the skin condition severity.

The sessions give proper time to heal the skin. Usually, the sessions go from two to three months. We need to understand the fact that every person’s skin reacts to light therapy differently. Hence, how much improvement one sees in their psoriasis symptoms and how long those benefits last depends totally on their system.

Now the time has changed, and technology has brought more convenience in getting the treatment. Kaiyan Medical provides you numerous products that you can use at your home and enjoy your daily activities without getting disturbed. Break the old and mainstream treatments and adopt effective light therapy to let your skin and life heal completely!

References:

The Effect of Green & Red Light Therapy on Hearing

Low-level laser therapy

Low-level laser therapy (LLLT) has been practiced for over 20 years in Europe and has been introduced in the United States as a treatment for pain and postsurgical tissue repair. It has been proposed that laser energy in the red and near-infrared light spectrum may aid in the repair of tissue damage. A proposed mechanism for this therapeutic effect is the stimulation of mitochondria in the cells to produce more energy through the production of adenosine triphosphate.

Studies in humans have investigated the effects of LLLT on both hearing loss and tinnitus, with equivocal results. Some studies have found an improvement in hearing thresholds and tinnitus symptoms.

The Subjects

A total of 35 adult subjects were enrolled in the study. Two subjects withdrew from the study due to loss of interest and/or scheduling difficulty. The data from three additional subjects were not included in the analysis. One subject yielded unreliable audiometric and speech understanding data, speech scores could not be obtained from one subject with a profound hearing loss, and calibration problems compromised data from the third subject. Data from the remaining 30 subjects were included in the analyses. The experimental protocol was approved by the Institutional Review Board of The University of Iowa, and written informed consent was obtained from all participants.

The Device

An Erchonia EHL laser was used to provide the laser stimulation. The device was a portable unit that consisted of a hand-held probe and a main body. The probe contained two laser diodes. One diode produced light in the green part of the visible light spectrum (532 nm wavelength), and the other diode produced light in the red part of the visible light spectrum (635 nm wavelength). Both diodes produced energy levels of 7.5 mW (class IIIb). The laser beams from both diodes were dispersed through lenses to create parallel line-generated beams, rather than spots. A second Erchonia EHL device served as the placebo. It was identical to the treatment device, except that the laser diodes were replaced with nonfunctioning standard light-emitting diodes.

The Groups

The study used three groups: treatment, placebo, and control. Subjects were pseudorandomly assigned to one of the three groups.

Initial group assignment was random with occasional adjustment to ensure that the three groups were similar in terms of number of participants, female/male ratio, mean age of participants, and mean pure-tone audiometric thresholds. The treatment group received the laser treatment protocol using the functional laser device. The placebo group also received the laser treatment protocol, but using the nonfunctioning laser device. The control group made similarly timed visits to the laboratory but received no real or feigned “treatment.” The study used a repeated-measures design, with each subject taking a battery of pretests, followed by treatment followed by a battery of posttests.

Analysis

Data were obtained from both ears of each subject. Since no obvious differences were seen between left and right ears, data from both ears were combined in the following analyses. Strictly speaking, this likely violates the statistical assumption of independent sampling, since the test results from left and right ears of a single subject are likely to be highly correlated. None of the statistical tests used in the analyses are robust to the assumption of independent sampling, and the effect of including both ears is likely to be that of artificially increasing the sample size, making it more likely that a statistically significant result will be found. All statistical tests were conducted using a significance level of .

Conclusions

No statistically significant effect of LLLT on auditory function was found, as assessed by pure-tone audiometry, speech understanding, and TEOAEs in this test. Additionally, no individual subjects showed any clinically significant change. It remains possible that other methods of LLLT could have an effect on hearing. The type of device used was not the best one for this type of study. Further research elucidating the anatomic and physiologic bases for therapeutic effects of LLLT on hearing are needed before further clinical testing is warranted.

More References

Clinical Study | Open Access. Volume 2013 |Article ID 916370 | https://doi.org/10.1155/2013/916370

ClinicalTrials.gov (NCT01820416)

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How to Prevent Jet Lag with Light Therapy

How to Prevent Jetlag with Light Therapy Treatment

Globetrotters know flying across time zones can be all fun and games until headaches start to kick in, sleep cycles get disturbed, and frequent moments of inappetence prevents them from enjoying even the most sumptuous local cuisine. If you’ve had any of these unfortunate events disturb your travel plans and work productivity, you’ve most likely experienced a jet lag.

What is Jet Lag?

Jet lag, also known as jet lag disorder is our body’s reaction to abrupt changes in new environments that are two or more time zones ahead/delayed. This can affect even the most seasoned flyers like pilots and business travelers.

What causes Jet lag disorder?

Your body has a clock system called circadian rhythm that schedules your body for its sleep and wake up time. Your circadian clock is synced depending on your original time zone.

Jet lag is caused by a temporary discoordination with your circadian clock and your new time zone or sleep-wake schedule. This is why when you expose your body to abrupt schedule changes, its normal functions related to sleep, coordination, and gastrointestinal processes are disrupted. While your mind may be ready to fly west, your body may still be stuck home and is still hours ahead.

Treating Jet Lag with Light Therapy

Jet lag can take days, weeks, or longer to improve, which may affect daily activities. In addition, although jet lag may be a temporary disorder, frequent exposure also poses significant long-term risks such as disturbances in menstrual cycle, cognitive defects, and temporal lobe atrophy.

One popular and effective treatment for jet lag disorder is Light therapy. Light therapy has been considered as a popular and effective treatment for jet lag disorder and has been backed by research since 1980.

Your body clock is largely influenced, among other factors by light, which is indicative of the rising and setting of the sun. This means that adjusting to a new time zone also means adjusting to a new daylight-night time and awake-sleep schedule.

Essentially, light therapy assists your brain and body in adjusting to a new time zone by conditioning yourself to light at an appropriate time. This allows your normal body functions to be in sync with your new schedule. By regulating light exposure, you can adjust faster with new conditions.

Studies show that exposure to light therapy helps people adjust their circadian clocks to new time zones more efficiently and effectively. Treatment of jet lag by Light therapy involves an exposure to natural or artificial light such as red light therapy.


How does Red light therapy work?

Red light therapy is a non-invasive, quick and easy treatment for jet lag that brings concentrated natural light to your body cells in order to condition it for a new day-light schedule. Red light therapy emits natural light that can boost cell energy without the putting your body at risk of the damaging UV rays from the sun.

If you travel westwards, you can use Red Light in the evening to help you adjust to a later time. On the other hand, if you travel eastwards, you can expose yourself to red light in the morning in order to acclimate your body to an earlier time zone.

Kaiyan produces high-quality Red light therapy home devices that utilize medical-grade LED (Light-emitting Diode) in order to produce a natural red light that is ideal for adjusting to new time schedules.

The great thing about this device is that, if you often work away from sunlight, this indoor light therapy device can be a convenient way to adopt your circadian clock to a new time zone. Check out our top picks for the best FDA-cleared light therapy masks.

Experiencing jet lag may be the ultimate bummer for travelling, but sufficient knowledge and proper treatment can keep you away from ruining your travel plans and goals.

References:

https://www.scientificamerican.com/article/how-to-prevent-jet-lag/
https://www.mayoclinic.org/diseases-conditions/jet-lag/diagnosis-treatment/drc-20374031
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829880/


Why Hollywood Stars Love Light Therapy

Julia Roberts Uses LED Face Mask | PEOPLE.com
Julia Roberts using LED light therapy mask

From the red carpet to the spotlight stage, Hollywood’s stars are no strangers to the powerful power of light. Their skin is glowing thanks to the latest light-based skin treatment. Stars like Julia Roberts, Kate Hudson, and Jessica Alba have been sharing their experience with LED light therapy masks that are designed to boost collagen, reduce inflammation and banish acne-related bumps and scars.

In Kaiyan Medical we can develop your own beauty light therapy mask worth of the celebrities’ skin.

Kate Hudson using LED light mask
How it Works

These amazing light masks are recommended by dermatologists and estheticians who credit the masks’ multi-colored UV-free wavelengths with improving clients’ complexions.

“Tiny particles of light are called photons, which cells absorb and transform into ATP (adenosine triphosphate), the form of energy that cells use to carry out normal functions,”

says L.A.-based celebrity facialist Shani Darden.

“ATP is then used to power the metabolic process and repair and regenerate cells.”

In short, just like LEDs have been proven to encourage plant growth (what’s a greenhouse without a good grow light?), LEDs can have a similar stimulating effect on skin cells by jump-starting the rejuvenation process.

But not all lights are created equal. Different wavelengths of light have different benefits.

“Blue-light wavelengths destroy bacteria in the skin to improve acne,”

says Toronto-based cosmetic dermatologist Dr. Martie S. Gidon. It’s worth noting that LED therapy is not effective at treating hormonal acne and is only recommended for inflammatory acne — in other words, pimples caused by bacteria — and works best when paired with topical acne medication.

Anti-aging benefits

For anti-aging results, red light therapy is for you.

“Red-light wavelengths penetrate more deeply than blue light and stimulate fibroblasts to produce collagen, resulting in tighter skin and smooth fine lines,”

says Dr. Gidon, who also praises the red light’s anti-inflammatory effect for use post-facials and peels. Another light used in combination with the other two is infrared.

“It accelerates healing and encourages greater product absorption,”

says Shani who recommends clients use a combination of both blue/red light therapy and infrared.

Home LED masks have been growing in popularity, especially with the COVID restrictions. You can opt for flexible home masks for personal use or well, the spa line which packs more lights and cover a bigger zone. With so effective results, it’s no wonder stars like Michelle Williams and Rachel Weisz are opting to lay down inside LED beds in order to treat their entire bodies to the rejuvenating powers of the lights.

If you have question on how to create your own beauty mask, don’t hesitate in contacting us. We will guide you in the whole creative process.

More References


https://ca.hellomagazine.com/health-and-beauty/02017032134254/guiding-light

https://www.womansworld.com/posts/celebrities/julia-roberts-light-therapy-mask

When it Comes to Headaches, Light (Except Green Light) Triggers Pain

One of the Most Disabling Illnesses in the World

Migraines are considered one of the most disabling illnesses in the world,  most of whom are unable to function normally during a migraine. Migraines are much worse than the common headache - bringing on excruciating pain and other symptoms like dizziness, blurred vision, or vomiting.

Green light therapy lamps have been recommended by Harvard Medical School headache specialist Rami Burstein who found that light exacerbates migraines. Photophobia (extreme sensitivity to light) is associated with more than 80% of migraine attacks - but the green light in his research is different. He found that a narrow wavelength of green light is less aggravating than other colors because it sends a smaller, less disruptive signal to the brain via the visual cortex.

Stueids have been recording of dura- and light-sensitive thalamic neurons in rats to show that green activates cone-driven retinal pathways to a lesser extent than white, blue and red; that thalamic neurons are most responsive to blue and least responsive to green; and that cortical responses to green are significantly smaller than those generated by blue, amber and red lights.

"It became apparent that we should be able to use a narrow band of green light to treat photophobia," Burstein says.

Now patients could put their kids to bed, read a book, or enjoy a hearty meal with friends - instead of being isolated in darkness. Not only did green light fail to trigger pain, his research even found that it has a soothing effect.

Can Green Light Relieve Other Pain?

Padma Gulur, who does not work with Burstein, is looking into the possibility that green light might relieve other forms of pain besides migraines. Already one year into a clinical trial - testing the effects of green, blue, or white light on people's post surgery or fibromyalgia pain experience - Gulur says the data looks promising that green light therapy could provide benefit to those in pain. Gulur, a Duke University anesthesiologist, says that finding a way to reduce pain without drugs is essential, given the addictive nature and side effects of opioids and other pain relievers. Not only did green light fail to trigger pain, his research even found that it had a soothing effect.

"We have very few options that are safe, easy to comply with, and have an impact on the pain experience. So it was a quest for non-pharmacological options that could help patients in pain that led to looking at the potential for light-based therapy," she says

Mohab Ibrahim, an anesthesiologist at the University of Arizona, found that when rats were exposed to green light, they felt less pain - or, at least, they were able to tolerate more discomfort in the form of heat or pressure. Wondering which mattered more - the light washing over the skin or contacting the eyes - Irbahim created tiny, rat-sized contact lenses. He found that when rats were wearing the contact lenses, which let only green light through, they similarly showed less discomfort.

Green light exposure has been found to significantly reduce migraine intensity and discomfort from fibromyalgia. In Kaiyan Medical we can create your green light therapy device to treat migraine and other conditions.

More References

https://www.freethink.com/articles/green-light-therapy

https://allaylamp.com/blogs/light-reading/green-light-therapy

https://www.nccih.nih.gov/health/statistics-from-the-national-health-interview-survey

https://sleep.med.harvard.edu/news/356/Green+Light+Affects+Circadian+Rhythm

Therapeutic and Aesthetic Uses of Blue & Red Light Therapy Together

Acne vulgaris remains one of the most common dermatologic disorders. Clinicians are always searching for new therapies to utilize in their therapeutic armamentarium for this common skin concern. We have many medical therapies at our disposal and these have proven useful in many cases in controlling the disease process. However, some patients need or want other therapies, and laser and light treatments for acne vulgaris have become popular over the past several years.

Regarding LED light therapy for the skin, “There is a science to support it” says Angela Lamb, director of the Westside Mount Sinai Dermatology Practice,

“but it’s important to know its limitations.”

Exposing your skin to different forms of low-level LED light does have anti-bacterial and anti-inflammatory benefits, which is why they’re commonly used for treating redness or acne. Blue light therapy in the right wavelength can be FDA-cleared.

Light Therapy with Aduro Mask

Other blue light trials have supported the efficacy of blue light. Papageorgiou described their experiences with phototherapy comparing a mixed blue and red light system (415 and 660nm) with blue light therapy alone and white light therapy. The results showed that the combination of blue and red light decreased inflammatory acne vulgaris lesions by 76 percent versus 58 percent in the blue light alone group, which were both better than white light (25%). Meffert reported experiences with a high-energy, broad-spectrum, blue light source that combined blue light and UVA with a wavelength of 410 to 420nm and noted marked improvement in patients with pustular acne vulgaris after 10 treatments.

There are a variety of at-home light treatments out there like the Aduro mask (which is patented with medical grade quality) who uses red, orange, purple, infrared, cyan, blue,green and yellow light — but typically what you’ll see on shelves are ones harnessing blue or red light . Blue light is a shorter wavelength that destroys acne-causing bacteria on the skin’s surface, while red light penetrates deeper to help with inflammation, but Hooman Khorasani, the chief of the division of Dermatologic and Cosmetic Surgery at the Icahn School of Medicine at Mount Sinai, says that both blue- and red-light therapy “may reduce the size of the sebaceous glands, so you don’t produce as much oil.”

Blue & Red Light Therapy

The good thing about light therapy is that experts say that there aren’t really downsides if you’re willing to give it a shot. Light treatments have been shown to be relatively safe, with minimal side effects. For acne, Khorasani notes that LED devices won’t take the place of acne fighters like retinoids; instead, they should be used in concert with a multipronged treatment plan — and never for severe acne. If you are combining them with retinoids, Lamb also suggests alternating the days you use either of them, to avoid photosensitivity.

When you combine the blue and red light using the aduro mask, you can get a pink/purple amazing color that will help remove the p-acne causing bacteria from the skin while purifying and cleansing it. Also, you will speed up the healing process and rejuvenate the skin cells increasing the cell regeneration.

More references

https://www.accessdata.fda.gov/cdrh_docs/pdf9/K093963.pdf

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013592

Sigurdsson V, Knulst AC, van Weelden H. Phototherapy of acne vulgaris with visible light. Dermatology. 1997;194:256–260. [PubMed] [Google Scholar]

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Healing Muscular Pain with Light Therapy

Light Therapy Healing Muscular Pain

When it comes to pain, we could hardly avert it! Especially the muscle pain. Given that the human body has over 600 muscles, it is tough to avoid muscle pain. Evidently, one out of three Americans is affected by muscle pain annually.

Not only this, Musculoskeletal pain affects around 116 million Americans, which results in poor productivity, missed work or school, fatigue, and lost interest in work.

But doesn’t we treatments for this chronic pain? Of course, we do have several options. Currently, therapies available consist of non-steroidal anti-inflammatory drugs, steroid injections, pain medications, and surgery. Each of these has its own specific risk profiles.

What we need now is an effective solution that is less time-consuming, low risk, safe and non-invasive, and yet cost-effective. All these features are available in treatment; we call Low Laser Light Therapy (LLLT). Light therapy has been in the medical field over the past forty years. Light therapy has been demonstrated to lessen inflammation and edema, promote healing in a range of musculoskeletal pathologies. LLLT is being accepted around the globe. This is an advanced, cost-effective, non-invasive therapy for pain that could elevate the quality of life while reducing your financial strains. The causes of muscular pain are numerous. Hence, LLLT helps people from all fields like sports, fitness, medical, and even old age.


Mechanism of LLLT

In this process, light with a wavelength in the red to the near-infrared region of the spectrum (660nm–905nm) is employed on the skin surface. The reason for using these wavelengths is that they have the ability to penetrate the skin and soft/hard tissues. From various conducted clinical trials, this treatment is proven to have a good effect on pain, inflammation, and repairing of the tissues. The therapy goes from 30 to 120 seconds or more a week, depending upon the pain's severity.

Based on the tissue condition, the therapy can go on for weeks or months. LLLT has resulted in relief and reduction of inflammation, pain relief, and accelerated tissue regeneration.

But how does the light actually work?

LLLT in the Treatment of Pain

Do you know that many acute orthopedic conditions such as strains, sprains, muscular back pain, frozen shoulder, neck and back pain, etc., are amenable to Low Laser Light Therapy (LLLT)?

The Infra-Red light relieves pain in a different section of the body and increases relaxation sensation while also comforting the muscles. LLLT has been shown to enhance the multiplication of cells like fibroblasts, keratinocytes, endothelial cells, and lymphocytes. Fibroblasts and keratinocytes are two major cell types that respond to the inflammatory phase in the repair/regeneration process.

LLLT can enhance neovascularization, promote angiogenesis, and increase collagen synthesis to succor in the healing of acute and chronic wounds. The LED light sessions have shown the ability to heal skin, nerves, tendons, cartilage, and bones. Low-intensity LLLT stimulates mitochondria and also enhances the mitochondrial membrane potential.

The peripheral nerve endings of nociceptors (also known as the pain receptors), consisting of the thinly myelinated and unmyelinated, slow-conducting C fibers, lie within the epidermis. This complex network converts harmful stimuli into action potentials. Moreover, these nerve endings lie on the surface or superficial in nature, making the LLLT wavelength penetration work easy.


Hence, with the rise of chronic pain in different countries, it is imperative to validate cost-effective and safe techniques for managing painful conditions, allowing people to live active and productive lives. Light therapy is constantly evolving in relieving muscular pain. It improves the muscle's endurance, reduces muscle soreness, joint pain, and inflammation.

It’s time to let go of the pain!!

Experience the difference with light therapy from Kaiyan Medical.

More References:

https://pubmed.ncbi.nlm.nih.gov/12605431/

https://pubmed.ncbi.nlm.nih.gov/27472858/

https://arthritis-research.biomedcentral.com/track/pdf/10.1186/s13075-015-0882-0

https://www.sciencedirect.com/science/article/pii/S0004951414601276?via%3Dihub

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743666/

Treating Glaucoma with Green Light Therapy

According to the National Eye Institute, glaucoma is the third leading cause of blindness in the U.S cataracts and macular degeneration rank first and second, respectively. There are an estimated 2,218,000 patients who suffer from glaucoma (approx. 1 in 136 or 0.74%).

What is Glaucoma

Glaucoma is a disease of the optic nerve often caused by an abnormally high pressure the eye (also called IOP, intra-ocular pressure). It is one of the leading factor for blindness. It can occur at any age but is more common for people over the age of 60. The vision loss due to glaucoma can't be recovered and many forms of glaucoma have no warning signs at an early stage, so it is important that we do regular eye exam or get prevention as early as possible.  

Currently, there are 3 Keys that allow for a more accurate diagnosis of glaucoma:
An elevation of intraocular pressure
Changes in the optic nerve
• Peripheral field loss

Diagnosis

Your doctor will review your medical history and conduct a comprehensive eye examination. He or she may perform several tests, including:

  • Measuring intraocular pressure (tonometry)
  • Testing for optic nerve damage with a dilated eye examination and imaging tests
  • Checking for areas of vision loss (visual field test)
  • Measuring corneal thickness (pachymetry)
  • Inspecting the drainage angle (gonioscopy)
Medical Treatment

The damage caused by glaucoma can't be reversed. But treatment and regular checkups can help slow or prevent vision loss, especially if you catch the disease in its early stages.  Glaucoma is treated by lowering your eye pressure (intraocular pressure). Depending on your situation, your options may include prescription eyedrops, oral medications, laser treatment, surgery or a combination of any of these.

However, the method of treatment of glaucoma is mainly of medication, which can lower the intra-ocular pressure, but also many medication would also block aqueous production. It is similar to the condition that a patient with hypertension taking medications to decrease the production of blood to reduce the blood pressure. That is harmful to the eye health.

In Singapore, the mean direct cost of glaucoma treatment with glaucoma medications alone per patient over 10 years was SGD 2042.47 (± 2078.54) or US$1,592.86 (±1620.99), while the mean cost of surgery was SGD 8038.75 (± 2829.4) or US$6,269.18 (± 2206.56) and laser was SGD 1163.63 (± 532.9) or US$907.48 (± 415.59).

Green light therapy is way cheaper and can lead to great results


Green Light Treatment

One of the biggest advantage of light therapy is that there is no side-effect like medication and it can be used at an early stage for prevention.

Scientists and researchers first began to study light therapy in the treatment of glaucoma in 1948. According to R. B. Zaretskaya, MD’s research, published in American Journal of Ophthalmology, it shows that, while the red light has a pressure raising effect, the effects of green light are greater than white light even at a higher brightness. So, green light should be considered a therapy for the reduction of intra-ocular pressure in glaucoma.

The following important experiment was done by R. B. Zaretskaya, MD, also published in the American Journal of Ophthalmology, showed that eye pressure was lowed for patients wearing green spectacles, also with fluctuation of eye pressure decreasing. These patients were required to a 10 minute exposure of green light with an intensity of 1.4 lux. Pressures were then measured at every half hour until pressures returned to baseline.

The conclusion indicates that green light (mu delta) has a pressure lower affect in the majority of patients 82% and the average pressure lower affect was 5 mm Hg and this effect persisted for 4 hours after a brief 10 minute exposure.  

The second article also by R. B. Zaretskaya, MD, which was published in the American Journal of Ophthalmology 1948 31: 985-989 refers about 19 patients that were studied and pressures were determined 3 times a day. Once at 7:00 AM (still in bed), 1:00 PM and then between 7:00 and 8:00 PM. Medications were withheld for a day or two and then green spectacles were given on the second day for full time wear. The spectacles were a hue corresponding to 511 nm and a daylight transparency of 21%. In a certain number of cases, the green spectacles were combined with a greatly reduced strength of pilocarpine. One group had a combination of green glasses and adrenalin (1:1,000) which was also made to test Kravkov’s statement that the installation of adrenalin might increase the eyes sensitivity to green.

Results of this study showed that IOP showed a pronounced tendency to decrease in patients wearing green spectacles.  The fluctuation of IOP during the day was also found to decrease in patients wearing green glasses.  There was an appreciable effect when the use of green spectacles was combined with very small dosages of pilocarpine (0.5 percent).  20 out of 25 eyes had an expressed decrease in IOP as well as a decrease in fluctuations. The pressures decreased by  6.0 mm Hg in 8 cases, 10 mm Hg in 9 cases and 10 mm Hg and more in 3 cases. The results were more striking when combined with small dosages of adrenalin.

Conclusions:
Green spectacles prescribed with a total withdrawal from Pilocarpine produces a decrease in IOP
The affects are most pronounced when used with the administration of small doses of adrenalin
• Mechanism of action is proposed to be on the color receptors of the human eye
• Green light brings about a definite arrangement in the autonomic nervous system and thus affects the neurovascular system of the eye

How to Do a Green Light Therapy Treatment?

Consistency and proper use is key for effective green light therapy. For optimal results with a high-quality device like the ones in Kaiyan, follow these basics for general wellness benefits:

  • Expose your eyes for best results
  • 10-minute treatment each time
  • Daily use is ideal
  • Any time of day
The Future for Green Light and Glaucoma

As we also know that green light could also treat migraine as well as glaucoma, and both migraine and glaucoma are disease of nerve, we may want to know is there connection between these two illness, both of which would cause the pain in the front part of our brain. Hope future research would find out.

References

Conference speech presented at the International Syntonic Light Conference held in St. Pete Beach, Fl , April 28th – May 1st

https://www.healingtheeye.com/Articles/Syntonic_Light_Therapy_Glaucoma.html

https://www.healingtheeye.com/Articles/AJO_IOP_%20light.pdf

https://www.mayoclinic.org/diseases-conditions/glaucoma/diagnosis-treatment/drc-20372846#:~:text=Glaucoma%20is%20treated%20by%20lowering,combination%20of%20any%20of%20these.

https://iovs.arvojournals.org/article.aspx?articleid=2360086#:~:text=The%20mean%20direct%20cost%20of,US%24907.48%20(%C2%B1%20415.59).

R. B. Zaretskaya, MD. Intraocular Pressure of Normal and Glaucomatous Eyes as Affected by Accessory Light Stimuli. American Journal of Ophthalmology 1948 – 31-721-727.

The Key for Better Sex - Red Light Therapy

The famous fitness coach Ben Greenfield uses red light naked every morning. He flips a switch, flooding the room with a bright red glow. Then he stands naked in the red light for 20 minutes.

“It seems to like, wake you up a little bit; it kind of simulates sunrise,” Greenfield tells. “And it’s almost mildly addictive — the feel-good effect of how you feel after you use one of these.”

Greenfield, a 39-year-old fitness instructor, is an evangelist for red light therapy, a treatment that’s increasingly popular in the world of sports, beauty, and biohacking. Some converts to red-light therapy treatment soak in the ruddy glow for a very personal reason.

Red Light for Testosterone
Red Light Therapy

Light therapy has been for hundreds of years. Recently, we can trace it back to 1967 with Hungarian scientists, red light therapy, scientifically known as photobiomodulation or low-level laser (light) therapy, has made a comeback in the last two decades.

Michael Hamblin, a researcher at Massachusetts General Hospital and professor at Harvard Medical School, explains in a 2017 research paper on the topic that the treatment was confined to a “SCIENTIFIC WASTELAND,” and widely considered “SNAKE OIL.”

But recent studies suggest red-light therapy can improve skin quality, addictions, pets’ mood, sleep quality, depression, muscle recovery, and relieve pain.

Indeed, some studies suggest light therapy stimulates mitochondria, a.k.a. the “powerhouse” of a cell, and increases the production of adenosine triphosphate, the organic chemical that carries energy in the body and plays a big role in metabolism.

Bio-hacking yourself

In Kaiyan Medical, we are on a constant quest to optimize our brains and bodies. Some studies have actually demonstrated that exposing the torso or the testes to light can potentially increase testosterone. In fact, studies on the effects of light on the testes go way back to 1939, when researchers exposed various parts of men’s bodies to UV light. They found that men’s testosterone levels went up by 120% when the participants’ chests were exposed to UV light, and they went up by 200% with UV exposure to the genital area.

Sunlight exposure directly to the testes reportedly has an even more profound effect, boosting production in Leydig cells (the cells that produce testosterone) by an average of 200%

The theory is this: while sunlight has many beneficial effects, such as vitamin D production and improved mood, it is not without its downsides. Too much exposure to sunlight, particularly to sensitive areas like the skin around your precious ball sac, can create sunburn, excess radiation, inflammation and damage. And let’s face it: you don’t want a shrunken, shriveled, dehydrated dick, no matter how impressive the tan.

Red light, however, is different than sunlight. Red light is comprised of light wavelengths in the range of 600–950 nanometers (nm). According to red light therapy proponents, red light works to stimulate ATP production, increase energy available to the cell and in particular, increase the activity of the Leydig cells in your testes, which are the cells responsible for testosterone production.

Optimizing Sex

In the last five years, light therapy researchers and red-light therapy companies set their sights on men like Greenfield — the guy who gets naked every morning in his home office.  “The impact of [low-light therapy] on sexual health is an emerging field, but I see its potential to improve sexual function and libido with recent studies,” Hamblin says. “It has been shown to improve sperm function and may have applications in increasing fertility in both men and women.”  Research on sexual health applications of red-light therapy is relatively minimal in men, and basically nonexistent for women. A few studies in animals suggest red light therapy might influence LEYDIG CELLS — the body’s sperm producers, which live in the testicles. Another study in humans suggests red light therapy can increase testosterone levels and sexual satisfaction.

Don't let the fear defeat you

Sexual health issues — from “low T” to erectile dysfunction — can be challenging to treat because of the social stigma, Goldstein explains. There’s a “fear,” the urologist says. Many men are ashamed and avoid seeing a doctor.  “If they can get something over the counter that's purported to help them, millions of men will be willing to try it and maybe they would never buy it again,” Goldstein tells.  “Good advertising and good marketing will create a market for a product, whether it's proven to be of value or not.”  

Reduce Infertility

One of the biggest concerns for those who suffer from Low-T is infertility. Several studies show that red light therapy helps increase sperm motility, which is essential for successful impregnation. In 2017, researchers from the University of California, San Diego, found that sperm exposed to 630nm red light increased sperm swimming speed and force.

A similar study by researchers from Iran found an after exposing sperm to an 830nm NIR light device. Sperm motility is associated with cellular energy; more energized sperm will swim with greater vigor. This is a vital component of male reproductive health, and success in improving sperm motility points to the use of red light therapy as a way to treat male infertility.

Red Light for Testosterone
Feeling like a super hero

On top of using red light, both Greenfield and Wiles eat healthy, work out regularly, and practice stress-management techniques. Which habit, or a combination of each, helps them “optimize” their sex life or their physical health isn’t clear.

Even though the research doesn’t match their claims — yet— Greenfield and Wiles have no intention of slowing down.  “Before I go and give a presentation or if I'm giving a lecture or even if I'm just seeing a patient in clinic, I'll go ahead and throw that thing on and I will feel like a million bucks," Wiles says. "I’ve noticed increased overall sexual health, sexual satisfaction, and stamina."  Recently, Greenfield has been shining the light for one very specific reason: He and his wife are trying for a baby.  “Sometimes if I know I've got like a date night with my wife or we're going to have sex that night, I'll wait until the evening to do the treatment because the immediate effects are even better, especially the blood flow," Greenfield says.  "Erectile quality is just better right after you use it.”

More References

https://platinumtherapylights.com/blogs/news/red-light-therapy-for-boosting-testosterone

https://www.inverse.com/mind-body/red-light-therapy#:~:text=A%20few%20studies%20in%20animals,testosterone%20levels%20and%20sexual%20satisfaction.

Sculpting your Body with Green Light

Wouldn’t it be great if we could each reduce a couple of inches off our waist without having to diet or exercise for so long? Losing weight and fat is one of the most common health goals, both for medical and cosmetic reasons. For years, millions of people have tried different pills, injections, “natural” herbs, and many products that are supposed to help us reduce weight. Unfortunately, these usually don’t work

Clinical trial

Many people trying to lose weight just want to look better in the mirror, or at the beach. A wide variety of therapies to target fat and improve appearance are called “body contouring” or “body sculpting”, some surgical, others noninvasive. But many of them don’t work, or produce troublesome side effects. Green light therapy is completely natural & noninvasive and has proven to be an effective option for changing the way your body looks.

In the clinical trial NCT03647748 a double-blind, placebo-controlled randomized evaluation of the effect of Cellulize, a green light low-level laser system for aesthetic use for the non-invasive reduction in fat layer for body contouring and reduction of cellulite.

Device Description

The Cellulize is a non-invasive green light system with a power output of 105mW/cm2, consisting of 150 light-emitting diodes (LEDs) that emit visible light at a nominal wavelength of 532nm ± 3nm (visible green light spectrum) and a spectral bandwidth of 10nm. Cellulize® is indicated for uses non-invasive dermatological aesthetic treatment for the reduction of circumference of hips, waist, and thighs. The Massager component is indicated for the temporary reduction in the appearance of cellulite.

Clinical Testing

Cumulative circumferences of waist, hip, left and right thighs for each patient was calculated before and after treatment. Three main points were concluded as a result of the study:

1. Cellulize causes immediate inch loss in subjects after a regimen of six treatments of 32 minutes (8 minutes on each of four positions) compared to individuals subjected to a placebo device for equivalent treatment. In a typical regimen, patients lost an average cumulative of 2.67 inches of circumference compared to the placebo average of 0.5 inches. This meets the anticipated primary outcome measure “Average Change in Inches of Total Circumference Measurements for the effect of Cellulize, a LED 532nm green light low-level laser system for aesthetic use for the non-invasive reduction in fat layer for body contouring from baseline measurements, and after treatment. ”

Figure 1, below, shows the graphical summary of inch loss for patients in the Cellulize active group and the Placebo control group respectively. Table 1 gives the mean values for both groups as well as the standard deviation for the “after” measurements, as well as 7-day and 14-day follow-ups relative to the “before” measurements for each patient:

Figure 1

2. While the durability of effect is also impacted by extrinsic factors after treatments such as diet, it was demonstrated that subjects were more likely to show continued inch loss upon following up with each subject at 7 days and again at 14 days. In general, patients undergoing active Cellulize 532nm green light continued losing some inch with an average continued loss of an additional 1.20 inches for a total average inch loss of 3.87 inches where average placebo measurements after 14 days yielded a net gain (not a loss) of 0.875 inches. This implies that the green light treatment meets the expected primary outcome of demonstrated durability of effect after a short -term follows up of 2 weeks.

3 Finally, the effect of Cellulize LED 532nm green light without any other intervention was measured for its effect on cellulite as part of the study. The Nurnberger-Muller Scale (NMS), a four-stage scale used as an industry standard to classify stage or degree of cellulite and to determine the change in stage or degree of cellulite following treatment intervention, was used to ensure consistent evaluation standards. Results from the active device as well as placebo both showed that cellulite, in general, did not decrease on the back of thigh/buttocks for subjects after a single treatment of 532nm green light. This result failed to meet the anticipated primary outcome measure of decreasing the appearance of cellulite as a measure of the Nurnberger-Muller Scale (NMS) from baseline to completion of treatment for the thigh/buttock area.

Fat Reducing Low-Level Laser — OLI

The FDA product classification code, OLI, has a guidance document which is the special control for this product, Guidance for Industry and FDA Staff — Class II Special Controls Guidance Document: Low-Level Laser System for Aesthetic Use. According to the guidance document, FDA believes that special controls, when combined with the general controls, will be sufficient to provide reasonable assurance of the safety and effectiveness of the low-level laser system for aesthetic use. Cellulize complies with all of the standards outlined in the special controls consensus standards.

To learn more about OLI products, you can visit https://fda.report/Product-Code/OLI

Kaiyan Medical

Here in Kaiyan Medical, we are pioneers and innovators with light therapy. We keep developing technologies with green light and trying to reach more markets.

kaiyanmedical.com


References

Effects of Green Light Therapy on Body Contouring and Cellulite - Full Text View …
Primary Outcome Measures : Average Change in Inches of Total Circumference Measurements [ Time Frame: 2 weeks ] Average…clinicaltrials.gov

Duarte FO, et al. Can low-level laser therapy (LLLT) associated with an aerobic plus resistance training change the cardiometabolic risk in obese women? A placebo-controlled clinical trial. J Photochem Photobiol B. 2015 Dec;153:103–10.

da Silveira Campos RM, Dâmaso AR, et al. The effects of exercise training associated with low-level laser therapy on biomarkers of adipose tissue transdifferentiation in obese women. Lasers in Medical Science. 2018 Aug;33(6):1245–1254.